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RU2007117790A - ACID AND BUFFER SKIN CARE COMPOSITIONS CONTAINING NICOTINOMIDE AND ABSORBING AGENT - Google Patents

ACID AND BUFFER SKIN CARE COMPOSITIONS CONTAINING NICOTINOMIDE AND ABSORBING AGENT Download PDF

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Publication number
RU2007117790A
RU2007117790A RU2007117790/15A RU2007117790A RU2007117790A RU 2007117790 A RU2007117790 A RU 2007117790A RU 2007117790/15 A RU2007117790/15 A RU 2007117790/15A RU 2007117790 A RU2007117790 A RU 2007117790A RU 2007117790 A RU2007117790 A RU 2007117790A
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RU
Russia
Prior art keywords
composition
composition according
medicine
weight
agent
Prior art date
Application number
RU2007117790/15A
Other languages
Russian (ru)
Other versions
RU2401100C2 (en
Inventor
Франсуаза ДЕПЕРРА (FR)
Франсуаза ДЕПЕРРА
Сюзанна ГОСДШАН-АМАНН (CH)
Сюзанна ГОСДШАН-АМАНН
Original Assignee
Байер Конзюмер Кер АГ (CH)
Байер Конзюмер Кер АГ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Байер Конзюмер Кер АГ (CH), Байер Конзюмер Кер АГ filed Critical Байер Конзюмер Кер АГ (CH)
Publication of RU2007117790A publication Critical patent/RU2007117790A/en
Application granted granted Critical
Publication of RU2401100C2 publication Critical patent/RU2401100C2/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/315Zinc compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/29Titanium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/75Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (16)

1. Кислая и буферная композиция, содержащая1. Acid and buffer composition containing a) от 0,1 до 4% от массы композиции никотинамида; иa) from 0.1 to 4% by weight of the nicotinamide composition; and b) от 5 до 20% от массы композиции абсорбирующего агента, выбранного из группы, состоящей из диоксида титана, диоксида титана, обработанного силиконовым производным или жирными кислотами, оксида цинка, обработанного силиконовым производным или жирными кислотами, или их смеси.b) from 5 to 20% by weight of an absorbent agent composition selected from the group consisting of titanium dioxide, titanium dioxide treated with a silicone derivative or fatty acids, zinc oxide treated with a silicone derivative or fatty acids, or a mixture thereof. 2. Композиция по п.1, отличающаяся тем, что композиция содержит от 5 до 15% от массы композиции упомянутого абсорбирующего агента.2. The composition according to claim 1, characterized in that the composition contains from 5 to 15% by weight of the composition of said absorbent agent. 3. Композиция по п.1, отличающаяся тем, что абсорбирующим агентом является диоксид титана.3. The composition according to claim 1, characterized in that the absorbing agent is titanium dioxide. 4. Композиция по п.1, отличающаяся тем, что композиция содержит от 0,3 до 2,5% от массы композиции никотинамида.4. The composition according to claim 1, characterized in that the composition contains from 0.3 to 2.5% by weight of the composition of nicotinamide. 5. Композиция по п.1, отличающаяся тем, что композиция имеет значение рН в диапазоне от 4 до 7.5. The composition according to claim 1, characterized in that the composition has a pH value in the range from 4 to 7. 6. Композиция по п.1, отличающаяся тем, что композиция также содержит физиологические кожные липиды, другие витамины, противозудный агент и/или увлажняющие агенты.6. The composition according to claim 1, characterized in that the composition also contains physiological skin lipids, other vitamins, an antipruritic agent and / or moisturizing agents. 7. Композиция по п.6, отличающаяся тем, что в качестве других витаминов она содержит декспантенол и витамин Е.7. The composition according to claim 6, characterized in that as other vitamins it contains dexpanthenol and vitamin E. 8. Композиция по п.1, отличающаяся тем, что композиция является эмульсией типа «масло в воде».8. The composition according to claim 1, characterized in that the composition is an oil-in-water emulsion. 9. Композиция по п.1, отличающаяся тем, что композиция свободна от консерванта и этанола.9. The composition according to claim 1, characterized in that the composition is free of preservative and ethanol. 10. Композиция по любому из пп.1-9, имеющая буферную емкость, отличающаяся тем, что если 10 г композиции развести в 100 мл воды, и 50 мл этого раствора оттитровать водным раствором 0,1М аммиака, то более чем 3 мл раствора аммиака потребуется для достижения рН 8.10. The composition according to any one of claims 1 to 9, having a buffer capacity, characterized in that if 10 g of the composition is diluted in 100 ml of water, and 50 ml of this solution is titrated with an aqueous solution of 0.1 M ammonia, then more than 3 ml of ammonia solution required to achieve a pH of 8. 11. Композиция по одному любому из пп.1-9 для использования в качестве лекарственного средства.11. The composition according to any one of claims 1 to 9 for use as a medicine. 12. Композиция по п.10 для использования в качестве лекарственного средства.12. The composition of claim 10 for use as a medicine. 13. Композиция по п.11 для использования в качестве лекарственного средства для лечения и/или предотвращения пеленочного дерматита.13. The composition according to claim 11 for use as a medicine for the treatment and / or prevention of diaper dermatitis. 14. Композиция по п.12 для использования в качестве лекарственного средства для лечения и/или предотвращения пеленочного дерматита.14. The composition according to p. 12 for use as a medicine for the treatment and / or prevention of diaper dermatitis. 15. Применение композиции по любому из пп.1-10 в качестве антиуреазного агента.15. The use of a composition according to any one of claims 1 to 10 as an anti-urine agent. 16. Применение композиции по любому из пп.1-10 для производства лекарственного средства для лечения и/или предотвращения пеленочного дерматита.16. The use of a composition according to any one of claims 1 to 10 for the manufacture of a medicament for the treatment and / or prevention of diaper dermatitis.
RU2007117790/15A 2004-10-15 2005-10-05 Acid and buffer skin care compositions containing nicotinamide and absorbing agent RU2401100C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04292455.5 2004-10-15
EP04292455 2004-10-15

Publications (2)

Publication Number Publication Date
RU2007117790A true RU2007117790A (en) 2008-11-20
RU2401100C2 RU2401100C2 (en) 2010-10-10

Family

ID=34931458

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007117790/15A RU2401100C2 (en) 2004-10-15 2005-10-05 Acid and buffer skin care compositions containing nicotinamide and absorbing agent

Country Status (8)

Country Link
EP (1) EP1802296A1 (en)
AR (1) AR053978A1 (en)
AU (1) AU2005293830B2 (en)
BR (1) BRPI0518160A (en)
MX (1) MX2007004280A (en)
RU (1) RU2401100C2 (en)
TW (1) TW200626135A (en)
WO (1) WO2006040048A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2742942B1 (en) * 2012-12-14 2019-05-22 Unilever N.V. Niacinamide for inducing generation of antimicrobial peptides
CN113908074A (en) * 2014-05-12 2022-01-11 联合利华知识产权控股有限公司 Nicotinamide for Inducing Antimicrobial Peptide Production
FR3066194B1 (en) * 2017-05-12 2020-01-31 Societe D'exploitation De Produits Pour Les Industries Chimiques Seppic PROCESS FOR THE SYNTHESIS OF N-ACYLATED AMINO ACIDS WITHOUT USING SOLVENTS OR ACID CHLORIDE
JP6997222B2 (en) 2017-06-23 2022-01-17 ザ プロクター アンド ギャンブル カンパニー Compositions and Methods for Improving the Appearance of the Skin
US10874600B2 (en) 2018-06-18 2020-12-29 The Procter & Gamble Company Method for degrading bilirubin in skin
EP3817717A1 (en) 2018-07-03 2021-05-12 The Procter & Gamble Company Method of treating a skin condition
CN118662377A (en) 2020-01-24 2024-09-20 宝洁公司 Skin care composition
US10959933B1 (en) 2020-06-01 2021-03-30 The Procter & Gamble Company Low pH skin care composition and methods of using the same
JP7590462B2 (en) 2020-06-01 2024-11-26 ザ プロクター アンド ギャンブル カンパニー Method for improving skin penetration of vitamin B3 compounds
JP7620098B2 (en) 2020-12-14 2025-01-22 ザ プロクター アンド ギャンブル カンパニー Methods and compositions for treating oxidative stress in the skin
WO2025228657A1 (en) * 2024-05-02 2025-11-06 Unilever Ip Holdings B.V. A personal care composition
CN120437017A (en) * 2025-07-14 2025-08-08 拉芳家化股份有限公司 A macromolecular nicotinamide composite composition and its preparation method and application

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101492A0 (en) * 1992-04-03 1992-12-30 Shalom Levy Anti-skin rash preparation
US5759524A (en) * 1996-02-09 1998-06-02 The Procter & Gamble Company Photoprotective compositions
WO1999047141A1 (en) * 1998-03-16 1999-09-23 The Procter & Gamble Company Method of treating skin irritation
BR9917188A (en) * 1999-03-03 2002-01-02 Procter & Gamble Composition for skin care
US6444647B1 (en) * 1999-04-19 2002-09-03 The Procter & Gamble Company Skin care compositions containing combination of skin care actives
JP2002003378A (en) * 2000-06-22 2002-01-09 Kanebo Ltd External antipruritic agent
DE10063090A1 (en) * 2000-12-18 2002-06-20 Henkel Kgaa Nanoscale ZnO in hygiene products
US6936241B2 (en) * 2001-08-17 2005-08-30 The Procter & Gamble Company Sunscreen composition
DE10209110A1 (en) * 2002-03-01 2003-09-11 Beiersdorf Ag Stick for skin treatment (e.g. of diaper rash) has high pigmentary zinc oxide concentration combined with low or zero preservative concentration on account of low aqueous phase concentration
US7655717B2 (en) * 2002-07-17 2010-02-02 Mary J. Goulbourne Ointment composition for treating decubitus ulcers and methods for its making and its use
US20040167479A1 (en) * 2003-02-20 2004-08-26 The Procter & Gamble Company Hemorrhoid treatment pad

Also Published As

Publication number Publication date
AR053978A1 (en) 2007-05-30
WO2006040048A1 (en) 2006-04-20
MX2007004280A (en) 2007-05-16
AU2005293830B2 (en) 2010-10-21
BRPI0518160A (en) 2008-11-04
EP1802296A1 (en) 2007-07-04
RU2401100C2 (en) 2010-10-10
TW200626135A (en) 2006-08-01
AU2005293830A1 (en) 2006-04-20

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20131006