SK13532000A3 - Bicyklo [2.2.1] heptány a príbuzné zlúčeniny, farmaceutické kompozície a spôsoby liečenia na ich báze - Google Patents
Bicyklo [2.2.1] heptány a príbuzné zlúčeniny, farmaceutické kompozície a spôsoby liečenia na ich báze Download PDFInfo
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- SK13532000A3 SK13532000A3 SK1353-2000A SK13532000A SK13532000A3 SK 13532000 A3 SK13532000 A3 SK 13532000A3 SK 13532000 A SK13532000 A SK 13532000A SK 13532000 A3 SK13532000 A3 SK 13532000A3
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Addiction (AREA)
- Otolaryngology (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7834698P | 1998-03-17 | 1998-03-17 | |
| PCT/IB1999/000376 WO1999047490A1 (en) | 1998-03-17 | 1999-03-04 | Bicyclo[2.2.1]heptanes and related compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK13532000A3 true SK13532000A3 (sk) | 2002-07-02 |
Family
ID=22143450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1353-2000A SK13532000A3 (sk) | 1998-03-17 | 1999-03-04 | Bicyklo [2.2.1] heptány a príbuzné zlúčeniny, farmaceutické kompozície a spôsoby liečenia na ich báze |
Country Status (40)
| Country | Link |
|---|---|
| US (1) | US6136861A (zh) |
| EP (1) | EP1064256B1 (zh) |
| JP (1) | JP3665567B2 (zh) |
| KR (1) | KR100372981B1 (zh) |
| CN (1) | CN1231461C (zh) |
| AP (1) | AP1116A (zh) |
| AR (1) | AR017236A1 (zh) |
| AT (1) | ATE272608T1 (zh) |
| AU (1) | AU753422B2 (zh) |
| BG (1) | BG104837A (zh) |
| BR (1) | BR9908850A (zh) |
| CA (1) | CA2321639C (zh) |
| CO (1) | CO5090835A1 (zh) |
| CZ (1) | CZ20003355A3 (zh) |
| DE (1) | DE69919142T2 (zh) |
| DZ (1) | DZ2745A1 (zh) |
| EA (1) | EA003946B1 (zh) |
| ES (1) | ES2224604T3 (zh) |
| GT (1) | GT199900040A (zh) |
| HR (1) | HRP20000611A2 (zh) |
| HU (1) | HUP0101031A3 (zh) |
| ID (1) | ID25651A (zh) |
| IL (1) | IL138342A0 (zh) |
| IS (1) | IS5592A (zh) |
| MA (1) | MA26614A1 (zh) |
| MY (1) | MY121047A (zh) |
| NO (1) | NO20004626L (zh) |
| NZ (1) | NZ506227A (zh) |
| OA (1) | OA11488A (zh) |
| PE (1) | PE20000339A1 (zh) |
| PL (1) | PL343278A1 (zh) |
| PT (1) | PT1064256E (zh) |
| SK (1) | SK13532000A3 (zh) |
| TN (1) | TNSN99039A1 (zh) |
| TR (1) | TR200002671T2 (zh) |
| TW (1) | TW509667B (zh) |
| UA (1) | UA53781C2 (zh) |
| WO (1) | WO1999047490A1 (zh) |
| YU (1) | YU53700A (zh) |
| ZA (1) | ZA992094B (zh) |
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|---|---|---|---|---|
| US6555564B1 (en) * | 1999-03-04 | 2003-04-29 | The Board Of Trustees Of The University Of Illinois | Neuropharmacological treatments of sleep-related breathing disorders |
| US6313159B1 (en) | 1999-08-20 | 2001-11-06 | Guilford Pharmaceuticals Inc. | Metabotropic glutamate receptor ligand derivatives as naaladase inhibitors |
| UA73981C2 (en) * | 2000-03-10 | 2005-10-17 | Merck Patent Gmbh | (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit |
| EP1372620A2 (en) * | 2001-03-15 | 2004-01-02 | Saegis Pharmaceuticals | Methods for restoring cognitive function following systemic stress |
| US6750364B2 (en) | 2001-06-29 | 2004-06-15 | Wyeth | Bridged tricyclic analogs of 2-(carboxycyclopropyl)glycine as inhibitors of glutamate transport |
| US6689904B2 (en) | 2001-06-29 | 2004-02-10 | Wyeth | Bridged tricyclic analogs of 2-(carboxycyclopropyl)glycine |
| US6689905B2 (en) | 2001-06-29 | 2004-02-10 | Wyeth | Stereoisomers of 3-aminotricyclo[2.2.1.0(2.6)]heptane-1,3-dicarboxylic acid |
| US6562816B2 (en) | 2001-08-24 | 2003-05-13 | Pharmacia & Upjohn Company | Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease |
| US7232798B2 (en) * | 2001-11-13 | 2007-06-19 | Tran Loi H | Neuroprotection and neuroegenisis by administering cyclic prolyl glycine |
| FR2872045B1 (fr) * | 2004-06-28 | 2006-09-29 | Centre Nat Rech Scient Cnrse | Medicaments pour le traitement specifique de symptomes de la maladie de parkinson |
| AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
| TW200845978A (en) * | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| US8822498B2 (en) | 2007-09-13 | 2014-09-02 | Concert Pharmaceuticals, Inc. | Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof |
| BRPI0816767B8 (pt) | 2007-09-14 | 2021-05-25 | Addex Pharmaceuticals Sa | composto 4-fenil-3,4,5,6-tetra-hidro-2h,1'h-[1,4']bipiridi¬nil-2'-onas 1',3'-dissubstituídas, composição farmacêutica e uso dos mesmos |
| ES2365966T3 (es) | 2007-09-14 | 2011-10-14 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 4-(aril-x-fenil)-1h-piridin-2-onas 1,3-disustituidas. |
| WO2009033703A1 (en) * | 2007-09-14 | 2009-03-19 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 1,3-disubstituted-4-phenyl-1 h-pyridin-2-ones |
| ES2637794T3 (es) * | 2007-11-14 | 2017-10-17 | Janssen Pharmaceuticals, Inc. | Derivados de imidazo[1,2-A]piridina y su uso como moduladores alostéricos positivos de receptores MGLUR2 |
| JP5547194B2 (ja) | 2008-09-02 | 2014-07-09 | ジャンセン ファーマシューティカルズ， インコーポレイテッド． | 代謝型グルタミン酸受容体の調節因子としての３−アザビシクロ［３．１．０］ヘキシル誘導体 |
| BRPI0920354A2 (pt) | 2008-10-16 | 2017-06-27 | Addex Pharmaceuticals Sa | derivados de indol e benzomorfolina como moduladores de receptores de glutamato metabotrópicos |
| CN102232074B (zh) | 2008-11-28 | 2014-12-03 | 奥梅-杨森制药有限公司 | 作为代谢性谷氨酸盐受体调节剂的吲哚和苯并噁嗪衍生物 |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| BRPI1010831A2 (pt) | 2009-05-12 | 2016-04-05 | Addex Pharmaceuticals Sa | derivados de 1,2,4-triazolo[4,3-a]piridina e seu como moduladores alostéricos positivos de receptores de mglur2 |
| SG176021A1 (en) | 2009-05-12 | 2011-12-29 | Janssen Pharmaceuticals Inc | 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment or prevention of neurological and psychiatric disorders |
| CN103261195B (zh) | 2010-11-08 | 2015-09-02 | 杨森制药公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
| PT2649069E (pt) | 2010-11-08 | 2015-11-20 | Janssen Pharmaceuticals Inc | Derivados de 1,2,4-triazolo[4,3-a]piridina e sua utilização como moduladores alostéricos positivos de recetores mglur2 |
| AU2011328203B2 (en) | 2010-11-08 | 2015-03-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
| BR112013012384A2 (pt) | 2010-11-18 | 2019-09-24 | Lilly Co Eli | compostos 3-benzilóóxi-biciclo[3.1.0]hexano 4-substituídos como antagonistas receptores de mglu2 e mglu3 |
| TWI520935B (zh) * | 2010-11-18 | 2016-02-11 | 美國禮來大藥廠 | 作為ｍＧｌｕＲ２／３拮抗劑之４－經取代－３－苯基磺醯基甲基－雙環［３.１.０］己烷化合物 |
| TWI630194B (zh) | 2013-03-14 | 2018-07-21 | 凱立拉製藥公司 | 雙環止痛化合物 |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| EP3080072A4 (en) | 2013-12-12 | 2017-07-19 | Kalyra Pharmaceuticals, inc. | Bicyclic alkyl compounds and synthesis |
| HUE045610T2 (hu) | 2014-01-21 | 2020-01-28 | Janssen Pharmaceutica Nv | 2-es altípusú metabotróp glutamáterg receptor pozitív allosztérikus modulátorait vagy ortosztérikus agonistáit tartalmazó kombinációk és alkalmazásuk |
| PH12021552653A1 (en) | 2014-01-21 | 2023-07-17 | Janssen Pharmaceutica Nv | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use |
| WO2015134710A1 (en) | 2014-03-07 | 2015-09-11 | Kalyra Pharmaceuticals, Inc. | Propellane derivates and synthesis |
| US10308609B2 (en) | 2014-09-17 | 2019-06-04 | Zeno Royalties & Milestones, LLC | Bicyclic compounds |
| US20190060257A1 (en) * | 2016-03-16 | 2019-02-28 | Zeno Royalties & Milestones, LLC | Analgesic compounds |
| WO2018213140A1 (en) | 2017-05-15 | 2018-11-22 | Zeno Royalties & Milestones, LLC | Analgesic compounds |
| GB202015788D0 (en) | 2018-05-15 | 2020-11-18 | Tran Lloyd Hung Loi | Therapeutic agent composition and method of use, for treatment of mild cognitive impairment, depression, and psychological disorders |
| KR102157141B1 (ko) | 2018-11-27 | 2020-09-17 | 주식회사 파미니티 | 으아리 추출물을 유효 성분으로 포함하는 인지 기능 개선용 조성물 |
| KR102172916B1 (ko) | 2018-12-07 | 2020-11-02 | 주식회사 파미니티 | 실크 펩타이드 및 천연 추출물을 포함하는 인지 기능 개선용 조성물 |
| US10844380B1 (en) | 2019-06-17 | 2020-11-24 | Biorchestra Co., Ltd. | Uses for prevention or treatment of brain diseases using microrna |
| US11198908B2 (en) | 2019-06-17 | 2021-12-14 | Biorchestra Co., Ltd. | Method for diagnosis of Alzheimer's disease using microRNA |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0762877T3 (da) * | 1994-06-03 | 2001-07-16 | Thejmde Trust | Meta-substituerede arylalkylaminer og terapeutiske og diagnostiske anvendelser deraf |
| PL182285B1 (pl) * | 1994-08-12 | 2001-12-31 | Lilly Co Eli | Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL |
| WO1997017950A1 (en) * | 1995-11-16 | 1997-05-22 | Eli Lilly And Company | Shoulder prosthesis |
| GB9605429D0 (en) * | 1995-11-16 | 1996-05-15 | Lilly Co Eli | Excitatory amino acid receptor antagonists |
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1999
- 1999-03-04 DE DE69919142T patent/DE69919142T2/de not_active Expired - Fee Related
- 1999-03-04 YU YU53700A patent/YU53700A/sh unknown
- 1999-03-04 IL IL13834299A patent/IL138342A0/xx unknown
- 1999-03-04 PT PT99905122T patent/PT1064256E/pt unknown
- 1999-03-04 HR HR20000611A patent/HRP20000611A2/hr not_active Application Discontinuation
- 1999-03-04 US US09/380,727 patent/US6136861A/en not_active Expired - Fee Related
- 1999-03-04 NZ NZ506227A patent/NZ506227A/xx unknown
- 1999-03-04 AT AT99905122T patent/ATE272608T1/de not_active IP Right Cessation
- 1999-03-04 PL PL99343278A patent/PL343278A1/xx unknown
- 1999-03-04 JP JP2000536687A patent/JP3665567B2/ja not_active Expired - Fee Related
- 1999-03-04 CZ CZ20003355A patent/CZ20003355A3/cs unknown
- 1999-03-04 ID IDW20001811A patent/ID25651A/id unknown
- 1999-03-04 KR KR10-2000-7010264A patent/KR100372981B1/ko not_active Expired - Fee Related
- 1999-03-04 ES ES99905122T patent/ES2224604T3/es not_active Expired - Lifetime
- 1999-03-04 EP EP99905122A patent/EP1064256B1/en not_active Expired - Lifetime
- 1999-03-04 CN CNB998040401A patent/CN1231461C/zh not_active Expired - Fee Related
- 1999-03-04 AU AU25409/99A patent/AU753422B2/en not_active Ceased
- 1999-03-04 WO PCT/IB1999/000376 patent/WO1999047490A1/en not_active Ceased
- 1999-03-04 EA EA200000842A patent/EA003946B1/ru not_active IP Right Cessation
- 1999-03-04 TR TR2000/02671T patent/TR200002671T2/xx unknown
- 1999-03-04 SK SK1353-2000A patent/SK13532000A3/sk unknown
- 1999-03-04 BR BR9908850-9A patent/BR9908850A/pt not_active Application Discontinuation
- 1999-03-04 CA CA002321639A patent/CA2321639C/en not_active Expired - Fee Related
- 1999-03-04 HU HU0101031A patent/HUP0101031A3/hu unknown
- 1999-03-10 AP APAP/P/1999/001482A patent/AP1116A/en active
- 1999-03-12 TW TW088103874A patent/TW509667B/zh not_active IP Right Cessation
- 1999-03-12 PE PE1999000198A patent/PE20000339A1/es not_active Application Discontinuation
- 1999-03-15 MY MYPI99000966A patent/MY121047A/en unknown
- 1999-03-15 AR ARP990101118A patent/AR017236A1/es unknown
- 1999-03-16 GT GT199900040A patent/GT199900040A/es unknown
- 1999-03-16 TN TNTNSN99039A patent/TNSN99039A1/fr unknown
- 1999-03-16 MA MA25498A patent/MA26614A1/fr unknown
- 1999-03-16 ZA ZA9902094A patent/ZA992094B/xx unknown
- 1999-03-16 DZ DZ990046A patent/DZ2745A1/xx active
- 1999-03-17 CO CO99016567A patent/CO5090835A1/es unknown
- 1999-04-03 UA UA2000095327A patent/UA53781C2/uk unknown
-
2000
- 2000-08-18 IS IS5592A patent/IS5592A/is unknown
- 2000-09-15 NO NO20004626A patent/NO20004626L/no not_active Application Discontinuation
- 2000-09-18 OA OA1200000258A patent/OA11488A/en unknown
- 2000-10-11 BG BG104837A patent/BG104837A/bg unknown
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