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RU2261088C2 - Фосфолипидный гель - Google Patents

Фосфолипидный гель Download PDF

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Publication number
RU2261088C2
RU2261088C2 RU2002104972/15A RU2002104972A RU2261088C2 RU 2261088 C2 RU2261088 C2 RU 2261088C2 RU 2002104972/15 A RU2002104972/15 A RU 2002104972/15A RU 2002104972 A RU2002104972 A RU 2002104972A RU 2261088 C2 RU2261088 C2 RU 2261088C2
Authority
RU
Russia
Prior art keywords
phospholipid
gel
gel according
alcohol
buffer
Prior art date
Application number
RU2002104972/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2002104972A (ru
Inventor
Бернд ИБШЕР (DE)
Бернд ИБШЕР
Руланд ФРИДРИХ (DE)
Руланд ФРИДРИХ
Original Assignee
Меркле Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Меркле Гмбх filed Critical Меркле Гмбх
Publication of RU2002104972A publication Critical patent/RU2002104972A/ru
Application granted granted Critical
Publication of RU2261088C2 publication Critical patent/RU2261088C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0052Preparation of gels
    • B01J13/0065Preparation of gels containing an organic phase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2002104972/15A 1999-08-25 2000-08-16 Фосфолипидный гель RU2261088C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19940227 1999-08-25
DE19940227.2 1999-08-25
DE19940227A DE19940227A1 (de) 1999-08-25 1999-08-25 Phospholipidgel

Publications (2)

Publication Number Publication Date
RU2002104972A RU2002104972A (ru) 2003-11-10
RU2261088C2 true RU2261088C2 (ru) 2005-09-27

Family

ID=7919498

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002104972/15A RU2261088C2 (ru) 1999-08-25 2000-08-16 Фосфолипидный гель

Country Status (13)

Country Link
EP (1) EP1206245A2 (de)
JP (1) JP2003507408A (de)
AU (1) AU776766B2 (de)
CA (1) CA2381571A1 (de)
CZ (1) CZ2002561A3 (de)
DE (1) DE19940227A1 (de)
HU (1) HUP0203097A3 (de)
NO (1) NO20020768L (de)
PL (1) PL353215A1 (de)
RU (1) RU2261088C2 (de)
SK (1) SK2442002A3 (de)
WO (1) WO2001013887A2 (de)
ZA (1) ZA200201506B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002062316A1 (de) * 2001-02-08 2002-08-15 Vectron Therapeutics Ag Invasomen zur therapie von erkrankungen, ihre herstellung und verwendung
CN1335182A (zh) * 2001-08-08 2002-02-13 华中科技大学 胰岛素口腔喷剂及其制备工艺
DE10255285A1 (de) * 2002-11-26 2004-06-03 Mcs Micro Carrier Systems Gmbh Selbst formende Phospholipid-Gele
DE10255195A1 (de) * 2002-11-27 2004-06-09 Lipoid Gmbh Micellare wasserlösliche Konzentrate
ATE385779T1 (de) * 2002-12-20 2008-03-15 Idexx Lab Inc Dicolfenac-haltige liposomale schmerzstillende formulierung und ihre verwendung zur behandlung von pferden
US7858115B2 (en) 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
FI20065222A7 (fi) * 2006-04-05 2007-10-06 Finnfeeds Finland Oy Inositolin käyttö
RU2309738C1 (ru) * 2006-08-28 2007-11-10 Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") Фармацевтический состав с противовоспалительным и обезболивающим действием и способ его получения
ITMI20081862A1 (it) * 2008-10-21 2010-04-22 Funziona Srl Composizione ad uso topico per il trattamento delle adiposita' localizzate e dei relativi inestetismi
EP2355803A4 (de) * 2008-11-14 2012-04-25 Archer Daniels Midland Co Organogel-zusammensetzungen und herstellungsverfahren
EP2210589B1 (de) * 2009-01-22 2015-05-06 Ludwig-Maximilians-Universität München Vesikuläre Phospholipid-Gele mit proteinösen Substanzen
BE1018506A3 (nl) * 2009-02-26 2011-02-01 Bogaert Gina Van Samenstelling van een hydrocortisone, zijn derivaten, metabolieten, prodrugs of mengsels daarvan houdende liposomale gel en het gebruik ervan.
SG185499A1 (en) * 2010-05-14 2012-12-28 Archer Daniels Midland Co Food compositions comprising organogels
JP2017214299A (ja) * 2016-05-30 2017-12-07 ライオン株式会社 半固形製剤及びその製造方法
CN110891610B (zh) 2017-03-23 2024-03-01 脂类系统股份公司 亲水性化合物在单层脂质体中的高效包封

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158441A2 (de) * 1984-03-08 1985-10-16 Phares Pharmaceutical Holland B.V. Liposombildende Zusammensetzung
WO1990012565A1 (en) * 1989-04-25 1990-11-01 Nattermann, A. & Cie. Gmbh Water-containing formulations with phospholipids
DE4021082A1 (de) * 1990-07-03 1992-01-23 Hans Dr Lautenschlaeger Hautbehandlungsmittel mit hohen lipidgehalten unter verwendung eines bilayer enthaltenden systems, salzen organischer saeuren, alkohol und stabilisator
DE19520659A1 (de) * 1995-06-09 1996-12-12 Mika Pharma Ges Fuer Die Entwi Pharmazeutische Zubereitung zur Therapie und/oder Prophylaxe von durch Viren bedingten Erkrankungen der Haut und/oder der Schleimhaut
RU2128502C1 (ru) * 1994-06-08 1999-04-10 Л'Ореаль Косметическая или дерматологическая композиция для местного применения в форме водной и стабильной дисперсии частиц кубического геля и ее применение

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2501336B2 (ja) * 1987-07-02 1996-05-29 第一製薬株式会社 安定なリポソ−ム製剤
US5820848A (en) * 1990-01-12 1998-10-13 The Liposome Company, Inc. Methods of preparing interdigitation-fusion liposomes and gels which encapsulate a bioactive agent
DE4003783C2 (de) * 1990-02-08 1999-03-25 Nattermann A & Cie Phospholipidhaltiges Gel, Verfahren zu dessen Herstellung und Verwendung
DE19719604A1 (de) * 1997-05-09 1998-07-16 Henkel Kgaa Färbemittel für Keratinfasern

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158441A2 (de) * 1984-03-08 1985-10-16 Phares Pharmaceutical Holland B.V. Liposombildende Zusammensetzung
WO1990012565A1 (en) * 1989-04-25 1990-11-01 Nattermann, A. & Cie. Gmbh Water-containing formulations with phospholipids
DE4021082A1 (de) * 1990-07-03 1992-01-23 Hans Dr Lautenschlaeger Hautbehandlungsmittel mit hohen lipidgehalten unter verwendung eines bilayer enthaltenden systems, salzen organischer saeuren, alkohol und stabilisator
RU2128502C1 (ru) * 1994-06-08 1999-04-10 Л'Ореаль Косметическая или дерматологическая композиция для местного применения в форме водной и стабильной дисперсии частиц кубического геля и ее применение
DE19520659A1 (de) * 1995-06-09 1996-12-12 Mika Pharma Ges Fuer Die Entwi Pharmazeutische Zubereitung zur Therapie und/oder Prophylaxe von durch Viren bedingten Erkrankungen der Haut und/oder der Schleimhaut

Also Published As

Publication number Publication date
DE19940227A1 (de) 2001-03-08
JP2003507408A (ja) 2003-02-25
CA2381571A1 (en) 2001-03-01
CZ2002561A3 (cs) 2002-07-17
EP1206245A2 (de) 2002-05-22
ZA200201506B (en) 2003-05-28
WO2001013887A2 (de) 2001-03-01
WO2001013887A3 (de) 2001-09-20
NO20020768D0 (no) 2002-02-15
AU7276700A (en) 2001-03-19
HUP0203097A2 (hu) 2003-01-28
AU776766B2 (en) 2004-09-23
SK2442002A3 (en) 2002-08-06
PL353215A1 (en) 2003-11-03
NO20020768L (no) 2002-02-15
HUP0203097A3 (en) 2006-11-28

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Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20060817