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TR200002214T2 - Omeprazolün midede bozunmayan mikro-zerreleri, üretim işlemleri ve farmasötik preparasyonlar. - Google Patents

Omeprazolün midede bozunmayan mikro-zerreleri, üretim işlemleri ve farmasötik preparasyonlar.

Info

Publication number
TR200002214T2
TR200002214T2 TR2000/02214T TR200002214T TR200002214T2 TR 200002214 T2 TR200002214 T2 TR 200002214T2 TR 2000/02214 T TR2000/02214 T TR 2000/02214T TR 200002214 T TR200002214 T TR 200002214T TR 200002214 T2 TR200002214 T2 TR 200002214T2
Authority
TR
Turkey
Prior art keywords
omeprazole
stomach
particles
pharmaceutical preparations
production processes
Prior art date
Application number
TR2000/02214T
Other languages
English (en)
Inventor
Debregeas Patrice
Leduc Gerard
Oury Pascal
Suplie Pascal
Original Assignee
Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9522415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200002214(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm filed Critical Ethypharm
Publication of TR200002214T2 publication Critical patent/TR200002214T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Bulus, her biri, aktif maddeyi ihtiva eden bir aktif tabakayi ve bir midede-bozunmayan maddeyi ihtiva eden bir dis midede-bozunmayan tabakayi içeren omeprazol mikrozerrelerine iliskindir, bulusun özelligi, omeprazolün, en azindan bir hidrofobik madde ile bir araya getirilmesidir.
TR2000/02214T 1998-01-30 1998-08-10 Omeprazolün midede bozunmayan mikro-zerreleri, üretim işlemleri ve farmasötik preparasyonlar. TR200002214T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9801098A FR2774288B1 (fr) 1998-01-30 1998-01-30 Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques

Publications (1)

Publication Number Publication Date
TR200002214T2 true TR200002214T2 (tr) 2000-12-21

Family

ID=9522415

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02214T TR200002214T2 (tr) 1998-01-30 1998-08-10 Omeprazolün midede bozunmayan mikro-zerreleri, üretim işlemleri ve farmasötik preparasyonlar.

Country Status (31)

Country Link
US (1) US6551621B1 (tr)
EP (1) EP1051174B2 (tr)
JP (1) JP4286452B2 (tr)
KR (1) KR100510366B1 (tr)
CN (1) CN1114405C (tr)
AT (1) ATE232100T1 (tr)
AU (1) AU755882B2 (tr)
BG (1) BG65087B1 (tr)
BR (1) BR9814924B1 (tr)
CA (1) CA2319015C (tr)
CZ (1) CZ299192B6 (tr)
DE (1) DE69811278T3 (tr)
DK (1) DK1051174T4 (tr)
EA (1) EA002879B1 (tr)
EE (1) EE05620B1 (tr)
ES (1) ES2189232T5 (tr)
FR (1) FR2774288B1 (tr)
GE (1) GEP20032941B (tr)
HU (1) HU229956B1 (tr)
IL (1) IL137536A0 (tr)
IS (1) IS2866B (tr)
NO (1) NO330144B1 (tr)
NZ (1) NZ505998A (tr)
PL (1) PL200043B1 (tr)
PT (1) PT1051174E (tr)
RS (1) RS50245B (tr)
SI (1) SI1051174T2 (tr)
SK (1) SK285666B6 (tr)
TR (1) TR200002214T2 (tr)
UA (1) UA61988C2 (tr)
WO (1) WO1999038511A1 (tr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
FR2793688B1 (fr) * 1999-05-21 2003-06-13 Ethypharm Lab Prod Ethiques Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
EP1603537A4 (en) * 2003-02-20 2009-11-04 Santarus Inc NOVEL FORMULATION, ANTICIPATED COMPLEX IMMEDIATE RELEASE FOR A FAST AND CONTINUOUS SUPPRESSION OF MAGIC ACID
ES2234393B2 (es) * 2003-04-29 2006-09-01 Laboratorios Belmac, S.A. "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido".
AR045062A1 (es) * 2003-07-18 2005-10-12 Santarus Inc Formulaciones farmaceuticas para inhibir la secrecion de acido y metodos para preparar y utilizarlas
TWI337877B (en) * 2003-07-18 2011-03-01 Santarus Inc Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CN1874764B (zh) * 2003-10-10 2012-08-01 埃法尔姆公司 含有银杏提取物的持续释放微粒及其制备方法
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US20050249806A1 (en) * 2004-02-10 2005-11-10 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and nonsteroidal anti-inflammatory drug
MXPA06011820A (es) * 2004-04-16 2006-12-15 Santarus Inc Combinacion de inhibidor de bomba de proton, agente regulador del ph y agente procinetico.
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
JP5563735B2 (ja) * 2004-06-16 2014-07-30 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド Ｐｐｉ多回剤形
EP1965774A2 (en) * 2005-12-30 2008-09-10 Cogentus Pharmaceuticals, Inc. Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors
JP5844028B2 (ja) 2006-04-04 2016-01-13 ケージー アクキュイシチオン エルエルシー 抗血小板薬及び酸阻害薬を含む経口剤形
AU2007266574A1 (en) * 2006-06-01 2007-12-06 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
WO2008047320A2 (en) * 2006-10-17 2008-04-24 Ranbaxy Laboratories Limited Multiple unit tablet compositions of benzimidazole compounds
CA2860231A1 (en) 2011-12-28 2013-07-04 Pozen Inc. Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US12472149B2 (en) 2015-07-17 2025-11-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
EP3117824A1 (en) 2015-07-17 2017-01-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
HRP20230250T1 (hr) 2015-07-17 2023-04-14 BE Pharbel Manufacturing Višeslojni farmaceutski aktivne mikročestice, koje otpuštaju spoj u tekućem obliku doziranja
US10736855B2 (en) 2016-02-25 2020-08-11 Dexcel Pharma Technologies Ltd. Compositions comprising proton pump inhibitors
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
FR3078630B1 (fr) 2018-03-08 2021-05-14 Karim Ioualalen Mode de formulation sous forme de solide divise hydrophobe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189698A (en) 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
JPH0768125B2 (ja) * 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
WO1996010624A1 (en) * 1994-09-30 1996-04-11 Medical Security Corporation Method and system for cleaning and slip-resistant treatment of surface coverings
ES2094694B1 (es) † 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
CH687810A5 (de) 1995-05-24 1997-02-28 Mepha Ag Pelletformulierung mit Omeprazol.
DK1308159T3 (da) * 1995-09-21 2005-02-14 Pharma Pass Ii Llc Farmaceutisk sammensætning indeholdende en syre-labil omeprazol og fremgangsmåde til fremstilling deraf
ZA979937B (en) * 1996-11-06 1999-05-18 Sharmatek Inc Delayed delivery system for acid-sensitive drugs
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
SE9704870D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I

Also Published As

Publication number Publication date
SK11412000A3 (sk) 2001-04-09
HUP0100347A3 (en) 2002-12-28
IS2866B (is) 2014-01-15
CZ299192B6 (cs) 2008-05-14
SI1051174T2 (sl) 2013-01-31
DK1051174T4 (da) 2012-10-01
WO1999038511A1 (fr) 1999-08-05
CN1284877A (zh) 2001-02-21
FR2774288B1 (fr) 2001-09-07
EP1051174B2 (fr) 2012-07-04
DE69811278T3 (de) 2012-11-29
BR9814924A (pt) 2000-10-17
EP1051174B1 (fr) 2003-02-05
PT1051174E (pt) 2003-06-30
NO20004654D0 (no) 2000-09-18
AU755882B2 (en) 2003-01-02
ES2189232T5 (es) 2012-11-07
DE69811278T2 (de) 2003-11-27
DE69811278D1 (de) 2003-03-13
HK1032354A1 (en) 2001-07-20
KR20010040502A (ko) 2001-05-15
CA2319015A1 (fr) 1999-08-05
AU9074898A (en) 1999-08-16
NO20004654L (no) 2000-09-18
EP1051174A1 (fr) 2000-11-15
EE200000466A (et) 2002-04-15
BR9814924B1 (pt) 2010-07-13
RS50245B (sr) 2009-07-15
UA61988C2 (uk) 2003-12-15
JP2002501895A (ja) 2002-01-22
HU229956B1 (hu) 2015-03-02
IS5577A (is) 2000-07-25
BG104634A (bg) 2001-02-28
FR2774288A1 (fr) 1999-08-06
DK1051174T3 (da) 2003-05-26
SI1051174T1 (sl) 2003-06-30
ES2189232T3 (es) 2003-07-01
KR100510366B1 (ko) 2005-08-24
EA002879B1 (ru) 2002-10-31
PL200043B1 (pl) 2008-11-28
IL137536A0 (en) 2001-07-24
CN1114405C (zh) 2003-07-16
NO330144B1 (no) 2011-02-21
SK285666B6 (sk) 2007-05-03
EA200000797A1 (ru) 2001-02-26
EE05620B1 (et) 2013-02-15
US6551621B1 (en) 2003-04-22
GEP20032941B (en) 2003-04-25
CA2319015C (fr) 2008-08-05
NZ505998A (en) 2003-11-28
YU48400A (sh) 2003-02-28
PL342044A1 (en) 2001-05-21
BG65087B1 (bg) 2007-02-28
HUP0100347A2 (hu) 2001-10-28
CZ20002709A3 (cs) 2000-12-13
JP4286452B2 (ja) 2009-07-01
ATE232100T1 (de) 2003-02-15

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