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TR200200307T2 - Alfa-Kloroepoksi esterleri vasıtasıyla asit hazırlama prosesi - Google Patents

Alfa-Kloroepoksi esterleri vasıtasıyla asit hazırlama prosesi

Info

Publication number
TR200200307T2
TR200200307T2 TR2002/00307T TR200200307T TR200200307T2 TR 200200307 T2 TR200200307 T2 TR 200200307T2 TR 2002/00307 T TR2002/00307 T TR 2002/00307T TR 200200307 T TR200200307 T TR 200200307T TR 200200307 T2 TR200200307 T2 TR 200200307T2
Authority
TR
Turkey
Prior art keywords
chloroepoxy
alpha
esters
preparation process
acid preparation
Prior art date
Application number
TR2002/00307T
Other languages
English (en)
Inventor
M Diederich Ann
J.Novack Vance
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of TR200200307T2 publication Critical patent/TR200200307T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Bu bulus, bir kloroepoksi esteri vasitasiyla, fosfodiesteraz 4 inhibitörleri olarak kullanilabilecek bazi formül (I) asitlerinin hazirlanmasi için bir yöntemle ilgilidir.
TR2002/00307T 1999-08-06 2000-08-04 Alfa-Kloroepoksi esterleri vasıtasıyla asit hazırlama prosesi TR200200307T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14757699P 1999-08-06 1999-08-06

Publications (1)

Publication Number Publication Date
TR200200307T2 true TR200200307T2 (tr) 2002-05-21

Family

ID=22522121

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/00307T TR200200307T2 (tr) 1999-08-06 2000-08-04 Alfa-Kloroepoksi esterleri vasıtasıyla asit hazırlama prosesi

Country Status (26)

Country Link
EP (1) EP1200394B1 (tr)
JP (1) JP2003506431A (tr)
KR (1) KR20020022793A (tr)
CN (4) CN1530362A (tr)
AR (1) AR025028A1 (tr)
AT (1) ATE340780T1 (tr)
AU (1) AU774582B2 (tr)
BR (1) BR0013025A (tr)
CA (1) CA2381010A1 (tr)
CO (1) CO5190744A1 (tr)
CZ (1) CZ2002428A3 (tr)
DE (1) DE60030981T2 (tr)
EC (1) ECSP003599A (tr)
ES (1) ES2272310T3 (tr)
HK (1) HK1047080A1 (tr)
HU (1) HUP0202453A2 (tr)
IL (1) IL147365A0 (tr)
MX (1) MXPA02001337A (tr)
NO (1) NO20020561L (tr)
NZ (1) NZ516945A (tr)
PE (1) PE20010398A1 (tr)
PL (1) PL353347A1 (tr)
TR (1) TR200200307T2 (tr)
UY (1) UY26268A1 (tr)
WO (1) WO2001010822A1 (tr)
ZA (1) ZA200200965B (tr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101116828B (zh) * 2006-08-03 2011-06-01 中国科学院大连化学物理研究所 手性吡啶双噁唑啉催化剂及制备方法和应用
US10526287B2 (en) 2015-04-23 2020-01-07 Constellation Pharmaceuticals, Inc. LSD1 inhibitors and uses thereof
PT3532459T (pt) 2016-10-26 2023-11-10 Constellation Pharmaceuticals Inc Inibidores de lsd1 e seus usos médicos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3803593A (en) * 1992-04-02 1993-11-08 Smithkline Beecham Corporation Compounds
JP3251587B2 (ja) * 1992-04-02 2002-01-28 スミスクライン・ビーチャム・コーポレイション 炎症疾患の治療および腫瘍壊死因子の産生阻害に有用な化合物
MX9301903A (es) * 1992-04-02 1994-08-31 Smithkline Beecham Corp Compuestos.
HU225869B1 (en) * 1992-04-02 2007-11-28 Smithkline Beecham Corp Compounds with antiallergic and antiinflammatory activity and pharmaceutical compns. contg. them
GB9404706D0 (en) * 1994-03-11 1994-04-27 Smithkline Beecham Corp Compounds
AR012550A1 (es) * 1997-02-12 2000-11-08 Smithkline Beecham Corp Metodo para preparar acidos 4-fenil-4-ciano-ciclohexanoicos sustituidos y compuestos intermediarios

Also Published As

Publication number Publication date
ES2272310T3 (es) 2007-05-01
CN1266119C (zh) 2006-07-26
WO2001010822A1 (en) 2001-02-15
EP1200394B1 (en) 2006-09-27
PE20010398A1 (es) 2001-06-14
EP1200394A1 (en) 2002-05-02
CN1368955A (zh) 2002-09-11
CN1597675A (zh) 2005-03-23
JP2003506431A (ja) 2003-02-18
CA2381010A1 (en) 2001-02-15
KR20020022793A (ko) 2002-03-27
CZ2002428A3 (cs) 2002-06-12
NZ516945A (en) 2004-01-30
NO20020561D0 (no) 2002-02-05
ZA200200965B (en) 2003-04-30
CN1217923C (zh) 2005-09-07
PL353347A1 (en) 2003-11-17
BR0013025A (pt) 2002-04-16
CN1530360A (zh) 2004-09-22
HUP0202453A2 (en) 2002-10-28
AU6622200A (en) 2001-03-05
NO20020561L (no) 2002-02-05
UY26268A1 (es) 2001-01-31
AR025028A1 (es) 2002-11-06
EP1200394A4 (en) 2004-12-01
CN1530362A (zh) 2004-09-22
AU774582B2 (en) 2004-07-01
DE60030981T2 (de) 2007-09-06
ATE340780T1 (de) 2006-10-15
DE60030981D1 (de) 2006-11-09
IL147365A0 (en) 2002-08-14
ECSP003599A (es) 2002-03-25
MXPA02001337A (es) 2002-07-22
CO5190744A1 (es) 2002-08-29
HK1047080A1 (zh) 2003-02-07

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