[go: up one dir, main page]

SU561508A3 - Способ получени производных 2-бензоил3-(аминоацетиламидо)-пиридина или их солей - Google Patents

Способ получени производных 2-бензоил3-(аминоацетиламидо)-пиридина или их солей

Info

Publication number
SU561508A3
SU561508A3 SU2043813A SU2043813A SU561508A3 SU 561508 A3 SU561508 A3 SU 561508A3 SU 2043813 A SU2043813 A SU 2043813A SU 2043813 A SU2043813 A SU 2043813A SU 561508 A3 SU561508 A3 SU 561508A3
Authority
SU
USSR - Soviet Union
Prior art keywords
benzoyl
amino
acetylamido
salts
preparing
Prior art date
Application number
SU2043813A
Other languages
English (en)
Inventor
Фон Бебенбург Вальтер
Офферманнс Хериберт
Original Assignee
Дегусса (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дегусса (Фирма) filed Critical Дегусса (Фирма)
Application granted granted Critical
Publication of SU561508A3 publication Critical patent/SU561508A3/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Description

натром, или действием разбавлеш1Ь Х кислот, например разбавленной уксусной кислоты.
П р и м е р 1. 2 Бензоил 3 - (аминоацетиламадо ) 6 - хлорпиридин.
100 г 2 - бензоил - 3 - бромацетиламидо - 6 «лорпиридина прибавл ют к 400 мл жидкого аммиака при перемеилшании. Смесь перемешивают 4 час при -40° С, затем упаривают аммиак. Твердый остаток раствор ют в 400 мл хлористого метилена и раствор промьтают один раз 400 мл воды. ОрганиЧЕСкий слой сушат и при перемешивании смешивают с 400 мл бензина, при этом осаждаетс  требуемый продукт. Выход 50 г, т.пл. 200-201°С.
Исходное вещество получают следующим образом: в раствор 312 г 2-бензоил-3 - амшю - 6 хлоргеиридина в 1250мл ацетона прибавл ют по капл м Б течение 15 мин 135 мл бромацетилхлорида при охлаждении льдом. Через некоторое врем  вьтристаллизовьшаетс  продукт реакции, который через 2 час отфильтровывают. Выход 363 г, Т.Ш1. 128°С,
Пример 2. 2- Бензоил - 3 (этиламиноацетиламвдо ) 6 - хлорпиридин.
В смесь 50 г этиламина и 150 мл метанола прибавл ют при комнатной температуре 34,4 г 2 бензоил 3 - бромацетиламндо - 6 хлорпиридищ при перемешивании. TeNmeparypa повьшгаетс  до 30°С. Перемешивают 1 час, отфильтровывают .рсадс (к,д)аствор ют в диоксане, смешивают с 6 и. зтанольным раствором хлористого водорода, гид.рохлорид отфильтровьгоают и промьшают диоксаном . Выход 23,8 г, т.пл. 196-200°С.

Claims (1)

1. Вейганд-Х льгетаг. Методы эксперимента в органической химии. М., Хнню , 1968, с. 413.
SU2043813A 1972-05-10 1974-07-17 Способ получени производных 2-бензоил3-(аминоацетиламидо)-пиридина или их солей SU561508A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT411372A AT321303B (de) 1972-05-10 1972-05-10 Verfahren zur Herstellung von neuen 2-Benzoyl-3-amino-pyridin-Verbindungen und deren Salzen

Publications (1)

Publication Number Publication Date
SU561508A3 true SU561508A3 (ru) 1977-06-05

Family

ID=3559825

Family Applications (4)

Application Number Title Priority Date Filing Date
SU1914703A SU538662A3 (ru) 1972-05-10 1973-04-26 Способ получени производных 2-бензоил-3-аминопиридина или их солей
SU742043814A SU597338A3 (ru) 1972-05-10 1974-06-17 Способ получени производных 2-бензоил-3-амино-6-галоидпиридинов или их солей
SU2043813A SU561508A3 (ru) 1972-05-10 1974-07-17 Способ получени производных 2-бензоил3-(аминоацетиламидо)-пиридина или их солей
SU742043816A SU677653A3 (ru) 1972-05-10 1974-07-17 Способ получени 2-бензоил-3аминопиридинов или их солей

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SU1914703A SU538662A3 (ru) 1972-05-10 1973-04-26 Способ получени производных 2-бензоил-3-аминопиридина или их солей
SU742043814A SU597338A3 (ru) 1972-05-10 1974-06-17 Способ получени производных 2-бензоил-3-амино-6-галоидпиридинов или их солей

Family Applications After (1)

Application Number Title Priority Date Filing Date
SU742043816A SU677653A3 (ru) 1972-05-10 1974-07-17 Способ получени 2-бензоил-3аминопиридинов или их солей

Country Status (23)

Country Link
US (1) US3875176A (ru)
JP (1) JPS4948674A (ru)
AR (2) AR207633Q (ru)
AT (1) AT321303B (ru)
AU (1) AU469111B2 (ru)
BE (1) BE799339A (ru)
CA (1) CA991189A (ru)
CH (2) CH605761A5 (ru)
CS (1) CS181238B2 (ru)
DD (1) DD106378A5 (ru)
DE (1) DE2319872A1 (ru)
EG (1) EG11137A (ru)
ES (3) ES413173A1 (ru)
FR (1) FR2184077B1 (ru)
GB (1) GB1416459A (ru)
HU (1) HU169037B (ru)
IL (1) IL42007A (ru)
NL (1) NL7306170A (ru)
PL (1) PL91935B1 (ru)
RO (1) RO63441A (ru)
SE (1) SE415974B (ru)
SU (4) SU538662A3 (ru)
ZA (1) ZA732013B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4007290A (en) * 1974-01-09 1977-02-08 General Foods Corporation Caffeine antagonim
DE3067662D1 (en) * 1980-01-16 1984-06-07 Lacer Sa New 2-halo-pyridines, their production and pharmaceutical compositions
JPH01104580U (ru) * 1988-01-05 1989-07-14
JP2531989B2 (ja) * 1988-09-14 1996-09-04 吉富製薬株式会社 ピリジン化合物
RU2255088C2 (ru) * 2001-02-09 2005-06-27 Исихара Сангио Кайся, Лтд. Производное бензоилпиридина или его соль, содержащий его в качестве активного ингредиента фунгицид, способы его получения и промежуточные соединения для его получения

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3781360A (en) * 1966-01-14 1973-12-25 Schering Corp 2-polyfluoroloweralkylamino benzophenones
US3763178A (en) * 1968-09-05 1973-10-02 American Home Prod Imidazolinyl phenyl carbonyl acid addition salts and related compounds

Also Published As

Publication number Publication date
EG11137A (en) 1978-06-30
CH582150A5 (ru) 1976-11-30
JPS4948674A (ru) 1974-05-11
AT321303B (de) 1975-03-25
FR2184077A1 (ru) 1973-12-21
SU677653A3 (ru) 1979-07-30
AR201105A1 (es) 1975-02-14
RO63441A (fr) 1978-05-15
CH605761A5 (ru) 1978-10-13
BE799339A (fr) 1973-11-09
US3875176A (en) 1975-04-01
AR207633Q (es) 1976-10-22
SE415974B (sv) 1980-11-17
HU169037B (ru) 1976-09-28
ZA732013B (en) 1974-04-24
AU469111B2 (en) 1976-02-05
IL42007A0 (en) 1973-06-29
CS181238B2 (en) 1978-03-31
NL7306170A (ru) 1973-11-13
ES413173A1 (es) 1976-01-16
GB1416459A (en) 1975-12-03
SU597338A3 (ru) 1978-03-05
IL42007A (en) 1977-06-30
CA991189A (en) 1976-06-15
PL91935B1 (ru) 1977-03-31
DE2319872A1 (de) 1973-11-22
ES413174A1 (es) 1976-01-16
ES413175A1 (es) 1976-06-01
FR2184077B1 (ru) 1976-07-02
AU5553773A (en) 1974-11-14
DD106378A5 (ru) 1974-06-12
SU538662A3 (ru) 1976-12-05

Similar Documents

Publication Publication Date Title
SU662005A3 (ru) Способ получени замещенных бензамидов или их солей
SU561508A3 (ru) Способ получени производных 2-бензоил3-(аминоацетиламидо)-пиридина или их солей
SU574146A3 (ru) Способ получени замещенных производных гидразидов -аминооксикарбоновых кислот или их солей
SU535907A3 (ru) Способ получени 1-(4-метил-6окси-2-пиримидинил)-3-метилпиразолин-5-она
US2538765A (en) Diacyl phenylpropaneaminodiols
US2943092A (en) Method of preparing 4-amino-3-isoxazolidinones
US3299095A (en) 1-benzyl tetramic acid derivatives
SU448644A3 (ru) Способ получени изоиндолиновых производных
SU485594A4 (ru) Способ получени производных 4 сульфамоил-м-толуидина
SU486503A3 (ru) Способ получени производных -фенилжирной кислоты
SU545643A1 (ru) Способ получени 4-окси-7-аминобензо-2,1,3-тиадиазола
SU417426A1 (ru)
SU560528A3 (ru) Способ получени производных аминопропанола,их солей,рацематов или оптически-активных антиподов
SU501670A3 (ru) Способ получени производных циклопентено-хинолона
SU576955A3 (ru) Способ получени производных аденозина
SU650502A3 (ru) Способ получени 4-(4"-хлорбензилокси)-бензилникотината или его солей
SU470957A3 (ru) Способ получени производных 4-аминопирролин-3-она-2 или их солей
SU419523A1 (ru) СПОСОБ ПОЛУЧЕНИЯ S-ЭФИРОВ ПИРИДИН-4-ТИО ГИДксимовой кислоты
SU554813A3 (ru) Способ получени производных тетразола или их солей
US2463941A (en) Phenacetyl amino acids
SU442595A1 (ru) Способ получени 5-(2-аминофенилсульфамоил)-4-хлор- -фурфурилантраниловой кислоты
SU510475A1 (ru) Способ получени 4-морфолинофенилалкановых кислот
SU570599A1 (ru) 1-Способ получени амидов адамантан -1- карбоновых кислот
SU436057A1 (ru) СПОСОБ ПОЛУЧЕНИЯ ИЗОПРОПИЛИДЕНОВЫХ ПРОИЗВОДНЫХ ПИРИДОКСИНАВ ПТ5ФОНЯ mmim
SU388554A1 (ru) Способ получени никотиноил- -метионина