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RU2012123372A - Гетероциклические модуляторы транспортеров атф-связывающей кассеты - Google Patents

Гетероциклические модуляторы транспортеров атф-связывающей кассеты Download PDF

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Publication number
RU2012123372A
RU2012123372A RU2012123372/04A RU2012123372A RU2012123372A RU 2012123372 A RU2012123372 A RU 2012123372A RU 2012123372/04 A RU2012123372/04 A RU 2012123372/04A RU 2012123372 A RU2012123372 A RU 2012123372A RU 2012123372 A RU2012123372 A RU 2012123372A
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RU
Russia
Prior art keywords
atp
binding cassette
cassette transporters
heterocyclic modulators
patient
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RU2012123372/04A
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English (en)
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RU2608610C2 (ru
Inventor
РУА Сара АДИДА
Мэттью ХЭМИЛТОН
Марк Миллер
Петер Д.Й. ГРОТЕНХЕЙС
Брайан БЕАР
Джейсон МАККАРТИ
Цзинлань ЧЖОУ
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Вертекс Фармасьютикалз Инкорпорейтед
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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    • C07—ORGANIC CHEMISTRY
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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Abstract

Способ лечения или ослабления тяжести муковисцидоза у пациента, включающий стадию введения вышеуказанному пациенту эффективного количества соединения формулыили его фармацевтически приемлемой соли или композиции.

Claims (1)

  1. Способ лечения или ослабления тяжести муковисцидоза у пациента, включающий стадию введения вышеуказанному пациенту эффективного количества соединения формулы
    Figure 00000001
    или его фармацевтически приемлемой соли или композиции.
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