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SV2009003173A - Analogos de 2-fenoxipirimidinonas ref. 66513-sv (72021) - Google Patents

Analogos de 2-fenoxipirimidinonas ref. 66513-sv (72021)

Info

Publication number
SV2009003173A
SV2009003173A SV2009003173A SV2009003173A SV2009003173A SV 2009003173 A SV2009003173 A SV 2009003173A SV 2009003173 A SV2009003173 A SV 2009003173A SV 2009003173 A SV2009003173 A SV 2009003173A SV 2009003173 A SV2009003173 A SV 2009003173A
Authority
SV
El Salvador
Prior art keywords
phenoxypirimidinone
analogs
receiver
ref
compounds
Prior art date
Application number
SV2009003173A
Other languages
English (en)
Inventor
Rajagopal Bakthavatchalam
Scott Michael Capitosti
Jianjun Xu
Bertrand L Chenard
Manuka Ghosh
Charles A Blum
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Publication of SV2009003173A publication Critical patent/SV2009003173A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
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  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
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  • Virology (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • AIDS & HIV (AREA)
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Abstract

SE PROVEEN ANÁLOGOS DE 2-FENOXIPIRIMIDINONA, DE LA FORMULA: (VER FORMULA); EN DONDE LAS VARIABLES SON COMO SE DESCRIBE AQUÍ; DICHOS COMPUESTOS SON LIGANDOS QUE SE PUEDEN USAR PARA MODULAR ACTIVIDAD DE RECEPTOR ESPECIFICA IN VIVO O IN VITRO, Y SON PARTICULARMENTE ÚTILES EN EL TRATAMIENTO DE CONDICIONES ASOCIADAS CON ACTIVACIÓN DE RECEPTOR PATOLÓGICA EN HUMANOS, ANIMALES DE COMPAÑÍA DOMESTICADOS Y ANIMALES DE GANADO; SE PROVEEN COMPOSICIONES FARMACÉUTICAS Y MÉTODOS PARA USAR DICHOS COMPUESTOS PARA TRATAR ESOS TRASTORNOS, COMO LO SON LOS MÉTODOS PARA USAR DICHOS LIGANDOS PARA ESTUDIOS DE LOCALIZACIÓN DE RECEPTOR
SV2009003173A 2006-08-23 2009-02-20 Analogos de 2-fenoxipirimidinonas ref. 66513-sv (72021) SV2009003173A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82325806P 2006-08-23 2006-08-23

Publications (1)

Publication Number Publication Date
SV2009003173A true SV2009003173A (es) 2010-08-10

Family

ID=39107411

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2009003173A SV2009003173A (es) 2006-08-23 2009-02-20 Analogos de 2-fenoxipirimidinonas ref. 66513-sv (72021)

Country Status (22)

Country Link
US (2) US8003656B2 (es)
EP (1) EP2061794B1 (es)
JP (1) JP5421108B2 (es)
KR (1) KR20090043583A (es)
CN (2) CN101506210A (es)
AU (1) AU2007288203B2 (es)
BR (1) BRPI0716582A2 (es)
CA (1) CA2660957C (es)
CO (1) CO6150167A2 (es)
CR (1) CR10675A (es)
EA (1) EA200900330A1 (es)
ES (1) ES2399928T3 (es)
GT (1) GT200900040A (es)
IL (1) IL197043A0 (es)
MA (1) MA30720B1 (es)
MX (1) MX2009002066A (es)
NI (1) NI200900023A (es)
NO (1) NO20091182L (es)
SV (1) SV2009003173A (es)
TW (1) TW200825089A (es)
WO (1) WO2008024438A2 (es)
ZA (1) ZA200901163B (es)

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GT200900040A (es) 2010-03-16
US20120208829A1 (en) 2012-08-16
CA2660957C (en) 2016-10-11
WO2008024438A3 (en) 2008-11-27
TW200825089A (en) 2008-06-16
EP2061794A4 (en) 2010-09-08
EP2061794B1 (en) 2012-12-05
CN104292229A (zh) 2015-01-21
IL197043A0 (en) 2009-11-18
ES2399928T3 (es) 2013-04-04
BRPI0716582A2 (pt) 2013-10-08
JP2010502576A (ja) 2010-01-28
CN101506210A (zh) 2009-08-12
US8003656B2 (en) 2011-08-23
US20090069347A1 (en) 2009-03-12
MX2009002066A (es) 2009-03-06
JP5421108B2 (ja) 2014-02-19
EA200900330A1 (ru) 2009-08-28
US8759361B2 (en) 2014-06-24
CR10675A (es) 2009-04-17
KR20090043583A (ko) 2009-05-06
CA2660957A1 (en) 2008-02-28
ZA200901163B (en) 2010-08-25
AU2007288203B2 (en) 2013-01-17
MA30720B1 (fr) 2009-09-01
EP2061794A2 (en) 2009-05-27
CO6150167A2 (es) 2010-04-20
WO2008024438A2 (en) 2008-02-28
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AU2007288203A1 (en) 2008-02-28
NO20091182L (no) 2009-05-14

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