SMT201300092B - Un procedimento per produrre crema di acido fusidico - Google Patents
Un procedimento per produrre crema di acido fusidicoInfo
- Publication number
- SMT201300092B SMT201300092B SM201300092T SM201300092T SMT201300092B SM T201300092 B SMT201300092 B SM T201300092B SM 201300092 T SM201300092 T SM 201300092T SM 201300092 T SM201300092 T SM 201300092T SM T201300092 B SMT201300092 B SM T201300092B
- Authority
- SM
- San Marino
- Prior art keywords
- fusidic acid
- cream
- present
- sodium fusidate
- api
- Prior art date
Links
- 229960004675 fusidic acid Drugs 0.000 title abstract 8
- IECPWNUMDGFDKC-MZJAQBGESA-N fusidic acid Chemical compound O[C@@H]([C@@H]12)C[C@H]3\C(=C(/CCC=C(C)C)C(O)=O)[C@@H](OC(C)=O)C[C@]3(C)[C@@]2(C)CC[C@@H]2[C@]1(C)CC[C@@H](O)[C@H]2C IECPWNUMDGFDKC-MZJAQBGESA-N 0.000 title abstract 8
- 239000006071 cream Substances 0.000 title abstract 7
- IECPWNUMDGFDKC-UHFFFAOYSA-N Fusicsaeure Natural products C12C(O)CC3C(=C(CCC=C(C)C)C(O)=O)C(OC(C)=O)CC3(C)C1(C)CCC1C2(C)CCC(O)C1C IECPWNUMDGFDKC-UHFFFAOYSA-N 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 239000008186 active pharmaceutical agent Substances 0.000 abstract 2
- 238000011065 in-situ storage Methods 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000006708 antioxidants Nutrition 0.000 abstract 1
- 239000006172 buffering agent Substances 0.000 abstract 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 239000011261 inert gas Substances 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000008213 purified water Substances 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN358MU2009 | 2009-02-18 | ||
| PCT/IB2010/050685 WO2010095091A1 (en) | 2009-02-18 | 2010-02-16 | A process to make fusidic acid cream |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201300092B true SMT201300092B (it) | 2013-11-08 |
Family
ID=42338153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201300092T SMT201300092B (it) | 2009-02-18 | 2013-08-16 | Un procedimento per produrre crema di acido fusidico |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8748640B2 (xx) |
| EP (1) | EP2403480B1 (xx) |
| JP (1) | JP5702308B2 (xx) |
| KR (1) | KR101680399B1 (xx) |
| CN (1) | CN102325524B (xx) |
| BR (1) | BRPI1005922B1 (xx) |
| CY (1) | CY1114021T1 (xx) |
| DK (1) | DK2403480T3 (xx) |
| ES (1) | ES2423231T3 (xx) |
| HR (1) | HRP20130515T1 (xx) |
| IL (1) | IL214709A (xx) |
| PL (1) | PL2403480T3 (xx) |
| PT (1) | PT2403480E (xx) |
| RU (1) | RU2536426C2 (xx) |
| SI (1) | SI2403480T1 (xx) |
| SM (1) | SMT201300092B (xx) |
| WO (1) | WO2010095091A1 (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8895542B2 (en) * | 2009-04-13 | 2014-11-25 | Vanangamudi Subramaniam Sulur | Medicinal fusidic acid cream made using sodium fusidate and incorporating a biopolymer and a process to make it |
| WO2012162439A2 (en) * | 2011-05-23 | 2012-11-29 | Cem-102 Pharmaceuticals, Inc. | Compositions comprising fusidic acid and packages therefor |
| CN115721602B (zh) * | 2022-10-25 | 2025-05-16 | 华东医药(西安)博华制药有限公司 | 一种夫西地酸乳膏及其制备方法和应用 |
| CN115887355B (zh) * | 2022-11-18 | 2024-11-15 | 南京康川济医药科技有限公司 | 一种克立硼罗乳膏及其制备方法 |
| CN116650399B (zh) * | 2023-04-13 | 2025-09-05 | 福元药业有限公司 | 一种夫西地酸乳膏及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8500310D0 (en) * | 1985-01-07 | 1985-02-13 | Leo Pharm Prod Ltd | Pharmaceutical preparation |
| ES2204331B1 (es) * | 2002-10-09 | 2005-03-01 | Ercros Industrial, S.A. | Procedimiento para la obtencion de acido fusidico a partir de un caldo de fermentacion. |
| RU2240781C1 (ru) * | 2003-06-05 | 2004-11-27 | Уральский научно-исследовательский институт дерматовенерологии и иммунопатологии | Способ лечения воспалительных процессов вульвы и влагалища |
| BRPI0707367A2 (pt) * | 2006-02-02 | 2011-05-03 | Leo Pharma As | composição farmacêutica, uso de uma composição, e, método de prevenir ou tratar uma doença dérmica ou condição da pele ou mucosa |
| US9132071B2 (en) * | 2006-07-28 | 2015-09-15 | Santen Sas | Compositions containing quaternary ammonium compounds |
| RU2536252C2 (ru) * | 2008-12-19 | 2014-12-20 | Сулур Субраманиам ВАНАНГАМУДИ | Новый дерматологический крем, изготовленный с использованием фусидата натрия |
-
2010
- 2010-02-16 PT PT107201980T patent/PT2403480E/pt unknown
- 2010-02-16 HR HRP20130515AT patent/HRP20130515T1/hr unknown
- 2010-02-16 KR KR1020117021900A patent/KR101680399B1/ko active Active
- 2010-02-16 BR BRPI1005922-9A patent/BRPI1005922B1/pt active IP Right Grant
- 2010-02-16 DK DK10720198.0T patent/DK2403480T3/da active
- 2010-02-16 WO PCT/IB2010/050685 patent/WO2010095091A1/en not_active Ceased
- 2010-02-16 RU RU2011139043/15A patent/RU2536426C2/ru active
- 2010-02-16 US US13/201,627 patent/US8748640B2/en active Active
- 2010-02-16 CN CN2010800084401A patent/CN102325524B/zh active Active
- 2010-02-16 SI SI201030241T patent/SI2403480T1/sl unknown
- 2010-02-16 ES ES10720198T patent/ES2423231T3/es active Active
- 2010-02-16 EP EP10720198A patent/EP2403480B1/en active Active
- 2010-02-16 PL PL10720198T patent/PL2403480T3/pl unknown
- 2010-02-16 JP JP2011549724A patent/JP5702308B2/ja active Active
-
2011
- 2011-08-17 IL IL214709A patent/IL214709A/en active IP Right Grant
-
2013
- 2013-06-05 CY CY20131100446T patent/CY1114021T1/el unknown
- 2013-08-16 SM SM201300092T patent/SMT201300092B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT2403480E (pt) | 2013-07-09 |
| IL214709A0 (en) | 2011-11-30 |
| CN102325524A (zh) | 2012-01-18 |
| PL2403480T3 (pl) | 2013-08-30 |
| WO2010095091A1 (en) | 2010-08-26 |
| RU2536426C2 (ru) | 2014-12-20 |
| CN102325524B (zh) | 2013-10-09 |
| HRP20130515T1 (xx) | 2013-07-31 |
| US20110301138A1 (en) | 2011-12-08 |
| KR101680399B1 (ko) | 2016-11-28 |
| ES2423231T3 (es) | 2013-09-18 |
| RU2011139043A (ru) | 2013-06-10 |
| EP2403480A1 (en) | 2012-01-11 |
| JP2012517996A (ja) | 2012-08-09 |
| DK2403480T3 (da) | 2013-06-10 |
| KR20110138352A (ko) | 2011-12-27 |
| CY1114021T1 (el) | 2016-07-27 |
| BRPI1005922B1 (pt) | 2021-07-20 |
| US8748640B2 (en) | 2014-06-10 |
| BRPI1005922A2 (pt) | 2020-07-21 |
| JP5702308B2 (ja) | 2015-04-15 |
| EP2403480B1 (en) | 2013-04-03 |
| IL214709A (en) | 2015-10-29 |
| SI2403480T1 (sl) | 2013-07-31 |
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