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SV2003000588A - Nuevos compuestos de 1,4-dihidropiridina como antagonistas de bradicinina ref. pc9981adrg/bb - Google Patents

Nuevos compuestos de 1,4-dihidropiridina como antagonistas de bradicinina ref. pc9981adrg/bb

Info

Publication number
SV2003000588A
SV2003000588A SV2001000588A SV2001000588A SV2003000588A SV 2003000588 A SV2003000588 A SV 2003000588A SV 2001000588 A SV2001000588 A SV 2001000588A SV 2001000588 A SV2001000588 A SV 2001000588A SV 2003000588 A SV2003000588 A SV 2003000588A
Authority
SV
El Salvador
Prior art keywords
compounds
pc9981adrg
bradicinine
dihydropiridine
ref
Prior art date
Application number
SV2001000588A
Other languages
English (en)
Inventor
Takafumi Ikeda
Yasuhiro Katsu
Makoto Kawai
Mitsuhiro Kawamura
Yuji Shishido
Noriaki Murase
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of SV2003000588A publication Critical patent/SV2003000588A/es

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE FORMULA, VER FORMULA, EN LA QUE CADA A ES INDEPENDIENTEMENTE HALO; Y ES -(CH2)M-, -C(O)- O -S(O)-; R1 Y R2 SON INDEPENDIENTEMENTE ALQUILO C1-4; R3 ES AZACICLOALQUILO SUSTITUIDO, ETC. ; R4 ES FENILO SUSTITUIDO EN LA POSICION 2 CON UN SUSTITUYENTE SELECCIONADO ENTRE ALQUILO C1-7 SUSTITUIDO, ALCOXI C1-7 SUSTITUIDO, AMINA, ETC. ; R5 ES HIDROGENO O ALQUILO C1-4, M ES 0, 1,Ó 2; Y N ES 0, 1, 2, 3, 4 Ó 5. LA PRESENTE INVENCION TAMBIEN SE REFIERE A COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS Y AL USO DE TALES COMPUESTOS EN EL TRATAMIENTO Y PREVENCION DE LA INFLAMACION, ASMA, RINITIS ALERGICA, DOLOR Y OTROS TRASTORNOS
SV2001000588A 2000-08-10 2001-08-09 Nuevos compuestos de 1,4-dihidropiridina como antagonistas de bradicinina ref. pc9981adrg/bb SV2003000588A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22455800P 2000-08-10 2000-08-10

Publications (1)

Publication Number Publication Date
SV2003000588A true SV2003000588A (es) 2003-01-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
SV2001000588A SV2003000588A (es) 2000-08-10 2001-08-09 Nuevos compuestos de 1,4-dihidropiridina como antagonistas de bradicinina ref. pc9981adrg/bb

Country Status (21)

Country Link
US (1) US6653313B2 (es)
EP (1) EP1307449B1 (es)
JP (1) JP2004505973A (es)
AP (1) AP2001002238A0 (es)
AR (1) AR034555A1 (es)
AT (1) ATE312099T1 (es)
AU (1) AU2001270947A1 (es)
BR (1) BR0113071A (es)
CA (1) CA2418908C (es)
CR (1) CR6859A (es)
DE (1) DE60115661T2 (es)
ES (1) ES2257422T3 (es)
GT (1) GT200100153A (es)
IL (1) IL153224A0 (es)
IS (1) IS6639A (es)
MX (1) MXPA03001204A (es)
PA (1) PA8525001A1 (es)
PE (1) PE20020467A1 (es)
SV (1) SV2003000588A (es)
TN (1) TNSN01124A1 (es)
WO (1) WO2002012235A1 (es)

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TNSN97037A1 (fr) * 1996-02-19 2005-03-15 Pfizer Derives de 1,4 -dihydropyridine, procede pour leur preparation et compositions pharmaceutiques les contenant.
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EP1307449A1 (en) 2003-05-07
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CR6859A (es) 2003-11-25
AU2001270947A1 (en) 2002-02-18
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US20020161006A1 (en) 2002-10-31
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CA2418908A1 (en) 2002-02-14
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