TR200200198T2 - Düşük dozlu tabletler ve hazırlama yöntemi - Google Patents
Düşük dozlu tabletler ve hazırlama yöntemiInfo
- Publication number
- TR200200198T2 TR200200198T2 TR2002/00198T TR200200198T TR200200198T2 TR 200200198 T2 TR200200198 T2 TR 200200198T2 TR 2002/00198 T TR2002/00198 T TR 2002/00198T TR 200200198 T TR200200198 T TR 200200198T TR 200200198 T2 TR200200198 T2 TR 200200198T2
- Authority
- TR
- Turkey
- Prior art keywords
- preparation
- low
- dose tablets
- release
- micro granules
- Prior art date
Links
- 239000003085 diluting agent Substances 0.000 abstract 2
- 239000008187 granular material Substances 0.000 abstract 2
- 230000007935 neutral effect Effects 0.000 abstract 2
- 239000013589 supplement Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bulus, dogrudan sikistirilabilir bir sulandiriciyi içinde bulunduran aktif tamamlayici maddenin düsük bir dozunu ihtiva eden mikro granüllü bir tabletle ilgilidir. Bulusun özelligi, dogrudan sikistirilabilir sulandiricinin sadece nötr haldeki mikro granüllerden ibaret olmasi, ve aktif tamamlayici maddenin nötr haldeki mikro granüllerin üzerine yerlestirilmesi ve bunun saliverilmesini degistirmek ya da tadini gizlemek üzere dizayn edilmis bir madde ile kaplanmamasidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9909653A FR2796840B1 (fr) | 1999-07-26 | 1999-07-26 | Comprimes faiblement doses et procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200200198T2 true TR200200198T2 (tr) | 2002-09-23 |
Family
ID=9548499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/00198T TR200200198T2 (tr) | 1999-07-26 | 2000-07-25 | Düşük dozlu tabletler ve hazırlama yöntemi |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US8337892B1 (tr) |
| EP (1) | EP1200071B1 (tr) |
| JP (1) | JP4812211B2 (tr) |
| KR (1) | KR100649949B1 (tr) |
| CN (1) | CN1172660C (tr) |
| AT (1) | ATE236621T1 (tr) |
| AU (1) | AU774801B2 (tr) |
| BG (1) | BG65535B1 (tr) |
| BR (1) | BR0012775A (tr) |
| CA (1) | CA2391240C (tr) |
| CZ (1) | CZ300238B6 (tr) |
| DE (1) | DE60002089T2 (tr) |
| DK (1) | DK1200071T3 (tr) |
| DZ (1) | DZ3208A1 (tr) |
| ES (1) | ES2191638T3 (tr) |
| FR (1) | FR2796840B1 (tr) |
| HR (1) | HRP20020165B1 (tr) |
| HU (1) | HU228638B1 (tr) |
| IL (2) | IL147682A0 (tr) |
| MA (1) | MA25424A1 (tr) |
| MX (1) | MXPA02000922A (tr) |
| NO (1) | NO331905B1 (tr) |
| NZ (1) | NZ516726A (tr) |
| PL (1) | PL201215B1 (tr) |
| PT (1) | PT1200071E (tr) |
| SK (1) | SK285514B6 (tr) |
| TR (1) | TR200200198T2 (tr) |
| WO (1) | WO2001006982A2 (tr) |
| ZA (1) | ZA200200380B (tr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2852607B1 (fr) * | 2003-03-20 | 2006-07-14 | Procede de fabrication de microspheres de sucre de petite taille, les microspheres susceptibles d'etre obtenues par ce procede et leurs applications | |
| FR2861990B1 (fr) | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
| EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
| TR201819108T4 (tr) * | 2004-06-10 | 2019-01-21 | Glatt Air Techniques Inc | Kontrollü salımlı matrisli farmasötik dozaj formülasyonu. |
| FR2883179B1 (fr) | 2005-03-18 | 2009-04-17 | Ethypharm Sa | Comprime enrobe |
| US9795568B2 (en) | 2010-05-05 | 2017-10-24 | Boehringer Ingelheim Vetmedica Gmbh | Low concentration meloxicam tablets |
| FR2960775A1 (fr) | 2010-06-07 | 2011-12-09 | Ethypharm Sa | Microgranules resistants au detournement |
| CN102416003A (zh) * | 2011-12-08 | 2012-04-18 | 南京优科生物医药有限公司 | 一种制备恩替卡韦片剂的方法 |
| JP5897196B1 (ja) * | 2015-10-05 | 2016-03-30 | 大同化成工業株式会社 | 糖又は糖アルコール、膨潤型結合剤、崩壊剤及び高吸収性賦形剤を含む複合化造粒物及びその製造方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2996431A (en) * | 1953-12-16 | 1961-08-15 | Barry Richard Henry | Friable tablet and process for manufacturing same |
| US3568828A (en) * | 1967-03-01 | 1971-03-09 | Squibb & Sons Inc | Modified sequential oral contraceptive |
| US4634587A (en) * | 1982-07-09 | 1987-01-06 | Key Pharmaceuticals, Inc. | Sustained release quinidine dosage form |
| US4489026A (en) * | 1982-09-07 | 1984-12-18 | The Upjohn Company | Process for preparing solid unit dosage forms of ultra-low dose drugs |
| US4684516A (en) * | 1983-08-01 | 1987-08-04 | Alra Laboratories, Inc. | Sustained release tablets and method of making same |
| GB8414220D0 (en) * | 1984-06-04 | 1984-07-11 | Sterwin Ag | Medicaments in unit dose form |
| WO1988002629A1 (en) * | 1986-10-16 | 1988-04-21 | American Health Products Corporation | 2',3'-didesoxyadenosine composition |
| US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
| US4925674A (en) * | 1988-08-25 | 1990-05-15 | Himedics, Inc. | Amoxicillin microencapsulated granules |
| NZ230763A (en) * | 1988-09-27 | 1991-10-25 | Takeda Chemical Industries Ltd | Production of granules having a core by spraying the cores with a dispersion of hydroxypropylcellulose, optionally incorporating an active ingredient |
| US4966770A (en) * | 1989-07-26 | 1990-10-30 | Himedics, Inc. | Prednisone microencapsulated granules |
| US4983399A (en) * | 1989-10-18 | 1991-01-08 | Eastman Kodak Company | Direct compression carrier composition |
| JP2820829B2 (ja) * | 1991-03-07 | 1998-11-05 | 武田薬品工業株式会社 | 有核散剤およびその製造方法 |
| IE67345B1 (en) * | 1991-03-12 | 1996-03-20 | Akzo Nv | Low dose dry pharmaceutical preparations |
| AR004178A1 (es) * | 1995-07-29 | 1998-11-04 | Smithkline Beecham Plc | Procedimiento para la formulacion de un farmaco, una composicion farmaceutica obtenible mediante este procedimiento y el uso de la misma. |
| SE9600046D0 (sv) * | 1996-01-05 | 1996-01-05 | Astra Ab | New pharmaceutical formulation |
| GB9619074D0 (en) * | 1996-09-12 | 1996-10-23 | Smithkline Beecham Plc | Composition |
| FR2816507B1 (fr) * | 2000-11-16 | 2003-02-28 | Ethypharm Lab Prod Ethiques | Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules |
-
1999
- 1999-07-26 FR FR9909653A patent/FR2796840B1/fr not_active Expired - Lifetime
-
2000
- 2000-07-25 JP JP2001511874A patent/JP4812211B2/ja not_active Expired - Lifetime
- 2000-07-25 EP EP00958607A patent/EP1200071B1/fr not_active Expired - Lifetime
- 2000-07-25 AU AU70076/00A patent/AU774801B2/en not_active Expired
- 2000-07-25 CA CA2391240A patent/CA2391240C/fr not_active Expired - Lifetime
- 2000-07-25 IL IL14768200A patent/IL147682A0/xx active IP Right Grant
- 2000-07-25 BR BR0012775-2A patent/BR0012775A/pt not_active Application Discontinuation
- 2000-07-25 WO PCT/FR2000/002132 patent/WO2001006982A2/fr not_active Ceased
- 2000-07-25 PT PT00958607T patent/PT1200071E/pt unknown
- 2000-07-25 SK SK93-2002A patent/SK285514B6/sk not_active IP Right Cessation
- 2000-07-25 DK DK00958607T patent/DK1200071T3/da active
- 2000-07-25 CZ CZ20020179A patent/CZ300238B6/cs not_active IP Right Cessation
- 2000-07-25 MX MXPA02000922A patent/MXPA02000922A/es active IP Right Grant
- 2000-07-25 AT AT00958607T patent/ATE236621T1/de active
- 2000-07-25 TR TR2002/00198T patent/TR200200198T2/tr unknown
- 2000-07-25 NZ NZ516726A patent/NZ516726A/en not_active IP Right Cessation
- 2000-07-25 PL PL353134A patent/PL201215B1/pl unknown
- 2000-07-25 HR HR20020165A patent/HRP20020165B1/xx not_active IP Right Cessation
- 2000-07-25 HU HU0202228A patent/HU228638B1/hu not_active IP Right Cessation
- 2000-07-25 ES ES00958607T patent/ES2191638T3/es not_active Expired - Lifetime
- 2000-07-25 DE DE60002089T patent/DE60002089T2/de not_active Expired - Lifetime
- 2000-07-25 CN CNB008120978A patent/CN1172660C/zh not_active Expired - Lifetime
- 2000-07-25 KR KR1020027001128A patent/KR100649949B1/ko not_active Expired - Fee Related
- 2000-07-25 US US10/031,949 patent/US8337892B1/en not_active Expired - Fee Related
- 2000-07-25 DZ DZ003208A patent/DZ3208A1/xx active
-
2002
- 2002-01-16 NO NO20020243A patent/NO331905B1/no not_active IP Right Cessation
- 2002-01-16 ZA ZA200200380A patent/ZA200200380B/en unknown
- 2002-01-17 IL IL147682A patent/IL147682A/en unknown
- 2002-01-18 MA MA26491A patent/MA25424A1/fr unknown
- 2002-01-23 BG BG106342A patent/BG65535B1/bg unknown
-
2012
- 2012-08-16 US US13/587,629 patent/US20130039982A1/en not_active Abandoned
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