TW200407134A - Nicotin-or isonicotin benzothiazole derivatives - Google Patents

Nicotin-or isonicotin benzothiazole derivatives

Info

Publication number: TW200407134A
Authority: TW; Taiwan
Prior art keywords: lower alkyl; morpholinyl; cycloalkyl; substituted; alkoxy
Prior art date: 2001-11-19

Application number

TW091133371A

Other languages

English (en)

Inventor

Alexander Flohr

Roland Jakob-Roetne

Roger David Norcross

Claus Riemer

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-19

Filing date

2002-11-14

Publication date

2004-05-16

2002-11-14 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2004-05-16 Publication of TW200407134A publication Critical patent/TW200407134A/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

TW091133371A 2001-11-19 2002-11-14 Nicotin-or isonicotin benzothiazole derivatives TW200407134A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01127312		2001-11-19

Publications (1)

Publication Number	Publication Date
TW200407134A true TW200407134A (en)	2004-05-16

Family

ID=8179263

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW091133371A TW200407134A (en)	2001-11-19	2002-11-14	Nicotin-or isonicotin benzothiazole derivatives

Country Status (38)

Country	Link
US (1)	US6620811B2 (zh)
EP (1)	EP1448198B1 (zh)
JP (1)	JP4226474B2 (zh)
KR (1)	KR100577110B1 (zh)
CN (1)	CN100546580C (zh)
AR (1)	AR039367A1 (zh)
AT (1)	ATE376831T1 (zh)
AU (1)	AU2002351955B2 (zh)
BR (1)	BR0214245A (zh)
CA (1)	CA2467552C (zh)
DE (1)	DE60223278T2 (zh)
DK (1)	DK1448198T3 (zh)
EA (1)	EA007502B1 (zh)
EC (1)	ECSP045109A (zh)
ES (1)	ES2294187T3 (zh)
GT (1)	GT200200232A (zh)
HR (1)	HRP20040396A2 (zh)
HU (1)	HUP0402161A3 (zh)
IL (2)	IL161623A0 (zh)
JO (1)	JO2290B1 (zh)
MA (1)	MA27083A1 (zh)
MX (1)	MXPA04004684A (zh)
MY (1)	MY126176A (zh)
NO (1)	NO20042576L (zh)
NZ (1)	NZ532802A (zh)
PA (1)	PA8558001A1 (zh)
PE (1)	PE20030713A1 (zh)
PL (1)	PL369517A1 (zh)
PT (1)	PT1448198E (zh)
RS (1)	RS39904A (zh)
RU (1)	RU2294933C2 (zh)
SI (1)	SI1448198T1 (zh)
TN (1)	TNSN04087A1 (zh)
TW (1)	TW200407134A (zh)
UA (1)	UA77462C2 (zh)
UY (1)	UY27542A1 (zh)
WO (1)	WO2003043636A1 (zh)
ZA (1)	ZA200403817B (zh)

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CA2413086C (en) *	2000-06-21	2011-06-28	Alexander Alanine	Benzothiazole derivatives
DK2266558T3 (en) *	2001-06-07	2017-07-31	Analgesic Neuropharmaceuticals Llc	TREATMENT OF NEUROPATHIC PAIN WITH RECEPTOR ANTAGONIST: N-METHYL-D-ASPARTATE (NMDA)
US6734179B2 (en) *	2001-12-12	2004-05-11	Hoffmann-La Roche Inc.	Benzothiazoles
US20050119251A1 (en) *	2001-12-21	2005-06-02	Jian-Min Fu	Nicotinamide derivatives and their use as therapeutic agents
US7390813B1 (en)	2001-12-21	2008-06-24	Xenon Pharmaceuticals Inc.	Pyridylpiperazines and aminonicotinamides and their use as therapeutic agents
US6872833B2 (en)	2003-04-14	2005-03-29	Hoffmann-La Roche Inc.	Adenosine receptor ligands
TWI376370B (en) *	2003-07-23	2012-11-11	Synta Pharmaceuticals Corp	Compounds for inflammation and immune-related uses
EP2316827B1 (en)	2003-07-30	2016-01-27	Xenon Pharmaceuticals Inc.	Piperazine derivatives and their use as therapeutic agents
CA2539314A1 (en) *	2003-09-19	2005-03-31	F. Hoffmann-La Roche Ag	Thiazolopyridine derivatives as adenosine receptor ligands
US7714009B2 (en)	2003-10-31	2010-05-11	Takeda Pharmaceutical Company Limited	Nitrogen-containing fused heterocyclic compounds
ES2629414T3 (es)	2003-12-26	2017-08-09	Kyowa Hakko Kirin Co., Ltd.	Derivados de tiazol
ATE537830T1 (de) *	2004-07-06	2012-01-15	Xenon Pharmaceuticals Inc	Nicotinamid derivate und ihre verwendung als therapeutika
AU2005263499B2 (en) *	2004-07-22	2010-11-25	F. Hoffmann-La Roche Ag	Substituted benzothiazoles
MX2007000638A (es) *	2004-07-22	2007-03-07	Hoffmann La Roche	Derivados de benzotiazol.
KR100823799B1 (ko) *	2004-07-22	2008-04-21	에프. 호프만-라 로슈 아게	벤조티아졸 유도체
EP1799667B1 (en) *	2004-09-20	2013-03-20	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as therapeutic agents
EP1830837B1 (en)	2004-09-20	2013-09-04	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
CA2580845A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
CA2580855A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CA2580860A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Pyridine derivatives for inhibiting human stearoyl-coa-desaturase
EP1804799B1 (en) *	2004-09-20	2013-08-21	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CN101083986A (zh) *	2004-09-20	2007-12-05	泽农医药公司	双环杂环衍生物及其作为硬脂酰CoA去饱和酶(SCD)抑制剂的用途
CA2580856A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
CN101084212A (zh) *	2004-09-20	2007-12-05	泽农医药公司	杂环衍生物及其作为硬脂酰CoA去饱和酶介导剂的用途
JP4633123B2 (ja) *	2004-11-05	2011-02-16	エフ．ホフマン−ラロシュアーゲー	イソニコチン酸誘導体の製造方法
US20060223849A1 (en) *	2005-03-14	2006-10-05	Mjalli Adnan M	Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors
MX2007015216A (es) *	2005-06-03	2008-02-22	Xenon Pharmaceuticals Inc	Derivados de aminotiazol y sus usos como agentes terapeuticos.
AU2007320906A1 (en) *	2006-11-13	2008-05-22	Pfizer Products Inc.	Diaryl, dipyridinyl and aryl-pyridinyl derivatives and uses thereof
CA2758961A1 (en)	2009-04-27	2010-11-04	High Point Pharmaceuticals, Llc	Substituted isoquinoline derivatives, pharmaceutical compositions, and methods of use as .beta.-secretase inhibitors
TWI548411B (zh)	2009-04-28	2016-09-11	Kyowa Hakko Kirin Co Ltd	Exercise disorder treatment
UA113383C2 (xx)	2009-09-02	2017-01-25		Терапевтичний агент для лікування тривожних розладів
UA110097C2 (uk)	2009-09-02	2015-11-25		Терапевтичний агент для лікування розладів настрою
US8450354B2 (en) *	2010-03-23	2013-05-28	High Point Pharmaceuticals, Llc	Substituted imidazo[1,2-b]pyridazine derivatives, pharmaceutical compositions, and methods of use as β-secretase inhibitors
JP5248585B2 (ja) *	2010-12-15	2013-07-31	ゼノン・ファーマシューティカルズ・インコーポレイテッド	治療薬としてのニコチンアミド誘導体およびそれらの使用
DE102011005232A1 (de)	2011-03-08	2012-09-13	AristoCon GmbH & Co. KG	Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
KR102160320B1 (ko)	2012-10-02	2020-09-28	에피테라퓨틱스 에이피에스	히스톤 탈메틸효소의 저해제
WO2020103930A1 (zh) *	2018-11-22	2020-05-28	上海科技大学	噻唑并环类化合物、其制备方法、中间体和应用
DE102019110904B4 (de) *	2019-04-26	2022-01-20	Helmholtz-Zentrum Dresden - Rossendorf E. V.	N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-acetamid-Derivate und deren Verwendung

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DE3374550D1 (en)	1982-12-21	1987-12-23	Johnsen Jorgensen Plastics Ltd	Dispensing container
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IL90337A0 (en) *	1988-05-24	1989-12-15	Pfizer	Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
CA2413086C (en)	2000-06-21	2011-06-28	Alexander Alanine	Benzothiazole derivatives

2002
- 2002-11-05 US US10/288,100 patent/US6620811B2/en not_active Expired - Lifetime
- 2002-11-11 ES ES02787632T patent/ES2294187T3/es not_active Expired - Lifetime
- 2002-11-11 DK DK02787632T patent/DK1448198T3/da active
- 2002-11-11 JP JP2003545317A patent/JP4226474B2/ja not_active Expired - Fee Related
- 2002-11-11 CA CA2467552A patent/CA2467552C/en not_active Expired - Fee Related
- 2002-11-11 IL IL16162302A patent/IL161623A0/xx unknown
- 2002-11-11 DE DE60223278T patent/DE60223278T2/de not_active Expired - Lifetime
- 2002-11-11 SI SI200230637T patent/SI1448198T1/sl unknown
- 2002-11-11 BR BR0214245-7A patent/BR0214245A/pt not_active IP Right Cessation
- 2002-11-11 KR KR1020047007638A patent/KR100577110B1/ko not_active Expired - Fee Related
- 2002-11-11 PL PL02369517A patent/PL369517A1/xx not_active Application Discontinuation
- 2002-11-11 RU RU2004118425/04A patent/RU2294933C2/ru not_active IP Right Cessation
- 2002-11-11 NZ NZ532802A patent/NZ532802A/en unknown
- 2002-11-11 UA UA20040604552A patent/UA77462C2/uk unknown
- 2002-11-11 AT AT02787632T patent/ATE376831T1/de active
- 2002-11-11 AU AU2002351955A patent/AU2002351955B2/en not_active Ceased
- 2002-11-11 MX MXPA04004684A patent/MXPA04004684A/es active IP Right Grant
- 2002-11-11 EA EA200400598A patent/EA007502B1/ru not_active IP Right Cessation
- 2002-11-11 HR HR20040396A patent/HRP20040396A2/hr not_active Application Discontinuation
- 2002-11-11 RS YU39904A patent/RS39904A/sr unknown
- 2002-11-11 EP EP02787632A patent/EP1448198B1/en not_active Expired - Lifetime
- 2002-11-11 WO PCT/EP2002/012562 patent/WO2003043636A1/en not_active Ceased
- 2002-11-11 CN CNB028228391A patent/CN100546580C/zh not_active Expired - Fee Related
- 2002-11-11 PT PT02787632T patent/PT1448198E/pt unknown
- 2002-11-11 HU HU0402161A patent/HUP0402161A3/hu not_active Application Discontinuation
- 2002-11-14 PA PA20028558001A patent/PA8558001A1/es unknown
- 2002-11-14 TW TW091133371A patent/TW200407134A/zh unknown
- 2002-11-15 PE PE2002001104A patent/PE20030713A1/es not_active Application Discontinuation
- 2002-11-18 MY MYPI20024303A patent/MY126176A/en unknown
- 2002-11-18 UY UY27542A patent/UY27542A1/es not_active Application Discontinuation
- 2002-11-18 GT GT200200232A patent/GT200200232A/es unknown
- 2002-11-18 AR ARP020104416A patent/AR039367A1/es unknown
- 2002-11-18 JO JO2002114A patent/JO2290B1/en active
2004
- 2004-04-26 IL IL161623A patent/IL161623A/en not_active IP Right Cessation
- 2004-05-17 EC EC2004005109A patent/ECSP045109A/es unknown
- 2004-05-18 ZA ZA200403817A patent/ZA200403817B/en unknown
- 2004-05-18 TN TNP2004000087A patent/TNSN04087A1/en unknown
- 2004-05-18 MA MA27681A patent/MA27083A1/fr unknown
- 2004-06-18 NO NO20042576A patent/NO20042576L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CN100546580C (zh)	2009-10-07
ES2294187T3 (es)	2008-04-01
ECSP045109A (es)	2004-06-28
US20030134854A1 (en)	2003-07-17
RS39904A (sr)	2006-10-27
PT1448198E (pt)	2007-12-11
JO2290B1 (en)	2005-09-12
JP2005522413A (ja)	2005-07-28
IL161623A0 (en)	2004-09-27
BR0214245A (pt)	2004-12-14
CN1617722A (zh)	2005-05-18
WO2003043636A1 (en)	2003-05-30
EP1448198B1 (en)	2007-10-31
ZA200403817B (en)	2005-05-23
AU2002351955A1 (en)	2003-06-10
HRP20040396A2 (en)	2005-04-30
IL161623A (en)	2010-11-30
RU2294933C2 (ru)	2007-03-10
GT200200232A (es)	2003-06-17
SI1448198T1 (sl)	2008-02-29
TNSN04087A1 (en)	2006-06-01
JP4226474B2 (ja)	2009-02-18
AU2002351955B2 (en)	2007-03-15
CA2467552C (en)	2011-05-24
DK1448198T3 (da)	2008-01-07
MY126176A (en)	2006-09-29
KR20050044535A (ko)	2005-05-12
NZ532802A (en)	2005-07-29
HUP0402161A3 (en)	2010-06-28
EA007502B1 (ru)	2006-10-27
MA27083A1 (fr)	2004-12-20
HUP0402161A2 (hu)	2005-02-28
DE60223278T2 (de)	2008-08-14
ATE376831T1 (de)	2007-11-15
UY27542A1 (es)	2003-05-30
EA200400598A1 (ru)	2005-02-24
CA2467552A1 (en)	2003-05-30
RU2004118425A (ru)	2006-01-10
US6620811B2 (en)	2003-09-16
MXPA04004684A (es)	2004-08-12
EP1448198A1 (en)	2004-08-25
DE60223278D1 (de)	2007-12-13
UA77462C2 (en)	2006-12-15
PA8558001A1 (es)	2003-07-28
KR100577110B1 (ko)	2006-05-10
PE20030713A1 (es)	2003-08-23
AR039367A1 (es)	2005-02-16
NO20042576L (no)	2004-06-18
PL369517A1 (en)	2005-04-18

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