TNSN90053A1 - Procede d'obtention de nouveaux derives alcoyles en 17/21 de la 19- nor progesterone - Google Patents
Procede d'obtention de nouveaux derives alcoyles en 17/21 de la 19- nor progesteroneInfo
- Publication number
- TNSN90053A1 TNSN90053A1 TNTNSN90053A TNSN90053A TNSN90053A1 TN SN90053 A1 TNSN90053 A1 TN SN90053A1 TN TNSN90053 A TNTNSN90053 A TN TNSN90053A TN SN90053 A TNSN90053 A TN SN90053A TN SN90053 A1 TNSN90053 A1 TN SN90053A1
- Authority
- TN
- Tunisia
- Prior art keywords
- progesterone
- alkyl derivatives
- obtaining new
- carbon atoms
- branched chain
- Prior art date
Links
- 150000000318 19-norprogesterones Chemical class 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- VVUQRXPUVKXAIO-XFUVECHXSA-N 19-nor-5-androstenediol Chemical compound C1[C@@H](O)CC[C@@H]2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC=C21 VVUQRXPUVKXAIO-XFUVECHXSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
L'INVENTION SE RAPPORTE AU DOMAINE DE LA CHIMIE ET PLUS PARTICULIEREMENT A CELUI DE LA CHIMIE THERAPEUTIQUE. ELLE A PARTICULIEREMENT POUR OBJET LES 6-METHYL 19-NOR PREGNA 4,6-DIENES 17α, ET EVENTUELLEMENT, 21- ALCOYLES DE FORMULE GENERALE I (I) DANS LAQUELLE R" ET R' IDENTIQUES OU DIFFERENTS REPRESENTENT DE L'HYDROGENE OU UN RADICAL ALCOYLE AYANT DE 1 A 3 ATOMES DE CARBONE EN CHAINE DROITE OU RAMIFIEE ET R1 REPRESENTE UN RADICAL ALCOYLE INFERIEUR AYANT DE 1 A 6 ATOMES DE CARBONE, EN CHAINE DROITE OU RAMIFIEE ELLE A EGALEMENT POUR OBJET UN PROCEDE D'OBTENTION DES COMPOSES DE FORMULE GENERALE I ET LEUR EMPLOI COMME PRINCIPES ACTIFS DE MEDICAMENTS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8904910A FR2645864B1 (fr) | 1989-04-13 | 1989-04-13 | Nouveaux derives alcoyles en 17/21 de la 19-nor progesterone, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN90053A1 true TNSN90053A1 (fr) | 1991-03-05 |
Family
ID=9380699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN90053A TNSN90053A1 (fr) | 1989-04-13 | 1990-04-13 | Procede d'obtention de nouveaux derives alcoyles en 17/21 de la 19- nor progesterone |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0437552A1 (fr) |
| JP (1) | JPH04500523A (fr) |
| KR (1) | KR920700219A (fr) |
| AU (1) | AU635739B2 (fr) |
| FI (1) | FI906116A7 (fr) |
| FR (1) | FR2645864B1 (fr) |
| HU (1) | HU208152B (fr) |
| NO (1) | NO174393C (fr) |
| OA (1) | OA09632A (fr) |
| RU (1) | RU1836379C (fr) |
| TN (1) | TNSN90053A1 (fr) |
| WO (1) | WO1990012027A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2675047B1 (fr) * | 1991-04-09 | 1995-05-12 | Theramex | Nouvelles compositions pharmaceutiques anti-glaucomateuses et leur procede d'obtention. |
| WO1992022300A1 (fr) * | 1991-06-18 | 1992-12-23 | Laboratoire Theramex S.A. | Compositions oculaires contenant des steroïdes et leur utilisation pour le traitement du glaucome |
| FR2679236B1 (fr) * | 1991-07-18 | 1997-01-24 | Theramex | Nouveaux sterouides substitues en position 6, leurs procedes d'obtention et des compositions pharmaceutiques en renfermant. |
| HU231125B1 (hu) * | 2016-12-16 | 2020-12-28 | Richter Gedeon Nyrt. | Ipari eljárás Nomegesztrol-acetát előállítására |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3361744A (en) * | 1962-07-18 | 1968-01-02 | American Cyanamid Co | Novel 17-hydrocarbon substituted progesterones, intermediates and methods of preparing the same |
| FR2077877B1 (fr) * | 1970-02-20 | 1974-02-01 | Roussel Uclaf | |
| FR2552766B1 (fr) * | 1983-10-04 | 1987-06-26 | Theramex | Nouveau procede de preparation de derives de la serie du 17 a-hydroxy 19-nor progesterone |
| AU624096B2 (en) * | 1987-10-27 | 1992-06-04 | Laboratoire Theramex S.A. | Derivatives of 19-norprogesterone, their preparation and their use |
-
1989
- 1989-04-13 FR FR8904910A patent/FR2645864B1/fr not_active Expired - Fee Related
-
1990
- 1990-04-13 KR KR1019900702623A patent/KR920700219A/ko not_active Withdrawn
- 1990-04-13 HU HU904373A patent/HU208152B/hu not_active IP Right Cessation
- 1990-04-13 WO PCT/FR1990/000270 patent/WO1990012027A1/fr not_active Ceased
- 1990-04-13 TN TNTNSN90053A patent/TNSN90053A1/fr unknown
- 1990-04-13 FI FI906116A patent/FI906116A7/fi not_active Application Discontinuation
- 1990-04-13 AU AU55525/90A patent/AU635739B2/en not_active Ceased
- 1990-04-13 JP JP2506960A patent/JPH04500523A/ja active Pending
- 1990-04-13 EP EP90907142A patent/EP0437552A1/fr not_active Withdrawn
- 1990-12-11 NO NO905344A patent/NO174393C/no unknown
- 1990-12-12 RU SU904894526A patent/RU1836379C/ru active
- 1990-12-13 OA OA59916A patent/OA09632A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU904373D0 (en) | 1991-06-28 |
| FR2645864B1 (fr) | 1991-07-12 |
| AU635739B2 (en) | 1993-04-01 |
| HU208152B (en) | 1993-08-30 |
| AU5552590A (en) | 1990-11-05 |
| KR920700219A (ko) | 1992-02-19 |
| EP0437552A1 (fr) | 1991-07-24 |
| RU1836379C (ru) | 1993-08-23 |
| FI906116A0 (fi) | 1990-12-12 |
| JPH04500523A (ja) | 1992-01-30 |
| NO905344D0 (no) | 1990-12-11 |
| OA09632A (fr) | 1993-04-30 |
| FR2645864A1 (fr) | 1990-10-19 |
| NO174393B (no) | 1994-01-17 |
| NO905344L (no) | 1991-02-01 |
| WO1990012027A1 (fr) | 1990-10-18 |
| FI906116A7 (fi) | 1990-12-12 |
| HUT56579A (en) | 1991-09-30 |
| NO174393C (no) | 1994-04-27 |
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