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RU2018145985A - Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений - Google Patents

Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений Download PDF

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Publication number
RU2018145985A
RU2018145985A RU2018145985A RU2018145985A RU2018145985A RU 2018145985 A RU2018145985 A RU 2018145985A RU 2018145985 A RU2018145985 A RU 2018145985A RU 2018145985 A RU2018145985 A RU 2018145985A RU 2018145985 A RU2018145985 A RU 2018145985A
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disorders
treatment
activin
application
bone tissue
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RU2018145985A
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Inventor
Виктор Шорр СЛОАН
Кейт ХРУСКА
Ифу ФАН
Виктория СУНГ
Рэндалл СТИВЕНС
Уилльям СМИТ
Original Assignee
Селджин Корпорейшн
Вашингтон Юниверсити
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Publication of RU2018145985A publication Critical patent/RU2018145985A/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Claims (1)

  1. Способ лечения адинамического нарушения костной ткани у индивидуума, где способ включает введение терапевтически эффективного количества ингибитора ActRII индивидууму, нуждающемуся в лечении адинамического нарушения костной ткани.
RU2018145985A 2012-11-02 2013-11-01 Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений RU2018145985A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261721898P 2012-11-02 2012-11-02
US61/721,898 2012-11-02
US201261740665P 2012-12-21 2012-12-21
US61/740,665 2012-12-21

Related Parent Applications (1)

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RU2015120804A Division RU2678117C2 (ru) 2012-11-02 2013-11-01 Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений

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RU2018145985A true RU2018145985A (ru) 2019-02-18

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RU2015120804A RU2678117C2 (ru) 2012-11-02 2013-11-01 Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений
RU2018145985A RU2018145985A (ru) 2012-11-02 2013-11-01 Антагонисты активина-actrii и их применение для лечения нарушений костной ткани и других нарушений

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US (3) US10195249B2 (ru)
EP (3) EP2914277B1 (ru)
JP (4) JP2016504275A (ru)
KR (3) KR102279522B1 (ru)
CN (1) CN104936605A (ru)
AU (3) AU2013337677B2 (ru)
BR (1) BR112015009948B1 (ru)
CA (2) CA2890217C (ru)
ES (2) ES2652437T3 (ru)
IL (2) IL238443B (ru)
MX (2) MX389254B (ru)
NZ (1) NZ707477A (ru)
RU (2) RU2678117C2 (ru)
WO (1) WO2014071158A1 (ru)
ZA (1) ZA201503135B (ru)

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ES2652437T3 (es) 2018-02-02
IL238443B (en) 2019-07-31
ZA201503135B (en) 2019-09-25
IL267066B (en) 2022-02-01
KR102279522B1 (ko) 2021-07-19
BR112015009948A8 (pt) 2021-10-19
MX2015005538A (es) 2016-02-05
CN104936605A (zh) 2015-09-23
RU2678117C2 (ru) 2019-01-23
JP2020143164A (ja) 2020-09-10
MX366336B (es) 2019-07-05
AU2020213397A1 (en) 2020-08-27
BR112015009948B1 (pt) 2022-12-06
IL238443A0 (en) 2015-06-30
KR20150082423A (ko) 2015-07-15
MX389254B (es) 2025-03-20
JP2016504275A (ja) 2016-02-12
CA2890217A1 (en) 2014-05-08
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US20150283209A1 (en) 2015-10-08
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JP2018168176A (ja) 2018-11-01
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EP3308796A1 (en) 2018-04-18
US20190262423A1 (en) 2019-08-29
KR20210091358A (ko) 2021-07-21
RU2015120804A (ru) 2016-12-27
WO2014071158A1 (en) 2014-05-08
JP2023011741A (ja) 2023-01-24
EP2914277A4 (en) 2016-05-25
BR112015009948A2 (pt) 2017-07-11
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US10195249B2 (en) 2019-02-05

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