TW200505854A - Process for preparing high-purity hydroxyindolylglyoxylamides - Google Patents
Process for preparing high-purity hydroxyindolylglyoxylamidesInfo
- Publication number
- TW200505854A TW200505854A TW092121702A TW92121702A TW200505854A TW 200505854 A TW200505854 A TW 200505854A TW 092121702 A TW092121702 A TW 092121702A TW 92121702 A TW92121702 A TW 92121702A TW 200505854 A TW200505854 A TW 200505854A
- Authority
- TW
- Taiwan
- Prior art keywords
- hydroxyindolylglyoxylamides
- purity
- preparing high
- preparing
- relates
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- IZNRZZVWBDWWKJ-UHFFFAOYSA-N n-hydroxy-2-(1h-indol-2-yl)-2-oxoacetamide Chemical class C1=CC=C2NC(C(=O)C(=O)NO)=CC2=C1 IZNRZZVWBDWWKJ-UHFFFAOYSA-N 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40023602P | 2002-08-01 | 2002-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200505854A true TW200505854A (en) | 2005-02-16 |
Family
ID=31495805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW092121702A TW200505854A (en) | 2002-08-01 | 2003-08-07 | Process for preparing high-purity hydroxyindolylglyoxylamides |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7122674B2 (zh) |
| EP (1) | EP1525197A1 (zh) |
| JP (1) | JP2006503002A (zh) |
| KR (1) | KR20050026095A (zh) |
| CN (1) | CN1325490C (zh) |
| AU (1) | AU2003255341A1 (zh) |
| BR (1) | BR0313467A (zh) |
| CA (1) | CA2493982A1 (zh) |
| HR (1) | HRP20050201A2 (zh) |
| IL (1) | IL165949A0 (zh) |
| MX (1) | MXPA05001227A (zh) |
| NO (1) | NO20051086L (zh) |
| NZ (1) | NZ537947A (zh) |
| PL (1) | PL375492A1 (zh) |
| RU (1) | RU2315046C2 (zh) |
| TW (1) | TW200505854A (zh) |
| WO (1) | WO2004013127A1 (zh) |
| ZA (1) | ZA200500454B (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0414313A (pt) | 2003-09-11 | 2006-11-07 | Kemia Inc | inibidores de citocinas |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2953575A (en) * | 1955-11-08 | 1960-09-20 | Houdry Process Corp | Preparation of indole |
| CH375712A (de) | 1959-01-16 | 1964-03-15 | Sandoz Ag | Verfahren zur Herstellung von neuen, hydroxylierten Indol-Derivaten |
| BE759266A (fr) | 1969-11-24 | 1971-05-24 | Hoffmann La Roche | Procede pour la preparation de derives de l'indole |
| US3976639A (en) * | 1970-11-04 | 1976-08-24 | Hoffmann-La Roche Inc. | Intermediates for indoles |
| DE19636150A1 (de) * | 1996-09-06 | 1998-03-12 | Asta Medica Ag | N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung |
| DE19818964A1 (de) * | 1998-04-28 | 1999-11-04 | Dresden Arzneimittel | Neue Hydroxyindole, deren Verwendung als Inhibitoren der Phospodiesterase 4 und Verfahren zu deren Herstellung |
| ATE330955T1 (de) | 1998-04-28 | 2006-07-15 | Elbion Ag | Indolderivate und deren verwendung als inhibitoren der phosphodiesterase 4. |
| US6160127A (en) | 1998-07-15 | 2000-12-12 | Bristol-Myers Squibb Company | Process for the preparation of substituted indoles |
-
2003
- 2003-07-31 RU RU2005105581/04A patent/RU2315046C2/ru not_active IP Right Cessation
- 2003-07-31 HR HR20050201A patent/HRP20050201A2/hr not_active Application Discontinuation
- 2003-07-31 AU AU2003255341A patent/AU2003255341A1/en not_active Abandoned
- 2003-07-31 NZ NZ537947A patent/NZ537947A/en unknown
- 2003-07-31 WO PCT/EP2003/008500 patent/WO2004013127A1/de not_active Ceased
- 2003-07-31 BR BR0313467-9A patent/BR0313467A/pt not_active IP Right Cessation
- 2003-07-31 CN CNB038185377A patent/CN1325490C/zh not_active Expired - Fee Related
- 2003-07-31 CA CA002493982A patent/CA2493982A1/en not_active Abandoned
- 2003-07-31 PL PL03375492A patent/PL375492A1/xx unknown
- 2003-07-31 MX MXPA05001227A patent/MXPA05001227A/es unknown
- 2003-07-31 EP EP03766389A patent/EP1525197A1/de not_active Withdrawn
- 2003-07-31 JP JP2004525409A patent/JP2006503002A/ja not_active Withdrawn
- 2003-07-31 KR KR1020057001815A patent/KR20050026095A/ko not_active Withdrawn
- 2003-07-31 US US10/631,475 patent/US7122674B2/en not_active Expired - Fee Related
- 2003-08-07 TW TW092121702A patent/TW200505854A/zh unknown
-
2004
- 2004-12-23 IL IL16594904A patent/IL165949A0/xx unknown
-
2005
- 2005-01-18 ZA ZA200500454A patent/ZA200500454B/en unknown
- 2005-02-28 NO NO20051086A patent/NO20051086L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL375492A1 (en) | 2005-11-28 |
| HRP20050201A2 (en) | 2005-04-30 |
| MXPA05001227A (es) | 2005-06-08 |
| RU2315046C2 (ru) | 2008-01-20 |
| AU2003255341A1 (en) | 2004-02-23 |
| CA2493982A1 (en) | 2004-02-12 |
| RU2005105581A (ru) | 2005-11-20 |
| ZA200500454B (en) | 2006-04-26 |
| NO20051086L (no) | 2005-05-02 |
| US20040063939A1 (en) | 2004-04-01 |
| US7122674B2 (en) | 2006-10-17 |
| JP2006503002A (ja) | 2006-01-26 |
| KR20050026095A (ko) | 2005-03-14 |
| NZ537947A (en) | 2006-11-30 |
| IL165949A0 (en) | 2006-01-15 |
| CN1325490C (zh) | 2007-07-11 |
| BR0313467A (pt) | 2005-07-05 |
| WO2004013127A1 (de) | 2004-02-12 |
| EP1525197A1 (de) | 2005-04-27 |
| CN1671692A (zh) | 2005-09-21 |
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