TR200102008T2 - Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı. - Google Patents
Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı.Info
- Publication number
- TR200102008T2 TR200102008T2 TR2001/02008T TR200102008T TR200102008T2 TR 200102008 T2 TR200102008 T2 TR 200102008T2 TR 2001/02008 T TR2001/02008 T TR 2001/02008T TR 200102008 T TR200102008 T TR 200102008T TR 200102008 T2 TR200102008 T2 TR 200102008T2
- Authority
- TR
- Turkey
- Prior art keywords
- treatment
- cerebral ischemia
- prophylaxis
- pyridine derivatives
- formula
- Prior art date
Links
- 201000006474 Brain Ischemia Diseases 0.000 title abstract 2
- 206010008120 Cerebral ischaemia Diseases 0.000 title abstract 2
- 206010008118 cerebral infarction Diseases 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 title 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bulus, ikame ajanlarinin açiklamada tanimlandigi gibi oldugu formül (I)'in pirimidin türevlerinin ve bunlarin fizyolojik olarak uygun tuzlarinin serebral iskeminin ve inmelerin önlenmesi ve tedavi edilmesi amaciyla ilaçlarin üretiminde kullanimi ile ilgilidir. (FORMÜL VAR)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19900545A DE19900545A1 (de) | 1999-01-11 | 1999-01-11 | Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200102008T2 true TR200102008T2 (tr) | 2001-12-21 |
Family
ID=7893836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2001/02008T TR200102008T2 (tr) | 1999-01-11 | 1999-12-24 | Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6387912B1 (tr) |
| EP (1) | EP1140096A1 (tr) |
| JP (1) | JP2002534465A (tr) |
| KR (1) | KR20010101442A (tr) |
| CN (1) | CN1334732A (tr) |
| AU (1) | AU2433800A (tr) |
| BG (1) | BG105689A (tr) |
| BR (1) | BR9916887A (tr) |
| CA (1) | CA2359253A1 (tr) |
| CZ (2) | CZ20012484A3 (tr) |
| DE (1) | DE19900545A1 (tr) |
| HK (1) | HK1042649A1 (tr) |
| HU (1) | HUP0201149A3 (tr) |
| ID (1) | ID30022A (tr) |
| IL (1) | IL144146A0 (tr) |
| MX (1) | MXPA01006967A (tr) |
| MY (1) | MY133107A (tr) |
| NO (1) | NO20013409L (tr) |
| NZ (1) | NZ512767A (tr) |
| PL (1) | PL348920A1 (tr) |
| SK (1) | SK9692001A3 (tr) |
| TR (1) | TR200102008T2 (tr) |
| WO (1) | WO2000041695A1 (tr) |
| ZA (1) | ZA200105475B (tr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19900673A1 (de) | 1999-01-11 | 2000-07-13 | Basf Ag | Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen |
| US6988199B2 (en) * | 2000-07-07 | 2006-01-17 | Message Secure | Secure and reliable document delivery |
| JP4548882B2 (ja) * | 1999-11-30 | 2010-09-22 | 興和創薬株式会社 | 4,5,6,7−テトラヒドロチエノ〔2,3−c〕ピリジン化合物 |
| DE10031389A1 (de) * | 2000-07-03 | 2002-01-17 | Knoll Ag | Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
| DE10031390A1 (de) * | 2000-07-03 | 2002-01-17 | Knoll Ag | Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
| DE10259382A1 (de) * | 2002-12-18 | 2004-07-01 | Abbott Gmbh & Co. Kg | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung |
| CA2685753A1 (en) * | 2007-05-09 | 2008-11-20 | Neuromed Pharmaceuticals Ltd. | Bicyclic pyrimidine derivatives as calcium channel blockers |
| US8927718B2 (en) | 2009-08-26 | 2015-01-06 | Takeda Pharmaceutical Company Limited | Fused heterocyclic ring derivative and use thereof |
| WO2021257857A1 (en) | 2020-06-19 | 2021-12-23 | Incyte Corporation | Naphthyridinone compounds as jak2 v617f inhibitors |
| US11753413B2 (en) | 2020-06-19 | 2023-09-12 | Incyte Corporation | Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors |
| CA3188639A1 (en) | 2020-07-02 | 2022-01-06 | Incyte Corporation | Tricyclic urea compounds as jak2 v617f inhibitors |
| WO2022006456A1 (en) | 2020-07-02 | 2022-01-06 | Incyte Corporation | Tricyclic pyridone compounds as jak2 v617f inhibitors |
| WO2022046989A1 (en) | 2020-08-27 | 2022-03-03 | Incyte Corporation | Tricyclic urea compounds as jak2 v617f inhibitors |
| US11919908B2 (en) | 2020-12-21 | 2024-03-05 | Incyte Corporation | Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors |
| EP4298099A1 (en) | 2021-02-25 | 2024-01-03 | Incyte Corporation | Spirocyclic lactams as jak2 v617f inhibitors |
| JP2025509672A (ja) | 2022-03-17 | 2025-04-11 | インサイト・コーポレイション | Jak2 v617f阻害剤としての三環式尿素化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4670560A (en) | 1986-04-28 | 1987-06-02 | Ortho Pharmaceutical Corporation | Thienopyrimidine-2,4-dione derivatives and intermediates thereof |
| DE19636769A1 (de) | 1996-09-10 | 1998-03-12 | Basf Ag | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724980A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724979A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
-
1999
- 1999-01-11 DE DE19900545A patent/DE19900545A1/de not_active Withdrawn
- 1999-12-22 ID IDW00200101717A patent/ID30022A/id unknown
- 1999-12-22 CZ CZ20012484A patent/CZ20012484A3/cs unknown
- 1999-12-24 IL IL14414699A patent/IL144146A0/xx unknown
- 1999-12-24 NZ NZ512767A patent/NZ512767A/en unknown
- 1999-12-24 AU AU24338/00A patent/AU2433800A/en not_active Abandoned
- 1999-12-24 HK HK02104075.8A patent/HK1042649A1/zh unknown
- 1999-12-24 WO PCT/EP1999/010369 patent/WO2000041695A1/de not_active Ceased
- 1999-12-24 EP EP99967980A patent/EP1140096A1/de not_active Withdrawn
- 1999-12-24 CN CN99816172A patent/CN1334732A/zh active Pending
- 1999-12-24 MX MXPA01006967A patent/MXPA01006967A/es not_active Application Discontinuation
- 1999-12-24 CZ CZ20012485A patent/CZ20012485A3/cs unknown
- 1999-12-24 BR BR9916887-1A patent/BR9916887A/pt not_active IP Right Cessation
- 1999-12-24 SK SK969-2001A patent/SK9692001A3/sk unknown
- 1999-12-24 KR KR1020017008692A patent/KR20010101442A/ko not_active Ceased
- 1999-12-24 CA CA002359253A patent/CA2359253A1/en not_active Abandoned
- 1999-12-24 TR TR2001/02008T patent/TR200102008T2/tr unknown
- 1999-12-24 HU HU0201149A patent/HUP0201149A3/hu unknown
- 1999-12-24 PL PL99348920A patent/PL348920A1/xx not_active Application Discontinuation
- 1999-12-24 US US09/889,162 patent/US6387912B1/en not_active Expired - Fee Related
- 1999-12-24 JP JP2000593306A patent/JP2002534465A/ja active Pending
-
2000
- 2000-01-11 MY MYPI20000084A patent/MY133107A/en unknown
-
2001
- 2001-07-03 ZA ZA200105475A patent/ZA200105475B/en unknown
- 2001-07-10 BG BG105689A patent/BG105689A/xx unknown
- 2001-07-10 NO NO20013409A patent/NO20013409L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000041695A1 (de) | 2000-07-20 |
| PL348920A1 (en) | 2002-06-17 |
| ID30022A (id) | 2001-11-01 |
| NO20013409L (no) | 2001-08-30 |
| IL144146A0 (en) | 2002-05-23 |
| MXPA01006967A (es) | 2002-04-10 |
| BG105689A (en) | 2002-02-28 |
| DE19900545A1 (de) | 2000-07-13 |
| NO20013409D0 (no) | 2001-07-10 |
| US6387912B1 (en) | 2002-05-14 |
| CA2359253A1 (en) | 2000-07-20 |
| EP1140096A1 (de) | 2001-10-10 |
| BR9916887A (pt) | 2001-11-20 |
| AU2433800A (en) | 2000-08-01 |
| HUP0201149A3 (en) | 2003-07-28 |
| CZ20012484A3 (cs) | 2002-05-15 |
| CZ20012485A3 (cs) | 2002-04-17 |
| MY133107A (en) | 2007-10-31 |
| HK1042649A1 (zh) | 2002-08-23 |
| NZ512767A (en) | 2003-05-30 |
| ZA200105475B (en) | 2002-10-03 |
| SK9692001A3 (en) | 2002-05-09 |
| HUP0201149A2 (hu) | 2002-07-29 |
| JP2002534465A (ja) | 2002-10-15 |
| KR20010101442A (ko) | 2001-11-14 |
| CN1334732A (zh) | 2002-02-06 |
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