RU2011114965A - PHARMACEUTICAL COMPOSITION CONTAINING INSULIN AND LIPOSOMES FOR LOCAL APPLICATION AS A BIOFILM - Google Patents
PHARMACEUTICAL COMPOSITION CONTAINING INSULIN AND LIPOSOMES FOR LOCAL APPLICATION AS A BIOFILM Download PDFInfo
- Publication number
- RU2011114965A RU2011114965A RU2011114965/15A RU2011114965A RU2011114965A RU 2011114965 A RU2011114965 A RU 2011114965A RU 2011114965/15 A RU2011114965/15 A RU 2011114965/15A RU 2011114965 A RU2011114965 A RU 2011114965A RU 2011114965 A RU2011114965 A RU 2011114965A
- Authority
- RU
- Russia
- Prior art keywords
- pharmaceutical composition
- liposomes
- biofilm
- composition containing
- local application
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title claims abstract 10
- 102000004877 Insulin Human genes 0.000 title claims abstract 5
- 108090001061 Insulin Proteins 0.000 title claims abstract 5
- 229940125396 insulin Drugs 0.000 title claims abstract 5
- 239000002502 liposome Substances 0.000 title claims abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract 5
- 229920002401 polyacrylamide Polymers 0.000 claims abstract 4
- 239000003937 drug carrier Substances 0.000 claims abstract 2
- 239000000203 mixture Substances 0.000 claims abstract 2
- 239000000546 pharmaceutical excipient Substances 0.000 claims abstract 2
- 239000003755 preservative agent Substances 0.000 claims abstract 2
- 230000002335 preservative effect Effects 0.000 claims abstract 2
- 239000012049 topical pharmaceutical composition Substances 0.000 claims abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract 2
Landscapes
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
1. Фармацевтическая композиция для местного применения, содержащая инсулин и фармацевтически приемлемые носители или эксципиенты, отличающаяся тем, что она дополнительно включает в себя липосомы. ! 2. Фармацевтическая композиция по п.1, отличающаяся тем, что она дополнительно включает полиакриламид и представлена в виде биопленки. ! 3. Фармацевтическая композиция по п.2, отличающаяся тем, что она имеет следующий состав, мас.%: ! инсулин 0,004-0,04 липосомы 0,01-20,0 полиакриламид 0,5-10,0 консервант 0,05-1,0 вода деминерализованная 68,96-99,436 1. A topical pharmaceutical composition comprising insulin and pharmaceutically acceptable carriers or excipients, characterized in that it further includes liposomes. ! 2. The pharmaceutical composition according to claim 1, characterized in that it further comprises polyacrylamide and is presented in the form of a biofilm. ! 3. The pharmaceutical composition according to claim 2, characterized in that it has the following composition, wt.%:! insulin 0.004-0.04 liposomes 0.01-20.0 polyacrylamide 0.5-10.0 preservative 0.05-1.0 demineralized water 68.96-99.436
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2011114965/15A RU2483749C2 (en) | 2011-04-15 | 2011-04-15 | Pharmaceutical composition containing insulin and liposomes for topical application in form of biofilm |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2011114965/15A RU2483749C2 (en) | 2011-04-15 | 2011-04-15 | Pharmaceutical composition containing insulin and liposomes for topical application in form of biofilm |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2011114965A true RU2011114965A (en) | 2012-10-20 |
| RU2483749C2 RU2483749C2 (en) | 2013-06-10 |
Family
ID=47145114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011114965/15A RU2483749C2 (en) | 2011-04-15 | 2011-04-15 | Pharmaceutical composition containing insulin and liposomes for topical application in form of biofilm |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2483749C2 (en) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9602280D0 (en) * | 1996-06-10 | 1996-06-10 | Pharmatrix Ab | Immune-stimulating lipid formulation |
| PT990440E (en) * | 1997-02-27 | 2009-02-05 | Novartis Ag | Pharmaceutical composition comprising 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol, a lecithin and a saccharide |
| DK1423102T3 (en) * | 2001-09-04 | 2008-04-14 | Trommsdorff Arzneimittel | Patches for the treatment of nail growth dysfunctions and disorders |
| CA2501601C (en) * | 2002-10-25 | 2008-12-30 | Seymour J. Kurtz | Method of treating insulin resistance, adult onset diabetes and metabolic syndrome x using small unilamellar vesicles |
| JP2006514990A (en) * | 2002-12-27 | 2006-05-18 | ディオベックス， インコーポレイテッド | Compositions and methods for prevention and control of insulin-induced hypoglycemia |
| CN101180073A (en) * | 2005-04-27 | 2008-05-14 | 贾拉尔·梅萨德克 | insulin combination |
| JP2010187707A (en) * | 2007-06-12 | 2010-09-02 | Hokkaido Univ | Liposome preparation for iontophoresis comprising insulin encapsulated therein |
| RU2373950C1 (en) * | 2008-05-05 | 2009-11-27 | Владимир Сергеевич Кубышкин | Pharmaceutical composition for prevention and/or treatment of cold-related diseases and herpes simplex, and method for making thereof |
-
2011
- 2011-04-15 RU RU2011114965/15A patent/RU2483749C2/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2483749C2 (en) | 2013-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20170416 |