SE8304315L - MOLDING ALKALOIDS, THEIR PREPARATION AND USE - Google Patents
MOLDING ALKALOIDS, THEIR PREPARATION AND USEInfo
- Publication number
- SE8304315L SE8304315L SE8304315A SE8304315A SE8304315L SE 8304315 L SE8304315 L SE 8304315L SE 8304315 A SE8304315 A SE 8304315A SE 8304315 A SE8304315 A SE 8304315A SE 8304315 L SE8304315 L SE 8304315L
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- alkaloids
- molding
- preparation
- agents
- Prior art date
Links
- 229930013930 alkaloid Natural products 0.000 title 1
- 238000000465 moulding Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 229940125684 antimigraine agent Drugs 0.000 abstract 1
- 239000002282 antimigraine agent Substances 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003568 thioethers Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
2-methyl-lysergyl ethers and thioethers are useful neuroleptics, anti-migraine agents, cerebral insufficiency agents, agents for senile dementia and anti-depressants. Preferably compounds of formula <IMAGE> where X is O or S, R1 is H, C1-4 alkyl or phenyl, R2 is C1-3 alkyl and R3 is phenyl or pyridyl, which may be substituted, or alkyl are used.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH4772/82A CH649998A5 (en) | 1982-08-09 | 1982-08-09 | ERGOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND HEALING AGENTS, CONTAINING THESE ERGOL DERIVATIVES AS AN ACTIVE SUBSTANCE. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8304315D0 SE8304315D0 (en) | 1983-08-08 |
| SE8304315L true SE8304315L (en) | 1984-02-10 |
Family
ID=4282273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8304315A SE8304315L (en) | 1982-08-09 | 1983-08-08 | MOLDING ALKALOIDS, THEIR PREPARATION AND USE |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5948480A (en) |
| AT (1) | AT383125B (en) |
| AU (1) | AU563736B2 (en) |
| BE (1) | BE897473A (en) |
| CA (1) | CA1215972A (en) |
| CH (1) | CH649998A5 (en) |
| DE (1) | DE3327705A1 (en) |
| DK (1) | DK361983A (en) |
| ES (1) | ES8502992A1 (en) |
| FI (1) | FI73679C (en) |
| FR (1) | FR2531433B1 (en) |
| GB (1) | GB2125041B (en) |
| GR (1) | GR78923B (en) |
| HU (1) | HU187600B (en) |
| IL (1) | IL69450A (en) |
| IT (1) | IT1168961B (en) |
| MY (1) | MY8700166A (en) |
| NL (1) | NL8302776A (en) |
| NZ (1) | NZ205181A (en) |
| PH (1) | PH20385A (en) |
| PT (1) | PT77168B (en) |
| SE (1) | SE8304315L (en) |
| ZA (1) | ZA835850B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4675322A (en) * | 1984-12-10 | 1987-06-23 | Eli Lilly And Company | 1-Substituted-6-n-propyl-8β-methylthio-methylergolines |
| HU193782B (en) * | 1985-06-21 | 1987-11-30 | Richter Gedeon Vegyeszet | Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof |
| FR2589734B1 (en) * | 1985-11-13 | 1988-09-02 | Roussel Uclaf | USE OF ERGOLIN DERIVATIVES FOR OBTAINING A GERIATRIC MEDICINE |
| US4798834A (en) * | 1987-08-31 | 1989-01-17 | Eli Lilly And Company | Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement |
| DE3913756A1 (en) * | 1989-04-21 | 1990-10-25 | Schering Ag | 8 (BETA) SUBSTITUTED ERGOLINE, METHOD FOR THE PRODUCTION AND USE THEREOF |
| DE10212564B4 (en) * | 2002-03-12 | 2007-04-19 | Neurobiotec Gmbh | 1-Allyl ergot alkaloid derivatives and their use for the prophylaxis and treatment of migraine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE41533B1 (en) * | 1974-03-14 | 1980-01-30 | Sandoz Ltd | Thiomethyl ergolene derivatives |
| US3901894A (en) * | 1974-06-06 | 1975-08-26 | Lilly Co Eli | 8-thiomethylergolines |
| US3959288A (en) * | 1974-12-13 | 1976-05-25 | Eli Lilly And Company | 8-Oxymethylergolines and process therefor |
| US4166182A (en) * | 1978-02-08 | 1979-08-28 | Eli Lilly And Company | 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds |
| US4382940A (en) * | 1979-12-06 | 1983-05-10 | Farmitalia Carlo Erba S.P.A. | Ercoline derivatives and therapeutic compositions having CNS affecting activity |
-
1982
- 1982-08-09 CH CH4772/82A patent/CH649998A5/en not_active IP Right Cessation
-
1983
- 1983-08-01 DE DE19833327705 patent/DE3327705A1/en not_active Withdrawn
- 1983-08-02 FI FI832789A patent/FI73679C/en not_active IP Right Cessation
- 1983-08-04 FR FR8313018A patent/FR2531433B1/en not_active Expired
- 1983-08-05 NL NL8302776A patent/NL8302776A/en not_active Application Discontinuation
- 1983-08-05 BE BE1/10847A patent/BE897473A/en not_active IP Right Cessation
- 1983-08-05 GB GB08321222A patent/GB2125041B/en not_active Expired
- 1983-08-08 DK DK361983A patent/DK361983A/en unknown
- 1983-08-08 SE SE8304315A patent/SE8304315L/en not_active Application Discontinuation
- 1983-08-08 AU AU17672/83A patent/AU563736B2/en not_active Expired - Fee Related
- 1983-08-08 JP JP58144843A patent/JPS5948480A/en active Pending
- 1983-08-08 PT PT77168A patent/PT77168B/en unknown
- 1983-08-08 AT AT0286383A patent/AT383125B/en not_active IP Right Cessation
- 1983-08-08 HU HU832798A patent/HU187600B/en unknown
- 1983-08-08 CA CA000434064A patent/CA1215972A/en not_active Expired
- 1983-08-08 IL IL69450A patent/IL69450A/en unknown
- 1983-08-08 ES ES524815A patent/ES8502992A1/en not_active Expired
- 1983-08-08 NZ NZ205181A patent/NZ205181A/en unknown
- 1983-08-08 GR GR72165A patent/GR78923B/el unknown
- 1983-08-09 IT IT22490/83A patent/IT1168961B/en active
- 1983-08-09 ZA ZA835850A patent/ZA835850B/en unknown
- 1983-08-09 PH PH29378A patent/PH20385A/en unknown
-
1987
- 1987-12-30 MY MY166/87A patent/MY8700166A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH20385A (en) | 1986-12-08 |
| NL8302776A (en) | 1984-03-01 |
| ZA835850B (en) | 1985-03-27 |
| IL69450A (en) | 1986-10-31 |
| GB2125041B (en) | 1986-04-23 |
| CH649998A5 (en) | 1985-06-28 |
| IL69450A0 (en) | 1983-11-30 |
| JPS5948480A (en) | 1984-03-19 |
| ES524815A0 (en) | 1985-02-01 |
| ES8502992A1 (en) | 1985-02-01 |
| FI73679B (en) | 1987-07-31 |
| DE3327705A1 (en) | 1984-02-09 |
| GR78923B (en) | 1984-10-02 |
| BE897473A (en) | 1984-02-06 |
| AU1767283A (en) | 1984-02-16 |
| GB2125041A (en) | 1984-02-29 |
| SE8304315D0 (en) | 1983-08-08 |
| GB8321222D0 (en) | 1983-09-07 |
| AU563736B2 (en) | 1987-07-23 |
| FR2531433A1 (en) | 1984-02-10 |
| FI832789L (en) | 1984-02-10 |
| IT8322490A0 (en) | 1983-08-09 |
| NZ205181A (en) | 1986-07-11 |
| ATA286383A (en) | 1986-10-15 |
| CA1215972A (en) | 1986-12-30 |
| AT383125B (en) | 1987-05-25 |
| DK361983A (en) | 1984-02-10 |
| IT1168961B (en) | 1987-05-20 |
| MY8700166A (en) | 1987-12-31 |
| PT77168A (en) | 1983-09-01 |
| FR2531433B1 (en) | 1985-10-18 |
| FI73679C (en) | 1987-11-09 |
| PT77168B (en) | 1986-03-27 |
| DK361983D0 (en) | 1983-08-08 |
| HU187600B (en) | 1986-01-28 |
| FI832789A0 (en) | 1983-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 8304315-8 |