IS6639A - 1,4-díhýdrópýridín sem bradykínin mótlyf - Google Patents

1,4-díhýdrópýridín sem bradykínin mótlyf

Info

Publication number: IS6639A
Authority: IS; Iceland
Prior art keywords: dihydropyridine; bradykinin antagonist; bradykinin; antagonist
Prior art date: 2000-08-10

Application number

IS6639A

Other languages

English (en)

Inventor

Ikeda Takafumi

Kato Tomoki

Katsu Yasuhiro

Kawai Makoto

Kawamura Mitsuhiro

Shishido Yuji

Murase Noriaki

Original Assignee

Pfizer Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-10

Filing date

2002-11-28

Publication date

2002-11-28

2002-11-28 Application filed by Pfizer Inc. filed Critical Pfizer Inc.

2002-11-28 Publication of IS6639A publication Critical patent/IS6639A/is

Links

YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical compound C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title 1
UYRCOTSOPWOSJK-JXTBTVDRSA-N bradykinin antagonist Chemical compound C1C2=CC=CC=C2CC1[C@@H](NC(=O)C(CO)NC(=O)C(NC(=O)CNC(=O)[C@H]1N(C[C@H](O)C1)C(=O)C1N(CCC1)C(=O)C(CCCNC(N)=N)NC(=O)[C@@H](CCCNC(N)=N)NC(=N)CCCCCCC(=N)N[C@H](CCCNC(N)=N)C(=O)NC(CCCNC(N)=N)C(=O)N1C(CCC1)C(=O)N1[C@@H](C[C@@H](O)C1)C(=O)NCC(=O)NC(C1CC2=CC=CC=C2C1)C(=O)NC(CO)C(=O)N[C@H](C1CC2=CC=CC=C2C1)C(=O)N1C2CCCCC2CC1C(=O)NC(CCCNC(N)=N)C(O)=O)C1CC2=CC=CC=C2C1)C(=O)N1C2CCCCC2CC1C(=O)NC(CCCNC(=N)N)C(O)=O UYRCOTSOPWOSJK-JXTBTVDRSA-N 0.000 title 1
239000003152 bradykinin antagonist Substances 0.000 title 1

Classifications

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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Obesity (AREA)
Psychology (AREA)
Ophthalmology & Optometry (AREA)
Communicable Diseases (AREA)
Immunology (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)

IS6639A 2000-08-10 2002-11-28 1,4-díhýdrópýridín sem bradykínin mótlyf IS6639A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US22455800P	2000-08-10	2000-08-10
PCT/IB2001/001346 WO2002012235A1 (en)	2000-08-10	2001-07-26	1,4-dihydropyridines as bradykinin antagonists

Publications (1)

Publication Number	Publication Date
IS6639A true IS6639A (is)	2002-11-28

Family

ID=22841188

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS6639A IS6639A (is)	2000-08-10	2002-11-28	1,4-díhýdrópýridín sem bradykínin mótlyf

Country Status (21)

Country	Link
US (1)	US6653313B2 (is)
EP (1)	EP1307449B1 (is)
JP (1)	JP2004505973A (is)
AP (1)	AP2001002238A0 (is)
AR (1)	AR034555A1 (is)
AT (1)	ATE312099T1 (is)
AU (1)	AU2001270947A1 (is)
BR (1)	BR0113071A (is)
CA (1)	CA2418908C (is)
CR (1)	CR6859A (is)
DE (1)	DE60115661T2 (is)
ES (1)	ES2257422T3 (is)
GT (1)	GT200100153A (is)
IL (1)	IL153224A0 (is)
IS (1)	IS6639A (is)
MX (1)	MXPA03001204A (is)
PA (1)	PA8525001A1 (is)
PE (1)	PE20020467A1 (is)
SV (1)	SV2003000588A (is)
TN (1)	TNSN01124A1 (is)
WO (1)	WO2002012235A1 (is)

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JP4746318B2 (ja) *	2002-08-30	2011-08-10	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	シクレソニドと抗ヒスタミン剤との組合せ物を含有するアレルギー性鼻炎の治療用医薬組成物
MXPA05007843A (es) *	2003-01-24	2005-10-18	Elan Pharm Inc	Composicion y tratamiento de enfermedades desmielinizantes y paralisis por administracion de agentes de remielinizantes.
WO2006071775A2 (en) *	2004-12-29	2006-07-06	Elan Pharmaceuticals, Inc.	Novel compounds useful for bradykinin b1 receptor antagonism
ATE540042T1 (de) *	2008-06-09	2012-01-15	Bayer Pharma AG	Annelierte 4-(indazolyl)-1,4- dihydropyridinderivate als c-met-mediatoren
WO2010127381A1 (en) *	2009-05-08	2010-11-11	James Cook University	Diagnosis, monitoring, prognosis, prevention and treatment of aneurysms
JP5637710B2 (ja) *	2010-03-24	2014-12-10	株式会社トクヤマ	｛２−アミノ−１，４−ジヒドロ−６−メチル−４−（３−ニトロフェニル）−３，５−ピリジンジカルボン酸３−（１−ジフェニルメチルアゼチジン−３−イル）エステル５−イソプロピルエステル｝の製造方法
AP2014007805A0 (en)	2011-12-28	2014-07-31	Cytokinetics Inc The Regents Of The University Of California	Substituted benzaldehyde compounds and methods fortheir use in increasing tissue oxygenation
WO2013102145A1 (en)	2011-12-28	2013-07-04	Global Blood Therapeutics, Inc.	Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
US9422279B2 (en)	2013-03-15	2016-08-23	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en)	2013-03-15	2017-10-31	Global Blood Therapeutics, Inc.	Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en)	2013-03-15	2019-04-23	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en)	2013-03-15	2014-09-18	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
MY180206A (en)	2013-03-15	2020-11-25	Global Blood Therapeutics Inc	Compounds and uses thereof for the modulation of hemoglobin
ES2852054T3 (es)	2013-03-15	2021-09-10	Global Blood Therapeutics Inc	Compuestos y usos de los mismos para la modulación de hemoglobina
US9458139B2 (en)	2013-03-15	2016-10-04	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en)	2013-03-15	2017-03-28	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en)	2013-03-15	2018-10-16	Global Blood Therapeutics, Inc.	Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US8952171B2 (en)	2013-03-15	2015-02-10	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
AP2015008718A0 (en)	2013-03-15	2015-09-30	Global Blood Therapeutics Inc	Compounds and uses thereof for the modulation of hemoglobin
SMT202200292T1 (it)	2013-10-25	2022-09-14	Blueprint Medicines Corp	Inibitori del recettore del fattore di crescita dei fibroblasti
EA202092627A1 (ru)	2013-11-18	2021-09-30	Глобал Блад Терапьютикс, Инк.	Соединения и их применения для модуляции гемоглобина
SG10201911668VA (en)	2014-02-07	2020-01-30	Global Blood Therapeutics Inc	Crystalline polymorphs of the free base of 2-hydroxy-6-((2-(1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
MA41841A (fr)	2015-03-30	2018-02-06	Global Blood Therapeutics Inc	Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
HUE072191T2 (hu)	2015-12-04	2025-10-28	Global Blood Therapeutics Inc	A 2-hidoxi-6-((2-(1-izopropil-1H-pirazol-5-il)piridin-3-il)metoxi)benzaldehid adagolási rendje
TWI663160B (zh)	2016-05-12	2019-06-21	全球血液治療公司	用於合成2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)-吡啶-3-基)甲氧基)苯甲醛之方法
TW202332423A (zh)	2016-10-12	2023-08-16	美商全球血液治療公司	包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
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JPH11106375A (ja) *	1997-08-18	1999-04-20	Pfizer Pharmaceut Inc	ブラジキニンアンタゴニストとしての光学的に活性な１，４−ジヒドロピリジン化合物
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ATE257479T1 (de)	1999-12-10	2004-01-15	Pfizer	5-ring heteroarylsubstituierte 1,4- dihydropyridine als bradykinin antagonisten

2001
- 2001-07-11 US US09/903,157 patent/US6653313B2/en not_active Expired - Fee Related
- 2001-07-26 ES ES01949836T patent/ES2257422T3/es not_active Expired - Lifetime
- 2001-07-26 IL IL15322401A patent/IL153224A0/xx unknown
- 2001-07-26 AU AU2001270947A patent/AU2001270947A1/en not_active Abandoned
- 2001-07-26 DE DE60115661T patent/DE60115661T2/de not_active Expired - Fee Related
- 2001-07-26 BR BR0113071-4A patent/BR0113071A/pt not_active IP Right Cessation
- 2001-07-26 WO PCT/IB2001/001346 patent/WO2002012235A1/en not_active Ceased
- 2001-07-26 CA CA002418908A patent/CA2418908C/en not_active Expired - Fee Related
- 2001-07-26 AT AT01949836T patent/ATE312099T1/de not_active IP Right Cessation
- 2001-07-26 MX MXPA03001204A patent/MXPA03001204A/es unknown
- 2001-07-26 EP EP01949836A patent/EP1307449B1/en not_active Expired - Lifetime
- 2001-07-26 JP JP2002518210A patent/JP2004505973A/ja active Pending
- 2001-07-26 AP APAP/P/2001/002238A patent/AP2001002238A0/en unknown
- 2001-07-27 GT GT200100153A patent/GT200100153A/es unknown
- 2001-08-08 PE PE2001000796A patent/PE20020467A1/es not_active Application Discontinuation
- 2001-08-09 AR ARP010103819A patent/AR034555A1/es not_active Application Discontinuation
- 2001-08-09 SV SV2001000588A patent/SV2003000588A/es not_active Application Discontinuation
- 2001-08-09 TN TNTNSN01124A patent/TNSN01124A1/fr unknown
- 2001-08-10 PA PA20018525001A patent/PA8525001A1/es unknown
2002
- 2002-11-28 IS IS6639A patent/IS6639A/is unknown
- 2002-12-13 CR CR6859A patent/CR6859A/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE60115661T2 (de)	2006-08-24
IL153224A0 (en)	2003-07-06
MXPA03001204A (es)	2003-06-30
ATE312099T1 (de)	2005-12-15
EP1307449A1 (en)	2003-05-07
ES2257422T3 (es)	2006-08-01
PA8525001A1 (es)	2002-08-26
CR6859A (es)	2003-11-25
AU2001270947A1 (en)	2002-02-18
DE60115661D1 (de)	2006-01-12
BR0113071A (pt)	2003-07-01
US6653313B2 (en)	2003-11-25
AR034555A1 (es)	2004-03-03
CA2418908C (en)	2006-05-09
PE20020467A1 (es)	2002-06-14
US20020161006A1 (en)	2002-10-31
TNSN01124A1 (fr)	2005-11-10
SV2003000588A (es)	2003-01-13
CA2418908A1 (en)	2002-02-14
EP1307449B1 (en)	2005-12-07
JP2004505973A (ja)	2004-02-26
WO2002012235A1 (en)	2002-02-14
AP2001002238A0 (en)	2001-09-30
GT200100153A (es)	2002-07-03

Publication	Publication Date	Title
IS6639A (is)	2002-11-28	1,4-díhýdrópýridín sem bradykínin mótlyf
IS6561A (is)	2002-09-20	Bensóamíð píperidín efnasambönd sem P-efnis mótlyf
DE60135166D1 (de)	2008-09-11	Werkzeugmaschinen
DE60107628D1 (de)	2005-01-13	Werkzeugmaschine
IS6886A (is)	2003-07-24	Kínasólín sem MMP-13 hindrar
IS5941A (is)	2001-05-15	Píperidín sem CCR5 stillar
FI6788U1 (fi)	2005-09-14	Amlodipiinimaleaatti
DE60136556D1 (de)	2008-12-24	Werkzeugmaschine
DE60019735D1 (de)	2005-06-02	Werkzeugmaschine
DE50107891D1 (de)	2005-12-08	Werkzeugmaschine
DE60112098D1 (de)	2005-08-25	Werkzeugmaschine
MXPA03004652A (es)	2003-09-05	Derivados de piperidina como antagonistas selectivos de subtipo de n-metil-d-aspartato.
DE60109984D1 (de)	2005-05-19	Werkzeugmaschine
DE50100576D1 (de)	2003-10-09	Werkzeugmaschine
DE60101299D1 (de)	2004-01-08	Werkzeugmaschine
IS7303A (is)	2004-06-08	3-fenýl-2-arýlalkýlþíóprópíónsýruafleiður sem valvís gerandefni PPAR-ALFA
DE60110016D1 (de)	2005-05-19	Werkzeugmaschine
ITBO20000529A0 (it)	2000-09-13	Macchina utensile
GB0110837D0 (en)	2001-06-27	A router
FI20000978L (fi)	2001-10-27	Työkoneen puomisto
ITBO20000516A0 (it)	2000-09-06	Macchina utensile
NO20010609D0 (no)	2001-02-05	Dreieanordning
ITMO20000181A0 (it)	2000-08-31	Utensile estrattore
DE60100078D1 (de)	2003-02-20	Verbesserte Werkzeugmaschine
IT1320878B1 (it)	2003-12-10	Armadietto portautensili .