RU2008106612A - Стимулирующие рост полипептиды для использования у рыб и ракообразных - Google Patents
Стимулирующие рост полипептиды для использования у рыб и ракообразных Download PDFInfo
- Publication number
- RU2008106612A RU2008106612A RU2008106612/13A RU2008106612A RU2008106612A RU 2008106612 A RU2008106612 A RU 2008106612A RU 2008106612/13 A RU2008106612/13 A RU 2008106612/13A RU 2008106612 A RU2008106612 A RU 2008106612A RU 2008106612 A RU2008106612 A RU 2008106612A
- Authority
- RU
- Russia
- Prior art keywords
- polypeptides
- fish
- crustaceans
- growth
- polypeptide
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title claims abstract 15
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract 15
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract 15
- 239000013078 crystal Substances 0.000 title 1
- 241000251468 Actinopterygii Species 0.000 claims abstract 6
- 241000238424 Crustacea Species 0.000 claims abstract 5
- 241000235058 Komagataella pastoris Species 0.000 claims abstract 4
- 239000012228 culture supernatant Substances 0.000 claims abstract 3
- 230000000694 effects Effects 0.000 claims abstract 3
- 238000007654 immersion Methods 0.000 claims abstract 2
- 230000004083 survival effect Effects 0.000 claims abstract 2
- 230000004936 stimulating effect Effects 0.000 claims 2
- 208000035240 Disease Resistance Diseases 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 210000005007 innate immune system Anatomy 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 241000276707 Tilapia Species 0.000 abstract 1
- 239000003674 animal food additive Substances 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 210000000987 immune system Anatomy 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Polymers & Plastics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Animal Husbandry (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Obesity (AREA)
- Insects & Arthropods (AREA)
- Marine Sciences & Fisheries (AREA)
Abstract
1. Полипептид, характеризующийся своей полипептидной цепью, состоящей из последовательности аминокислот, содержащейся в последовательностях SEQ ID NO.7 или SEQ ID NO.8. ! 2. Полипептид по п.1 характеризуется тем, что он получен с помощью Pichia pastoris. ! 3. Композиция, которая включает любой из полипептидов, определенных в п.1 для стимуляции роста рыб и ракообразных. ! 4. Применение супернатантов культуры Pichia pastoris, содержащих полипептиды, определенные в п.1, в составе корма для стимуляции роста и/или устойчивости к заболеваниям у рыб и ракообразных в дозе, эквивалентной эффекту 4,8 мг полипептида/кг корма. ! 5. Применение супернатантов культуры Pichia pastoris, содержащих полипептиды, определенные в п.1 в концентрации от 0,05 до 0,5 мг полипептида/литр воды, для иммерсионного воздействия на рыб и ракообразных для стимуляции роста, выживаемости и качества личинок. ! 6. Композиция, включающая любой из полипептидов по п.1 для стимуляции гуморальной врожденной иммунной системы рыб и ракообразных. ! 7. Композиция, которая включает любой из полипептидов, определенных в п.1 для обработки декоративных рыб.
Claims (7)
1. Полипептид, характеризующийся своей полипептидной цепью, состоящей из последовательности аминокислот, содержащейся в последовательностях SEQ ID NO.7 или SEQ ID NO.8.
2. Полипептид по п.1 характеризуется тем, что он получен с помощью Pichia pastoris.
3. Композиция, которая включает любой из полипептидов, определенных в п.1 для стимуляции роста рыб и ракообразных.
4. Применение супернатантов культуры Pichia pastoris, содержащих полипептиды, определенные в п.1, в составе корма для стимуляции роста и/или устойчивости к заболеваниям у рыб и ракообразных в дозе, эквивалентной эффекту 4,8 мг полипептида/кг корма.
5. Применение супернатантов культуры Pichia pastoris, содержащих полипептиды, определенные в п.1 в концентрации от 0,05 до 0,5 мг полипептида/литр воды, для иммерсионного воздействия на рыб и ракообразных для стимуляции роста, выживаемости и качества личинок.
6. Композиция, включающая любой из полипептидов по п.1 для стимуляции гуморальной врожденной иммунной системы рыб и ракообразных.
7. Композиция, которая включает любой из полипептидов, определенных в п.1 для обработки декоративных рыб.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU2005-0135 | 2005-07-21 | ||
| CU20050135A CU23577A1 (es) | 2005-07-21 | 2005-07-21 | Polipéptidos estimuladores del crecimiento para uso en peces y crustáceos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2008106612A true RU2008106612A (ru) | 2009-08-27 |
Family
ID=36956134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008106612/13A RU2008106612A (ru) | 2005-07-21 | 2006-06-23 | Стимулирующие рост полипептиды для использования у рыб и ракообразных |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7919463B2 (ru) |
| EP (1) | EP1911764B1 (ru) |
| JP (1) | JP4939536B2 (ru) |
| KR (1) | KR101190022B1 (ru) |
| CN (1) | CN101253194B (ru) |
| AT (1) | ATE439374T1 (ru) |
| AU (1) | AU2006272216B2 (ru) |
| BR (1) | BRPI0613621A2 (ru) |
| CA (1) | CA2615833C (ru) |
| CU (1) | CU23577A1 (ru) |
| DE (1) | DE602006008478D1 (ru) |
| ES (1) | ES2331627T3 (ru) |
| IL (1) | IL188864A0 (ru) |
| MX (1) | MX2008000962A (ru) |
| MY (1) | MY145699A (ru) |
| RU (1) | RU2008106612A (ru) |
| WO (1) | WO2007009403A1 (ru) |
| ZA (1) | ZA200800924B (ru) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102703483B (zh) * | 2012-06-08 | 2014-10-01 | 湖北肽洋红生物工程有限公司 | 罗非鱼重组口服蛋白tat-gh及制备方法和应用 |
| CN105764520B (zh) * | 2013-11-28 | 2020-03-03 | 株式会社钟化 | 甲壳类的传染病的抑制方法 |
| HK1218486A2 (zh) * | 2015-12-09 | 2017-02-17 | Wan Keung Raymond Wong | 提高鱼生长的手段和方法 |
| CN107242161A (zh) * | 2017-06-05 | 2017-10-13 | 舟山市普陀兴海养殖优质种苗选育研究所 | 一种黑鲷鱼苗种培育技术 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0387457A1 (en) * | 1989-01-06 | 1990-09-19 | Eurogentec S.A. | Recombinant fish hormone proteins |
| JPH05184352A (ja) | 1990-01-16 | 1993-07-27 | Centro De Ing Genetica Y Biotecnol | ピヒア パストリス（Ｐｉｃｈｉａ ｐａｓｔｏｒｉｓ）酵母中での異種遺伝子の発現方法、発現ベクターおよび形質転換微生物 |
| US5695954A (en) | 1993-05-14 | 1997-12-09 | University Of Victoria Innovation & Development Corporation | DNA encoding two fish neuropeptides |
| JP3706634B2 (ja) | 1997-03-24 | 2005-10-12 | エイチ・アイ・エイチ・バイオセンター株式会社 | 新規な合成ポリペプチド |
| US6429305B1 (en) * | 2000-04-14 | 2002-08-06 | Academia Sinica | Fish growth hormones |
| EP1447181A1 (en) | 2003-02-11 | 2004-08-18 | Alto Danmark A/S | Lateral handgrip |
-
2005
- 2005-07-21 CU CU20050135A patent/CU23577A1/es not_active IP Right Cessation
-
2006
- 2006-06-23 ES ES06753160T patent/ES2331627T3/es active Active
- 2006-06-23 JP JP2008521780A patent/JP4939536B2/ja not_active Expired - Fee Related
- 2006-06-23 KR KR1020087004003A patent/KR101190022B1/ko not_active Expired - Fee Related
- 2006-06-23 MX MX2008000962A patent/MX2008000962A/es active IP Right Grant
- 2006-06-23 CA CA2615833A patent/CA2615833C/en not_active Expired - Fee Related
- 2006-06-23 US US11/989,088 patent/US7919463B2/en not_active Expired - Fee Related
- 2006-06-23 BR BRPI0613621-4A patent/BRPI0613621A2/pt not_active IP Right Cessation
- 2006-06-23 EP EP06753160A patent/EP1911764B1/en active Active
- 2006-06-23 AT AT06753160T patent/ATE439374T1/de not_active IP Right Cessation
- 2006-06-23 DE DE602006008478T patent/DE602006008478D1/de active Active
- 2006-06-23 RU RU2008106612/13A patent/RU2008106612A/ru unknown
- 2006-06-23 CN CN2006800313781A patent/CN101253194B/zh not_active Expired - Fee Related
- 2006-06-23 AU AU2006272216A patent/AU2006272216B2/en not_active Ceased
- 2006-06-23 WO PCT/CU2006/000006 patent/WO2007009403A1/es not_active Ceased
- 2006-07-04 MY MYPI20063173A patent/MY145699A/en unknown
-
2008
- 2008-01-17 IL IL188864A patent/IL188864A0/en unknown
- 2008-01-29 ZA ZA200800924A patent/ZA200800924B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602006008478D1 (de) | 2009-09-24 |
| US7919463B2 (en) | 2011-04-05 |
| EP1911764B1 (en) | 2009-08-12 |
| CN101253194A (zh) | 2008-08-27 |
| WO2007009403A1 (es) | 2007-01-25 |
| CA2615833C (en) | 2012-02-21 |
| ES2331627T3 (es) | 2010-01-11 |
| CU23577A1 (es) | 2010-09-30 |
| KR101190022B1 (ko) | 2012-10-12 |
| JP2009501735A (ja) | 2009-01-22 |
| CA2615833A1 (en) | 2007-01-25 |
| ZA200800924B (en) | 2008-11-26 |
| JP4939536B2 (ja) | 2012-05-30 |
| KR20080041656A (ko) | 2008-05-13 |
| MX2008000962A (es) | 2008-03-27 |
| EP1911764A1 (en) | 2008-04-16 |
| CN101253194B (zh) | 2011-09-28 |
| AU2006272216B2 (en) | 2010-09-16 |
| BRPI0613621A2 (pt) | 2012-11-06 |
| ATE439374T1 (de) | 2009-08-15 |
| IL188864A0 (en) | 2008-04-13 |
| AU2006272216A1 (en) | 2007-01-25 |
| US20100167998A1 (en) | 2010-07-01 |
| MY145699A (en) | 2012-03-30 |
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