BG105689A - Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia - Google Patents
Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemiaInfo
- Publication number
- BG105689A BG105689A BG105689A BG10568901A BG105689A BG 105689 A BG105689 A BG 105689A BG 105689 A BG105689 A BG 105689A BG 10568901 A BG10568901 A BG 10568901A BG 105689 A BG105689 A BG 105689A
- Authority
- BG
- Bulgaria
- Prior art keywords
- utilization
- preventing
- pyrimidine derivatives
- treating cerebral
- cerebral ischaemia
- Prior art date
Links
- 206010008120 Cerebral ischaemia Diseases 0.000 title abstract 2
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title abstract 2
- 150000003230 pyrimidines Chemical class 0.000 title abstract 2
- 208000006011 Stroke Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19900545A DE19900545A1 (de) | 1999-01-11 | 1999-01-11 | Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie |
| PCT/EP1999/010369 WO2000041695A1 (de) | 1999-01-11 | 1999-12-24 | Verwendung von pyrimidinderivaten zur prophylaxe und therapie der zerebralen ischämie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG105689A true BG105689A (en) | 2002-02-28 |
Family
ID=7893836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG105689A BG105689A (en) | 1999-01-11 | 2001-07-10 | Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6387912B1 (xx) |
| EP (1) | EP1140096A1 (xx) |
| JP (1) | JP2002534465A (xx) |
| KR (1) | KR20010101442A (xx) |
| CN (1) | CN1334732A (xx) |
| AU (1) | AU2433800A (xx) |
| BG (1) | BG105689A (xx) |
| BR (1) | BR9916887A (xx) |
| CA (1) | CA2359253A1 (xx) |
| CZ (2) | CZ20012484A3 (xx) |
| DE (1) | DE19900545A1 (xx) |
| HK (1) | HK1042649A1 (xx) |
| HU (1) | HUP0201149A3 (xx) |
| ID (1) | ID30022A (xx) |
| IL (1) | IL144146A0 (xx) |
| MX (1) | MXPA01006967A (xx) |
| MY (1) | MY133107A (xx) |
| NO (1) | NO20013409L (xx) |
| NZ (1) | NZ512767A (xx) |
| PL (1) | PL348920A1 (xx) |
| SK (1) | SK9692001A3 (xx) |
| TR (1) | TR200102008T2 (xx) |
| WO (1) | WO2000041695A1 (xx) |
| ZA (1) | ZA200105475B (xx) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19900673A1 (de) | 1999-01-11 | 2000-07-13 | Basf Ag | Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen |
| US6988199B2 (en) * | 2000-07-07 | 2006-01-17 | Message Secure | Secure and reliable document delivery |
| JP4548882B2 (ja) * | 1999-11-30 | 2010-09-22 | 興和創薬株式会社 | ４，５，６，７−テトラヒドロチエノ〔２，３−ｃ〕ピリジン化合物 |
| DE10031389A1 (de) * | 2000-07-03 | 2002-01-17 | Knoll Ag | Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
| DE10031390A1 (de) * | 2000-07-03 | 2002-01-17 | Knoll Ag | Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
| DE10259382A1 (de) * | 2002-12-18 | 2004-07-01 | Abbott Gmbh & Co. Kg | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung |
| CA2685753A1 (en) * | 2007-05-09 | 2008-11-20 | Neuromed Pharmaceuticals Ltd. | Bicyclic pyrimidine derivatives as calcium channel blockers |
| US8927718B2 (en) | 2009-08-26 | 2015-01-06 | Takeda Pharmaceutical Company Limited | Fused heterocyclic ring derivative and use thereof |
| WO2021257857A1 (en) | 2020-06-19 | 2021-12-23 | Incyte Corporation | Naphthyridinone compounds as jak2 v617f inhibitors |
| US11753413B2 (en) | 2020-06-19 | 2023-09-12 | Incyte Corporation | Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors |
| CA3188639A1 (en) | 2020-07-02 | 2022-01-06 | Incyte Corporation | Tricyclic urea compounds as jak2 v617f inhibitors |
| WO2022006456A1 (en) | 2020-07-02 | 2022-01-06 | Incyte Corporation | Tricyclic pyridone compounds as jak2 v617f inhibitors |
| WO2022046989A1 (en) | 2020-08-27 | 2022-03-03 | Incyte Corporation | Tricyclic urea compounds as jak2 v617f inhibitors |
| US11919908B2 (en) | 2020-12-21 | 2024-03-05 | Incyte Corporation | Substituted pyrrolo[2,3-d]pyrimidine compounds as JAK2 V617F inhibitors |
| EP4298099A1 (en) | 2021-02-25 | 2024-01-03 | Incyte Corporation | Spirocyclic lactams as jak2 v617f inhibitors |
| JP2025509672A (ja) | 2022-03-17 | 2025-04-11 | インサイト・コーポレイション | Ｊａｋ２ ｖ６１７ｆ阻害剤としての三環式尿素化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4670560A (en) | 1986-04-28 | 1987-06-02 | Ortho Pharmaceutical Corporation | Thienopyrimidine-2,4-dione derivatives and intermediates thereof |
| DE19636769A1 (de) | 1996-09-10 | 1998-03-12 | Basf Ag | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724980A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| DE19724979A1 (de) | 1997-06-13 | 1998-12-17 | Basf Ag | 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
-
1999
- 1999-01-11 DE DE19900545A patent/DE19900545A1/de not_active Withdrawn
- 1999-12-22 ID IDW00200101717A patent/ID30022A/id unknown
- 1999-12-22 CZ CZ20012484A patent/CZ20012484A3/cs unknown
- 1999-12-24 IL IL14414699A patent/IL144146A0/xx unknown
- 1999-12-24 NZ NZ512767A patent/NZ512767A/en unknown
- 1999-12-24 AU AU24338/00A patent/AU2433800A/en not_active Abandoned
- 1999-12-24 HK HK02104075.8A patent/HK1042649A1/zh unknown
- 1999-12-24 WO PCT/EP1999/010369 patent/WO2000041695A1/de not_active Ceased
- 1999-12-24 EP EP99967980A patent/EP1140096A1/de not_active Withdrawn
- 1999-12-24 CN CN99816172A patent/CN1334732A/zh active Pending
- 1999-12-24 MX MXPA01006967A patent/MXPA01006967A/es not_active Application Discontinuation
- 1999-12-24 CZ CZ20012485A patent/CZ20012485A3/cs unknown
- 1999-12-24 BR BR9916887-1A patent/BR9916887A/pt not_active IP Right Cessation
- 1999-12-24 SK SK969-2001A patent/SK9692001A3/sk unknown
- 1999-12-24 KR KR1020017008692A patent/KR20010101442A/ko not_active Ceased
- 1999-12-24 CA CA002359253A patent/CA2359253A1/en not_active Abandoned
- 1999-12-24 TR TR2001/02008T patent/TR200102008T2/xx unknown
- 1999-12-24 HU HU0201149A patent/HUP0201149A3/hu unknown
- 1999-12-24 PL PL99348920A patent/PL348920A1/xx not_active Application Discontinuation
- 1999-12-24 US US09/889,162 patent/US6387912B1/en not_active Expired - Fee Related
- 1999-12-24 JP JP2000593306A patent/JP2002534465A/ja active Pending
-
2000
- 2000-01-11 MY MYPI20000084A patent/MY133107A/en unknown
-
2001
- 2001-07-03 ZA ZA200105475A patent/ZA200105475B/en unknown
- 2001-07-10 BG BG105689A patent/BG105689A/xx unknown
- 2001-07-10 NO NO20013409A patent/NO20013409L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000041695A1 (de) | 2000-07-20 |
| TR200102008T2 (tr) | 2001-12-21 |
| PL348920A1 (en) | 2002-06-17 |
| ID30022A (id) | 2001-11-01 |
| NO20013409L (no) | 2001-08-30 |
| IL144146A0 (en) | 2002-05-23 |
| MXPA01006967A (es) | 2002-04-10 |
| DE19900545A1 (de) | 2000-07-13 |
| NO20013409D0 (no) | 2001-07-10 |
| US6387912B1 (en) | 2002-05-14 |
| CA2359253A1 (en) | 2000-07-20 |
| EP1140096A1 (de) | 2001-10-10 |
| BR9916887A (pt) | 2001-11-20 |
| AU2433800A (en) | 2000-08-01 |
| HUP0201149A3 (en) | 2003-07-28 |
| CZ20012484A3 (cs) | 2002-05-15 |
| CZ20012485A3 (cs) | 2002-04-17 |
| MY133107A (en) | 2007-10-31 |
| HK1042649A1 (zh) | 2002-08-23 |
| NZ512767A (en) | 2003-05-30 |
| ZA200105475B (en) | 2002-10-03 |
| SK9692001A3 (en) | 2002-05-09 |
| HUP0201149A2 (hu) | 2002-07-29 |
| JP2002534465A (ja) | 2002-10-15 |
| KR20010101442A (ko) | 2001-11-14 |
| CN1334732A (zh) | 2002-02-06 |
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