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PE20061145A1 - Composicion farmaceutica otica que comprende un antiinfeccioso, un antimicotico y un corticoide - Google Patents

Composicion farmaceutica otica que comprende un antiinfeccioso, un antimicotico y un corticoide

Info

Publication number
PE20061145A1
PE20061145A1 PE2005001419A PE2005001419A PE20061145A1 PE 20061145 A1 PE20061145 A1 PE 20061145A1 PE 2005001419 A PE2005001419 A PE 2005001419A PE 2005001419 A PE2005001419 A PE 2005001419A PE 20061145 A1 PE20061145 A1 PE 20061145A1
Authority
PE
Peru
Prior art keywords
composition
weight
amount
antiinfective
corticoid
Prior art date
Application number
PE2005001419A
Other languages
English (en)
Inventor
Iris Heep
Gert Daube
Dirk Mertin
Ernst Bottcher
Georg Schulte
Ulrike Umgelder
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of PE20061145A1 publication Critical patent/PE20061145A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE A) UN ANTIINFECCIOSO TAL COMO ENROFLOXACINA, PRADOFLOXACINA, MARBOFLOXACINA, ENTRE OTROS, QUE SE ENCUENTRA EN UNA CANTIDAD DE 0,001 A 6% EN PESO DE LA COMPOSICION; B) UN ANTIMICOTICO TAL COMO CLOTRIMAZOL, MICONAZOL, BIFONAZOL, ENTRE OTROS, QUE SE ENCUENTRA EN UNA CANTIDAD DE 0,01 A 10% EN PESO DE LA COMPOSICION; C) UN CORTICOIDE TAL COMO DEXAMETASONA, BETAMETASONA, TRIAMCINOLONA, ENTRE OTROS, QUE SE ENCUENTRA EN UNA CANTIDAD DE 0,001 A 2% EN PESO DE LA COMPOSICION; D) UNA BASE FLUIDA OLEOSA TAL COMO ACEITE DE SOYA, DE GIRASOL, DE OLIVA, ENTRE OTROS, UNA BASE FLUIDA ACUOSA TAL COMO AGUA, GLICERINA, PROPILENGLICOL O POLIETILENGLICOLES O UNA MEZCLA DE ESTOS, QUE SE ENCUENTRA EN UNA CANTIDAD DE 99,9 A 72% EN PESO DE LA COMPOSICION; Y E) UN ACIDO TAL COMO ACIDO SORBICO, ACIDO ESTEARICO O ACIDO PROPIONICO QUE SE ENCUENTRA EN UNA CANTIDAD DE 0,05 A 2% EN PESO DE LA COMPOSICION. DICHA COMPOSICION PRESENTA PROPIEDADES TIXOTROPICAS Y ES UTIL EN EL TRATAMIENTO DE ENFERMEDADES DEL OIDO EN ANIMALES Y SERES HUMANOO
PE2005001419A 2004-12-09 2005-12-07 Composicion farmaceutica otica que comprende un antiinfeccioso, un antimicotico y un corticoide PE20061145A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004059220 2004-12-09
DE102005055385A DE102005055385A1 (de) 2004-12-09 2005-11-17 Arzneimittel zur hygienischen Applikation im Ohr

Publications (1)

Publication Number Publication Date
PE20061145A1 true PE20061145A1 (es) 2006-12-29

Family

ID=35735089

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2005001419A PE20061145A1 (es) 2004-12-09 2005-12-07 Composicion farmaceutica otica que comprende un antiinfeccioso, un antimicotico y un corticoide

Country Status (19)

Country Link
US (1) US20090011045A1 (es)
EP (1) EP1830803A2 (es)
JP (1) JP2008522998A (es)
KR (1) KR20070086799A (es)
AR (1) AR052990A1 (es)
AU (1) AU2005313602A1 (es)
BR (1) BRPI0518855A2 (es)
CA (1) CA2594103A1 (es)
CR (1) CR9142A (es)
DE (1) DE102005055385A1 (es)
GT (1) GT200500361A (es)
IL (1) IL183744A0 (es)
MX (1) MX2007006689A (es)
NO (1) NO20073148L (es)
NZ (1) NZ555640A (es)
PE (1) PE20061145A1 (es)
RU (1) RU2431486C2 (es)
TW (1) TW200637611A (es)
WO (1) WO2006061156A2 (es)

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DE102007055341A1 (de) 2007-11-19 2009-05-20 Bayer Animal Health Gmbh Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren
GR20090100230A (el) 2009-04-14 2010-11-18 Casso Pharmaceuticals Ε.Π.Ε, Απο του στοματος εναιωρημα οξικης δεξαμεθανοζης-συνθεση καλυψης γευσης της δεξαμεθανοζης
WO2013106230A1 (en) * 2012-01-10 2013-07-18 Entrx LLC Otic formulations, methods and devices
US9849126B2 (en) 2013-01-03 2017-12-26 Entrx LLC Sterile otic formulations
MD4291C1 (ro) * 2013-12-27 2015-02-28 Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова Preparat medicamentos pentru tratamentul otitelor
MX395029B (es) 2015-12-29 2025-03-24 Galderma Sa Metodo para desacetilacion de biopolimeros.
EP3478269A4 (en) * 2016-06-29 2020-04-08 Otonomy, Inc. OTIC FORMULATIONS BASED ON TRIGLYCERIDES AND THEIR USES
ES2886088T3 (es) * 2017-02-13 2021-12-16 Bayer Animal Health Gmbh Composición líquida que contiene pradofloxacina
PE20201257A1 (es) 2018-04-25 2020-11-16 Bayer Animal Health Gmbh Proceso para la hidrolisis de esteres carboxilicos de quinolona
TWI834808B (zh) * 2019-02-19 2024-03-11 西班牙商薩爾瓦特實驗室有限公司 以單劑包裝的克氯黴唑液體組成物
TWI894176B (zh) * 2019-10-28 2025-08-21 瑞士商葛德瑪控股公司 即用型美容組成物
RU2758056C2 (ru) * 2019-11-21 2021-10-26 федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный аграрный университет" Препарат для лечения отитов бактериальной и грибковой этиологии у собак
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Also Published As

Publication number Publication date
MX2007006689A (es) 2007-08-14
AR052990A1 (es) 2007-04-18
RU2431486C2 (ru) 2011-10-20
AU2005313602A1 (en) 2006-06-15
KR20070086799A (ko) 2007-08-27
BRPI0518855A2 (pt) 2008-12-09
TW200637611A (en) 2006-11-01
RU2007125570A (ru) 2009-01-20
NO20073148L (no) 2007-08-22
CA2594103A1 (en) 2006-06-15
WO2006061156A2 (de) 2006-06-15
DE102005055385A1 (de) 2006-06-14
GT200500361A (es) 2006-11-07
WO2006061156A3 (de) 2006-08-24
CR9142A (es) 2007-12-04
EP1830803A2 (de) 2007-09-12
US20090011045A1 (en) 2009-01-08
NZ555640A (en) 2009-12-24
IL183744A0 (en) 2008-04-13
JP2008522998A (ja) 2008-07-03

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