SU219116A1 - FILM FOR PRIMARY PROCESSING OF THE BURN SURFACE - Google Patents
FILM FOR PRIMARY PROCESSING OF THE BURN SURFACEInfo
- Publication number
- SU219116A1 SU219116A1 SU1039260A SU1039260A SU219116A1 SU 219116 A1 SU219116 A1 SU 219116A1 SU 1039260 A SU1039260 A SU 1039260A SU 1039260 A SU1039260 A SU 1039260A SU 219116 A1 SU219116 A1 SU 219116A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- film
- polyvinylpyrrolidone
- glycerin
- polyvinyl alcohol
- primary processing
- Prior art date
Links
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 235000011187 glycerol Nutrition 0.000 claims description 5
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 5
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 5
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 5
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 4
- BLFLLBZGZJTVJG-UHFFFAOYSA-N benzocaine Chemical compound CCOC(=O)C1=CC=C(N)C=C1 BLFLLBZGZJTVJG-UHFFFAOYSA-N 0.000 claims description 3
- 238000004090 dissolution Methods 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 230000035699 permeability Effects 0.000 claims description 2
- 239000004014 plasticizer Substances 0.000 claims description 2
- 230000000202 analgesic effect Effects 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 238000011221 initial treatment Methods 0.000 claims 1
- 230000014759 maintenance of location Effects 0.000 claims 1
- IAIWVQXQOWNYOU-FPYGCLRLSA-N nitrofural Chemical compound NC(=O)N\N=C\C1=CC=C([N+]([O-])=O)O1 IAIWVQXQOWNYOU-FPYGCLRLSA-N 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229960001907 nitrofurazone Drugs 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
Description
Известные пленки дл первичной обработки ожоговой поверхности на основе поливинилового спирта с добавлением пластификатора - глицерина и лекарственных веществ недостаточно проницаемы дл лечебных препаратов и быстро раствор ютс в ожоговом эскудате.Known polyvinyl alcohol-based pre-treatment of a burn surface with the addition of a plasticizer — glycerin and medicinal substances — are not sufficiently permeable to medical preparations and quickly dissolve in the burn escudate.
В состав предлагаемой пленки введен поливинилпирролидон , что позвол ет увеличить ее проницаемость дл лечебных препаратов и обеспечить достаточно медленное растворение под воздействием ожогового эскудатаНаиболее быстрое обезболивающее и бактерицидное действие и хорошее удержание на поврежденной поверхности обеспечиваетс при следующем соотношении компонентов в пленке: поливиниловый спирт 81,37-81,56%, поливинилпирролидон 8,14-8,15%, глицерин 9,76-9,81%, фурациллин 0,65-0,40% и анестезин 0,08%. Содержание летучих веществ 10-25% из расчета на сухую пленку.Polyvinylpyrrolidone is introduced into the composition of the proposed film, which makes it possible to increase its permeability for medicinal preparations and to ensure a sufficiently slow dissolution under the influence of a burn escudate. 81.56%, polyvinylpyrrolidone 8.14-8.15%, glycerin 9.76-9.81%, furacilin 0.65-0.40% and anesthesin 0.08%. The content of volatile substances 10-25% based on the dry film.
Дл получени предлагаемой пленки фурациллин , анестезин, глицерин и поливинилпирролидон помещают в колбу с дистиллированной водой и выдерживают в термостате, периодически перемешива при 150°С до полного растворени . Раствор переливают в колбу с разогретым раствором поливинилового спирта, перемешивают и дополнительно прогревают при 120-150° С в течение 30 мин.To obtain the proposed film, furacillin, anestezin, glycerin and polyvinylpyrrolidone are placed in a flask with distilled water and kept in a thermostat, stirring occasionally at 150 ° C until complete dissolution. The solution is poured into a flask with a heated solution of polyvinyl alcohol, stirred, and further heated at 120-150 ° C for 30 minutes.
Полученный раствор разливают на стекла, предварительно очищенные и установленные по уровню в термостате. Высущивание производ т при 30-36° С в течение 20-24 час или при 54-60° С в течение 4-5 час. Полученную пленку толщиной 40-60 мк снимают, упаковывают вместе с наложенным полотном марли в мешочки из полиэтилена и заваривают.The resulting solution is poured into glass, pre-cleaned and installed on the level in the thermostat. Drying is performed at 30-36 ° C for 20-24 hours or at 54-60 ° C for 4-5 hours. The resulting film with a thickness of 40-60 microns is removed, packaged together with the superimposed cloth of gauze in bags of polyethylene and brewed.
Предмет изобретени Subject invention
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1039260A SU219116A1 (en) | 1965-11-26 | 1965-11-26 | FILM FOR PRIMARY PROCESSING OF THE BURN SURFACE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU1039260A SU219116A1 (en) | 1965-11-26 | 1965-11-26 | FILM FOR PRIMARY PROCESSING OF THE BURN SURFACE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU219116A1 true SU219116A1 (en) | 1973-03-20 |
Family
ID=20438873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU1039260A SU219116A1 (en) | 1965-11-26 | 1965-11-26 | FILM FOR PRIMARY PROCESSING OF THE BURN SURFACE |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU219116A1 (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1982000099A1 (en) * | 1980-07-09 | 1982-01-21 | Key Pharma | Polymeric diffusion matrix for administration of drugs |
| US4321252A (en) | 1979-08-14 | 1982-03-23 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing ester derivatives of estradiol |
| US4438139A (en) | 1979-08-14 | 1984-03-20 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing estrogens |
| US4460562A (en) * | 1982-01-06 | 1984-07-17 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing propranolol |
| US4585797A (en) * | 1981-04-13 | 1986-04-29 | Seton Company | Cosmetic and pharmaceutical sheet material containing polypeptides |
| US4591501A (en) * | 1981-04-13 | 1986-05-27 | Seton Company | Cosmetic and pharmaceutical sheet material containing polypeptides |
| RU2716158C1 (en) * | 2019-03-28 | 2020-03-06 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се | Agent for treating skin damages and method for production thereof (embodiments) |
-
1965
- 1965-11-26 SU SU1039260A patent/SU219116A1/en active
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4321252A (en) | 1979-08-14 | 1982-03-23 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing ester derivatives of estradiol |
| US4438139A (en) | 1979-08-14 | 1984-03-20 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing estrogens |
| US4466953A (en) * | 1979-08-14 | 1984-08-21 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix |
| US4470962A (en) * | 1979-08-14 | 1984-09-11 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix |
| US4492685A (en) * | 1979-08-14 | 1985-01-08 | Key Pharmaceuticals, Inc. | Protective skin matrix |
| WO1982000099A1 (en) * | 1980-07-09 | 1982-01-21 | Key Pharma | Polymeric diffusion matrix for administration of drugs |
| US4585797A (en) * | 1981-04-13 | 1986-04-29 | Seton Company | Cosmetic and pharmaceutical sheet material containing polypeptides |
| US4591501A (en) * | 1981-04-13 | 1986-05-27 | Seton Company | Cosmetic and pharmaceutical sheet material containing polypeptides |
| US4460562A (en) * | 1982-01-06 | 1984-07-17 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing propranolol |
| RU2716158C1 (en) * | 2019-03-28 | 2020-03-06 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се | Agent for treating skin damages and method for production thereof (embodiments) |
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