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TR199800877T2 - Uyarici amino asit türevleri. - Google Patents

Uyarici amino asit türevleri.

Info

Publication number
TR199800877T2
TR199800877T2 TR1998/00877T TR9800877T TR199800877T2 TR 199800877 T2 TR199800877 T2 TR 199800877T2 TR 1998/00877 T TR1998/00877 T TR 1998/00877T TR 9800877 T TR9800877 T TR 9800877T TR 199800877 T2 TR199800877 T2 TR 199800877T2
Authority
TR
Turkey
Prior art keywords
amino acid
acid derivatives
stimulant
stimulant amino
nra
Prior art date
Application number
TR1998/00877T
Other languages
English (en)
Inventor
M. Massey Steven
A. Monn James
J. Valli Matthew
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9605434.1A external-priority patent/GB9605434D0/en
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of TR199800877T2 publication Critical patent/TR199800877T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

(I) formülü için bilesikler, ve bunlarin toksik-olmayan metabolik olarak kararsiz esterleri ya da amidleri ve bunlarin farmasötik açidan kabul edilebilir tuzlari metabotropik glutamat reseptör fonksiyonun modülatörleri olarak yararlidir, bu formülde, X, O, NRa, S, SO ya da SO2'yi temsil etmektedir ve R bu tarifnamede tanimlandigi gibidir.
TR1998/00877T 1995-11-16 1996-11-12 Uyarici amino asit türevleri. TR199800877T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US686495P 1995-11-16 1995-11-16
GBGB9605434.1A GB9605434D0 (en) 1996-03-15 1996-03-15 Excitatory amino acid derivatives

Publications (1)

Publication Number Publication Date
TR199800877T2 true TR199800877T2 (tr) 1998-09-21

Family

ID=26308935

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/00877T TR199800877T2 (tr) 1995-11-16 1996-11-12 Uyarici amino asit türevleri.

Country Status (22)

Country Link
EP (1) EP0774461B1 (tr)
KR (1) KR19990067598A (tr)
CN (1) CN1202167A (tr)
AR (2) AR004602A1 (tr)
AT (1) ATE319685T1 (tr)
AU (1) AU703409B2 (tr)
BR (1) BR9611511A (tr)
CA (1) CA2237910C (tr)
CO (1) CO4770955A1 (tr)
CZ (1) CZ150198A3 (tr)
DE (1) DE69635886T2 (tr)
EA (1) EA001617B1 (tr)
ES (1) ES2258771T3 (tr)
HU (1) HUP9903459A3 (tr)
IL (1) IL124487A (tr)
NO (1) NO982202D0 (tr)
NZ (1) NZ323205A (tr)
PE (1) PE17798A1 (tr)
PL (1) PL326695A1 (tr)
TR (1) TR199800877T2 (tr)
WO (1) WO1997018199A1 (tr)
YU (1) YU60796A (tr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2275777A1 (en) * 1997-01-29 1998-07-30 Louise Richman Levine Treatment for premenstrual dysphoric disorder
US6825211B1 (en) 1997-07-18 2004-11-30 Georgetown University Bicyclic metabotropic glutamate receptor ligands
CA2296310A1 (en) 1997-07-18 1999-01-28 Werner Tuckmantel Bicyclic metabotropic glutamate receptor ligands
DE19801648A1 (de) * 1998-01-17 1999-07-22 Bayer Ag alpha-Substituierte Lactone
DE19801647A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte beta,gamma-annellierte Lactone
DE19801636A1 (de) 1998-01-17 1999-07-22 Bayer Ag Substituierte bicyclische Lactone
DE19801646A1 (de) * 1998-01-17 1999-07-22 Bayer Ag Substituierte alpha,beta-annellierte Butyrolactone
GB2355982A (en) * 1999-11-03 2001-05-09 Lilly Co Eli Heterocyclic amino acids
TW200833674A (en) * 2002-06-11 2008-08-16 Lilly Co Eli Prodrugs of excitatory amino acids
CN102216243B (zh) * 2008-11-14 2014-09-03 Dsm精细化学奥地利Nfg两合公司 制备环丙烷衍生物的方法
WO2010111080A2 (en) 2009-03-27 2010-09-30 Eli Lilly And Company Optimized treatment of schizophrenia
US8735397B2 (en) 2010-03-29 2014-05-27 Vanderbilt University Method for treating schizophrenia and related diseases
SI2721012T1 (sl) 2011-06-17 2016-08-31 Eli Lilly And Company Derivati biciklo(3.1.0)heksan-2,6-dikarboksilne kisline kot agonisti mglu2 receptorja
AR089718A1 (es) 2012-02-01 2014-09-10 Lilly Co Eli AGONISTAS DE mGlu2/3
SMT201900545T1 (it) 2014-01-21 2019-11-13 Janssen Pharmaceutica Nv Combinazioni comprendenti modulatori allosterici positivi o agonisti ortosterici del recettore glutammatergico metabotropico sottotipo 2 e loro utilizzo
PH12019500127B1 (en) 2014-01-21 2022-05-04 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2572842A (en) * 1947-08-05 1951-10-30 Du Pont The n-carboanhydride of 2-amino-4, 6, 6-trimethylheptanoic acid and polymers therefrom
US4536330A (en) * 1982-09-23 1985-08-20 International Flavors & Fragrances Inc. 1-Hydroxymethyl-2-acyl cyclopropane derivatives and esters and cyclic condensation products thereof, organoleptic uses of same and processes for preparing same
WO1996004901A1 (en) * 1994-08-12 1996-02-22 Eli Lilly And Company Composition and method for treating anxiety
JP3618104B2 (ja) * 1994-08-12 2005-02-09 イーライ・リリー・アンド・カンパニー 薬物依存症に対する保護のための組成物及び方法
PL182285B1 (pl) * 1994-08-12 2001-12-31 Lilly Co Eli Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL

Also Published As

Publication number Publication date
ATE319685T1 (de) 2006-03-15
YU60796A (sh) 1998-12-23
IL124487A (en) 2001-01-11
PL326695A1 (en) 1998-10-26
CN1202167A (zh) 1998-12-16
HUP9903459A2 (hu) 2001-04-28
HUP9903459A3 (en) 2001-08-28
NO982202L (no) 1998-05-14
NZ323205A (en) 1999-06-29
BR9611511A (pt) 1999-05-04
DE69635886D1 (de) 2006-05-04
AU703409B2 (en) 1999-03-25
IL124487A0 (en) 1998-12-06
DE69635886T2 (de) 2006-10-19
EP0774461B1 (en) 2006-03-08
CA2237910C (en) 2005-12-27
AR004602A1 (es) 1998-12-16
EA001617B1 (ru) 2001-06-25
NO982202D0 (no) 1998-05-14
KR19990067598A (ko) 1999-08-25
PE17798A1 (es) 1998-04-18
CO4770955A1 (es) 1999-04-30
EP0774461A1 (en) 1997-05-21
AU7727996A (en) 1997-06-05
ES2258771T3 (es) 2006-09-01
WO1997018199A1 (en) 1997-05-22
CZ150198A3 (cs) 1998-10-14
EA199800377A1 (ru) 1998-10-29
CA2237910A1 (en) 1997-05-22
AR006748A1 (es) 1999-09-29

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