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TR201816176T4 - Histon deasetilaz 6 inhibitörleri olarak yeni bileşikler ve bunu içeren farmasötik bileşimler. - Google Patents

Histon deasetilaz 6 inhibitörleri olarak yeni bileşikler ve bunu içeren farmasötik bileşimler. Download PDF

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Publication number
TR201816176T4
TR201816176T4 TR2018/16176T TR201816176T TR201816176T4 TR 201816176 T4 TR201816176 T4 TR 201816176T4 TR 2018/16176 T TR2018/16176 T TR 2018/16176T TR 201816176 T TR201816176 T TR 201816176T TR 201816176 T4 TR201816176 T4 TR 201816176T4
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Turkey
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novel compounds
histone deacetylase
pharmaceutical compositions
compositions containing
same
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TR2018/16176T
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English (en)
Inventor
Song Hyeseung
Lee Changgon
Kwak Dalyong
Lee Jaeyoung
Bae Suyeal
Kim Yuntae
Bae Daekwon
Ha Nina
BAE Miseon
Kim Jihyun
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Chong Kun Dang Pharmaceutical Corp
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Publication of TR201816176T4 publication Critical patent/TR201816176T4/tr

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    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
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Abstract

Mevcut buluş histon deasetilaz 6 (HDAC6) inhibitör aktivitesine sahip yeni bileşikler, bunun izomerleri veya bunun farmasötik olarak kabul edilebilir tuzları, terapötik tıbbi ilaçların hazırlanışına yönelik bunun kullanımı, bunu içeren farmasötik bileşimler, bileşim kullanılarak hastalık tedavi edilmesinin bir yöntemi ve yeni bileşiklerin hazırlanmasına yönelik yöntemler ile ilgilidir. Mevcut buluşa göre yeni bileşikler histon deasetilaz 6 (HDAC6) inhibitör aktivitesine sahiptir ve kanser, inflamatuar hastalıklar, otoimmün hastalıklar, nörolojik hastalıklar ve nörodejeneratif bozukluklar dahil HDAC6-ilişkili hastalıkların önlenmesi veya tedavisine yönelik etkilidir.
TR2018/16176T 2014-03-12 2015-03-12 Histon deasetilaz 6 inhibitörleri olarak yeni bileşikler ve bunu içeren farmasötik bileşimler. TR201816176T4 (tr)

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KR20140028920 2014-03-12

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US (1) US10287255B2 (tr)
EP (1) EP3116859B1 (tr)
JP (1) JP6392888B2 (tr)
KR (1) KR101697518B1 (tr)
CN (1) CN106232584B (tr)
AU (1) AU2015230127B2 (tr)
CA (1) CA2941581C (tr)
DK (1) DK3116859T3 (tr)
ES (1) ES2694053T3 (tr)
HR (1) HRP20181534T1 (tr)
MX (1) MX2016011833A (tr)
MY (1) MY177631A (tr)
NZ (1) NZ724030A (tr)
PH (1) PH12016501735B1 (tr)
PL (1) PL3116859T3 (tr)
PT (1) PT3116859T (tr)
RU (1) RU2660897C2 (tr)
TR (1) TR201816176T4 (tr)
WO (1) WO2015137750A1 (tr)

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WO2015137750A1 (en) 2015-09-17
KR20150106857A (ko) 2015-09-22
US20170096405A1 (en) 2017-04-06
PH12016501735B1 (en) 2019-05-31
DK3116859T3 (en) 2018-11-26
ES2694053T3 (es) 2018-12-17
PH12016501735A1 (en) 2017-02-06
CA2941581C (en) 2018-07-24
PT3116859T (pt) 2018-11-15
RU2660897C2 (ru) 2018-07-11
JP6392888B2 (ja) 2018-09-19
CN106232584A (zh) 2016-12-14
MX2016011833A (es) 2017-03-29
EP3116859A4 (en) 2017-02-08
HRP20181534T1 (hr) 2019-01-11
KR101697518B1 (ko) 2017-01-19
EP3116859B1 (en) 2018-08-01
AU2015230127A1 (en) 2016-09-22
CN106232584B (zh) 2019-06-28
PL3116859T3 (pl) 2019-04-30
EP3116859A1 (en) 2017-01-18
MY177631A (en) 2020-09-23
RU2016139690A (ru) 2018-04-16
JP2017507976A (ja) 2017-03-23
CA2941581A1 (en) 2015-09-17
NZ724030A (en) 2017-09-29
US10287255B2 (en) 2019-05-14
AU2015230127B2 (en) 2017-04-20

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