SE8101205L - Nya iminiumsalter och forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on - Google Patents

Nya iminiumsalter och forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on

Info

Publication number: SE8101205L
Authority: SE; Sweden
Prior art keywords: carbamyl; cyano; bipyridine; procedures; preparation
Prior art date: 1980-02-26

Application number

SE8101205A

Other languages

English (en)

Other versions

SE437514B (sv

Inventor

K O Gelotte

Jr C J Opalka

Original Assignee

Sterling Drug Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-26

Filing date

1981-02-24

Publication date

1981-08-27

1981-02-24 Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc

1981-08-27 Publication of SE8101205L publication Critical patent/SE8101205L/sv

1985-03-04 Publication of SE437514B publication Critical patent/SE437514B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SE8101205A 1980-02-26 1981-02-24 N-/3-dimetylamino-2-(4-pyridinyl)-2-propenyliden/-n-metylmetaniminiumsalt, sett att framstella detta och kardioton komposition for okning av hjertkontraktiliteten SE437514B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/124,808 US4264609A (en)	1980-02-26	1980-02-26	N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic

Publications (2)

Publication Number	Publication Date
SE8101205L true SE8101205L (sv)	1981-08-27
SE437514B SE437514B (sv)	1985-03-04

Family

ID=22416880

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE8101205A SE437514B (sv)	1980-02-26	1981-02-24	N-/3-dimetylamino-2-(4-pyridinyl)-2-propenyliden/-n-metylmetaniminiumsalt, sett att framstella detta och kardioton komposition for okning av hjertkontraktiliteten
SE8402727A SE452764B (sv)	1980-02-26	1984-05-21	Forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE8402727A SE452764B (sv)	1980-02-26	1984-05-21	Forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on

Country Status (28)

Country	Link
US (1)	US4264609A (sv)
JP (1)	JPS56128758A (sv)
KR (2)	KR840002067B1 (sv)
AR (1)	AR230630A1 (sv)
AT (2)	AT380237B (sv)
AU (1)	AU541644B2 (sv)
BE (1)	BE887663A (sv)
CA (1)	CA1128523A (sv)
CH (1)	CH647509A5 (sv)
DE (1)	DE3107306A1 (sv)
DK (1)	DK171253B1 (sv)
ES (1)	ES499776A1 (sv)
FI (1)	FI76787C (sv)
FR (1)	FR2476646A1 (sv)
GB (1)	GB2070600B (sv)
HK (1)	HK71789A (sv)
IE (1)	IE51696B1 (sv)
IL (1)	IL62161A (sv)
IT (1)	IT1210992B (sv)
LU (1)	LU83169A1 (sv)
MX (1)	MX6908E (sv)
NL (1)	NL192109C (sv)
NO (1)	NO156689C (sv)
NZ (1)	NZ196282A (sv)
PH (2)	PH19904A (sv)
PT (1)	PT72573B (sv)
SE (2)	SE437514B (sv)
ZA (1)	ZA811124B (sv)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0200024B1 (de)	1985-04-30	1992-07-01	ARZNEIMITTELWERK DRESDEN GmbH	3-Cyan-pyridine, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4004012A (en) *	1975-10-14	1977-01-18	Sterling Drug Inc.	3-Cyano-5-(pyridinyl)-2(1H)-pyridinones
US4072746A (en) *	1975-10-14	1978-02-07	Sterling Drug Inc.	3-Amino-5-(pyridinyl)-2(1H)-pyridinones

1980
- 1980-02-26 US US06/124,808 patent/US4264609A/en not_active Expired - Lifetime
1981
- 1981-02-17 NZ NZ196282A patent/NZ196282A/xx unknown
- 1981-02-18 IL IL62161A patent/IL62161A/xx not_active IP Right Cessation
- 1981-02-20 AU AU67487/81A patent/AU541644B2/en not_active Expired
- 1981-02-20 GB GB8105369A patent/GB2070600B/en not_active Expired
- 1981-02-20 ZA ZA00811124A patent/ZA811124B/xx unknown
- 1981-02-24 FR FR8103609A patent/FR2476646A1/fr active Granted
- 1981-02-24 PH PH25258A patent/PH19904A/en unknown
- 1981-02-24 IT IT8119952A patent/IT1210992B/it active
- 1981-02-24 CH CH1222/81A patent/CH647509A5/fr not_active IP Right Cessation
- 1981-02-24 SE SE8101205A patent/SE437514B/sv not_active IP Right Cessation
- 1981-02-25 KR KR1019810000616A patent/KR840002067B1/ko not_active Expired
- 1981-02-25 AT AT0088581A patent/AT380237B/de not_active IP Right Cessation
- 1981-02-25 FI FI810582A patent/FI76787C/sv not_active IP Right Cessation
- 1981-02-25 DK DK083981A patent/DK171253B1/da not_active IP Right Cessation
- 1981-02-25 NL NL8100922A patent/NL192109C/nl not_active IP Right Cessation
- 1981-02-25 BE BE1/10150A patent/BE887663A/fr not_active IP Right Cessation
- 1981-02-25 ES ES499776A patent/ES499776A1/es not_active Expired
- 1981-02-25 CA CA371,690A patent/CA1128523A/en not_active Expired
- 1981-02-25 MX MX819321U patent/MX6908E/es unknown
- 1981-02-25 NO NO810639A patent/NO156689C/no unknown
- 1981-02-25 PT PT72573A patent/PT72573B/pt unknown
- 1981-02-25 IE IE397/81A patent/IE51696B1/en not_active IP Right Cessation
- 1981-02-26 DE DE19813107306 patent/DE3107306A1/de active Granted
- 1981-02-26 AR AR284447A patent/AR230630A1/es active
- 1981-02-26 JP JP2759981A patent/JPS56128758A/ja active Granted
- 1981-02-26 LU LU83169A patent/LU83169A1/fr unknown
1982
- 1982-03-01 PH PH26927A patent/PH17145A/en unknown
1983
- 1983-08-26 AT AT0305683A patent/AT380236B/de not_active IP Right Cessation
1984
- 1984-05-21 SE SE8402727A patent/SE452764B/sv not_active IP Right Cessation
- 1984-08-22 KR KR1019840005058A patent/KR840002066B1/ko not_active Expired
1989
- 1989-09-07 HK HK717/89A patent/HK71789A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT72573A (pt)	1981-03-01
DK83981A (da)	1981-08-27
GB2070600B (en)	1984-07-11
IT1210992B (it)	1989-09-29
MX6908E (es)	1986-11-07
ZA811124B (en)	1982-03-31
IT8119952A0 (it)	1981-02-24
ATA305683A (de)	1985-09-15
FR2476646A1 (fr)	1981-08-28
JPS56128758A (en)	1981-10-08
IE810397L (en)	1981-08-26
GB2070600A (en)	1981-09-09
FI76787C (sv)	1988-12-12
SE452764B (sv)	1987-12-14
BE887663A (fr)	1981-08-25
LU83169A1 (fr)	1981-09-11
AU6748781A (en)	1981-09-03
AR230630A1 (es)	1984-05-31
NZ196282A (en)	1983-12-16
IL62161A0 (en)	1981-03-31
DE3107306C2 (sv)	1990-11-29
FI76787B (fi)	1988-08-31
IE51696B1 (en)	1987-02-18
NO810639L (no)	1981-08-27
FR2476646B1 (sv)	1984-08-17
DK171253B1 (da)	1996-08-12
AT380236B (de)	1986-04-25
JPH0141626B2 (sv)	1989-09-06
NL192109B (nl)	1996-10-01
CA1128523A (en)	1982-07-27
ATA88581A (de)	1985-09-15
KR830005143A (ko)	1983-08-03
DE3107306A1 (de)	1981-12-17
NL8100922A (nl)	1981-09-16
AT380237B (de)	1986-04-25
FI810582L (fi)	1981-08-27
CH647509A5 (fr)	1985-01-31
SE437514B (sv)	1985-03-04
HK71789A (en)	1989-09-14
IL62161A (en)	1984-06-29
PH17145A (en)	1984-06-04
ES499776A1 (es)	1984-06-16
AU541644B2 (en)	1985-01-17
KR840002066B1 (ko)	1984-11-09
US4264609A (en)	1981-04-28
SE8402727L (sv)	1984-05-21
KR840002067B1 (ko)	1984-11-09
NL192109C (nl)	1997-02-04
PH19904A (en)	1986-08-13
SE8402727D0 (sv)	1984-05-21
NO156689C (no)	1987-11-04
NO156689B (no)	1987-07-27
PT72573B (en)	1982-02-12

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ES2343316T3 (es)	2010-07-28	Derivados de piridina inhibidores de la cox-2.
SE8102022L (sv)	1981-03-30	Intermediat i form av 2(ih)-pyridinoner samt forfarande for framstellning derav
GB1088531A (en)	1967-10-25	Substituted benzamides
EP0303697A1 (en)	1989-02-22	Derivatives of physiologically active substance k-252
JP7219902B2 (ja)	2023-02-09	ブルトン型チロシンキナーゼ阻害剤
JP2008517956A (ja)	2008-05-29	二重の抗血小板性／抗凝固性ピリドキシン類似体
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ES8507112A1 (es)	1985-08-16	Un procedimiento para la prpeparacion de compuestos de 1,4-dihidropiridina.
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SE8101205L (sv)	1981-08-27	Nya iminiumsalter och forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on
NO832784L (no)	1984-02-03	5-(lavere-alkyl)-1,6-nafthyridin-2(1h)-on-forbindelser og fremgangsmaate for deres fremstilling
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US4156004A (en)	1979-05-22	Substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines, and use

Legal Events

Date	Code	Title	Description
1995-01-31	NAL	Patent in force	Ref document number: 8101205-6 Format of ref document f/p: F
2001-04-23	NUG	Patent has lapsed	Ref document number: 8101205-6 Format of ref document f/p: F

Date

Code

Title

Description

1995-01-31

NAL

Patent in force

Ref document number: 8101205-6

Format of ref document f/p: F

2001-04-23

NUG

Patent has lapsed