RU2016115481A - Композиция галобетазола для местного спрея - Google Patents
Композиция галобетазола для местного спрея Download PDFInfo
- Publication number
- RU2016115481A RU2016115481A RU2016115481A RU2016115481A RU2016115481A RU 2016115481 A RU2016115481 A RU 2016115481A RU 2016115481 A RU2016115481 A RU 2016115481A RU 2016115481 A RU2016115481 A RU 2016115481A RU 2016115481 A RU2016115481 A RU 2016115481A
- Authority
- RU
- Russia
- Prior art keywords
- glycol ether
- glycol
- composition
- ether
- local spray
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims 15
- 239000007921 spray Substances 0.000 title claims 10
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims 43
- 239000003125 aqueous solvent Substances 0.000 claims 6
- 235000014113 dietary fatty acids Nutrition 0.000 claims 5
- 239000003974 emollient agent Substances 0.000 claims 5
- 229930195729 fatty acid Natural products 0.000 claims 5
- 239000000194 fatty acid Substances 0.000 claims 5
- 239000003380 propellant Substances 0.000 claims 5
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 claims 4
- 150000004665 fatty acids Chemical class 0.000 claims 4
- 229940115747 halobetasol Drugs 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- LEHFPXVYPMWYQD-XHIJKXOTSA-N ulobetasol Chemical group C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]2(C)C[C@@H]1O LEHFPXVYPMWYQD-XHIJKXOTSA-N 0.000 claims 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims 3
- 201000004624 Dermatitis Diseases 0.000 claims 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 claims 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 claims 2
- -1 fatty acid esters Chemical class 0.000 claims 2
- 239000007789 gas Substances 0.000 claims 2
- NNPPMTNAJDCUHE-UHFFFAOYSA-N isobutane Chemical compound CC(C)C NNPPMTNAJDCUHE-UHFFFAOYSA-N 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 150000005846 sugar alcohols Polymers 0.000 claims 2
- 150000003626 triacylglycerols Chemical class 0.000 claims 2
- YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 claims 1
- LVGUZGTVOIAKKC-UHFFFAOYSA-N 1,1,1,2-tetrafluoroethane Chemical compound FCC(F)(F)F LVGUZGTVOIAKKC-UHFFFAOYSA-N 0.000 claims 1
- NSGXIBWMJZWTPY-UHFFFAOYSA-N 1,1,1,3,3,3-hexafluoropropane Chemical compound FC(F)(F)CC(F)(F)F NSGXIBWMJZWTPY-UHFFFAOYSA-N 0.000 claims 1
- NPNPZTNLOVBDOC-UHFFFAOYSA-N 1,1-difluoroethane Chemical compound CC(F)F NPNPZTNLOVBDOC-UHFFFAOYSA-N 0.000 claims 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- LVZWSLJZHVFIQJ-UHFFFAOYSA-N Cyclopropane Chemical compound C1CC1 LVZWSLJZHVFIQJ-UHFFFAOYSA-N 0.000 claims 1
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims 1
- 239000004166 Lanolin Substances 0.000 claims 1
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims 1
- 239000002202 Polyethylene glycol Substances 0.000 claims 1
- 208000003251 Pruritus Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 241001303601 Rosacea Species 0.000 claims 1
- 206010039792 Seborrhoea Diseases 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- UWHCKJMYHZGTIT-UHFFFAOYSA-N Tetraethylene glycol, Natural products OCCOCCOCCOCCO UWHCKJMYHZGTIT-UHFFFAOYSA-N 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 239000001273 butane Substances 0.000 claims 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940086555 cyclomethicone Drugs 0.000 claims 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 claims 1
- 239000003623 enhancer Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 235000019441 ethanol Nutrition 0.000 claims 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 claims 1
- ACCCMOQWYVYDOT-UHFFFAOYSA-N hexane-1,1-diol Chemical compound CCCCCC(O)O ACCCMOQWYVYDOT-UHFFFAOYSA-N 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 239000001282 iso-butane Substances 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 229940039717 lanolin Drugs 0.000 claims 1
- 235000019388 lanolin Nutrition 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 claims 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- 230000035515 penetration Effects 0.000 claims 1
- UWJJYHHHVWZFEP-UHFFFAOYSA-N pentane-1,1-diol Chemical compound CCCCC(O)O UWJJYHHHVWZFEP-UHFFFAOYSA-N 0.000 claims 1
- 239000004014 plasticizer Substances 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 239000001294 propane Substances 0.000 claims 1
- 201000004700 rosacea Diseases 0.000 claims 1
- 208000008742 seborrheic dermatitis Diseases 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- ZIBGPFATKBEMQZ-UHFFFAOYSA-N triethylene glycol Chemical compound OCCOCCOCCO ZIBGPFATKBEMQZ-UHFFFAOYSA-N 0.000 claims 1
- 239000001993 wax Substances 0.000 claims 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Claims (14)
1. Композиция галобетазола для местного спрея, содержащая галобетазол, мягчитель, неводный растворитель и пропеллент.
2. Композиция местного спрея по п. 1, где мягчитель выбран из группы, состоящей из триглицеридов жирных кислот, сложных эфиров жирных кислот, многоатомных спиртов, жирных кислот, масел, циклометикона, гидрогенизированного ланолина, восков, лецитина или их смесей.
3. Композиция местного спрея по п. 2, где мягчитель выбран из группы, состоящей из триглицеридов жирных кислот, сложных эфиров жирных кислот и многоатомных спиртов.
4. Композиция местного спрея по п. 1, где неводный растворитель выбран из группы, состоящей из этилового спирта, изопропилового спирта, пропиленгликоля, бутандиола, пентандиола, гександиола, триэтиленгликоля, тетраэтиленгликоля, дипропиленгликоля, дибутиленгликоля, глицерина, диметилизосорбида, простого эфира тетрагидрофурфурилового спирта и полиэтиленгликоля, N-метил-2-пирролидона, 1-метил-2-пирролидинона, диметилсульфоксида, диметилацетамида, молочной кислоты, гликолевой кислоты, метиленхлорида, метил-этил-кетона, этилацетата, метилендиметилового эфира и их смесей.
5. Композиция местного спрея по п. 1, где пропеллент выбран из группы, состоящей из пропана, бутана, изобутана, циклопропана, 1,1,1,2-тетрафторэтана, 1,1,1,2,3,3,3-гептафторпропана, 1,1-дифторэтана, 1,1,1,3,3,3-гексафторпропана, фторуглеродных газов, сжиженного попутного газа и их смесей.
6. Композиция местного спрея по п. 1, где композиция дополнительно содержит солюбилизаторы, усилители проникновения, пленкообразователи, пластификаторы, антиоксиданты, агенты, корректирующие рН, или их смеси.
7. Дозирующая система для введения композиции галобетазола в виде местного спрея, содержащей галобетазол, мягчитель, неводный растворитель и пропеллент, где дозирующая система содержит контейнер и клапанный блок.
8. Способ получения композиции галобетазола для местного спрея, где данный способ включает следующие стадии:
(а) растворение галобетазола в одной части неводного растворителя;
(б) смешивание мягчителя и другой части неводного растворителя в растворе стадии (а);
(в) дозирование раствора стадии (б) в дозирующей системе; и
(г) загрузка пропеллента в дозирующей системе стадии (в).
9. Способ лечения местного состояния кожи путем введения композиции галобетазола в виде местного спрея, содержащей галобетазол, мягчитель, неводный растворитель и пропеллент.
10. Способ по п. 9, где состояние выбрано из группы, состоящей из дерматозов, псориаза, экземы, розовых угрей, обыкновенных угрей, дерматита, зуда, себореи, раковых заболеваний кожи, воспаления и их комбинаций.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2839DE2013 | 2013-09-25 | ||
| IN2839/DEL/2013 | 2013-09-25 | ||
| PCT/IB2014/064745 WO2015044857A1 (en) | 2013-09-25 | 2014-09-22 | Topical spray composition of halobetasol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2016115481A true RU2016115481A (ru) | 2017-10-30 |
| RU2016115481A3 RU2016115481A3 (ru) | 2018-06-29 |
Family
ID=51626113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016115481A RU2016115481A (ru) | 2013-09-25 | 2014-09-22 | Композиция галобетазола для местного спрея |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20160256474A1 (ru) |
| EP (1) | EP3049063A1 (ru) |
| AU (1) | AU2014326199A1 (ru) |
| BR (2) | BR112016006830A2 (ru) |
| CA (1) | CA2925676A1 (ru) |
| MX (1) | MX2016003951A (ru) |
| RU (1) | RU2016115481A (ru) |
| WO (1) | WO2015044857A1 (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE050603T2 (hu) | 2015-06-18 | 2020-12-28 | Bausch Health Ireland Ltd | Egy kortikoszteroidot és egy retinoidot tartalmazó topikális készítmények psoriasis kezelésére |
| EA035300B1 (ru) | 2015-12-15 | 2020-05-26 | Терапьютикс Инк. | Вспениваемая композиция галобетазола (варианты) и способ лечения |
| MY188053A (en) | 2015-12-15 | 2021-11-15 | Therapeutics Inc | Corticosteroid containing foam compositions and method of manufacture thereof |
| US20170340649A1 (en) | 2016-05-30 | 2017-11-30 | Sun Pharmaceutical Industries Limited | Topical aqueous spray compositions of halobetasol |
| US20180028767A1 (en) * | 2016-07-27 | 2018-02-01 | Sun Pharmaceutical Industries Limited | Topical spray system of halobetasol |
| CA3040867C (en) * | 2016-10-21 | 2024-03-12 | Crescita Therapeutics Inc. | Halobetasol propionate compositions |
| US11311482B2 (en) | 2017-05-12 | 2022-04-26 | Bausch Health Us, Llc | Topical compositions and methods for treating skin diseases |
| WO2019224035A1 (en) | 2018-05-24 | 2019-11-28 | Almirall, S.A. | Topical pharmaceutical compositions comprising a corticosteroid |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9504265D0 (en) | 1995-03-03 | 1995-04-19 | Medeva Plc | Corticosteroid-containing pharmaceutical composition |
| US6248763B1 (en) * | 1998-05-19 | 2001-06-19 | Scivoletto Rosemarie | Composition for treating skin conditions |
| US6479058B1 (en) * | 1999-09-02 | 2002-11-12 | Mccadden Michael E. | Composition for the topical treatment of poison ivy and other forms of contact dermatitis |
| US20080107758A1 (en) | 2001-06-15 | 2008-05-08 | Cuticeuticals, Inc. | Topical steroid spray with botanic seed oils |
| US6579512B2 (en) * | 2001-06-15 | 2003-06-17 | Crutchfield, Iii Charles E. | Topical steroid spray |
| JP2008540508A (ja) | 2005-05-09 | 2008-11-20 | フォーミックス エルティーディー． | 起泡性ビヒクル及びその医薬組成物 |
| EP1888026A4 (en) * | 2005-05-27 | 2012-07-04 | Taro Pharmaceuticals North America Inc | STABLE LIQUID FORMULATION WITH DESOXIMETASON AND ISOPROPYLMYRISTATE WITH REDUCED OXIDIZED CONTAMINATION DURING LONG-TERM STORAGE |
| US20080260655A1 (en) * | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| US20080206155A1 (en) | 2006-11-14 | 2008-08-28 | Foamix Ltd. | Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses |
| US20090136430A1 (en) * | 2007-11-27 | 2009-05-28 | Dugger Harry A | Antihistamine/Corticosteroid preparations for the treatment of atopic dermatitis |
-
2014
- 2014-09-22 CA CA2925676A patent/CA2925676A1/en not_active Abandoned
- 2014-09-22 WO PCT/IB2014/064745 patent/WO2015044857A1/en not_active Ceased
- 2014-09-22 RU RU2016115481A patent/RU2016115481A/ru not_active Application Discontinuation
- 2014-09-22 AU AU2014326199A patent/AU2014326199A1/en not_active Abandoned
- 2014-09-22 US US15/024,977 patent/US20160256474A1/en not_active Abandoned
- 2014-09-22 MX MX2016003951A patent/MX2016003951A/es unknown
- 2014-09-22 BR BR112016006830A patent/BR112016006830A2/pt not_active IP Right Cessation
- 2014-09-22 EP EP14776741.2A patent/EP3049063A1/en not_active Withdrawn
-
2017
- 2017-06-09 BR BR132017012408-7A patent/BR132017012408E2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP3049063A1 (en) | 2016-08-03 |
| BR132017012408E2 (pt) | 2019-05-14 |
| CA2925676A1 (en) | 2015-04-02 |
| WO2015044857A1 (en) | 2015-04-02 |
| AU2014326199A1 (en) | 2016-04-28 |
| BR112016006830A2 (pt) | 2017-08-01 |
| RU2016115481A3 (ru) | 2018-06-29 |
| MX2016003951A (es) | 2016-07-06 |
| US20160256474A1 (en) | 2016-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20181022 |