SV2016005214A - Sistema de administración farmacológico - Google Patents
Sistema de administración farmacológicoInfo
- Publication number
- SV2016005214A SV2016005214A SV2016005214A SV2016005214A SV2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A SV 2016005214 A SV2016005214 A SV 2016005214A
- Authority
- SV
- El Salvador
- Prior art keywords
- thermoplastic polymer
- administration system
- therapeutic
- agent
- pharmacological administration
- Prior art date
Links
- 230000000144 pharmacologic effect Effects 0.000 title abstract 2
- 229920001169 thermoplastic Polymers 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
EN EL PRESENTE DOCUMENTO SE DESCRIBE UN SISTEMA DE ADMINISTRACIÓN FARMACOLÓGICO INTRAVAGINAL QUE COMPRENDE (I) UN NÚCLEO QUE COMPRENDE UN PRIMER POLÍMERO TERMOPLÁSTICO Y UN PRIMER AGENTE TERAPÉUTICO, EN EL QUE EL PRIMER AGENTE TERAPÉUTICO SE DISUELVE EN EL PRIMER POLÍMERO TERMOPLÁSTICO, Y (II) UNA CAPA EXTERNA QUE RODEA EL NÚCLEO QUE COMPRENDE UN SEGUNDO POLÍMERO TERMOPLÁSTICO, EN EL QUE EL PRIMER AGENTE TERAPÉUTICO ES MENOS PERMEABLE EN EL SEGUNDO POLÍMERO TERMOPLÁSTICO QUE EL PRIMER POLÍMERO TERMOPLÁSTICO, Y UN SEGUNDO AGENTE TERAPÉUTICO EN FORMA SÓLIDA, EN EL QUE EL SEGUNDO AGENTE TERAPÉUTICO ESTÁ CARGADO EN UNA PORCIÓN DE LA CAPA EXTERNA
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361914500P | 2013-12-11 | 2013-12-11 | |
| EP13196737 | 2013-12-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SV2016005214A true SV2016005214A (es) | 2016-11-21 |
Family
ID=49759119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SV2016005214A SV2016005214A (es) | 2013-12-11 | 2016-06-10 | Sistema de administración farmacológico |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10413504B2 (es) |
| EP (1) | EP3079660B1 (es) |
| JP (1) | JP6251396B2 (es) |
| KR (1) | KR101808977B1 (es) |
| CN (1) | CN105979930B (es) |
| AP (1) | AP2016009223A0 (es) |
| AU (1) | AU2014363724B2 (es) |
| BR (1) | BR112016013325B1 (es) |
| CA (1) | CA2931559C (es) |
| CR (1) | CR20160261A (es) |
| DO (1) | DOP2016000132A (es) |
| EA (1) | EA031802B1 (es) |
| HK (1) | HK1224208A1 (es) |
| IL (1) | IL245544A0 (es) |
| MA (1) | MA39059A1 (es) |
| MD (1) | MD20160079A2 (es) |
| MX (1) | MX2016007681A (es) |
| PE (1) | PE20160680A1 (es) |
| PH (1) | PH12016501083A1 (es) |
| SG (1) | SG11201604660VA (es) |
| SV (1) | SV2016005214A (es) |
| TW (1) | TW201607563A (es) |
| WO (1) | WO2015086491A1 (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
| US10596103B2 (en) | 2013-12-11 | 2020-03-24 | Merek Sharp & Dohme B.V. | Drug delivery system for delivery of anti-virals |
| WO2015094758A1 (en) | 2013-12-19 | 2015-06-25 | The Procter & Gamble Company | Shaping keratin fibres using an active agent comprising a functional group selected from the group consisting of: -c(=o)-, -c(=o)-h, and -c(=o)-o- |
| US11110046B2 (en) | 2013-12-19 | 2021-09-07 | The Procter And Gamble Company | Shaping keratin fibres using 2-hydroxypropane-1,2,3-tricarboxylic acid and/or 1,2,3,4-butanetetracarboxylic acid |
| WO2015094838A1 (en) | 2013-12-19 | 2015-06-25 | The Procter & Gamble Company | Shaping keratin fibres using a reducing composition and a fixing composition |
| CN105828793B (zh) | 2013-12-19 | 2019-06-18 | 宝洁公司 | 使用糖使角蛋白纤维成形 |
| MX353843B (es) | 2013-12-19 | 2018-01-30 | Procter & Gamble | Modelado de fibras de queratina con el uso de ácido oxoetanoico y/o derivados de este. |
| EP3082731B1 (en) | 2013-12-19 | 2018-07-04 | The Procter and Gamble Company | Shaping keratin fibres using an active agent comprising at least two functional groups selected from: -c(oh)- and -c(=o)oh |
| WO2015094837A1 (en) | 2013-12-19 | 2015-06-25 | The Procter & Gamble Company | Shaping keratin fibres using carbonate ester |
| EP3017809A1 (en) * | 2014-11-07 | 2016-05-11 | Ferring B.V. | Drug-device unit containing quinagolide |
| MX2017008203A (es) | 2014-12-19 | 2017-10-06 | Procter & Gamble | Metodo para dar forma a fibras de queratina. |
| WO2016100257A1 (en) | 2014-12-19 | 2016-06-23 | The Procter & Gamble Company | Shaping keratin fibres using arabinose and ethylene carbonate |
| MX2017016152A (es) | 2015-06-18 | 2018-04-18 | Procter & Gamble | Modelado de fibras de queratina mediante el uso de compuestos de dialdehido. |
| CN108135836A (zh) * | 2015-08-11 | 2018-06-08 | Ptt控股公司 | 递送装置 |
| EP3395335A1 (en) * | 2017-04-24 | 2018-10-31 | Kern Pharma, S.L. | Vaginal ring for the simultaneous release of two active ingredients |
| DE102017113166A1 (de) * | 2017-06-14 | 2018-12-20 | Amw Gmbh | Depotform zur Abgabe eines Östrogen-Wirkstoffs |
| BR112020023982A2 (pt) | 2018-05-24 | 2021-02-23 | Celanese Eva Performance Polymers Llc | dispositivo implantável para liberação prolongada de um composto de fármaco macromolecular |
| CA3087238A1 (en) | 2018-05-24 | 2019-11-28 | Celanese EVA Performance Polymers Corporation | Implantable device for sustained release of a macromolecular drug compound |
| WO2019222856A1 (en) | 2018-05-24 | 2019-11-28 | Nureva Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| US10918649B2 (en) | 2019-06-21 | 2021-02-16 | The Population Council, Inc. | System for providing birth control |
| BR112023022439A2 (pt) | 2021-04-26 | 2023-12-26 | Celanese Eva Performance Polymers Llc | Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular |
| EP4215180A1 (en) * | 2022-01-21 | 2023-07-26 | Sever Pharma Solutions | A drug delivery system |
| EP4465939A4 (en) * | 2022-01-21 | 2026-01-07 | The Population Council Inc | Intravaginal Combination Therapy Rings |
| EP4626399A1 (en) | 2022-12-02 | 2025-10-08 | VaRi Bioscience GmbH | Estriol vaginal ring |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3545439A (en) | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
| US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
| US3995633A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal Medicament dispensing device |
| US3995634A (en) | 1975-12-02 | 1976-12-07 | The Procter & Gamble Company | Vaginal cavity dispensing means and method |
| US4237885A (en) | 1978-10-23 | 1980-12-09 | Alza Corporation | Delivery system with mated members for storing and releasing a plurality of beneficial agents |
| US4292965A (en) | 1978-12-29 | 1981-10-06 | The Population Council, Inc. | Intravaginal ring |
| DE3040978A1 (de) | 1980-10-28 | 1982-05-27 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Vaginalring |
| US4629449A (en) | 1982-07-29 | 1986-12-16 | Alza Corporation | Vaginal dispenser for dispensing beneficial hormone |
| EP0162492B1 (en) | 1984-04-11 | 1989-08-02 | Thiemann Arzneimittel GmbH | Dosage units for controlled release of active material |
| EP0180264A1 (en) | 1984-10-12 | 1986-05-07 | Akzo N.V. | Release system for two or more active substances |
| US4816258A (en) | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
| ES2054784T3 (es) | 1987-08-08 | 1994-08-16 | Akzo Nv | Un metodo para la fabricacion de un implante. |
| AU3432689A (en) | 1988-03-24 | 1989-10-16 | Bukh Meditec A/S | Controlled release composition |
| US5766632A (en) | 1993-10-01 | 1998-06-16 | Legere Pharmaceuticals, Ltd. | Method of using lectins for contraception |
| JP3720386B2 (ja) | 1993-12-27 | 2005-11-24 | 住友製薬株式会社 | 薬物放出制御製剤 |
| EP0836473B1 (en) | 1995-07-04 | 2001-10-31 | Akzo Nobel N.V. | Ring-shaped devices |
| US5972372A (en) | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
| FR2754179B1 (fr) | 1996-10-08 | 1998-12-24 | Theramex | Nouvelle composition hormononale et son utilisation |
| TW358031B (en) | 1997-04-11 | 1999-05-11 | Akze Nobel N V | Drug delivery system for 2 or more active substances |
| CA2313196C (en) | 1997-12-12 | 2006-07-11 | Akzo Nobel Nv | A package for a vaginal ring |
| CA2315103A1 (en) | 1997-12-18 | 1999-06-24 | Eli Lilly And Company | Crystalline teriparatide |
| US6579533B1 (en) | 1999-11-30 | 2003-06-17 | Bioasborbable Concepts, Ltd. | Bioabsorbable drug delivery system for local treatment and prevention of infections |
| IL157771A0 (en) | 2001-03-27 | 2004-03-28 | Galen Chemicals Ltd | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
| EP1408876A4 (en) | 2001-06-22 | 2004-09-22 | Durect Corp | ZERO ORDER COAXIAL IMPLANTS WITH EXTENDED RELEASE |
| AU2002313517B2 (en) | 2001-08-31 | 2007-09-06 | Bayer Schering Pharma Oy | Drug delivery system |
| CN1596104A (zh) | 2001-09-28 | 2005-03-16 | 麦克内尔-Ppc股份有限公司 | 改进的释放剂型 |
| CN1242819C (zh) | 2002-06-07 | 2006-02-22 | 上海市计划生育科学研究所 | 一种新型阴道环及制备方法 |
| US6992219B2 (en) | 2002-08-09 | 2006-01-31 | Cephalon France | Modafinil polymorphic forms |
| TWI336627B (en) * | 2003-05-23 | 2011-02-01 | Organon Nv | Drug delivery system,and use and manufacturing method thereof |
| WO2005004837A1 (en) | 2003-07-10 | 2005-01-20 | Galen (Chemicals) Limited | Intravaginal drug delivery devices |
| WO2005030175A1 (en) * | 2003-09-29 | 2005-04-07 | Novo Nordisk Femcare Ag | Hrt formulations |
| JP2007530500A (ja) * | 2004-03-24 | 2007-11-01 | ナームローゼ・フエンノートチヤツプ・オルガノン | ポリエチレン酢酸ビニル共重合体に基づく薬物送達システム |
| KR20060046263A (ko) * | 2004-08-04 | 2006-05-17 | 도쿄파츠고교 가부시키가이샤 | 편평형 진동모터를 내장시킨 전자음향변환기 |
| TW200727920A (en) | 2005-06-21 | 2007-08-01 | Organon Nv | New regimens for oral monophasic contraceptives |
| EP2097063B1 (en) | 2006-11-20 | 2013-08-07 | Intervet International B.V. | Helically-shaped drug delivery system |
| US10258571B2 (en) | 2007-02-12 | 2019-04-16 | Particle Sciences, Inc. | Delivery devices containing encapsulated and/or practice-bound active pharmaceutical ingredients |
| PE20081895A1 (es) | 2007-03-26 | 2009-01-26 | Theramex | Regimen anticonceptivo oral |
| KR101696301B1 (ko) | 2007-09-07 | 2017-01-13 | 마티 테라퓨틱스 인코포레이티드 | 치료 약제의 서방성 약물 코어 |
| TW200930343A (en) | 2007-09-21 | 2009-07-16 | Organon Nv | Drug delivery system |
| TW200927141A (en) | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
| MX2012000948A (es) | 2009-07-21 | 2012-02-28 | Population Council Inc | Anillo vaginal gradiente multicapas. |
| EP2468750A1 (en) | 2010-12-13 | 2012-06-27 | Chemo Ibérica, S.A. | Polymorphic forms of asenapine maleate and processes for their preparation |
| TW201332585A (zh) | 2012-02-14 | 2013-08-16 | Chemo Res S L | 核鞘藥物遞送裝置 |
| US10413504B2 (en) | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
-
2014
- 2014-12-04 US US14/560,494 patent/US10413504B2/en active Active
- 2014-12-08 WO PCT/EP2014/076823 patent/WO2015086491A1/en not_active Ceased
- 2014-12-08 BR BR112016013325-0A patent/BR112016013325B1/pt active IP Right Grant
- 2014-12-08 KR KR1020167018119A patent/KR101808977B1/ko active Active
- 2014-12-08 JP JP2016538065A patent/JP6251396B2/ja active Active
- 2014-12-08 SG SG11201604660VA patent/SG11201604660VA/en unknown
- 2014-12-08 CR CR20160261A patent/CR20160261A/es unknown
- 2014-12-08 EP EP14809832.0A patent/EP3079660B1/en active Active
- 2014-12-08 PE PE2016000778A patent/PE20160680A1/es not_active Application Discontinuation
- 2014-12-08 CA CA2931559A patent/CA2931559C/en active Active
- 2014-12-08 AP AP2016009223A patent/AP2016009223A0/en unknown
- 2014-12-08 MA MA39059A patent/MA39059A1/fr unknown
- 2014-12-08 TW TW103142659A patent/TW201607563A/zh unknown
- 2014-12-08 MX MX2016007681A patent/MX2016007681A/es unknown
- 2014-12-08 AU AU2014363724A patent/AU2014363724B2/en active Active
- 2014-12-08 HK HK16112574.1A patent/HK1224208A1/zh unknown
- 2014-12-08 EA EA201691193A patent/EA031802B1/ru not_active IP Right Cessation
- 2014-12-08 CN CN201480067300.XA patent/CN105979930B/zh active Active
- 2014-12-08 MD MDA20160079A patent/MD20160079A2/ro not_active Application Discontinuation
-
2016
- 2016-05-08 IL IL245544A patent/IL245544A0/en unknown
- 2016-06-07 PH PH12016501083A patent/PH12016501083A1/en unknown
- 2016-06-10 DO DO2016000132A patent/DOP2016000132A/es unknown
- 2016-06-10 SV SV2016005214A patent/SV2016005214A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL245544A0 (en) | 2016-06-30 |
| DOP2016000132A (es) | 2016-07-31 |
| CA2931559A1 (en) | 2015-06-18 |
| US20150157561A1 (en) | 2015-06-11 |
| EA201691193A1 (ru) | 2016-09-30 |
| SG11201604660VA (en) | 2016-07-28 |
| KR20160095110A (ko) | 2016-08-10 |
| BR112016013325A2 (es) | 2017-08-08 |
| PH12016501083A1 (en) | 2016-07-25 |
| CN105979930B (zh) | 2019-11-19 |
| MD20160079A2 (ro) | 2016-10-31 |
| TW201607563A (zh) | 2016-03-01 |
| KR101808977B1 (ko) | 2017-12-13 |
| AU2014363724B2 (en) | 2017-02-23 |
| EP3079660B1 (en) | 2021-03-03 |
| JP6251396B2 (ja) | 2017-12-20 |
| JP2016539991A (ja) | 2016-12-22 |
| AU2014363724A1 (en) | 2016-05-26 |
| CR20160261A (es) | 2016-08-16 |
| AP2016009223A0 (en) | 2016-05-31 |
| PE20160680A1 (es) | 2016-07-31 |
| CN105979930A (zh) | 2016-09-28 |
| MX2016007681A (es) | 2016-10-14 |
| HK1224208A1 (zh) | 2017-08-18 |
| BR112016013325B1 (pt) | 2022-11-29 |
| WO2015086491A1 (en) | 2015-06-18 |
| EP3079660A1 (en) | 2016-10-19 |
| MA39059A1 (fr) | 2018-08-31 |
| CA2931559C (en) | 2018-03-13 |
| EA031802B1 (ru) | 2019-02-28 |
| US10413504B2 (en) | 2019-09-17 |
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