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TR200102008T2 - Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı. - Google Patents

Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı.

Info

Publication number
TR200102008T2
TR200102008T2 TR2001/02008T TR200102008T TR200102008T2 TR 200102008 T2 TR200102008 T2 TR 200102008T2 TR 2001/02008 T TR2001/02008 T TR 2001/02008T TR 200102008 T TR200102008 T TR 200102008T TR 200102008 T2 TR200102008 T2 TR 200102008T2
Authority
TR
Turkey
Prior art keywords
treatment
cerebral ischemia
prophylaxis
pyridine derivatives
formula
Prior art date
Application number
TR2001/02008T
Other languages
English (en)
Inventor
Steiner Gerd
Schellhaas Kurt
Lubisch Wilfried
Holzenkamp Uta
Starck Dorothea
Knopp Monika
Szabo Laszlo
Emling Franz
Javier Garcia-Ladona Francisco
Hofmann Hans-Peter
Unger Liliane
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of TR200102008T2 publication Critical patent/TR200102008T2/tr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Bulus, ikame ajanlarinin açiklamada tanimlandigi gibi oldugu formül (I)'in pirimidin türevlerinin ve bunlarin fizyolojik olarak uygun tuzlarinin serebral iskeminin ve inmelerin önlenmesi ve tedavi edilmesi amaciyla ilaçlarin üretiminde kullanimi ile ilgilidir. (FORMÜL VAR)
TR2001/02008T 1999-01-11 1999-12-24 Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı. TR200102008T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19900545A DE19900545A1 (de) 1999-01-11 1999-01-11 Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie

Publications (1)

Publication Number Publication Date
TR200102008T2 true TR200102008T2 (tr) 2001-12-21

Family

ID=7893836

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/02008T TR200102008T2 (tr) 1999-01-11 1999-12-24 Serebral işemi profilaksı ve tedavisi için piridin türevlerinin kullanımı.

Country Status (24)

Country Link
US (1) US6387912B1 (tr)
EP (1) EP1140096A1 (tr)
JP (1) JP2002534465A (tr)
KR (1) KR20010101442A (tr)
CN (1) CN1334732A (tr)
AU (1) AU2433800A (tr)
BG (1) BG105689A (tr)
BR (1) BR9916887A (tr)
CA (1) CA2359253A1 (tr)
CZ (2) CZ20012484A3 (tr)
DE (1) DE19900545A1 (tr)
HK (1) HK1042649A1 (tr)
HU (1) HUP0201149A3 (tr)
ID (1) ID30022A (tr)
IL (1) IL144146A0 (tr)
MX (1) MXPA01006967A (tr)
MY (1) MY133107A (tr)
NO (1) NO20013409L (tr)
NZ (1) NZ512767A (tr)
PL (1) PL348920A1 (tr)
SK (1) SK9692001A3 (tr)
TR (1) TR200102008T2 (tr)
WO (1) WO2000041695A1 (tr)
ZA (1) ZA200105475B (tr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900673A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen
US6988199B2 (en) * 2000-07-07 2006-01-17 Message Secure Secure and reliable document delivery
JP4548882B2 (ja) * 1999-11-30 2010-09-22 興和創薬株式会社 4,5,6,7−テトラヒドロチエノ〔2,3−c〕ピリジン化合物
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10031390A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
CA2685753A1 (en) * 2007-05-09 2008-11-20 Neuromed Pharmaceuticals Ltd. Bicyclic pyrimidine derivatives as calcium channel blockers
US8927718B2 (en) 2009-08-26 2015-01-06 Takeda Pharmaceutical Company Limited Fused heterocyclic ring derivative and use thereof
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
US11753413B2 (en) 2020-06-19 2023-09-12 Incyte Corporation Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors
CA3188639A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
WO2022006456A1 (en) 2020-07-02 2022-01-06 Incyte Corporation Tricyclic pyridone compounds as jak2 v617f inhibitors
WO2022046989A1 (en) 2020-08-27 2022-03-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
US11919908B2 (en) 2020-12-21 2024-03-05 Incyte Corporation Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors
EP4298099A1 (en) 2021-02-25 2024-01-03 Incyte Corporation Spirocyclic lactams as jak2 v617f inhibitors
JP2025509672A (ja) 2022-03-17 2025-04-11 インサイト・コーポレイション Jak2 v617f阻害剤としての三環式尿素化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670560A (en) 1986-04-28 1987-06-02 Ortho Pharmaceutical Corporation Thienopyrimidine-2,4-dione derivatives and intermediates thereof
DE19636769A1 (de) 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724980A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724979A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
WO2000041695A1 (de) 2000-07-20
PL348920A1 (en) 2002-06-17
ID30022A (id) 2001-11-01
NO20013409L (no) 2001-08-30
IL144146A0 (en) 2002-05-23
MXPA01006967A (es) 2002-04-10
BG105689A (en) 2002-02-28
DE19900545A1 (de) 2000-07-13
NO20013409D0 (no) 2001-07-10
US6387912B1 (en) 2002-05-14
CA2359253A1 (en) 2000-07-20
EP1140096A1 (de) 2001-10-10
BR9916887A (pt) 2001-11-20
AU2433800A (en) 2000-08-01
HUP0201149A3 (en) 2003-07-28
CZ20012484A3 (cs) 2002-05-15
CZ20012485A3 (cs) 2002-04-17
MY133107A (en) 2007-10-31
HK1042649A1 (zh) 2002-08-23
NZ512767A (en) 2003-05-30
ZA200105475B (en) 2002-10-03
SK9692001A3 (en) 2002-05-09
HUP0201149A2 (hu) 2002-07-29
JP2002534465A (ja) 2002-10-15
KR20010101442A (ko) 2001-11-14
CN1334732A (zh) 2002-02-06

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