SE8601907D0 - Imidazoquinoline antithrombogenic cardiotonic agents - Google Patents

Imidazoquinoline antithrombogenic cardiotonic agents

Info

Publication number: SE8601907D0
Authority: SE; Sweden
Prior art keywords: imidazoquinoline; antithrombogenic; cardiotonic agents; lower alkyl; halogen
Prior art date: 1985-04-25

Application number

SE8601907A

Other languages

English (en)

Other versions

SE461468B (sv

SE8601907L (sv

Inventor

N A Meanwell

J J Wright

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-25

Filing date

1986-04-24

Publication date

1986-04-24

1986-04-24 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1986-04-24 Publication of SE8601907D0 publication Critical patent/SE8601907D0/sv

1986-10-26 Publication of SE8601907L publication Critical patent/SE8601907L/sv

1990-02-19 Publication of SE461468B publication Critical patent/SE461468B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SE8601907A 1985-04-25 1986-04-24 Imidazo 4,5-b kinolin-2-on-derivat, foerfarande foer framstaellning av detta, mellanprodukter och en farmaceutisk beredning SE461468B (sv)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US72686985A	1985-04-25	1985-04-25
US06/832,212 US4668686A (en)	1985-04-25	1986-02-26	Imidazoquinoline antithrombrogenic cardiotonic agents

Publications (3)

Publication Number	Publication Date
SE8601907D0 true SE8601907D0 (sv)	1986-04-24
SE8601907L SE8601907L (sv)	1986-10-26
SE461468B SE461468B (sv)	1990-02-19

Family

ID=27111398

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8601907A SE461468B (sv)	1985-04-25	1986-04-24	Imidazo 4,5-b kinolin-2-on-derivat, foerfarande foer framstaellning av detta, mellanprodukter och en farmaceutisk beredning

Country Status (32)

Country	Link
US (1)	US4668686A (sv)
KR (1)	KR940000828B1 (sv)
CN (1)	CN1016175B (sv)
AT (1)	AT390257B (sv)
AU (1)	AU592983B2 (sv)
BE (1)	BE904671A (sv)
CA (1)	CA1298836C (sv)
CH (1)	CH675722A5 (sv)
CY (1)	CY1641A (sv)
DE (1)	DE3614132A1 (sv)
DK (3)	DK164868C (sv)
EG (1)	EG18104A (sv)
ES (3)	ES8708229A1 (sv)
FI (1)	FI83316C (sv)
FR (1)	FR2581065B1 (sv)
GB (1)	GB2174987B (sv)
GR (1)	GR861086B (sv)
HK (1)	HK64492A (sv)
HU (1)	HU195813B (sv)
IL (1)	IL78581A0 (sv)
IT (1)	IT1215651B (sv)
LU (1)	LU86406A1 (sv)
MY (1)	MY102086A (sv)
NL (1)	NL8601053A (sv)
NO (1)	NO163406C (sv)
NZ (1)	NZ215885A (sv)
OA (1)	OA08242A (sv)
PT (1)	PT82460B (sv)
SE (1)	SE461468B (sv)
SG (1)	SG29092G (sv)
SU (3)	SU1450746A3 (sv)
YU (1)	YU46054B (sv)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4775674A (en) *	1986-05-23	1988-10-04	Bristol-Myers Company	Imidazoquinolinylether derivatives useful as phosphodiesterase and blood aggregation inhibitors
US4701459A (en) *	1986-07-08	1987-10-20	Bristol-Myers Company	7-amino-1,3-dihydro-2H-imidazo[4,5-b]quinolin 2-ones and method for inhibiting phosphodiesterase and blood platelet aggregation
US4803210A (en) *	1987-05-29	1989-02-07	Merrell Dow Pharmaceuticals Inc.	Cardiotonic tricyclic oxazolones
US4743607A (en) *	1987-05-29	1988-05-10	Merrell Dow Pharmaceuticals Inc.	Cardiotonic tricyclic imidazolones
US4943573A (en) *	1989-11-01	1990-07-24	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyloxyalkanoic acid amides with enhanced water solubility
DE4035854C2 (de) *	1990-11-10	1996-10-02	Daimler Benz Ag	Vorrichtung zum Fangen und Ableiten des von einem Fahrzeugrad hochgeschleuderten Spritzwassers
PH31245A (en) *	1991-10-30	1998-06-18	Janssen Pharmaceutica Nv	1,3-Dihydro-2H-imidazoÄ4,5-BÜ-quinolin-2-one derivatives.
US5348960A (en) *	1992-04-03	1994-09-20	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl tetrazolyl piperidine derivatives
US5196428A (en) *	1992-04-03	1993-03-23	Bristol-Myers Squibb Company	Imidazo[4,5-b]qinolinyl oxy alkyl ureas
US5552267A (en) *	1992-04-03	1996-09-03	The Trustees Of Columbia University In The City Of New York	Solution for prolonged organ preservation
US5158958A (en) *	1992-04-03	1992-10-27	Bristol-Myers Squibb Company	Imidazo[4,5-b]quinolinyl oxy alkyl sulfonyl piperidine derivatives
US5208237A (en) *	1992-04-03	1993-05-04	Bristol-Meyers Squibb Company	7-oxypropylsulfonamido-imidazo[4,5-b]quinolin-2-ones
TW593317B (en) *	1993-06-21	2004-06-21	Janssen Pharmaceutica Nv	Positive cardiac inotropic and lusitropic pyrroloquinolinone derivatives
CA2166721C (en) *	1993-07-06	1999-07-27	Allen Jacob Duplantier	Bicyclic tetrahydro pyrazolopyridines
TW574214B (en) *	1994-06-08	2004-02-01	Pfizer	Corticotropin releasing factor antagonists
US6664264B2 (en) *	2000-12-08	2003-12-16	3M Innovative Properties Company	Thioether substituted imidazoquinolines
TW200510412A (en)	2003-08-12	2005-03-16	3M Innovative Properties Co	Oxime substituted imidazo-containing compounds
AR045529A1 (es)	2003-08-27	2005-11-02	3M Innovative Properties Co	Imidazoquinolinas sustituidas con grupos ariloxi o arilalquilenoxi
CA2537763A1 (en)	2003-09-05	2005-03-17	3M Innovative Properties Company	Treatment for cd5+ b cell lymphoma
WO2005032484A2 (en)	2003-10-03	2005-04-14	3M Innovative Properties Company	Alkoxy substituted imidazoquinolines
US7544697B2 (en)	2003-10-03	2009-06-09	Coley Pharmaceutical Group, Inc.	Pyrazolopyridines and analogs thereof
JP2007511527A (ja)	2003-11-14	2007-05-10	スリーエムイノベイティブプロパティズカンパニー	オキシム置換イミダゾ環化合物
EP1682544A4 (en) *	2003-11-14	2009-05-06	3M Innovative Properties Co	HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS
AU2004293078B2 (en)	2003-11-25	2012-01-19	3M Innovative Properties Company	Substituted imidazo ring systems and methods
US8802853B2 (en)	2003-12-29	2014-08-12	3M Innovative Properties Company	Arylalkenyl and arylalkynyl substituted imidazoquinolines
EP1699788A2 (en)	2003-12-30	2006-09-13	3M Innovative Properties Company	Imidazoquinolinyl, imidazopyridinyl and imidazonaphthyridinyl sulfonamides
EP1730143A2 (en)	2004-03-24	2006-12-13	3M Innovative Properties Company	Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en)	2004-06-15	2011-09-13	3M Innovative Properties Company	Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US7897609B2 (en)	2004-06-18	2011-03-01	3M Innovative Properties Company	Aryl substituted imidazonaphthyridines
WO2006065280A2 (en)	2004-06-18	2006-06-22	3M Innovative Properties Company	Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
US8026366B2 (en)	2004-06-18	2011-09-27	3M Innovative Properties Company	Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
MX2007003078A (es) *	2004-09-14	2007-05-16	Novartis Vaccines & Diagnostic	Compuestos de imidazoquinolina.
WO2006083440A2 (en)	2004-12-30	2006-08-10	3M Innovative Properties Company	Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
AU2005322898B2 (en)	2004-12-30	2011-11-24	3M Innovative Properties Company	Chiral fused (1,2)imidazo(4,5-c) ring compounds
WO2006084251A2 (en)	2005-02-04	2006-08-10	Coley Pharmaceutical Group, Inc.	Aqueous gel formulations containing immune reponse modifiers
US7968563B2 (en)	2005-02-11	2011-06-28	3M Innovative Properties Company	Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
WO2006107853A2 (en)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	Pyrazolopyridine-1,4-diamines and analogs thereof
CA2602590A1 (en)	2005-04-01	2006-10-12	Coley Pharmaceutical Group, Inc.	1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US7906506B2 (en)	2006-07-12	2011-03-15	3M Innovative Properties Company	Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
US8227603B2 (en)	2006-08-01	2012-07-24	Cytokinetics, Inc.	Modulating skeletal muscle
US8299248B2 (en)	2006-08-02	2012-10-30	Cytokinetics, Incorporated	Certain 1H-imidazo[4,5-b]pyrazin-2(3H)-ones and 1H-imidazo[4,5-b]pyrazin-2-ols and methods for their use
HUE026571T2 (hu)	2006-08-02	2016-06-28	Cytokinetics Inc	Adott kémiai anyagok, készítmények és imidazopiridineket magukba foglaló eljárások
WO2008121333A1 (en) *	2007-03-30	2008-10-09	Cytokinetics, Incorporated	Certain chemical entities, compositions and methods
CN109316480A (zh)	2011-07-13	2019-02-12	赛特凯恩蒂克公司	组合als疗法
CN120265631A (zh) *	2023-01-13	2025-07-04	上海超阳药业有限公司	喹啉酮化合物和萘啶酮化合物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3932407A (en) *	1973-11-19	1976-01-13	Bristol-Myers Company	Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones

1986
- 1986-02-26 US US06/832,212 patent/US4668686A/en not_active Expired - Fee Related
- 1986-03-26 CA CA000505136A patent/CA1298836C/en not_active Expired - Fee Related
- 1986-04-18 NZ NZ215885A patent/NZ215885A/xx unknown
- 1986-04-21 AU AU56413/86A patent/AU592983B2/en not_active Ceased
- 1986-04-22 FI FI861684A patent/FI83316C/sv not_active IP Right Cessation
- 1986-04-22 IL IL78581A patent/IL78581A0/xx not_active IP Right Cessation
- 1986-04-23 CN CN86102747A patent/CN1016175B/zh not_active Expired
- 1986-04-23 EG EG237/86A patent/EG18104A/xx active
- 1986-04-24 LU LU86406A patent/LU86406A1/fr unknown
- 1986-04-24 CH CH1679/86A patent/CH675722A5/de not_active IP Right Cessation
- 1986-04-24 BE BE0/216585A patent/BE904671A/fr not_active IP Right Cessation
- 1986-04-24 SE SE8601907A patent/SE461468B/sv not_active IP Right Cessation
- 1986-04-24 DK DK190986A patent/DK164868C/da not_active IP Right Cessation
- 1986-04-24 IT IT8620206A patent/IT1215651B/it active
- 1986-04-24 PT PT82460A patent/PT82460B/pt not_active IP Right Cessation
- 1986-04-24 ES ES554336A patent/ES8708229A1/es not_active Expired
- 1986-04-24 FR FR868605966A patent/FR2581065B1/fr not_active Expired - Fee Related
- 1986-04-24 NL NL8601053A patent/NL8601053A/xx not_active Application Discontinuation
- 1986-04-24 SU SU864027355A patent/SU1450746A3/ru active
- 1986-04-24 GB GB8610037A patent/GB2174987B/en not_active Expired
- 1986-04-24 GR GR861086A patent/GR861086B/el unknown
- 1986-04-24 NO NO861617A patent/NO163406C/no unknown
- 1986-04-25 KR KR1019860003204A patent/KR940000828B1/ko not_active Expired - Lifetime
- 1986-04-25 DE DE19863614132 patent/DE3614132A1/de not_active Ceased
- 1986-04-25 AT AT0112186A patent/AT390257B/de not_active IP Right Cessation
- 1986-04-25 HU HU861723A patent/HU195813B/hu not_active IP Right Cessation
- 1986-04-25 OA OA58845A patent/OA08242A/xx unknown
1987
- 1987-02-27 SU SU874202071A patent/SU1470192A3/ru active
- 1987-05-14 ES ES557552A patent/ES8802521A1/es not_active Expired
- 1987-05-14 ES ES557551A patent/ES8801829A1/es not_active Expired
- 1987-06-23 YU YU116787A patent/YU46054B/sh unknown
- 1987-09-25 SU SU874203391A patent/SU1560056A3/ru active
- 1987-09-29 MY MYPI87002266A patent/MY102086A/en unknown
1991
- 1991-04-30 DK DK080291A patent/DK165248C/da not_active IP Right Cessation
- 1991-05-01 DK DK081091A patent/DK165249C/da not_active IP Right Cessation
1992
- 1992-03-10 SG SG290/92A patent/SG29092G/en unknown
- 1992-08-27 HK HK644/92A patent/HK64492A/xx unknown
- 1992-11-06 CY CY1641A patent/CY1641A/en unknown

Also Published As

Publication number	Publication date
NO163406C (no)	1990-05-23
DK165249B (da)	1992-10-26
YU116787A (en)	1988-04-30
OA08242A (en)	1987-10-30
NL8601053A (nl)	1986-11-17
DK81091D0 (da)	1991-05-01
GB2174987B (en)	1989-08-02
PT82460A (en)	1986-05-01
DK165248B (da)	1992-10-26
KR860008177A (ko)	1986-11-12
ES8802521A1 (es)	1988-07-16
IT8620206A0 (it)	1986-04-24
US4668686A (en)	1987-05-26
DK190986A (da)	1986-10-26
DK80291A (da)	1991-04-30
SU1470192A3 (ru)	1989-03-30
HUT42089A (en)	1987-06-29
AU5641386A (en)	1986-10-30
FR2581065A1 (fr)	1986-10-31
SE461468B (sv)	1990-02-19
AT390257B (de)	1990-04-10
DK190986D0 (da)	1986-04-24
SU1560056A3 (ru)	1990-04-23
SE8601907L (sv)	1986-10-26
IL78581A0 (en)	1986-08-31
CN86102747A (zh)	1987-02-04
PT82460B (pt)	1988-11-30
DK164868C (da)	1993-01-11
ES554336A0 (es)	1987-10-01
GR861086B (en)	1986-09-01
GB2174987A (en)	1986-11-19
CN1016175B (zh)	1992-04-08
DK165248C (da)	1993-03-22
DK81091A (da)	1991-05-01
DE3614132A1 (de)	1986-11-27
GB8610037D0 (en)	1986-05-29
IT1215651B (it)	1990-02-22
EG18104A (en)	1992-09-30
MY102086A (en)	1992-03-31
CA1298836C (en)	1992-04-14
SU1450746A3 (ru)	1989-01-07
BE904671A (fr)	1986-10-24
FI83316B (fi)	1991-03-15
CY1641A (en)	1992-11-06
DK80291D0 (da)	1991-04-30
NO861617L (no)	1986-10-27
AU592983B2 (en)	1990-02-01
LU86406A1 (fr)	1986-11-05
ES8708229A1 (es)	1987-10-01
CH675722A5 (sv)	1990-10-31
ES557552A0 (es)	1988-07-16
ES8801829A1 (es)	1988-02-16
KR940000828B1 (ko)	1994-02-02
NO163406B (no)	1990-02-12
SG29092G (en)	1992-05-15
HK64492A (en)	1992-09-04
ES557551A0 (es)	1988-02-16
YU46054B (sh)	1992-12-21
NZ215885A (en)	1989-04-26
DK165249C (da)	1993-03-22
FI83316C (sv)	1991-06-25
FI861684L (fi)	1986-10-26
ATA112186A (de)	1989-09-15
DK164868B (da)	1992-08-31
FR2581065B1 (fr)	1990-02-02
FI861684A0 (fi)	1986-04-22
HU195813B (en)	1988-07-28

Publication	Publication Date	Title
SE8601907D0 (sv)	1986-04-24	Imidazoquinoline antithrombogenic cardiotonic agents
IL73258A (en)	1987-11-30	6-(ar)alkyl-7-aminoazolo(1,5-a)pyrimidines,their preparation and their use as fungicides
DE3684299D1 (de)	1992-04-16	Neuartige verwendung von taurolin.
FI862757A0 (fi)	1986-06-27	Pyridonkarbonsyraderivat och foerfarande foer framstaellning av dessa.
ATE65993T1 (de)	1991-08-15	Chinolinverbindung.
ATE45354T1 (de)	1989-08-15	Chinoloncarbonsaeurederivate.
GR3002051T3 (en)	1992-12-30	3-oxadiazolyl and 3-carboxylic-acid beta-carboline derivatives, their preparation and their use as medicaments
ATE97899T1 (de)	1993-12-15	1,8-benzonaphthyridinderivate, ihre herstellung und diese enthaltende zusammensetzungen.
NO872382D0 (no)	1987-06-05	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser.
SE8502525D0 (sv)	1985-05-22	1,3-oxazolidine-2-one derivatives and processes for their preparation
ES2046229T3 (es)	1994-02-01	Composicion antiulcerosa.
FI842112A0 (fi)	1984-05-25	Foerfarande foer framstaellning av- karbolin-3-karboxylsyraderivat.
DE3778642D1 (de)	1992-06-04	Therapeutikum zur behandlung von magengeschwueren.
DE3374124D1 (de)	1987-11-26	5-phenylethenylbenzimidazoles
DK210387A (da)	1987-10-29	Heterocykliske forbindelser og fremgangsmaade til deres fremstilling samt farmaceutiske midler indeholdende disse
ES8307812A1 (es)	1983-08-01	Un procedimiento para la preparacion de nuevos amidin derivados del acido clavulawilo.
GR1000138B (el)	1991-09-27	Νεα παραγωγα ριβοφουρανουρονικου οξεος, μεθοδος δια την παρασευη αυτων και η χρησιμοποιησις αυτων.
ATE36536T1 (de)	1988-09-15	Phosphoroimidate.

Legal Events

Date	Code	Title	Description
1995-01-31	NUG	Patent has lapsed	Ref document number: 8601907-2 Effective date: 19941110 Format of ref document f/p: F

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