[go: up one dir, main page]

TR200200460T2 - Yeni fenilpiperazinler - Google Patents

Yeni fenilpiperazinler

Info

Publication number
TR200200460T2
TR200200460T2 TR2002/00460T TR200200460T TR200200460T2 TR 200200460 T2 TR200200460 T2 TR 200200460T2 TR 2002/00460 T TR2002/00460 T TR 2002/00460T TR 200200460 T TR200200460 T TR 200200460T TR 200200460 T2 TR200200460 T2 TR 200200460T2
Authority
TR
Turkey
Prior art keywords
phenylpiperazines
new
new phenylpiperazines
relates
pharmacological properties
Prior art date
Application number
TR2002/00460T
Other languages
English (en)
Inventor
Van Hes Roelof
A.M. Van Der Heijden Johannes
G. Kruse Cornelis
Tipker Jacobus
T.M. Tulp Martinus
M. Visser Gerben
J. Van Vliet Bernard
Original Assignee
Solvay Pharmaceuticals B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals B.V. filed Critical Solvay Pharmaceuticals B.V.
Publication of TR200200460T2 publication Critical patent/TR200200460T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Bulus, dikkate deger farmakolojik vasiflara sahip yeni bir fenilpiperazinlerin grubuna iliskindir.
TR2002/00460T 1999-08-23 2000-08-22 Yeni fenilpiperazinler TR200200460T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202710 1999-08-23
NL1012888 1999-08-23

Publications (1)

Publication Number Publication Date
TR200200460T2 true TR200200460T2 (tr) 2002-06-21

Family

ID=26153354

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00460T TR200200460T2 (tr) 1999-08-23 2000-08-22 Yeni fenilpiperazinler

Country Status (29)

Country Link
US (3) US7067513B1 (tr)
EP (1) EP1212320B1 (tr)
JP (1) JP4919565B2 (tr)
KR (1) KR100634039B1 (tr)
CN (1) CN1155596C (tr)
AR (1) AR031526A1 (tr)
AT (1) ATE299142T1 (tr)
AU (1) AU772189B2 (tr)
BR (1) BR0013498A (tr)
CA (1) CA2379021C (tr)
CZ (1) CZ298533B6 (tr)
DE (1) DE60021194T2 (tr)
DK (1) DK1212320T3 (tr)
ES (1) ES2244469T3 (tr)
HU (1) HUP0203194A3 (tr)
IL (2) IL148218A0 (tr)
MX (1) MXPA02001919A (tr)
NO (1) NO321887B1 (tr)
NZ (1) NZ517900A (tr)
PL (1) PL201178B1 (tr)
PT (1) PT1212320E (tr)
RU (1) RU2246494C2 (tr)
SI (1) SI1212320T1 (tr)
SK (1) SK287018B6 (tr)
TR (1) TR200200460T2 (tr)
TW (1) TWI286136B (tr)
UA (1) UA74160C2 (tr)
WO (1) WO2001014330A2 (tr)
ZA (1) ZA200201829B (tr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0203194A3 (en) 1999-08-23 2004-01-28 Solvay Pharm Bv Phenylpiperazines, pharmaceutical compositions containing them and their use
AR032711A1 (es) 2001-02-21 2003-11-19 Solvay Pharm Bv Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene
AR032712A1 (es) * 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
WO2002085896A1 (en) * 2001-04-24 2002-10-31 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan
US7041683B2 (en) 2001-04-24 2006-05-09 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan
US6656950B2 (en) 2001-04-25 2003-12-02 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine
EP1408976B3 (en) 2001-07-20 2010-08-25 Psychogenics Inc. Treatment for attention-deficit hyperactivity disorder
EP1336406A1 (en) * 2002-02-14 2003-08-20 Solvay Pharmaceuticals B.V. Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity
NZ536230A (en) * 2002-05-13 2007-05-31 Hoffmann La Roche Benzoxazine derivatives as 5-hydroxytryptamine-6 (5-HT6) modulatory neurotransmitter in the brain
DE10233500A1 (de) * 2002-07-24 2004-02-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel
WO2004041792A1 (en) 2002-11-08 2004-05-21 F. Hoffmann-La Roche Ag Substituted benzoxazinones and uses thereof
US7276603B2 (en) * 2003-05-02 2007-10-02 Wyeth Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use
WO2004108671A1 (en) * 2003-06-06 2004-12-16 Suven Life Sciences Limited Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them
AR052332A1 (es) * 2004-12-07 2007-03-14 Solvay Pharm Bv Derivados de benzdioxanpiperazina con una afinidad combinada para receptores de dopamina-d2 y sitios de reabsorcion de serotonina, composiciones farmaceuticas que los contienen y su empleo como medicamentos para el tratamiento de enfermedades del snc
TW200633987A (en) * 2004-12-07 2006-10-01 Solvay Pharm Bv Phenylpiperazines with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites
US7371769B2 (en) 2004-12-07 2008-05-13 Solvay Pharmaceuticals B.V. Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites
US20060122247A1 (en) 2004-12-08 2006-06-08 Solvay Pharmaceuticals B.V. Aryloxyethylamine and phenylpiperazine derivatives with a combination of partial dopamine-D2 receptor agonism and serotonin reuptake inhibition
PT1824479E (pt) * 2004-12-08 2009-01-30 Solvay Pharm Bv Derivados de fenilpiperazina com uma combinação de agonismo de receptor de dopamina d2 parcial e inibição da reabsorção de serotonina
PE20070523A1 (es) 2005-09-12 2007-06-28 Wyeth Corp Formulacion de liberacion sostenida del glucuronato de (8-{4-[3-(5-fluoro-1h-indol-3-il)-propil]-piperazin-1-il}-2-metil-4h-benzo[1,4]oxazin-3-ona
GT200600414A (es) * 2005-09-12 2007-09-20 Sal de glucuranato de compuesto de piperazine
GT200600416A (es) 2005-09-12 2007-09-20 Sales salicilato y gentisato de un compuesto de piperazina
US9066903B2 (en) 2006-02-28 2015-06-30 The United States Of America As Represented By The Department Of Veterans Affairs Pharmacological treatment of Parkinson's disease
FR2941946B1 (fr) * 2009-02-12 2011-03-25 Sanofi Aventis Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique
JP5732453B2 (ja) * 2009-06-25 2015-06-10 アルカーメス ファーマ アイルランド リミテッド Ｎｈ酸性化合物のプロドラッグ
WO2015014256A1 (en) 2013-07-29 2015-02-05 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
US10316025B2 (en) 2015-06-03 2019-06-11 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use and use thereof

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1075156A (en) 1963-08-27 1967-07-12 Luso Farmaco Inst Substituted piperazines
GB8830312D0 (en) 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
DE4127849A1 (de) * 1991-08-22 1993-02-25 Merck Patent Gmbh Benzodioxanderivate
US5314896A (en) 1991-11-20 1994-05-24 Warner-Lambert Company 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents
DE4333254A1 (de) * 1993-09-30 1995-04-06 Merck Patent Gmbh Piperidine und Piperazine
DE4414113A1 (de) 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
US5576321A (en) 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
AR004229A1 (es) 1995-11-06 1998-11-04 Wyeth Corp Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
DE19730989A1 (de) * 1997-07-18 1999-01-21 Merck Patent Gmbh Piperazin-Derivate
ATE252575T1 (de) * 1997-07-25 2003-11-15 Lundbeck & Co As H Indole und 2,3-dihydroindolderivate, ihre herstellung und verwendung
ATE253058T1 (de) * 1997-09-02 2003-11-15 Duphar Int Res Piperidin- und piperazin derivate als 5-ht1- rezeptor-agonisten
EP0900792B1 (en) 1997-09-02 2003-10-29 Duphar International Research B.V Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists
ID27976A (id) * 1998-06-19 2001-05-03 Lundbeck & Co As H 4,5,6 dan 7-indol dan turunan-turunan indolin, pembuatan dan penggunaannya
EP1089997A1 (en) * 1998-06-19 2001-04-11 H.Lundbeck A/S 4,5,6 and 7-indole and indoline derivatives, their preparation and use
AR020773A1 (es) 1998-10-16 2002-05-29 Duphar Int Res Compuesto derivados de 3-(tetrahidropiridin-4-il)indol, metodo para prepararlo, una composicion farmaceutica que los contiene, metodo para preparar dicha composicion y uso del compuesto
AR022303A1 (es) * 1999-01-22 2002-09-04 Lundbeck & Co As H Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion
HUP0203194A3 (en) 1999-08-23 2004-01-28 Solvay Pharm Bv Phenylpiperazines, pharmaceutical compositions containing them and their use
AR032711A1 (es) 2001-02-21 2003-11-19 Solvay Pharm Bv Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene
AR032712A1 (es) * 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
EP1336406A1 (en) 2002-02-14 2003-08-20 Solvay Pharmaceuticals B.V. Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity

Also Published As

Publication number Publication date
PT1212320E (pt) 2005-11-30
NO20020810D0 (no) 2002-02-19
PL201178B1 (pl) 2009-03-31
SK2492002A3 (en) 2002-09-10
AR031526A1 (es) 2003-09-24
HK1051199A1 (en) 2003-07-25
US7605162B2 (en) 2009-10-20
DE60021194D1 (de) 2005-08-11
CA2379021A1 (en) 2001-03-01
CN1390214A (zh) 2003-01-08
IL148218A0 (en) 2002-09-12
AU7411800A (en) 2001-03-19
ATE299142T1 (de) 2005-07-15
JP4919565B2 (ja) 2012-04-18
US7456182B2 (en) 2008-11-25
DE60021194T2 (de) 2005-12-22
JP2003507454A (ja) 2003-02-25
DK1212320T3 (da) 2005-08-08
HUP0203194A3 (en) 2004-01-28
RU2246494C2 (ru) 2005-02-20
WO2001014330A2 (en) 2001-03-01
NZ517900A (en) 2003-08-29
US7067513B1 (en) 2006-06-27
UA74160C2 (uk) 2005-11-15
CN1155596C (zh) 2004-06-30
SI1212320T1 (en) 2005-10-31
KR100634039B1 (ko) 2006-10-17
IL148218A (en) 2007-05-15
SK287018B6 (sk) 2009-09-07
TWI286136B (en) 2007-09-01
PL364821A1 (en) 2004-12-13
US20060293313A1 (en) 2006-12-28
WO2001014330A3 (en) 2001-08-02
BR0013498A (pt) 2002-05-14
CZ298533B6 (cs) 2007-10-31
HUP0203194A2 (hu) 2003-01-28
US20090143406A1 (en) 2009-06-04
CA2379021C (en) 2009-10-27
ZA200201829B (en) 2003-08-27
MXPA02001919A (es) 2003-07-21
AU772189B2 (en) 2004-04-08
CZ2002619A3 (cs) 2002-08-14
NO20020810L (no) 2002-02-19
NO321887B1 (no) 2006-07-17
ES2244469T3 (es) 2005-12-16
KR20020057949A (ko) 2002-07-12
EP1212320A2 (en) 2002-06-12
EP1212320B1 (en) 2005-07-06

Similar Documents

Publication Publication Date Title
TR200200460T2 (tr) Yeni fenilpiperazinler
TR199701146T1 (tr) Nörotensin reseptörleri üzerinde etkili 1-Fenilpirazol-3-Karboksamidler.
TR200102800T2 (tr) Yeni bileşikler.
LU93311I2 (fr) Mancozèbe, valifenalate
BR0115400A (pt) Compostos de piperazinilpirazina atuando como agonistas ou antagonistas do receptor 5ht-2 de serotonina
DE69934345D1 (de) Selbstfüllender, nadelfreier Y-Adapter
BR0115436A (pt) Compostos de piperazinilpirazina atuando como antagonistas do receptor 5ht-2 de serotonina
TR970073A2 (tr) Alfa adrenerjik resentör antagonistleri olarak pirimidindion pirimidintrion,triazindion, tetrahidrokinazolindion türevleri.
EE200000577A (et) Elektronpääsmete või nendega seotud täiustused
TR200001472T2 (tr) 8-metoksi-kuinolon-karboksilik asitlerin hazırlanması için yöntem
DE69901941D1 (de) Heterogene, metallfasern enthaltende, strickwaren
TR199801866A1 (tr) Yeni piperazin ve piperidin bilesikleri
TR200003390T2 (tr) 2-(2-Metilfenil)-3,4-dihidro-2H-pirol türevleri
TR200003389T2 (tr) 2-(2-klorofenil)-3,4-dihidro-2H-pirol türevleri.
MY134008A (en) Subtituted 8-arylquinoline phospohodiestrase-4 inhibitors
ID26184A (id) Hidrogenase alfa, omega-dinitril alifatik
DE69902811D1 (de) Selbstheilende, gegenüber starken oxidationsmitteln beständige gegenstände
MEP36808A (en) Ambroxol-containing lozenge
EA200100854A1 (ru) Кальций-литические соединения
TR200200357T2 (tr) Yeni integrin reseptör antagonistleri
BR0115996A (pt) Sulfamidotienopirimidinas
DK1204659T3 (da) Serotonerge benzofuraner
DE10085072T1 (de) Faserige, gekräuselte Textilerzeugnisse
ZA200107985B (en) Substituted benzimidazole, the production thereof and the use thereof as means against parasitic protozoa.
TR200003203T2 (tr) Karboksaldehitin saflaştırılması