SMT202000018T1 - Angiotensina ii in combinazione per il trattamento dell’ipotensione - Google Patents

Angiotensina ii in combinazione per il trattamento dell’ipotensione

Info

Publication number: SMT202000018T1
Authority: SM; San Marino
Prior art keywords: hypotension; angiotensin; treatment; combination
Prior art date: 2013-12-18

Application number

SM20200018T

Other languages

English (en)

Inventor

Lakhmir Chawla

Original Assignee

The George Washington University A Congressionally Chartered Not For Profit Corporation

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-12-18

Filing date

2014-12-18

Publication date

2020-03-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53367119&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT202000018(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-12-18 Application filed by The George Washington University A Congressionally Chartered Not For Profit Corporation filed Critical The George Washington University A Congressionally Chartered Not For Profit Corporation

2020-03-13 Publication of SMT202000018T1 publication Critical patent/SMT202000018T1/it

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Vascular Medicine (AREA)
Emergency Medicine (AREA)
Dermatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SM20200018T 2013-12-18 2014-12-18 Angiotensina ii in combinazione per il trattamento dell’ipotensione SMT202000018T1 (it)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201361917576P	2013-12-18	2013-12-18
US201461955706P	2014-03-19	2014-03-19
PCT/US2014/071186 WO2015095535A1 (en)	2013-12-18	2014-12-18	Angiotensin ii alone or in combination for the treatment of hypotension
EP14872684.7A EP2986308B1 (en)	2013-12-18	2014-12-18	Angiotensin ii in combination for the treatment of hypotension

Publications (1)

Publication Number	Publication Date
SMT202000018T1 true SMT202000018T1 (it)	2020-03-13

Family

ID=53367119

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SM20200018T SMT202000018T1 (it)	2013-12-18	2014-12-18	Angiotensina ii in combinazione per il trattamento dell’ipotensione
SM20250427T SMT202500427T1 (it)	2013-12-18	2014-12-18	Angiotensina ii da sola o in combinazione per il trattamento dell’ipotensione

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SM20250427T SMT202500427T1 (it)	2013-12-18	2014-12-18	Angiotensina ii da sola o in combinazione per il trattamento dell’ipotensione

Country Status (25)

Country	Link
US (7)	US9220745B2 (it)
EP (2)	EP3607962B1 (it)
JP (4)	JP6824739B2 (it)
KR (4)	KR20220028125A (it)
CN (4)	CN111920939A (it)
AU (3)	AU2014364528C1 (it)
BR (1)	BR112016013961A2 (it)
CA (1)	CA2933601A1 (it)
CY (1)	CY1122604T1 (it)
DK (2)	DK3607962T3 (it)
EA (1)	EA037823B1 (it)
ES (1)	ES2771749T3 (it)
FI (1)	FI3607962T3 (it)
HR (1)	HRP20200009T1 (it)
HU (1)	HUE047062T2 (it)
IL (1)	IL246162B (it)
LT (2)	LT2986308T (it)
MX (2)	MX380968B (it)
NZ (1)	NZ721089A (it)
PL (1)	PL2986308T3 (it)
PT (2)	PT2986308T (it)
RS (1)	RS59804B1 (it)
SI (1)	SI2986308T1 (it)
SM (2)	SMT202000018T1 (it)
WO (1)	WO2015095535A1 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9572856B2 (en)	2009-12-16	2017-02-21	The George Washington University a Congressionally Chartered Not-for-Profit Corporation	Method of treating low blood pressure
WO2015095535A1 (en)	2013-12-18	2015-06-25	The George Washington University, A Congressional Chartered Not-For-Profit Corporation	Angiotensin ii alone or in combination for the treatment of hypotension
JP2017519799A (ja) *	2014-07-08	2017-07-20	ラホヤファーマシューティカルカンパニーＬａＪｏｌｌａＰｈａｒｍａｃｅｕｔｉｃａｌＣｏｍｐａｎｙ	低血圧の治療方法
WO2016153558A1 (en)	2015-03-20	2016-09-29	Atkinson Arthur J	Use of angiotensin ii (aii) receptor agonists to prevent or reduce hemodialysis-associated skeletal muscle cramps
CA3010781A1 (en)	2016-01-07	2017-07-13	La Jolla Pharmaceutical Company	Methods for administering angiotensin ii
TW201735913A (zh) *	2016-01-07	2017-10-16	拉荷亞製藥公司	投與血管加壓劑之方法
WO2018191678A1 (en) *	2017-04-14	2018-10-18	La Jolla Pharmaceutical Company	Methods for administering angiotensin ii
TW201927331A (zh) *	2017-12-15	2019-07-16	美商拉荷亞製藥公司	血管收縮素組合物及與其相關之方法
US20250366467A1 (en) *	2022-06-15	2025-12-04	Virginia Commonwealth University	Methods for fluid resuscitation of an organ donor
WO2024129057A1 (en) *	2022-12-12	2024-06-20	Proletariat Therapeutics, Inc.	Methods of treating cardiac injury

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HU181008B (en)	1980-01-18	1983-05-30	Richter Gedeon Vegyeszet	Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position
US5216025A (en) *	1989-09-13	1993-06-01	Board Of Regents, The University Of Texas System	Nitric oxide synthesis inhibitors for potentiating the action of pressor agents in certain hypotensive patients
US5444067A (en)	1993-08-30	1995-08-22	Merck & Co., Inc.	Pharmaceutical treatment methods using angiotensin II receptor agonists bearing a thiophene moiety
US6592865B2 (en)	2001-06-04	2003-07-15	Human Genome Sciences, Inc.	Methods and compositions for modulating ACE-2 activity
US7115266B2 (en)	2001-10-05	2006-10-03	Cytos Biotechnology Ag	Angiotensin peptide-carrier conjugates and uses thereof
EP1699495A2 (en)	2003-11-06	2006-09-13	Amersham Health AS	Conjugates of angiotensin ii and an imaging moiety
NO20034952D0 (no)	2003-11-06	2003-11-06	Amersham Health As	Farmasöytiske forbindelser
FR2880807B1 (fr) *	2005-01-19	2007-04-13	Aguettant Sa Lab	Composition pharmaceutique injectable
DE602006021600D1 (de)	2005-09-29	2011-06-09	Fibrogen Inc	Verfahren zur senkung des blutdrucks
CA2633013A1 (en) *	2005-12-30	2007-07-12	Howard Florey Institute Of Experimental Physiology And Medicine	A method of treatment
WO2007146900A2 (en)	2006-06-15	2007-12-21	Gilead Colorado, Inc.	Antihypertensive therapy method
WO2008130217A1 (en) *	2006-08-08	2008-10-30	Applied Nanosystems B.V.	Cyclic angiotensin analogs
AU2007321111A1 (en)	2006-11-17	2008-05-22	Da Volterra	Colonic delivery using Zn/pectin beads with a Eudragit coating.
WO2009009907A1 (en) *	2007-07-18	2009-01-22	The University Of British Columbia	Use of vasopressin-receptor agonists for the treatment of septic shock
EP2161030A1 (en) *	2008-09-09	2010-03-10	Rijksuniversiteit te Groningen	Oxytocin formulations and uses thereof
CA2742791A1 (en)	2008-11-28	2010-06-03	Abbott Laboratories	Stable antibody compositions and methods for stabilizing same
US9572856B2 (en)	2009-12-16	2017-02-21	The George Washington University a Congressionally Chartered Not-for-Profit Corporation	Method of treating low blood pressure
FR2959414B1 (fr) *	2010-04-30	2016-01-08	Luc Quintin	Combinaison de molecules aux fins de traitement d'hypotension survenant au cours du choc septique, cardiogenique, ou anaphylactique refractaire, ou hemorragique terminal, apres correction de la volemie et de l'etat de mal asthmatique refractaire
EP2593541A4 (en)	2010-07-14	2014-01-22	Cumberland Emerging Technologies Inc	METHOD FOR THE TREATMENT OF HEPATORENAL SYNDROME AND HEPATIC ENZEPHALOPATHY WITH THROMBOXANE A2 RECEPTOR ANTAGONISTS
CN105592855A (zh)	2013-04-26	2016-05-18	拉卓拉药物公司	用于治疗肾衰竭的组合物和方法
WO2015095535A1 (en)	2013-12-18	2015-06-25	The George Washington University, A Congressional Chartered Not-For-Profit Corporation	Angiotensin ii alone or in combination for the treatment of hypotension
US20150286797A1 (en)	2014-04-02	2015-10-08	David R. Ratto	System and method for administering medication
JP2017519799A (ja)	2014-07-08	2017-07-20	ラホヤファーマシューティカルカンパニーＬａＪｏｌｌａＰｈａｒｍａｃｅｕｔｉｃａｌＣｏｍｐａｎｙ	低血圧の治療方法
TW201735913A (zh)	2016-01-07	2017-10-16	拉荷亞製藥公司	投與血管加壓劑之方法
CA3010781A1 (en)	2016-01-07	2017-07-13	La Jolla Pharmaceutical Company	Methods for administering angiotensin ii
WO2018191678A1 (en)	2017-04-14	2018-10-18	La Jolla Pharmaceutical Company	Methods for administering angiotensin ii
TW201927331A (zh)	2017-12-15	2019-07-16	美商拉荷亞製藥公司	血管收縮素組合物及與其相關之方法

2014
- 2014-12-18 WO PCT/US2014/071186 patent/WO2015095535A1/en not_active Ceased
- 2014-12-18 CN CN202010824424.5A patent/CN111920939A/zh active Pending
- 2014-12-18 LT LTEP14872684.7T patent/LT2986308T/lt unknown
- 2014-12-18 HU HUE14872684A patent/HUE047062T2/hu unknown
- 2014-12-18 MX MX2016008108A patent/MX380968B/es unknown
- 2014-12-18 PT PT148726847T patent/PT2986308T/pt unknown
- 2014-12-18 CN CN202411722811.2A patent/CN119700926A/zh active Pending
- 2014-12-18 NZ NZ721089A patent/NZ721089A/en unknown
- 2014-12-18 SM SM20200018T patent/SMT202000018T1/it unknown
- 2014-12-18 US US14/575,127 patent/US9220745B2/en active Active
- 2014-12-18 BR BR112016013961A patent/BR112016013961A2/pt not_active Application Discontinuation
- 2014-12-18 EP EP19197866.7A patent/EP3607962B1/en active Active
- 2014-12-18 JP JP2016539318A patent/JP6824739B2/ja active Active
- 2014-12-18 DK DK19197866.7T patent/DK3607962T3/da active
- 2014-12-18 KR KR1020227004084A patent/KR20220028125A/ko not_active Ceased
- 2014-12-18 PL PL14872684T patent/PL2986308T3/pl unknown
- 2014-12-18 LT LTEP19197866.7T patent/LT3607962T/lt unknown
- 2014-12-18 KR KR1020237012136A patent/KR20230051721A/ko not_active Ceased
- 2014-12-18 HR HRP20200009TT patent/HRP20200009T1/hr unknown
- 2014-12-18 FI FIEP19197866.7T patent/FI3607962T3/fi active
- 2014-12-18 ES ES14872684T patent/ES2771749T3/es active Active
- 2014-12-18 EA EA201691258A patent/EA037823B1/ru unknown
- 2014-12-18 CN CN201480075899.1A patent/CN106061493A/zh active Pending
- 2014-12-18 DK DK14872684.7T patent/DK2986308T3/da active
- 2014-12-18 SI SI201431450T patent/SI2986308T1/sl unknown
- 2014-12-18 EP EP14872684.7A patent/EP2986308B1/en active Active
- 2014-12-18 PT PT191978667T patent/PT3607962T/pt unknown
- 2014-12-18 AU AU2014364528A patent/AU2014364528C1/en active Active
- 2014-12-18 KR KR1020247034828A patent/KR20240154702A/ko active Pending
- 2014-12-18 SM SM20250427T patent/SMT202500427T1/it unknown
- 2014-12-18 CA CA2933601A patent/CA2933601A1/en active Pending
- 2014-12-18 CN CN202011494632.XA patent/CN112546197A/zh active Pending
- 2014-12-18 RS RS20200021A patent/RS59804B1/sr unknown
- 2014-12-18 KR KR1020167019427A patent/KR102399383B1/ko active Active
2015
- 2015-11-13 US US14/941,301 patent/US10028995B2/en active Active
2016
- 2016-06-09 IL IL246162A patent/IL246162B/en active IP Right Grant
- 2016-06-17 MX MX2020011190A patent/MX2020011190A/es unknown
2018
- 2018-03-01 US US15/909,617 patent/US10493124B2/en active Active
- 2018-09-19 US US16/135,608 patent/US10765722B2/en active Active
2019
- 2019-04-12 US US16/382,850 patent/US11096983B2/en active Active
- 2019-08-23 JP JP2019153144A patent/JP7175506B2/ja active Active
2020
- 2020-01-13 CY CY20201100026T patent/CY1122604T1/el unknown
- 2020-11-26 AU AU2020277230A patent/AU2020277230A1/en not_active Abandoned
2021
- 2021-07-20 US US17/380,311 patent/US11559559B2/en active Active
2022
- 2022-07-14 JP JP2022113327A patent/JP2022137224A/ja not_active Withdrawn
2023
- 2023-01-23 US US18/157,933 patent/US20230226141A1/en not_active Abandoned
2024
- 2024-09-18 AU AU2024219851A patent/AU2024219851A1/en active Pending
2025
- 2025-05-09 JP JP2025078759A patent/JP2025114753A/ja active Pending

Also Published As

Publication number	Publication date
JP2025114753A (ja)	2025-08-05
JP2017501154A (ja)	2017-01-12
HRP20200009T1 (hr)	2020-03-20
JP7175506B2 (ja)	2022-11-21
PL2986308T3 (pl)	2020-05-18
KR20220028125A (ko)	2022-03-08
KR20230051721A (ko)	2023-04-18
US11096983B2 (en)	2021-08-24
RS59804B1 (sr)	2020-02-28
US20190070250A1 (en)	2019-03-07
MX2020011190A (es)	2020-11-13
LT3607962T (lt)	2026-01-12
IL246162A0 (en)	2016-07-31
CN111920939A (zh)	2020-11-13
WO2015095535A9 (en)	2016-07-14
SMT202500427T1 (it)	2026-01-12
US9220745B2 (en)	2015-12-29
US20160129072A1 (en)	2016-05-12
CA2933601A1 (en)	2015-06-25
AU2014364528A1 (en)	2016-06-30
CN119700926A (zh)	2025-03-28
ES2771749T3 (es)	2020-07-07
BR112016013961A2 (pt)	2017-10-10
US20190328827A1 (en)	2019-10-31
LT2986308T (lt)	2020-03-25
US20180193407A1 (en)	2018-07-12
SI2986308T1 (sl)	2020-03-31
KR20240154702A (ko)	2024-10-25
EP2986308A4 (en)	2017-01-11
KR20160117437A (ko)	2016-10-10
PT2986308T (pt)	2020-01-21
US20150164980A1 (en)	2015-06-18
NZ721089A (en)	2022-10-28
DK3607962T3 (da)	2025-11-17
US11559559B2 (en)	2023-01-24
HUE047062T2 (hu)	2020-04-28
MX2016008108A (es)	2017-03-09
US20230226141A1 (en)	2023-07-20
CN106061493A (zh)	2016-10-26
US10765722B2 (en)	2020-09-08
EP3607962B1 (en)	2025-08-13
AU2014364528C1 (en)	2021-01-07
JP6824739B2 (ja)	2021-02-03
MX380968B (es)	2025-03-12
KR102399383B1 (ko)	2022-05-19
US10028995B2 (en)	2018-07-24
JP2022137224A (ja)	2022-09-21
CN112546197A (zh)	2021-03-26
DK2986308T3 (en)	2020-01-27
CY1122604T1 (el)	2021-03-12
AU2020277230A1 (en)	2020-12-24
EA037823B1 (ru)	2021-05-25
US10493124B2 (en)	2019-12-03
AU2024219851A1 (en)	2024-10-10
US20220047669A1 (en)	2022-02-17
EP2986308A1 (en)	2016-02-24
EP3607962A1 (en)	2020-02-12
AU2014364528B2 (en)	2020-08-27
WO2015095535A1 (en)	2015-06-25
PT3607962T (pt)	2025-11-18
EA201691258A1 (ru)	2016-11-30
FI3607962T3 (fi)	2025-11-24
IL246162B (en)	2020-03-31
JP2019214610A (ja)	2019-12-19
AU2014364528A9 (en)	2016-07-28
EP2986308B1 (en)	2019-10-16

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GB201321743D0 (en)	2014-01-22	Therapeutic agents
GB201321746D0 (en)	2014-01-22	Therapeutic agents
GB201321738D0 (en)	2014-01-22	Therapeutic Agents
GB201321736D0 (en)	2014-01-22	Therapeutic agents
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GB201321730D0 (en)	2014-01-22	Therapeutic agents
GB201321740D0 (en)	2014-01-22	Therapeutic agents
IL246162A0 (en)	2016-07-31	Angiotensin II, alone or in combination, to treat low blood pressure
GB201321734D0 (en)	2014-01-22	Therapeutic Agents
GB201321732D0 (en)	2014-01-22	Therapeutic agents
GB201321744D0 (en)	2014-01-22	Therapeutic agents
GB201321737D0 (en)	2014-01-22	Therapeutic Agents
GB201321742D0 (en)	2014-01-22	Therapeutic agents
GB201321735D0 (en)	2014-01-22	Therapeutic Agents
GB201321745D0 (en)	2014-01-22	Therapeutic agents
GB201321731D0 (en)	2014-01-22	Therapeutic agents
GB201304872D0 (en)	2013-05-01	Treatment
GB201317960D0 (en)	2013-11-27	Water treatment
GB201302839D0 (en)	2013-04-03	Water Treatment