TW200640884A - Novel 3-aryl-1,2-benzisoxazole derivatives, compositions containing same and use thereof - Google Patents
Novel 3-aryl-1,2-benzisoxazole derivatives, compositions containing same and use thereofInfo
- Publication number
- TW200640884A TW200640884A TW095105684A TW95105684A TW200640884A TW 200640884 A TW200640884 A TW 200640884A TW 095105684 A TW095105684 A TW 095105684A TW 95105684 A TW95105684 A TW 95105684A TW 200640884 A TW200640884 A TW 200640884A
- Authority
- TW
- Taiwan
- Prior art keywords
- novel
- nr5r6
- nitro
- represent
- halogen
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 3
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000004475 heteroaralkyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0501801A FR2882361A1 (fr) | 2005-02-22 | 2005-02-22 | Nouveaux derives de 3-aryl-1,2-benzisoxazole, compositions les contenant et leur utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200640884A true TW200640884A (en) | 2006-12-01 |
Family
ID=35058405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095105684A TW200640884A (en) | 2005-02-22 | 2006-02-21 | Novel 3-aryl-1,2-benzisoxazole derivatives, compositions containing same and use thereof |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20080070960A1 (zh) |
| EP (1) | EP1861381A1 (zh) |
| JP (1) | JP2008531493A (zh) |
| KR (1) | KR20070110102A (zh) |
| CN (1) | CN101146780A (zh) |
| AR (1) | AR053684A1 (zh) |
| AU (1) | AU2006217799A1 (zh) |
| BR (1) | BRPI0606178A2 (zh) |
| CA (1) | CA2597781A1 (zh) |
| EA (1) | EA200701798A1 (zh) |
| FR (1) | FR2882361A1 (zh) |
| IL (1) | IL185166A0 (zh) |
| MA (1) | MA29265B1 (zh) |
| MX (1) | MX2007010278A (zh) |
| NO (1) | NO20074631L (zh) |
| TW (1) | TW200640884A (zh) |
| UY (1) | UY29390A1 (zh) |
| WO (1) | WO2006090052A1 (zh) |
| ZA (1) | ZA200707080B (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2907453B1 (fr) * | 2006-10-24 | 2008-12-26 | Sanofi Aventis Sa | Nouveaux derives du fluorene,compositions les contenant et utilisation |
| AR077405A1 (es) | 2009-07-10 | 2011-08-24 | Sanofi Aventis | Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer |
| FR2949467B1 (fr) | 2009-09-03 | 2011-11-25 | Sanofi Aventis | Nouveaux derives de 5,6,7,8-tetrahydroindolizine inhibiteurs d'hsp90, compositions les contenant et utilisation |
| EP2934145B1 (en) * | 2012-12-19 | 2017-11-15 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6884814B2 (en) * | 2001-12-13 | 2005-04-26 | Wyeth | Phenyl benzisoxazoles as estrogenic agents |
| EA009919B1 (ru) * | 2003-02-11 | 2008-04-28 | Вернэлис (Кембридж) Лимитед | Соединения изоксазола |
| US7538224B2 (en) * | 2003-06-27 | 2009-05-26 | Kyowa Hakko Kogyo Co., Ltd. | Hsp90 family protein inhibitors |
| CA2536089A1 (en) * | 2003-08-20 | 2005-03-03 | Eli Lilly And Company | Ppar modulators |
-
2005
- 2005-02-22 FR FR0501801A patent/FR2882361A1/fr active Pending
-
2006
- 2006-02-20 CA CA002597781A patent/CA2597781A1/fr not_active Abandoned
- 2006-02-20 EP EP06709343A patent/EP1861381A1/fr not_active Withdrawn
- 2006-02-20 KR KR1020077021865A patent/KR20070110102A/ko not_active Withdrawn
- 2006-02-20 MX MX2007010278A patent/MX2007010278A/es not_active Application Discontinuation
- 2006-02-20 ZA ZA200707080A patent/ZA200707080B/xx unknown
- 2006-02-20 EA EA200701798A patent/EA200701798A1/ru unknown
- 2006-02-20 WO PCT/FR2006/000375 patent/WO2006090052A1/fr not_active Ceased
- 2006-02-20 AU AU2006217799A patent/AU2006217799A1/en not_active Abandoned
- 2006-02-20 CN CNA2006800095240A patent/CN101146780A/zh active Pending
- 2006-02-20 AR ARP060100604A patent/AR053684A1/es unknown
- 2006-02-20 JP JP2007555668A patent/JP2008531493A/ja active Pending
- 2006-02-20 BR BRPI0606178-8A patent/BRPI0606178A2/pt not_active IP Right Cessation
- 2006-02-21 TW TW095105684A patent/TW200640884A/zh unknown
- 2006-02-22 UY UY29390A patent/UY29390A1/es unknown
-
2007
- 2007-08-09 IL IL185166A patent/IL185166A0/en unknown
- 2007-08-20 US US11/841,128 patent/US20080070960A1/en not_active Abandoned
- 2007-08-23 MA MA30161A patent/MA29265B1/fr unknown
- 2007-09-11 NO NO20074631A patent/NO20074631L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0606178A2 (pt) | 2009-06-02 |
| FR2882361A1 (fr) | 2006-08-25 |
| KR20070110102A (ko) | 2007-11-15 |
| WO2006090052A1 (fr) | 2006-08-31 |
| AU2006217799A1 (en) | 2006-08-31 |
| MX2007010278A (es) | 2007-11-07 |
| CA2597781A1 (fr) | 2006-08-31 |
| ZA200707080B (en) | 2008-11-26 |
| EP1861381A1 (fr) | 2007-12-05 |
| IL185166A0 (en) | 2007-12-03 |
| JP2008531493A (ja) | 2008-08-14 |
| NO20074631L (no) | 2007-11-20 |
| CN101146780A (zh) | 2008-03-19 |
| MA29265B1 (fr) | 2008-02-01 |
| AR053684A1 (es) | 2007-05-16 |
| US20080070960A1 (en) | 2008-03-20 |
| UY29390A1 (es) | 2006-10-02 |
| EA200701798A1 (ru) | 2008-02-28 |
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