RU2007125570A - Лекарственное средство для гигиеничного применения на ушах - Google Patents
Лекарственное средство для гигиеничного применения на ушах Download PDFInfo
- Publication number
- RU2007125570A RU2007125570A RU2007125570/15A RU2007125570A RU2007125570A RU 2007125570 A RU2007125570 A RU 2007125570A RU 2007125570/15 A RU2007125570/15 A RU 2007125570/15A RU 2007125570 A RU2007125570 A RU 2007125570A RU 2007125570 A RU2007125570 A RU 2007125570A
- Authority
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- Russia
- Prior art keywords
- drug according
- dosage form
- acid
- corticoid
- drug
- Prior art date
Links
- 210000005069 ears Anatomy 0.000 title claims 2
- 239000003814 drug Substances 0.000 claims 20
- 229940079593 drug Drugs 0.000 claims 17
- 239000002552 dosage form Substances 0.000 claims 7
- 239000003470 adrenal cortex hormone Substances 0.000 claims 5
- RKHQGWMMUURILY-UHRZLXHJSA-N cortivazol Chemical compound C([C@H]1[C@@H]2C[C@H]([C@]([C@@]2(C)C[C@H](O)[C@@H]1[C@@]1(C)C2)(O)C(=O)COC(C)=O)C)=C(C)C1=CC1=C2C=NN1C1=CC=CC=C1 RKHQGWMMUURILY-UHRZLXHJSA-N 0.000 claims 5
- 239000007788 liquid Substances 0.000 claims 5
- 239000002253 acid Substances 0.000 claims 4
- 230000002924 anti-infective effect Effects 0.000 claims 4
- 229940124307 fluoroquinolone Drugs 0.000 claims 4
- 239000003429 antifungal agent Substances 0.000 claims 3
- 238000009516 primary packaging Methods 0.000 claims 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 2
- 239000012678 infectious agent Substances 0.000 claims 2
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 claims 2
- OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 claims 1
- SPFYMRJSYKOXGV-UHFFFAOYSA-N Baytril Chemical compound C1CN(CC)CCN1C(C(=C1)F)=CC2=C1C(=O)C(C(O)=O)=CN2C1CC1 SPFYMRJSYKOXGV-UHFFFAOYSA-N 0.000 claims 1
- BPFYOAJNDMUVBL-UHFFFAOYSA-N LSM-5799 Chemical compound C1CN(C)CCN1C1=C(F)C=C2C(=O)C(C(O)=O)=CN3N(C)COC1=C32 BPFYOAJNDMUVBL-UHFFFAOYSA-N 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims 1
- 235000021355 Stearic acid Nutrition 0.000 claims 1
- AKUJBENLRBOFTD-HIBZCRSPSA-N [2-[(9r,10s,11s,13s,16r,17r)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)C1C1C[C@@H](C)[C@@](C(=O)COC(C)=O)(O)[C@@]1(C)C[C@@H]2O AKUJBENLRBOFTD-HIBZCRSPSA-N 0.000 claims 1
- 229960002537 betamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-DVTGEIKXSA-N betamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-DVTGEIKXSA-N 0.000 claims 1
- 229960002206 bifonazole Drugs 0.000 claims 1
- 229960004022 clotrimazole Drugs 0.000 claims 1
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 229960000740 enrofloxacin Drugs 0.000 claims 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 claims 1
- 229960002531 marbofloxacin Drugs 0.000 claims 1
- 229940126601 medicinal product Drugs 0.000 claims 1
- 229960002509 miconazole Drugs 0.000 claims 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims 1
- 150000007524 organic acids Chemical class 0.000 claims 1
- 229960001248 pradofloxacin Drugs 0.000 claims 1
- LZLXHGFNOWILIY-APPDUMDISA-N pradofloxacin Chemical compound C12=C(C#N)C(N3C[C@H]4NCCC[C@H]4C3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 LZLXHGFNOWILIY-APPDUMDISA-N 0.000 claims 1
- 235000019260 propionic acid Nutrition 0.000 claims 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims 1
- 229910001961 silver nitrate Inorganic materials 0.000 claims 1
- UEJSSZHHYBHCEL-UHFFFAOYSA-N silver(1+) sulfadiazinate Chemical compound [Ag+].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 UEJSSZHHYBHCEL-UHFFFAOYSA-N 0.000 claims 1
- 235000010199 sorbic acid Nutrition 0.000 claims 1
- 239000004334 sorbic acid Substances 0.000 claims 1
- 229940075582 sorbic acid Drugs 0.000 claims 1
- 239000008117 stearic acid Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 230000009974 thixotropic effect Effects 0.000 claims 1
- 229960005294 triamcinolone Drugs 0.000 claims 1
- GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0046—Ear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Claims (21)
1. Лекарственное средство для лечения заболеваний ушей у человека или у животного, содержащее
(а) антиинфекционное средство,
(б) в жидкой основе,
заполненное в первичную упаковку для введения одной разовой дозы.
2. Лекарственное средство по п.1, содержащее в качестве антиинфекционного средства фторхинолон.
3. Лекарственное средство по п.2, содержащее в качестве фторхинолона энрофлоксацин.
4. Лекарственное средство по п.2, содержащее в качестве фторхинолона прадофлоксацин.
5. Лекарственное средство по п.2, содержащее в качестве фторхинолона марбофлоксацин.
6. Лекарственное средство по п.1, содержащее дополнительно другую субстанцию с антиинфекционной активностью, например коллоидное серебро, нитрат серебра или сульфадиазин-серебро.
7. Лекарственное средство по п.1, содержащее дополнительно антимикотическое средство.
8. Лекарственное средство по п.7, содержащее в качестве антимикотического средства клотримазол, миконазол или бифоназол.
9. Лекарственное средство по п.1, содержащее дополнительно кортикоид.
10. Лекарственное средство по п.9, содержащее в качестве кортикоида дексаметазон, бетаметазон или триамцинолон (или их производные).
11. Лекарственное средство по п.10, содержащее дексаметазон-21-ацетат.
12. Лекарственное средство по одному из пп.1-11, у которого содержимое первичной упаковки имеет тиксотропные свойства.
13. Лекарственное средство по одному из пп.1-11, у которого содержимое первичной упаковки содержит жидкую масляную основу.
14. Лекарственное средство по одному из пп.1-11, у которого содержимое первичной упаковки представляет собой суспензию.
15. Лекарственная форма лекарственного средства, содержащая (i) от 0,001 до 6 мас.% антиинфекционного средства, (ii) от 0,01 до 10 мас.% антимикотического средства, (iii) от 0,001 до 2 мас.% кортикоида, (iv) от 99,9 до 72 мас.% жидкой основы.
16. Лекарственная форма лекарственного средства по п.15, содержащая в качестве кортикоида эфир кортикоида.
17. Лекарственная форма лекарственного средства по п.15, содержащая в качестве жидкой основы жидкую масляную основу.
18. Лекарственная форма лекарственного средства по одному из пп.15-17, содержащая дополнительно кислоту.
19. Лекарственная форма лекарственного средства по п.18, содержащая в качестве кислоты органическую кислоту, в частности сорбиновую кислоту, стеариновую кислоту и пропионовую кислоту.
20. Лекарственная форма лекарственного средства по п.18, содержащая кислоту в количестве до 30 мас.%.
21. Лекарственная форма лекарственного средства по п.18, содержащая кислоту в количестве от 0,05 до 2 мас.%.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004059220.9 | 2004-12-09 | ||
| DE102004059220 | 2004-12-09 | ||
| DE102005055385A DE102005055385A1 (de) | 2004-12-09 | 2005-11-17 | Arzneimittel zur hygienischen Applikation im Ohr |
| DE102005055385.0 | 2005-11-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2007125570A true RU2007125570A (ru) | 2009-01-20 |
| RU2431486C2 RU2431486C2 (ru) | 2011-10-20 |
Family
ID=35735089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2007125570/15A RU2431486C2 (ru) | 2004-12-09 | 2005-12-03 | Лекарственное средство для гигиеничного применения на ушах |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20090011045A1 (ru) |
| EP (1) | EP1830803A2 (ru) |
| JP (1) | JP2008522998A (ru) |
| KR (1) | KR20070086799A (ru) |
| AR (1) | AR052990A1 (ru) |
| AU (1) | AU2005313602A1 (ru) |
| BR (1) | BRPI0518855A2 (ru) |
| CA (1) | CA2594103A1 (ru) |
| CR (1) | CR9142A (ru) |
| DE (1) | DE102005055385A1 (ru) |
| GT (1) | GT200500361A (ru) |
| IL (1) | IL183744A0 (ru) |
| MX (1) | MX2007006689A (ru) |
| NO (1) | NO20073148L (ru) |
| NZ (1) | NZ555640A (ru) |
| PE (1) | PE20061145A1 (ru) |
| RU (1) | RU2431486C2 (ru) |
| TW (1) | TW200637611A (ru) |
| WO (1) | WO2006061156A2 (ru) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006049520A1 (de) | 2006-10-20 | 2008-04-24 | Bayer Healthcare Ag | Verfahren zur Herstellung von Pradofloxacin |
| DE102007055341A1 (de) * | 2007-11-19 | 2009-05-20 | Bayer Animal Health Gmbh | Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren |
| GR20090100230A (el) | 2009-04-14 | 2010-11-18 | Casso Pharmaceuticals Ε.Π.Ε, | Απο του στοματος εναιωρημα οξικης δεξαμεθανοζης-συνθεση καλυψης γευσης της δεξαμεθανοζης |
| WO2013106230A1 (en) * | 2012-01-10 | 2013-07-18 | Entrx LLC | Otic formulations, methods and devices |
| US9849126B2 (en) | 2013-01-03 | 2017-12-26 | Entrx LLC | Sterile otic formulations |
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-
2005
- 2005-11-17 DE DE102005055385A patent/DE102005055385A1/de not_active Withdrawn
- 2005-12-03 CA CA002594103A patent/CA2594103A1/en not_active Abandoned
- 2005-12-03 US US11/721,204 patent/US20090011045A1/en not_active Abandoned
- 2005-12-03 EP EP05816509A patent/EP1830803A2/de not_active Withdrawn
- 2005-12-03 KR KR1020077014903A patent/KR20070086799A/ko not_active Ceased
- 2005-12-03 RU RU2007125570/15A patent/RU2431486C2/ru not_active IP Right Cessation
- 2005-12-03 BR BRPI0518855-5A patent/BRPI0518855A2/pt not_active IP Right Cessation
- 2005-12-03 MX MX2007006689A patent/MX2007006689A/es not_active Application Discontinuation
- 2005-12-03 JP JP2007544787A patent/JP2008522998A/ja active Pending
- 2005-12-03 WO PCT/EP2005/012978 patent/WO2006061156A2/de not_active Ceased
- 2005-12-03 AU AU2005313602A patent/AU2005313602A1/en not_active Abandoned
- 2005-12-03 NZ NZ555640A patent/NZ555640A/en not_active IP Right Cessation
- 2005-12-07 PE PE2005001419A patent/PE20061145A1/es not_active Application Discontinuation
- 2005-12-08 GT GT200500361A patent/GT200500361A/es unknown
- 2005-12-08 TW TW094143288A patent/TW200637611A/zh unknown
- 2005-12-09 AR ARP050105158A patent/AR052990A1/es not_active Application Discontinuation
-
2007
- 2007-05-23 CR CR9142A patent/CR9142A/es unknown
- 2007-06-07 IL IL183744A patent/IL183744A0/en unknown
- 2007-06-20 NO NO20073148A patent/NO20073148L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW200637611A (en) | 2006-11-01 |
| RU2431486C2 (ru) | 2011-10-20 |
| CA2594103A1 (en) | 2006-06-15 |
| NO20073148L (no) | 2007-08-22 |
| NZ555640A (en) | 2009-12-24 |
| MX2007006689A (es) | 2007-08-14 |
| WO2006061156A3 (de) | 2006-08-24 |
| AR052990A1 (es) | 2007-04-18 |
| EP1830803A2 (de) | 2007-09-12 |
| KR20070086799A (ko) | 2007-08-27 |
| WO2006061156A2 (de) | 2006-06-15 |
| IL183744A0 (en) | 2008-04-13 |
| DE102005055385A1 (de) | 2006-06-14 |
| JP2008522998A (ja) | 2008-07-03 |
| PE20061145A1 (es) | 2006-12-29 |
| GT200500361A (es) | 2006-11-07 |
| CR9142A (es) | 2007-12-04 |
| BRPI0518855A2 (pt) | 2008-12-09 |
| AU2005313602A1 (en) | 2006-06-15 |
| US20090011045A1 (en) | 2009-01-08 |
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