SG63698A1 - Novel pyrimido (1,2-a) indoles - Google Patents

Novel pyrimido (1,2-a) indoles

Info

Publication number: SG63698A1
Authority: SG; Singapore
Prior art keywords: indoles; novel pyrimido; pyrimido; novel
Prior art date: 1996-04-04

Application number

SG1997001026A

Other languages

English (en)

Inventor

Ulrich Muller

Peter Eckenberg

Rudi Grutzmann

Hilmar Bischoff

Dirk Denzer

Stefan Wohlfeil

Stefan Lohmer

Ulrich Nielsch

Peter Kolkhof

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-04

Filing date

1997-04-01

Publication date

1999-03-30

1997-04-01 Application filed by Bayer Ag filed Critical Bayer Ag

1999-03-30 Publication of SG63698A1 publication Critical patent/SG63698A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SG1997001026A 1996-04-04 1997-04-01 Novel pyrimido (1,2-a) indoles SG63698A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19613550A DE19613550A1 (de)	1996-04-04	1996-04-04	Neue Pyrimido[1,2-a]indole

Publications (1)

Publication Number	Publication Date
SG63698A1 true SG63698A1 (en)	1999-03-30

Family

ID=7790502

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG1997001026A SG63698A1 (en)	1996-04-04	1997-04-01	Novel pyrimido (1,2-a) indoles

Country Status (33)

Country	Link
US (1)	US6114341A (es)
EP (1)	EP0799828A3 (es)
JP (1)	JPH1059972A (es)
KR (1)	KR970070008A (es)
CN (2)	CN1067393C (es)
AR (1)	AR006497A1 (es)
AU (1)	AU725786B2 (es)
BG (1)	BG62934B1 (es)
BR (1)	BR9701675A (es)
CA (1)	CA2201434A1 (es)
CO (1)	CO4520306A1 (es)
CZ (1)	CZ102297A3 (es)
DE (1)	DE19613550A1 (es)
DZ (1)	DZ2201A1 (es)
EE (1)	EE9700078A (es)
HN (1)	HN1997000045A (es)
HR (1)	HRP970154A2 (es)
HU (1)	HUP9700708A3 (es)
ID (1)	ID16520A (es)
IL (3)	IL131645A (es)
MA (1)	MA24131A1 (es)
MY (1)	MY126362A (es)
NO (1)	NO309092B1 (es)
NZ (1)	NZ314497A (es)
PE (1)	PE42398A1 (es)
PL (1)	PL319249A1 (es)
SG (1)	SG63698A1 (es)
SK (1)	SK42797A3 (es)
SV (1)	SV1997000025A (es)
TN (1)	TNSN97061A1 (es)
TR (1)	TR199700261A2 (es)
YU (1)	YU12397A (es)
ZA (1)	ZA972829B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19826469A1 (de) *	1998-06-13	2000-05-25	Bayer Ag	Verfahren zur Herstellung von 2,4-Dimethylcarbolin und 2,4-Dimethylpyrimido[1,2-a]indol
WO2001074817A1 (en) *	2000-03-30	2001-10-11	Yamanouchi Pharmaceutical Co., Ltd.	Hydrazide derivatives
DE10030375A1 (de) *	2000-06-21	2002-01-03	Bayer Ag	Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
JP4254093B2 (ja) *	2001-10-17	2009-04-15	宇部興産株式会社	５−ハロゲノインドールの製法
DE10349175A1 (de) *	2003-10-22	2005-05-19	Bayer Healthcare Ag	Mittel zur Gewichtsreduktion
CA2910191C (en)	2004-03-05	2022-03-08	The Trustees Of The Univeristy Of Pennsylvania	The use of mtp inhibitors for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side effects
AU2005230397B2 (en) *	2004-04-09	2010-04-08	Elanco Animal Health Ireland Limited	Intermittent dosing regimen for the treatment of overweight with MTP-inhibitors
JP5102201B2 (ja)	2005-05-12	2012-12-19	シー・アール・バード・インコーポレーテッド	取り外し可能な塞栓血餅フィルタ
JP2008542255A (ja) *	2005-05-27	2008-11-27	ファイザー・プロダクツ・インク	肥満症の治療または体重減量の維持のためのカンナビノイド−１受容体アンタゴニストおよびミクロソームトリグリセリド輸送タンパク質阻害物質の併用
US8062327B2 (en)	2005-08-09	2011-11-22	C. R. Bard, Inc.	Embolus blood clot filter and delivery system
CA2626461A1 (en) *	2005-10-18	2007-04-26	Aegerion Pharmaceuticals	Compositions for lowering serum cholesterol and/or triglycerides
WO2007133366A2 (en)	2006-05-02	2007-11-22	C. R. Bard, Inc.	Vena cava filter formed from a sheet
WO2008079398A1 (en) *	2006-12-21	2008-07-03	Aegerion Pharmaceuticals, Inc.	Methods for treating obesity with a combination comprising a mtp inhibitor and a cholesterol absorption inhibitor
AU2021316011A1 (en)	2020-07-29	2023-02-09	Amryt Pharmaceuticals Inc.	Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA718536B (en) *	1971-01-11	1972-09-27	Wyeth John & Brother Ltd	Heterocyclic compounds
DE2200584A1 (de) *	1971-01-11	1972-07-27	Wyeth John & Brother Ltd	Heterocyclische Verbindungen,Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen Zubereitungen
GB8614246D0 (en) *	1986-06-11	1986-07-16	Wyeth John & Brother Ltd	Substituted pyrimidoindoles
DE4112533A1 (de) *	1991-04-17	1992-10-22	Bayer Ag	Verfahren zur herstellung von enantiomerenreinen substituierten (chinolin-2-yl-methoxy)phenyl-essigsaeuren
DE4200954A1 (de) *	1991-04-26	1992-10-29	Bayer Ag	Heterocyclisch substituierte phenylessigsaeurederivate
DE4309968A1 (de) *	1993-03-26	1994-09-29	Bayer Ag	Phenylglycinamide von heterocyclisch substituierten Phenylessigsäurederivaten
DE4208052A1 (de) *	1992-03-13	1993-09-16	Bayer Ag	Imidazolyl substituierte phenylessigsaeureamide
US5576342A (en) *	1992-03-13	1996-11-19	Bayer Aktiengesellschaft	Phenylglycinamides of heterocyclically substitued phenylacetic acid derivatives
DE4208051A1 (de) *	1992-03-13	1993-09-16	Bayer Ag	Substituierte phenylessigsaeureamide
US5705498A (en) *	1992-11-05	1998-01-06	Smithkline Beecham Plc.	Piperidine derivatives as 5-HT4 receptor antagonists
DE4302956A1 (de) *	1993-02-03	1994-08-04	Bayer Ag	Substituierte Imidazo(4,5-b)pyridine und Benzimidazole

1996
- 1996-04-04 DE DE19613550A patent/DE19613550A1/de not_active Withdrawn
1997
- 1997-03-17 HR HR19613550.8A patent/HRP970154A2/xx not_active Application Discontinuation
- 1997-03-24 EP EP97104940A patent/EP0799828A3/de not_active Ceased
- 1997-03-27 NZ NZ314497A patent/NZ314497A/xx unknown
- 1997-03-27 AU AU16603/97A patent/AU725786B2/en not_active Ceased
- 1997-03-31 US US08/829,015 patent/US6114341A/en not_active Expired - Fee Related
- 1997-04-01 SG SG1997001026A patent/SG63698A1/en unknown
- 1997-04-01 MA MA24544A patent/MA24131A1/fr unknown
- 1997-04-01 CA CA002201434A patent/CA2201434A1/en not_active Abandoned
- 1997-04-01 YU YU12397A patent/YU12397A/sr unknown
- 1997-04-02 DZ DZ970048A patent/DZ2201A1/fr active
- 1997-04-02 BG BG101379A patent/BG62934B1/bg unknown
- 1997-04-02 IL IL13164597A patent/IL131645A/xx not_active IP Right Cessation
- 1997-04-02 TR TR97/00261A patent/TR199700261A2/xx unknown
- 1997-04-02 ID IDP971112A patent/ID16520A/id unknown
- 1997-04-02 PL PL97319249A patent/PL319249A1/xx unknown
- 1997-04-02 IL IL12059097A patent/IL120590A/xx not_active IP Right Cessation
- 1997-04-02 JP JP9097893A patent/JPH1059972A/ja not_active Withdrawn
- 1997-04-02 TN TNTNSN97061A patent/TNSN97061A1/fr unknown
- 1997-04-03 ZA ZA9702829A patent/ZA972829B/xx unknown
- 1997-04-03 EE EE9700078A patent/EE9700078A/xx unknown
- 1997-04-03 AR ARP970101336A patent/AR006497A1/es unknown
- 1997-04-03 SK SK427-97A patent/SK42797A3/sk unknown
- 1997-04-03 NO NO971512A patent/NO309092B1/no not_active IP Right Cessation
- 1997-04-03 MY MYPI97001435A patent/MY126362A/en unknown
- 1997-04-03 KR KR1019970012342A patent/KR970070008A/ko not_active Withdrawn
- 1997-04-03 PE PE1997000260A patent/PE42398A1/es not_active Application Discontinuation
- 1997-04-03 CZ CZ971022A patent/CZ102297A3/cs unknown
- 1997-04-03 CO CO97016906A patent/CO4520306A1/es unknown
- 1997-04-04 CN CN97110275A patent/CN1067393C/zh not_active Expired - Fee Related
- 1997-04-04 SV SV1997000025A patent/SV1997000025A/es unknown
- 1997-04-04 BR BR9701675A patent/BR9701675A/pt active Search and Examination
- 1997-04-04 HU HU9700708A patent/HUP9700708A3/hu unknown
- 1997-04-04 HN HN1997000045A patent/HN1997000045A/es unknown
1999
- 1999-08-30 IL IL13164599A patent/IL131645A0/xx unknown
2000
- 2000-09-12 CN CN00127092A patent/CN1312246A/zh active Pending

Also Published As

Publication number	Publication date
CA2201434A1 (en)	1997-10-04
SK42797A3 (en)	1997-11-05
SV1997000025A (es)	1997-10-23
CN1067393C (zh)	2001-06-20
ZA972829B (en)	1997-10-31
DZ2201A1 (fr)	2002-12-03
CO4520306A1 (es)	1997-10-15
CZ102297A3 (en)	1997-10-15
BG101379A (en)	1997-11-28
HUP9700708A3 (en)	2000-01-28
HRP970154A2 (en)	1998-04-30
PL319249A1 (en)	1997-10-13
AR006497A1 (es)	1999-08-25
ID16520A (id)	1997-10-09
IL120590A0 (en)	1997-08-14
EP0799828A3 (de)	1998-04-08
HN1997000045A (es)	1997-06-26
CN1312246A (zh)	2001-09-12
MX9702445A (es)	1997-10-31
YU12397A (en)	1999-11-22
MY126362A (en)	2006-09-29
AU1660397A (en)	1997-10-09
AU725786B2 (en)	2000-10-19
TR199700261A2 (xx)	1997-10-21
NZ314497A (en)	1999-10-28
JPH1059972A (ja)	1998-03-03
NO309092B1 (no)	2000-12-11
IL131645A0 (en)	2001-01-28
IL131645A (en)	2000-12-06
PE42398A1 (es)	1998-10-12
US6114341A (en)	2000-09-05
MA24131A1 (fr)	1997-10-01
HU9700708D0 (en)	1997-05-28
KR970070008A (ko)	1997-11-07
HUP9700708A2 (hu)	1998-10-28
IL120590A (en)	2000-02-17
NO971512L (no)	1997-10-06
BR9701675A (pt)	1998-11-03
CN1176965A (zh)	1998-03-25
EE9700078A (et)	1997-10-15
BG62934B1 (bg)	2000-11-30
DE19613550A1 (de)	1997-10-09
TNSN97061A1 (fr)	2005-03-15
NO971512D0 (no)	1997-04-03
EP0799828A2 (de)	1997-10-08

Publication	Publication Date	Title
AP9701077A0 (en)	1997-10-31	Substituted 6,5-hetero bicyclic derivatives
AP9701076A0 (en)	1997-10-31	Substituted 6,6-hetero bicyclic derivatives
GB9817351D0 (en)	1998-10-07	Multi-purpose dolly-truck
ZA979593B (en)	1998-04-28	Naphthyridine derivatives.
SI0891978T1 (en)	2002-06-30	5H-Thiazolo (3,2-a) pyrimidine derivatives
SG63698A1 (en)	1999-03-30	Novel pyrimido (1,2-a) indoles
GB9603146D0 (en)	1996-04-17	Hydrogels
NZ320537A (en)	1999-03-29	2,7-substituted octahydro-pyrrolo(1,2-a)pyrazine derivatives
GB2311779B (en)	1999-07-14	2,3 benzodiazepine derivatives
AU5172296A (en)	1996-09-18	Pyrimido{4,5-b}indoles
HUP0003692A3 (en)	2002-10-28	Pyrimido[4,5-b]indolyl-alkanecarboxamide derivatives
GB9602095D0 (en)	1996-04-03	Phthalocyanines
GB2316072B (en)	2000-05-10	Pyrrolo[3,2-c]quinoline derivatives
SG64421A1 (en)	1999-04-27	Imidazothiazoles
HU9700545D0 (en)	1997-04-28	(2,3-dihydro-5-benzofuranyl)-acetonitril
AU7073296A (en)	1997-11-19	5,6,7,8-tetrahydropyrido{2,3-d}pyrimidines
PL105610U1 (en)	1998-05-25	Multi-purpose minitractor
ZA978806B (en)	1998-07-23	Indole-2,3-dione-3-oxime derivatives
AU7322196A (en)	1997-08-11	Pyrido (3,2,1-ij)-1,3,4-benzoxadiazine
KR200157515Y1 (en)	1999-09-15	Multi-purpose keeping structure
ZA979840B (en)	1998-05-26	Bicyclic amine derivatives.
ZA974089B (en)	1997-11-13	Bicyclic amines.
GB9624020D0 (en)	1997-01-08	Multi-purpose support
AU6344396A (en)	1998-01-21	5,6,7,8-tetrahydropyrimido{4,5-b}azepine derivatives
AU6816296A (en)	1998-04-23	Multi-purpose dolly-truck