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SE8400450L - NEW CYCLIC DEPSIPEPTID ANTIBIOTIC, PROCEDURES FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE NEW ANTIBIOTIC - Google Patents

NEW CYCLIC DEPSIPEPTID ANTIBIOTIC, PROCEDURES FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE NEW ANTIBIOTIC

Info

Publication number
SE8400450L
SE8400450L SE8400450A SE8400450A SE8400450L SE 8400450 L SE8400450 L SE 8400450L SE 8400450 A SE8400450 A SE 8400450A SE 8400450 A SE8400450 A SE 8400450A SE 8400450 L SE8400450 L SE 8400450L
Authority
SE
Sweden
Prior art keywords
antibiotic
new
depsipeptid
procedures
preparing
Prior art date
Application number
SE8400450A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8400450D0 (en
SE464582B (en
Inventor
C A Claridge
H Schmitz
T W Doyle
M F Kammer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE8400450D0 publication Critical patent/SE8400450D0/en
Publication of SE8400450L publication Critical patent/SE8400450L/en
Publication of SE464582B publication Critical patent/SE464582B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A cyclic depsipeptide antibiotic designated luzopeptin E2 is produced by fermentation of Actinomedura luzonensis ATCC 31491 and isolation of the antibiotic free of substances coproduced therewith. Luzopeptin E2 exhibits antimicrobial activity and inhibits the growth of mammalian tumors.
SE8400450A 1983-01-31 1984-01-30 NEW CYCLEIC DEPSIPEPTID ANTIBIOTIC, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE NEW ANTIBIOTIC SE464582B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46257783A 1983-01-31 1983-01-31

Publications (3)

Publication Number Publication Date
SE8400450D0 SE8400450D0 (en) 1984-01-30
SE8400450L true SE8400450L (en) 1984-08-01
SE464582B SE464582B (en) 1991-05-13

Family

ID=23836950

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8400450A SE464582B (en) 1983-01-31 1984-01-30 NEW CYCLEIC DEPSIPEPTID ANTIBIOTIC, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE NEW ANTIBIOTIC

Country Status (15)

Country Link
JP (1) JPH0645638B2 (en)
KR (1) KR880001638B1 (en)
AU (1) AU566569B2 (en)
BE (1) BE898807A (en)
CA (1) CA1220746A (en)
CH (1) CH663415A5 (en)
DE (1) DE3403125A1 (en)
FR (1) FR2540116B1 (en)
GB (1) GB2134119B (en)
GR (1) GR81749B (en)
IT (1) IT1175927B (en)
MY (1) MY8800015A (en)
NL (1) NL8400237A (en)
SE (1) SE464582B (en)
ZA (1) ZA84613B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643871A (en) * 1993-11-23 1997-07-01 Bristol-Meyers Squibb Company Antitumor antibiotics
GB2294265A (en) * 1994-10-20 1996-04-24 Merck & Co Inc Cyclic depsipeptides obtained from Actinomycete sp.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2050384B (en) * 1979-04-02 1983-04-07 Bristol Myers Co Antitumor antibacterial agents

Also Published As

Publication number Publication date
IT1175927B (en) 1987-08-12
GB2134119B (en) 1986-04-30
ZA84613B (en) 1984-09-26
GB2134119A (en) 1984-08-08
CA1220746A (en) 1987-04-21
MY8800015A (en) 1988-12-31
CH663415A5 (en) 1987-12-15
JPH0645638B2 (en) 1994-06-15
SE8400450D0 (en) 1984-01-30
DE3403125A1 (en) 1984-10-31
KR880001638B1 (en) 1988-09-03
AU566569B2 (en) 1987-10-22
BE898807A (en) 1984-07-31
FR2540116B1 (en) 1989-08-18
SE464582B (en) 1991-05-13
NL8400237A (en) 1984-08-16
GR81749B (en) 1984-12-12
GB8402410D0 (en) 1984-02-29
KR840007106A (en) 1984-12-05
FR2540116A1 (en) 1984-08-03
JPS59173091A (en) 1984-09-29
IT8419348A0 (en) 1984-01-27
AU2372184A (en) 1984-08-02

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