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TR200002477T2 - Sikloheksandiol türevleri. - Google Patents

Sikloheksandiol türevleri.

Info

Publication number
TR200002477T2
TR200002477T2 TR2000/02477T TR200002477T TR200002477T2 TR 200002477 T2 TR200002477 T2 TR 200002477T2 TR 2000/02477 T TR2000/02477 T TR 2000/02477T TR 200002477 T TR200002477 T TR 200002477T TR 200002477 T2 TR200002477 T2 TR 200002477T2
Authority
TR
Turkey
Prior art keywords
cyclohexanediol derivatives
diseases
cyclohexanediol
derivatives
independently
Prior art date
Application number
TR2000/02477T
Other languages
English (en)
Turkish (tr)
Inventor
Barbier Pierre
Bauer Franz
Mohr Peter
Muller Marc
Pirson Wolfgang
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of TR200002477T2 publication Critical patent/TR200002477T2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/02Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
    • C07C47/19Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/263Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups acyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/26Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C47/273Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing hydroxy groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TR2000/02477T 1998-02-26 1999-02-20 Sikloheksandiol türevleri. TR200002477T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98103346 1998-02-26

Publications (1)

Publication Number Publication Date
TR200002477T2 true TR200002477T2 (tr) 2001-03-21

Family

ID=8231480

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02477T TR200002477T2 (tr) 1998-02-26 1999-02-20 Sikloheksandiol türevleri.

Country Status (21)

Country Link
US (1) US6184422B1 (es)
EP (1) EP1056716B1 (es)
JP (1) JP3507435B2 (es)
KR (1) KR20010041313A (es)
CN (1) CN1133621C (es)
AR (1) AR018120A1 (es)
AT (1) ATE229503T1 (es)
AU (1) AU751241B2 (es)
BR (1) BR9908315A (es)
CA (1) CA2320180C (es)
CO (1) CO4980898A1 (es)
DE (1) DE69904442T2 (es)
DK (1) DK1056716T3 (es)
ES (1) ES2188134T3 (es)
MA (1) MA26609A1 (es)
MY (1) MY133520A (es)
PE (1) PE20000267A1 (es)
PT (1) PT1056716E (es)
TR (1) TR200002477T2 (es)
WO (1) WO1999043646A1 (es)
ZA (1) ZA991550B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL145712A0 (en) * 1999-04-01 2002-07-25 Esperion Therapeutics Inc Ether compounds, compositions, and uses thereof
US6310262B1 (en) 1999-10-18 2001-10-30 Basilea Pharmaceutica Ag Process for preparing retiferol derivatives
EP1094060B1 (en) * 1999-10-18 2004-04-28 Basilea Pharmaceutica AG New process for the preparation of retiferol derivatives
AU2002214049A1 (en) * 2000-11-22 2002-06-03 F. Hoffmann-La Roche Ag Retiferol derivatives and their use in the treatment of skin diseases or conditions associated with photodamage
JPWO2003055854A1 (ja) * 2001-12-26 2005-05-12 中外製薬株式会社 2位に置換基を有するビタミンd誘導体
US6723755B2 (en) 2002-06-12 2004-04-20 Piotr Chomczynski Method of treating rosacea
US7812057B2 (en) * 2004-08-25 2010-10-12 Molecular Research Center, Inc. Cosmetic compositions
EP1931324B1 (en) * 2005-08-30 2015-01-28 Wisconsin Alumni Research Foundation Des-c,d analogs of 1alpha,25-dihydroxy-19-norvitamin d3
GB0712653D0 (en) 2007-06-28 2007-08-08 Syngenta Ltd Novel herbicides
WO2009094426A1 (en) * 2008-01-22 2009-07-30 Wisconsin Alumni Reasearch Foundation 13.13-dimethyl-des-c,d analogs of 1alpha, 25-dihydroxy-19-nor-vitamin d3 compounds and topical composition dosage forms and methods of treating skin conditions
EA201691980A1 (ru) * 2009-01-27 2017-07-31 БЕРГ ЭлЭлСи Способы уменьшения побочных эффектов, связанных с химиотерапией
KR101880032B1 (ko) 2009-08-14 2018-07-20 베르그 엘엘씨 탈모증 치료용 비타민 d3 및 이의 유사체들
EP3003497B1 (en) 2013-05-29 2024-02-14 BPGbio, Inc. Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN114044788A (zh) * 2021-08-12 2022-02-15 甘肃皓天医药科技有限责任公司 一种氟骨化醇cd环的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2209327T3 (es) 1993-07-09 2004-06-16 Laboratoire Theramex Nuevos analogos estructurales de la vitamina d.
PL174912B1 (pl) 1994-01-24 1998-10-30 Inst Farmaceutyczny Nowe związki farmakologicznie czynne z grupy witamin D i sposób ich otrzymywania
US5461116A (en) 1994-11-10 1995-10-24 Shell Oil Company Core functionalized star block copolymers
JP3276375B2 (ja) * 1997-05-23 2002-04-22 バジリア ファルマスーチカ アーゲー シクロヘキサンジオール誘導体

Also Published As

Publication number Publication date
WO1999043646A1 (en) 1999-09-02
ATE229503T1 (de) 2002-12-15
EP1056716B1 (en) 2002-12-11
CN1133621C (zh) 2004-01-07
MA26609A1 (fr) 2004-12-20
DE69904442D1 (en) 2003-01-23
ZA991550B (en) 1999-08-26
EP1056716A1 (en) 2000-12-06
PE20000267A1 (es) 2000-04-10
AR018120A1 (es) 2001-10-31
BR9908315A (pt) 2000-11-07
AU2624699A (en) 1999-09-15
CO4980898A1 (es) 2000-11-27
ES2188134T3 (es) 2003-06-16
MY133520A (en) 2007-11-30
CA2320180A1 (en) 1999-09-02
AU751241B2 (en) 2002-08-08
CA2320180C (en) 2005-06-07
US6184422B1 (en) 2001-02-06
JP2002504537A (ja) 2002-02-12
PT1056716E (pt) 2003-04-30
JP3507435B2 (ja) 2004-03-15
CN1291974A (zh) 2001-04-18
DK1056716T3 (da) 2003-04-07
KR20010041313A (ko) 2001-05-15
DE69904442T2 (de) 2003-09-25

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