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TR200800474T2 - Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem. - Google Patents

Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem.

Info

Publication number
TR200800474T2
TR200800474T2 TR2008/00474T TR200800474T TR200800474T2 TR 200800474 T2 TR200800474 T2 TR 200800474T2 TR 2008/00474 T TR2008/00474 T TR 2008/00474T TR 200800474 T TR200800474 T TR 200800474T TR 200800474 T2 TR200800474 T2 TR 200800474T2
Authority
TR
Turkey
Prior art keywords
preparation
intermediates
fluorfenicol
formula
florphenicol
Prior art date
Application number
TR2008/00474T
Other languages
English (en)
Inventor
B. Vashi Dhiru
C. Towson James
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24808601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200800474(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of TR200800474T2 publication Critical patent/TR200800474T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

R ve R"' in burada belirtildiği şekilde olduğu formül (I)'in bileşiğinin hazırlanmasına yönelik bir işlem. Formül (I)' in bileşikleri, florfenikolün hazırlanmasında aracı maddeler olarak yararlıdır.
TR2008/00474T 1996-08-19 1997-08-18 Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem. TR200800474T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/699,271 US5663361A (en) 1996-08-19 1996-08-19 Process for preparing intermediates to florfenicol

Publications (1)

Publication Number Publication Date
TR200800474T2 true TR200800474T2 (tr) 2008-04-21

Family

ID=24808601

Family Applications (2)

Application Number Title Priority Date Filing Date
TR1999/00354T TR199900354T2 (tr) 1996-08-19 1997-08-18 Florfenikole araci maddelerin hazirlanmasina iliskin islem.
TR2008/00474T TR200800474T2 (tr) 1996-08-19 1997-08-18 Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TR1999/00354T TR199900354T2 (tr) 1996-08-19 1997-08-18 Florfenikole araci maddelerin hazirlanmasina iliskin islem.

Country Status (30)

Country Link
US (1) US5663361A (tr)
EP (1) EP0922040B2 (tr)
JP (1) JP3274868B2 (tr)
KR (1) KR100286851B1 (tr)
CN (1) CN1097583C (tr)
AR (1) AR008298A1 (tr)
AT (1) ATE283847T1 (tr)
AU (1) AU714495B2 (tr)
BR (1) BR9711318B1 (tr)
CA (1) CA2264116C (tr)
CO (1) CO4560550A1 (tr)
CZ (1) CZ297915B6 (tr)
DE (1) DE69731835T3 (tr)
DK (1) DK0922040T3 (tr)
ES (1) ES2234026T5 (tr)
HU (1) HU229610B1 (tr)
ID (1) ID18047A (tr)
IL (1) IL128574A (tr)
MY (1) MY115679A (tr)
NO (1) NO312962B1 (tr)
NZ (1) NZ334111A (tr)
PE (1) PE99798A1 (tr)
PL (2) PL198553B1 (tr)
PT (1) PT922040E (tr)
SI (1) SI0922040T1 (tr)
SK (1) SK286124B6 (tr)
TR (2) TR199900354T2 (tr)
TW (1) TW381075B (tr)
WO (1) WO1998007709A1 (tr)
ZA (1) ZA977406B (tr)

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BR0308289A (pt) * 2002-03-08 2005-01-11 Schering Plough Ltd Antibióticos do tipo florfenicol
AR044437A1 (es) * 2003-05-29 2005-09-14 Schering Plough Ltd Composiciones y metodo para el tratamiento de infecciones en ganado vacuno y porcino
US7439268B2 (en) 2003-07-18 2008-10-21 Idexx Laboratories Compositions containing prodrugs of florfenicol and methods of use
US20050049210A1 (en) * 2003-08-27 2005-03-03 Idexx Laboratories, Inc. Methods for the controlled delivery of pharmacologically active compounds
US7126005B2 (en) * 2003-10-06 2006-10-24 Aurobindo Pharma Limited Process for preparing florfenicol
BRPI0514098B1 (pt) * 2004-08-13 2021-01-19 Intervet International B. V. composição farmacêutica tópica para o tratamento de uma infecção ótica
CA2580843C (en) 2004-09-23 2011-03-29 Schering-Plough Ltd. Control of parasites in animals by the use of trifluoromethanesulfonanilide oxime ether derivatives
US7705038B2 (en) * 2004-11-19 2010-04-27 Intervet, Inc. Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives
JP5017122B2 (ja) * 2004-12-21 2012-09-05 インターベツト・インターナシヨナル・ベー・ベー 注射可能な獣医学組成物
AR054380A1 (es) * 2005-06-09 2007-06-20 Schering Plough Ltd Control de parasitos en animales con derivados de n- ((feniloxi) fenil) -1,1,1-trifluorometansulfonamida y de n-(fenilsulfanil) fenil) -1,1,1-trifluorometansulfonamida
KR20080049039A (ko) * 2005-09-07 2008-06-03 쉐링-프라우 리미티드 플로르페니콜에 대한 중간체로서 유용한 옥사졸리딘 보호된아미노디올 화합물의 제조방법
US8119667B2 (en) * 2005-12-29 2012-02-21 Schering-Plough Animal Health Corporation Carbonates of fenicol antibiotics
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
US20070238700A1 (en) * 2006-04-10 2007-10-11 Winzenberg Kevin N N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
EP2102154A1 (en) * 2006-12-13 2009-09-23 Schering-Plough Ltd. Water-soluble prodrugs of chloramphenicol, thiamphenicol, and analogs thereof
EP2091909A1 (en) * 2006-12-13 2009-08-26 Schering-Plough Ltd. Water-soluble prodrugs of florfenicol and its analogs
KR20100028537A (ko) * 2007-04-27 2010-03-12 쉐링-프라우 리미티드 사이클로덱스트린을 사용하여 플로르페니콜 및 구조적으로 관련된 항생제의 용해도를 증진시키기 위한 화합물 및 방법
AR066748A1 (es) * 2007-05-30 2009-09-09 Schering Plough Ltd Un proceso para la preparacion de compuestos de aminodiol protegidos con oxazolina utiles como intemediarios para florfenicol
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
KR101769728B1 (ko) 2007-06-27 2017-08-18 이 아이 듀폰 디 네모아 앤드 캄파니 동물 해충 방제 방법
BRPI0814581A2 (pt) * 2007-07-25 2017-05-09 Intervet Int Bv processo para a preparação de um composto, e, composto.
US7550625B2 (en) * 2007-10-19 2009-06-23 Idexx Laboratories Esters of florfenicol
WO2009061780A1 (en) * 2007-11-09 2009-05-14 Schering-Plough Limited Fast release solid formulation, preparation and use thereof
TWI468407B (zh) 2008-02-06 2015-01-11 Du Pont 中離子農藥
KR20110038723A (ko) * 2008-07-30 2011-04-14 인터벳 인터내셔널 비.브이. 플로르페니콜에 대한 중간체로서 유용한 옥사졸린-보호된 아미노디올 화합물의 제조 방법
KR20120047996A (ko) 2009-08-05 2012-05-14 이 아이 듀폰 디 네모아 앤드 캄파니 메소이온성 살충제
UA110924C2 (uk) 2009-08-05 2016-03-10 Е. І. Дю Пон Де Немур Енд Компані Мезоіонні пестициди
EP2461684A2 (en) 2009-08-05 2012-06-13 E. I. du Pont de Nemours and Company Mesoionic pesticides
UA107804C2 (en) 2009-08-05 2015-02-25 Du Pont Mixtures of pesticides mezoionnyh
BRPI1002023A2 (pt) 2010-03-01 2011-10-25 Nanocore Biotecnologia S A forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
PL2576523T3 (pl) 2010-05-27 2016-08-31 Du Pont Krystaliczna postać 4-[5 - [3 -chloro-5 -(trifluorometylo)fenylo] -4,5 -dihydro-5 -(trifluorometylo)-3 - izoksazolilo]-n-[2-okso-2-[(2,2,2-trifluoroetylo)amino]etylo]-1- naftalenokarboksyamidu
WO2012087630A1 (en) 2010-12-20 2012-06-28 E.I. Du Pont De Nemours And Company Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en) 2012-04-17 2013-10-24 E. I. Du Pont De Nemours And Company Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) * 2012-10-31 2014-07-02 绍兴民生医药有限公司 (4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103254147B (zh) * 2013-04-19 2016-04-06 浙江科技学院 一种d-苏式-2-(二氯甲基)-4,5-二氢-5-[对-（甲砜基）苯基]-4-噁唑甲醇的制备方法
CN106278964B (zh) * 2016-07-31 2018-01-16 浙江润康药业有限公司 氟苯尼考的制备方法
CN106631872A (zh) * 2016-12-13 2017-05-10 浙江普洛家园药业有限公司 一种氟苯尼考类似物中间体的合成方法
CN110272856B (zh) * 2019-05-08 2022-05-03 江南大学 一种表达d-苏氨酸醛缩酶的重组菌及其构建方法与应用
CN117466787B (zh) * 2023-12-28 2024-03-22 山东国邦药业有限公司 一种氟苯尼考中间体的制备方法

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US2759001A (en) * 1952-03-01 1956-08-14 Parke Davis & Co Process for the production of delta2-oxazolines
US4361557A (en) * 1980-01-28 1982-11-30 Schering Corporation 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor
EP0678506A3 (en) * 1983-06-02 1996-07-24 Zambon Spa Intermediates for the production of 1-phenyl-1-hydroxy-2-amino-3-fluoropropane derivatives.
US4876352A (en) * 1988-09-14 1989-10-24 Schering Corporation Pressurized fluorination of hydroxy alkyl groups
AU5674690A (en) † 1989-05-15 1990-12-18 Schering Corporation Process for preparing antibacterial compounds and intermediates thereto
DE69105752T2 (de) * 1990-10-25 1995-05-11 Schering Corp., Kenilworth, N.J. Verfahren zur herstellung von florfenicol, seine analoga und oxazolinzwischenprodukte.

Also Published As

Publication number Publication date
ID18047A (id) 1998-02-19
EP0922040B1 (en) 2004-12-01
TW381075B (en) 2000-02-01
SI0922040T1 (en) 2005-02-28
IL128574A (en) 2002-04-21
CO4560550A1 (es) 1998-02-10
CN1097583C (zh) 2003-01-01
JP3274868B2 (ja) 2002-04-15
NO990756D0 (no) 1999-02-18
PL196454B1 (pl) 2008-01-31
DE69731835T2 (de) 2005-07-21
WO1998007709A1 (en) 1998-02-26
PE99798A1 (es) 1998-12-28
CZ297915B6 (cs) 2007-04-25
AR008298A1 (es) 1999-12-29
ZA977406B (en) 1998-02-18
HUP9904166A3 (en) 2001-11-28
CA2264116A1 (en) 1998-02-26
ES2234026T5 (es) 2013-11-12
CA2264116C (en) 2002-07-02
PL331644A1 (en) 1999-08-02
AU4063897A (en) 1998-03-06
DK0922040T3 (da) 2005-04-04
KR100286851B1 (ko) 2001-04-16
MY115679A (en) 2003-08-30
NZ334111A (en) 1999-10-28
EP0922040B2 (en) 2013-07-17
US5663361A (en) 1997-09-02
KR20000068178A (ko) 2000-11-25
IL128574A0 (en) 2000-01-31
BR9711318A (pt) 1999-08-17
HK1017890A1 (en) 1999-12-03
TR199900354T2 (tr) 1999-05-21
PT922040E (pt) 2005-02-28
NO990756L (no) 1999-02-18
ATE283847T1 (de) 2004-12-15
CZ54099A3 (cs) 1999-07-14
DE69731835D1 (de) 2005-01-05
CN1233244A (zh) 1999-10-27
SK19999A3 (en) 2000-02-14
ES2234026T3 (es) 2005-06-16
DE69731835T3 (de) 2013-12-05
EP0922040A1 (en) 1999-06-16
HUP9904166A2 (hu) 2000-05-28
JP2000501424A (ja) 2000-02-08
AU714495B2 (en) 2000-01-06
NO312962B1 (no) 2002-07-22
SK286124B6 (sk) 2008-04-07
HU229610B1 (en) 2014-03-28
PL198553B1 (pl) 2008-06-30
BR9711318B1 (pt) 2009-01-13

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