RU2018109295A3 - - Google Patents
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- Publication number
- RU2018109295A3 RU2018109295A3 RU2018109295A RU2018109295A RU2018109295A3 RU 2018109295 A3 RU2018109295 A3 RU 2018109295A3 RU 2018109295 A RU2018109295 A RU 2018109295A RU 2018109295 A RU2018109295 A RU 2018109295A RU 2018109295 A3 RU2018109295 A3 RU 2018109295A3
- Authority
- RU
- Russia
Links
Classifications
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01R—ELECTRICALLY-CONDUCTIVE CONNECTIONS; STRUCTURAL ASSOCIATIONS OF A PLURALITY OF MUTUALLY-INSULATED ELECTRICAL CONNECTING ELEMENTS; COUPLING DEVICES; CURRENT COLLECTORS
- H01R12/00—Structural associations of a plurality of mutually-insulated electrical connecting elements, specially adapted for printed circuits, e.g. printed circuit boards [PCB], flat or ribbon cables, or like generally planar structures, e.g. terminal strips, terminal blocks; Coupling devices specially adapted for printed circuits, flat or ribbon cables, or like generally planar structures; Terminals specially adapted for contact with, or insertion into, printed circuits, flat or ribbon cables, or like generally planar structures
- H01R12/50—Fixed connections
- H01R12/51—Fixed connections for rigid printed circuits or like structures
- H01R12/55—Fixed connections for rigid printed circuits or like structures characterised by the terminals
- H01R12/58—Fixed connections for rigid printed circuits or like structures characterised by the terminals terminals for insertion into holes
- H01R12/585—Terminals having a press fit or a compliant portion and a shank passing through a hole in the printed circuit board
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K1/00—Printed circuits
- H05K1/02—Details
- H05K1/0201—Thermal arrangements, e.g. for cooling, heating or preventing overheating
- H05K1/0203—Cooling of mounted components
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K1/00—Printed circuits
- H05K1/02—Details
- H05K1/11—Printed elements for providing electric connections to or between printed circuits
- H05K1/115—Via connections; Lands around holes or via connections
- H05K1/116—Lands, clearance holes or other lay-out details concerning the surrounding of a via
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K1/00—Printed circuits
- H05K1/18—Printed circuits structurally associated with non-printed electric components
- H05K1/181—Printed circuits structurally associated with non-printed electric components associated with surface mounted components
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polyamides (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261705731P | 2012-09-26 | 2012-09-26 | |
| US61/705,731 | 2012-09-26 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015111635A Division RU2648992C2 (ru) | 2012-09-26 | 2013-09-26 | Улучшенные способы ацилирования майтанзинола |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2022101074A Division RU2022101074A (ru) | 2022-01-18 | Улучшенные способы ацилирования майтанзинола |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2018109295A RU2018109295A (ru) | 2019-02-26 |
| RU2018109295A3 true RU2018109295A3 (ru) | 2021-06-24 |
| RU2765072C2 RU2765072C2 (ru) | 2022-01-25 |
Family
ID=49328648
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015111635A RU2648992C2 (ru) | 2012-09-26 | 2013-09-26 | Улучшенные способы ацилирования майтанзинола |
| RU2018109295A RU2765072C2 (ru) | 2012-09-26 | 2013-09-26 | Улучшенные способы ацилирования майтанзинола |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015111635A RU2648992C2 (ru) | 2012-09-26 | 2013-09-26 | Улучшенные способы ацилирования майтанзинола |
Country Status (27)
| Country | Link |
|---|---|
| US (9) | US9012629B2 (ru) |
| EP (3) | EP3904358A1 (ru) |
| JP (7) | JP6517693B2 (ru) |
| CN (2) | CN108586487B (ru) |
| AU (4) | AU2013323572B2 (ru) |
| BR (2) | BR112015006505B1 (ru) |
| CA (2) | CA3133906C (ru) |
| CY (2) | CY1121415T1 (ru) |
| DK (2) | DK3486248T3 (ru) |
| ES (2) | ES2716561T3 (ru) |
| HR (2) | HRP20190473T1 (ru) |
| HU (2) | HUE055443T2 (ru) |
| IL (2) | IL237899A (ru) |
| LT (2) | LT3486248T (ru) |
| MX (2) | MX390615B (ru) |
| MY (1) | MY169250A (ru) |
| NZ (2) | NZ739573A (ru) |
| PL (2) | PL3486248T3 (ru) |
| PT (2) | PT3486248T (ru) |
| RS (2) | RS58493B1 (ru) |
| RU (2) | RU2648992C2 (ru) |
| SG (1) | SG11201501918UA (ru) |
| SI (2) | SI2900676T1 (ru) |
| SM (2) | SMT201900170T1 (ru) |
| TR (1) | TR201903625T4 (ru) |
| WO (1) | WO2014052537A1 (ru) |
| ZA (1) | ZA201501898B (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20190473T1 (hr) * | 2012-09-26 | 2019-05-03 | Immunogen, Inc. | Poboljšani postupci za aciliranje majtanzinola |
| CN105585579A (zh) * | 2014-10-24 | 2016-05-18 | 南京联宁生物制药有限公司 | 一种化合物及其制备方法以及美登素dm1的制备方法 |
| WO2016149464A1 (en) * | 2015-03-17 | 2016-09-22 | Regeneron Pharmaceuticals, Inc. | Amino acid acylation reagents and methods of using the same |
| WO2018112334A1 (en) | 2016-12-16 | 2018-06-21 | Bluefin Biomedicine, Inc. | Anti-cub domain-containing protein 1 (cdcp1) antibodies, antibody drug conjugates, and methods of use thereof |
| ES2942915T3 (es) | 2019-04-18 | 2023-06-07 | Indena Spa | Procedimiento diasteroselectivo para la preparación de ésteres de maitansinoides que contienen tiol o disulfuro y sus intermedios |
| JP7772363B2 (ja) | 2019-11-29 | 2025-11-18 | 日本マイクロバイオファーマ株式会社 | メイタンシノールの酵素的生産方法 |
| WO2024225377A1 (ja) | 2023-04-28 | 2024-10-31 | 中外製薬株式会社 | Ｎ－カルボキシアミノ酸無水物を用いたアミド基含有化合物の製造方法 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4151042A (en) | 1977-03-31 | 1979-04-24 | Takeda Chemical Industries, Ltd. | Method for producing maytansinol and its derivatives |
| JPS6034556B2 (ja) * | 1977-03-31 | 1985-08-09 | 武田薬品工業株式会社 | 抗生物質ｃ−１５００３ |
| US4137230A (en) | 1977-11-14 | 1979-01-30 | Takeda Chemical Industries, Ltd. | Method for the production of maytansinoids |
| US4265814A (en) | 1978-03-24 | 1981-05-05 | Takeda Chemical Industries | Matansinol 3-n-hexadecanoate |
| JPS5562090A (en) | 1978-10-27 | 1980-05-10 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| JPS5566585A (en) | 1978-11-14 | 1980-05-20 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| JPS55164687A (en) | 1979-06-11 | 1980-12-22 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| JPS55162791A (en) | 1979-06-05 | 1980-12-18 | Takeda Chem Ind Ltd | Antibiotic c-15003pnd and its preparation |
| JPS55164685A (en) | 1979-06-08 | 1980-12-22 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| JPS55164686A (en) | 1979-06-11 | 1980-12-22 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| US4309428A (en) | 1979-07-30 | 1982-01-05 | Takeda Chemical Industries, Ltd. | Maytansinoids |
| JPS5622790A (en) * | 1979-07-31 | 1981-03-03 | Takeda Chem Ind Ltd | Novel maytansinoid compound and its preparation |
| JPS5645483A (en) | 1979-09-19 | 1981-04-25 | Takeda Chem Ind Ltd | C-15003phm and its preparation |
| JP3054741B2 (ja) * | 1989-09-29 | 2000-06-19 | 武田薬品工業株式会社 | Ｔａｎ―１３１３およびそのアシル誘導体 |
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| EP2289549A3 (en) * | 1999-10-01 | 2011-06-15 | Immunogen, Inc. | Immunoconjugates for treating cancer |
| US6441163B1 (en) | 2001-05-31 | 2002-08-27 | Immunogen, Inc. | Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents |
| TWI298067B (en) * | 2002-01-31 | 2008-06-21 | Daiso Co Ltd | New optically active compound, method for kinetic resolution of carbonic acid derivatives and catalyst thereof |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| SI1651162T1 (sl) * | 2003-05-20 | 2016-02-29 | Immunogen, Inc. | Izboljšani citotoksični agenti, ki vsebujejo nove majtanzinoide |
| EP1663107A4 (en) * | 2003-08-22 | 2010-06-23 | Activbiotics Pharma Llc | RIFAMYCIN ANALOGS AND USES THEREOF |
| KR101270829B1 (ko) | 2004-09-23 | 2013-06-07 | 제넨테크, 인크. | 시스테인 유전자조작 항체 및 접합체 |
| PT1819359E (pt) | 2004-12-09 | 2015-05-28 | Janssen Biotech Inc | Imunoconjugados anti-integrina, métodos para a sua produção e sua utilização |
| US7301019B2 (en) * | 2005-01-21 | 2007-11-27 | Immunogen, Inc. | Method for the preparation of maytansinoid esters |
| WO2007011721A1 (en) * | 2005-07-15 | 2007-01-25 | Kalypsys, Inc. | Inhibitors of mitotic kinesin |
| AU2006280146B2 (en) * | 2005-08-09 | 2012-06-28 | Immunogen, Inc. | Method of acylating maytansinol with chiral amino acids |
| WO2008057511A2 (en) * | 2006-11-06 | 2008-05-15 | Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Ascomycin and pimecrolimus having reduced levels of desmethylascomycin and 32-deoxy-32-epichloro-desmethylascomycin respectively, and methods for preparation thereof |
| JP2008288289A (ja) | 2007-05-16 | 2008-11-27 | Oki Electric Ind Co Ltd | 電界効果トランジスタとその製造方法 |
| SG176068A1 (en) | 2009-06-03 | 2011-12-29 | Immunogen Inc | Conjugation methods |
| EP2480557A2 (en) * | 2009-09-25 | 2012-08-01 | Cadila Healthcare Limited | Process for the preparation of rapamycin derivatives |
| CN103313990B (zh) * | 2010-11-17 | 2016-07-20 | 基因泰克公司 | 丙氨酰美登醇抗体偶联物 |
| HRP20190473T1 (hr) | 2012-09-26 | 2019-05-03 | Immunogen, Inc. | Poboljšani postupci za aciliranje majtanzinola |
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2013
- 2013-09-26 HR HRP20190473TT patent/HRP20190473T1/hr unknown
- 2013-09-26 SM SM20190170T patent/SMT201900170T1/it unknown
- 2013-09-26 PL PL18213678T patent/PL3486248T3/pl unknown
- 2013-09-26 SM SM20210390T patent/SMT202100390T1/it unknown
- 2013-09-26 RS RS20190314A patent/RS58493B1/sr unknown
- 2013-09-26 CA CA3133906A patent/CA3133906C/en active Active
- 2013-09-26 PT PT182136788T patent/PT3486248T/pt unknown
- 2013-09-26 ES ES13774881T patent/ES2716561T3/es active Active
- 2013-09-26 TR TR2019/03625T patent/TR201903625T4/tr unknown
- 2013-09-26 CN CN201810251853.0A patent/CN108586487B/zh active Active
- 2013-09-26 US US14/037,657 patent/US9012629B2/en active Active
- 2013-09-26 PL PL13774881T patent/PL2900676T3/pl unknown
- 2013-09-26 DK DK18213678.8T patent/DK3486248T3/da active
- 2013-09-26 RU RU2015111635A patent/RU2648992C2/ru active
- 2013-09-26 SI SI201331374T patent/SI2900676T1/sl unknown
- 2013-09-26 MY MYPI2015000663A patent/MY169250A/en unknown
- 2013-09-26 SI SI201331899T patent/SI3486248T1/sl unknown
- 2013-09-26 WO PCT/US2013/061839 patent/WO2014052537A1/en not_active Ceased
- 2013-09-26 LT LTEP18213678.8T patent/LT3486248T/lt unknown
- 2013-09-26 EP EP21166484.2A patent/EP3904358A1/en active Pending
- 2013-09-26 HU HUE18213678A patent/HUE055443T2/hu unknown
- 2013-09-26 RS RS20210825A patent/RS62075B1/sr unknown
- 2013-09-26 PT PT13774881T patent/PT2900676T/pt unknown
- 2013-09-26 RU RU2018109295A patent/RU2765072C2/ru active
- 2013-09-26 SG SG11201501918UA patent/SG11201501918UA/en unknown
- 2013-09-26 DK DK13774881.0T patent/DK2900676T3/en active
- 2013-09-26 BR BR112015006505-8A patent/BR112015006505B1/pt active IP Right Grant
- 2013-09-26 AU AU2013323572A patent/AU2013323572B2/en active Active
- 2013-09-26 BR BR122021022582-6A patent/BR122021022582B1/pt active IP Right Grant
- 2013-09-26 EP EP18213678.8A patent/EP3486248B1/en active Active
- 2013-09-26 HU HUE13774881A patent/HUE043285T2/hu unknown
- 2013-09-26 ES ES18213678T patent/ES2880754T3/es active Active
- 2013-09-26 MX MX2019008652A patent/MX390615B/es unknown
- 2013-09-26 CA CA2884873A patent/CA2884873C/en active Active
- 2013-09-26 EP EP13774881.0A patent/EP2900676B1/en active Active
- 2013-09-26 JP JP2015534641A patent/JP6517693B2/ja active Active
- 2013-09-26 LT LTEP13774881.0T patent/LT2900676T/lt unknown
- 2013-09-26 NZ NZ73957313A patent/NZ739573A/en unknown
- 2013-09-26 MX MX2015003745A patent/MX366701B/es active IP Right Grant
- 2013-09-26 CN CN201380049853.8A patent/CN104768955B/zh active Active
- 2013-09-26 NZ NZ706019A patent/NZ706019A/en unknown
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2015
- 2015-03-17 US US14/660,050 patent/US9469655B2/en active Active
- 2015-03-19 ZA ZA2015/01898A patent/ZA201501898B/en unknown
- 2015-03-23 IL IL237899A patent/IL237899A/en active IP Right Grant
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2016
- 2016-09-19 US US15/269,163 patent/US9796731B2/en active Active
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2017
- 2017-08-14 IL IL253988A patent/IL253988B/en active IP Right Grant
- 2017-09-19 US US15/708,346 patent/US10100062B2/en active Active
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2018
- 2018-02-27 AU AU2018201392A patent/AU2018201392B2/en active Active
- 2018-02-27 JP JP2018032684A patent/JP2018109044A/ja not_active Ceased
- 2018-09-12 US US16/129,268 patent/US10461449B2/en active Active
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2019
- 2019-03-13 CY CY20191100302T patent/CY1121415T1/el unknown
- 2019-09-18 US US16/574,718 patent/US10944190B2/en active Active
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2020
- 2020-04-06 JP JP2020068137A patent/JP6735000B1/ja active Active
- 2020-06-10 AU AU2020203823A patent/AU2020203823B2/en active Active
- 2020-07-10 JP JP2020118929A patent/JP2020180150A/ja active Pending
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2021
- 2021-06-29 HR HRP20211030TT patent/HRP20211030T1/hr unknown
- 2021-07-02 CY CY20211100594T patent/CY1124337T1/el unknown
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2022
- 2022-02-28 JP JP2022029253A patent/JP2022068367A/ja active Pending
- 2022-03-07 AU AU2022201557A patent/AU2022201557A1/en not_active Abandoned
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2023
- 2023-09-05 US US18/242,321 patent/US20240145953A1/en not_active Abandoned
- 2023-10-23 JP JP2023181529A patent/JP2024010055A/ja active Pending
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2024
- 2024-01-19 US US18/417,406 patent/US20240313444A1/en not_active Abandoned
- 2024-05-31 US US18/679,863 patent/US20250007192A1/en active Pending
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2025
- 2025-03-31 JP JP2025058629A patent/JP2025098242A/ja active Pending