SG131944A1 - N3-substituted imidazopyridine-derivatives as c-kit inhibitors - Google Patents
N3-substituted imidazopyridine-derivatives as c-kit inhibitorsInfo
- Publication number
- SG131944A1 SG131944A1 SG200702982-0A SG2007029820A SG131944A1 SG 131944 A1 SG131944 A1 SG 131944A1 SG 2007029820 A SG2007029820 A SG 2007029820A SG 131944 A1 SG131944 A1 SG 131944A1
- Authority
- SG
- Singapore
- Prior art keywords
- derivatives
- kit inhibitors
- substituted imidazopyridine
- imidazopyridine
- substituted
- Prior art date
Links
- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 title 1
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49677603P | 2003-08-21 | 2003-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG131944A1 true SG131944A1 (en) | 2007-05-28 |
Family
ID=34272515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200702982-0A SG131944A1 (en) | 2003-08-21 | 2004-08-16 | N3-substituted imidazopyridine-derivatives as c-kit inhibitors |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1658289B1 (is) |
| JP (1) | JP2007502822A (is) |
| KR (1) | KR20060119871A (is) |
| CN (1) | CN1839132A (is) |
| AP (1) | AP2006003552A0 (is) |
| AR (1) | AR045388A1 (is) |
| AT (1) | ATE425977T1 (is) |
| AU (1) | AU2004268950A1 (is) |
| BR (1) | BRPI0413740A (is) |
| CA (1) | CA2536174A1 (is) |
| DE (1) | DE602004020073D1 (is) |
| IL (1) | IL173615A0 (is) |
| IS (1) | IS8318A (is) |
| MX (1) | MXPA06002019A (is) |
| MY (1) | MY138737A (is) |
| NO (1) | NO20060670L (is) |
| RU (1) | RU2006108799A (is) |
| SG (1) | SG131944A1 (is) |
| TW (1) | TW200519111A (is) |
| WO (1) | WO2005021544A2 (is) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0625827D0 (en) * | 2006-12-22 | 2007-02-07 | Astex Therapeutics Ltd | New compounds |
| JP5442448B2 (ja) | 2006-12-22 | 2014-03-12 | アステックス、セラピューティックス、リミテッド | Ｆｇｆｒインヒビターとしての二環式ヘテロ環式化合物 |
| PL2121687T3 (pl) | 2006-12-22 | 2016-03-31 | Astex Therapeutics Ltd | Pochodne amin tricyklicznych jako inhibitory białkowej kinazy tyrozynowej |
| GB0720041D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New Compounds |
| GB0720038D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New compounds |
| CN105461589A (zh) | 2008-05-05 | 2016-04-06 | 赛诺菲-安万特 | 酰基氨基取代的稠合环戊烷羧酸衍生物及它们作为药物的用途 |
| GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
| PL2308877T3 (pl) * | 2008-08-05 | 2014-07-31 | Daiichi Sankyo Co Ltd | Pochodne imidazopirydyn-2-onu |
| WO2010045276A2 (en) * | 2008-10-16 | 2010-04-22 | Cara Therapeutics, Inc. | Azabenzimidazolones |
| WO2010099139A2 (en) | 2009-02-25 | 2010-09-02 | Osi Pharmaceuticals, Inc. | Combination anti-cancer therapy |
| US8465912B2 (en) | 2009-02-27 | 2013-06-18 | OSI Pharmaceuticals, LLC | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
| WO2010099138A2 (en) | 2009-02-27 | 2010-09-02 | Osi Pharmaceuticals, Inc. | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
| US8642834B2 (en) | 2009-02-27 | 2014-02-04 | OSI Pharmaceuticals, LLC | Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation |
| GB0906470D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| GB0906472D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| AR079022A1 (es) | 2009-11-02 | 2011-12-21 | Sanofi Aventis | Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion |
| AU2010339533B2 (en) * | 2009-12-30 | 2015-05-07 | Arqule, Inc. | Substituted imidazopyridinyl-aminopyridine compounds |
| WO2012149014A1 (en) | 2011-04-25 | 2012-11-01 | OSI Pharmaceuticals, LLC | Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment |
| BR112013033182A2 (pt) * | 2011-06-24 | 2016-09-06 | Arqule Inc | compostos imidazopiridinil-aminopiridina substituída |
| WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| SMT201800230T1 (it) | 2012-12-21 | 2018-07-17 | Plexxikon Inc | Composti e metodi per la modulazione della chinasi e loro indicazioni |
| JP6578298B2 (ja) * | 2014-03-24 | 2019-09-18 | アークル インコーポレイテッド | ３−（３−（４−（１−アミノシクロブチル）フェニル）−５−フェニル−３ｈ−イミダゾ［４，５−ｂ］ピリジン−２−イル）ピリジン−２−アミンを調製する方法 |
| EP3594205A1 (en) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-aryl derivatives for treating a rna virus infection |
| EP3594206A1 (en) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-quinoline derivatives for treating a rna virus infection |
| EP3942045A1 (en) | 2019-03-21 | 2022-01-26 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| JP2023500906A (ja) | 2019-11-08 | 2023-01-11 | インサーム（インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル） | キナーゼ阻害剤に対する獲得抵抗性を有するがんの処置方法 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| JP2023524465A (ja) | 2020-04-29 | 2023-06-12 | プレキシコン インコーポレイティド | 複素環式化合物の合成 |
| TW202428265A (zh) * | 2022-11-30 | 2024-07-16 | 日商亞力維克希斯股份有限公司 | Kit抑制劑、化合物、醫藥組合物、及其使用方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4129603A1 (de) * | 1991-09-06 | 1993-03-11 | Thomae Gmbh Dr K | Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| TW251284B (is) * | 1992-11-02 | 1995-07-11 | Pfizer | |
| AU6966696A (en) | 1995-10-05 | 1997-04-28 | Warner-Lambert Company | Method for treating and preventing inflammation and atherosclerosis |
| US5990146A (en) | 1997-08-20 | 1999-11-23 | Warner-Lambert Company | Benzimidazoles for inhibiting protein tyrosine kinase mediated cellular proliferation |
| US6326379B1 (en) | 1998-09-16 | 2001-12-04 | Bristol-Myers Squibb Co. | Fused pyridine inhibitors of cGMP phosphodiesterase |
| US6348032B1 (en) | 1998-11-23 | 2002-02-19 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with benzimidazole derivatives |
| AU6762400A (en) | 1999-08-12 | 2001-03-13 | Cor Therapeutics, Inc. | Inhibitors of factor xa |
| EP1214330A1 (en) | 1999-09-21 | 2002-06-19 | LION Bioscience AG | Benzimidazole derivatives and combinatorial libraries thereof |
| AU2001236605A1 (en) | 2000-02-01 | 2001-08-14 | Cor Therapeutics, Inc. | Indole and benzimidazole inhibitors of factor xa |
| AU2002334355A1 (en) * | 2001-09-06 | 2003-03-18 | Prochon Biotech Ltd. | Protein tyrosine kinase inhibitors |
-
2004
- 2004-08-16 DE DE602004020073T patent/DE602004020073D1/de not_active Expired - Lifetime
- 2004-08-16 JP JP2006523956A patent/JP2007502822A/ja active Pending
- 2004-08-16 SG SG200702982-0A patent/SG131944A1/en unknown
- 2004-08-16 AT AT04781205T patent/ATE425977T1/de not_active IP Right Cessation
- 2004-08-16 CA CA002536174A patent/CA2536174A1/en not_active Abandoned
- 2004-08-16 CN CNA2004800240419A patent/CN1839132A/zh active Pending
- 2004-08-16 RU RU2006108799/04A patent/RU2006108799A/ru not_active Application Discontinuation
- 2004-08-16 BR BRPI0413740-0A patent/BRPI0413740A/pt not_active IP Right Cessation
- 2004-08-16 KR KR1020067003586A patent/KR20060119871A/ko not_active Withdrawn
- 2004-08-16 AU AU2004268950A patent/AU2004268950A1/en not_active Abandoned
- 2004-08-16 EP EP04781205A patent/EP1658289B1/en not_active Expired - Lifetime
- 2004-08-16 MX MXPA06002019A patent/MXPA06002019A/es unknown
- 2004-08-16 WO PCT/US2004/026483 patent/WO2005021544A2/en not_active Ceased
- 2004-08-16 AP AP2006003552A patent/AP2006003552A0/xx unknown
- 2004-08-20 AR ARP040103009A patent/AR045388A1/es not_active Application Discontinuation
- 2004-08-20 TW TW093125235A patent/TW200519111A/zh unknown
- 2004-08-20 MY MYPI20043423A patent/MY138737A/en unknown
-
2006
- 2006-02-08 IL IL173615A patent/IL173615A0/en unknown
- 2006-02-10 NO NO20060670A patent/NO20060670L/no not_active Application Discontinuation
- 2006-02-21 IS IS8318A patent/IS8318A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL173615A0 (en) | 2006-07-05 |
| AU2004268950A1 (en) | 2005-03-10 |
| WO2005021544A3 (en) | 2005-06-16 |
| AP2006003552A0 (en) | 2006-04-30 |
| DE602004020073D1 (de) | 2009-04-30 |
| AR045388A1 (es) | 2005-10-26 |
| NO20060670L (no) | 2006-05-12 |
| WO2005021544A2 (en) | 2005-03-10 |
| RU2006108799A (ru) | 2006-07-27 |
| ATE425977T1 (de) | 2009-04-15 |
| MXPA06002019A (es) | 2006-05-31 |
| BRPI0413740A (pt) | 2006-10-24 |
| CN1839132A (zh) | 2006-09-27 |
| EP1658289A2 (en) | 2006-05-24 |
| TW200519111A (en) | 2005-06-16 |
| KR20060119871A (ko) | 2006-11-24 |
| IS8318A (is) | 2006-02-21 |
| EP1658289B1 (en) | 2009-03-18 |
| CA2536174A1 (en) | 2005-03-10 |
| JP2007502822A (ja) | 2007-02-15 |
| MY138737A (en) | 2009-07-31 |
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