[go: up one dir, main page]

RU2006101787A - METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE YRBG GENE IS INACTIVATED - Google Patents

METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE YRBG GENE IS INACTIVATED Download PDF

Info

Publication number
RU2006101787A
RU2006101787A RU2006101787/13A RU2006101787A RU2006101787A RU 2006101787 A RU2006101787 A RU 2006101787A RU 2006101787/13 A RU2006101787/13 A RU 2006101787/13A RU 2006101787 A RU2006101787 A RU 2006101787A RU 2006101787 A RU2006101787 A RU 2006101787A
Authority
RU
Russia
Prior art keywords
amino acid
aromatic
producing
group
bacterium
Prior art date
Application number
RU2006101787/13A
Other languages
Russian (ru)
Other versions
RU2330881C2 (en
Inventor
Дмитрий Владимирович Филиппов (RU)
Дмитрий Владимирович Филиппов
Эльвира Борисовна Ворошилова (RU)
Эльвира Борисовна Ворошилова
тинер Михаил Маркович Гус (RU)
Михаил Маркович Гусятинер
Original Assignee
Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU)
Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU), Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) filed Critical Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU)
Priority to RU2006101787/13A priority Critical patent/RU2330881C2/en
Priority to PCT/JP2007/051342 priority patent/WO2007086547A1/en
Publication of RU2006101787A publication Critical patent/RU2006101787A/en
Application granted granted Critical
Publication of RU2330881C2 publication Critical patent/RU2330881C2/en

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Claims (11)

1. Бактерия-продуцент L-аминокислоты, принадлежащая к семейству Enterobacteriaceae, модифицированная таким образом, что экспрессия гена yrbG в указанной бактерии ослаблена.1. Bacteria producing L-amino acids belonging to the family Enterobacteriaceae, modified so that the expression of the yrbG gene in the specified bacteria is weakened. 2. Бактерия по п.1, отличающаяся тем, что экспрессия указанного гена yrbG ослаблена за счет инактивации указанного гена yrbG.2. The bacterium according to claim 1, characterized in that the expression of the specified yrbG gene is weakened due to the inactivation of the specified yrbG gene. 3. Бактерия по п.1, отличающаяся тем, что указанная бактерия принадлежит к роду Escherichia.3. The bacterium according to claim 1, characterized in that said bacterium belongs to the genus Escherichia. 4. Бактерия по п.1, отличающаяся тем, что указанная бактерия принадлежит к роду Pantoea.4. The bacterium according to claim 1, characterized in that said bacterium belongs to the genus Pantoea. 5. Бактерия-продуцент L-аминокислоты по любому из пп.1-4, отличающаяся тем, что указанная L-аминокислота выбрана из группы, состоящей из ароматической L-аминокислоты и неароматической L-аминокислоты.5. The bacterium producing L-amino acids according to any one of claims 1 to 4, characterized in that said L-amino acid is selected from the group consisting of aromatic L-amino acids and non-aromatic L-amino acids. 6. Бактерия-продуцент L-аминокислоты по п.5, отличающаяся тем, что указанная ароматическая L-аминокислота выбрана из группы, состоящей из L-фенилаланина, L-тирозина и L-триптофана.6. The L-amino acid producing bacterium according to claim 5, characterized in that said aromatic L-amino acid is selected from the group consisting of L-phenylalanine, L-tyrosine and L-tryptophan. 7. Бактерия-продуцент L-аминокислоты по п.5, отличающаяся тем, что указанная неароматическая L-аминокислота выбрана из группы, состоящей из L-треонина, L-лизина, L-цистеина, L-метионина, L-лейцина, L-изолейцина, L-валина, L-гистидина, L-глицина, L-серина, L-аланина, L-аспарагина, L-аспартата, L-глутамина, L-глутаминовой кислоты, L-пролина и L-аргинина.7. The L-amino acid producing bacterium according to claim 5, characterized in that said non-aromatic L-amino acid is selected from the group consisting of L-threonine, L-lysine, L-cysteine, L-methionine, L-leucine, L- isoleucine, L-valine, L-histidine, L-glycine, L-serine, L-alanine, L-asparagine, L-aspartate, L-glutamine, L-glutamic acid, L-proline and L-arginine. 8. Способ получения L-аминокислоты, включающий выращивание бактерии по любому из пп.1-7 в питательной среде, вызывающее продукцию и накопление указанной L-аминокислоты в культуральной жидкости, и выделение указанной L-аминокислоты из культуральной жидкости.8. A method for producing an L-amino acid, comprising growing a bacterium according to any one of claims 1 to 7 in a nutrient medium, causing production and accumulation of said L-amino acid in the culture fluid, and isolation of said L-amino acid from the culture fluid. 9. Способ по п.8, отличающийся тем, что указанная L-аминокислота выбрана из группы, состоящей из ароматической L-аминокислоты и неароматической L-аминокислоты.9. The method of claim 8, wherein said L-amino acid is selected from the group consisting of an aromatic L-amino acid and a non-aromatic L-amino acid. 10. Способ по п.9, отличающийся тем, что указанная ароматическая L-аминокислота выбрана из группы, состоящей из L-фенилаланина, L-тирозина и L-триптофана.10. The method according to claim 9, characterized in that said aromatic L-amino acid is selected from the group consisting of L-phenylalanine, L-tyrosine and L-tryptophan. 11. Способ по п.9, отличающийся тем, что указанная неароматическая L-аминокислота выбрана из группы, состоящей из L-треонина, L-лизина, L-цистеина, L-метионина, L-лейцина, L-изолейцина, L-валина, L-гистидина, L-глицина, L-серина, L-аланина, L-аспарагина, L-аспартата, L-глутамина, L-глутаминовой кислоты, L-пролина и L-аргинина.11. The method according to claim 9, characterized in that said non-aromatic L-amino acid is selected from the group consisting of L-threonine, L-lysine, L-cysteine, L-methionine, L-leucine, L-isoleucine, L-valine , L-histidine, L-glycine, L-serine, L-alanine, L-asparagine, L-aspartate, L-glutamine, L-glutamic acid, L-proline and L-arginine.
RU2006101787/13A 2006-01-24 2006-01-24 L-THREONINE TECHNIQUE USING BACTERIUM OF Escherichia GENUS WITH INACTIVATED yrbG GENE RU2330881C2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
RU2006101787/13A RU2330881C2 (en) 2006-01-24 2006-01-24 L-THREONINE TECHNIQUE USING BACTERIUM OF Escherichia GENUS WITH INACTIVATED yrbG GENE
PCT/JP2007/051342 WO2007086547A1 (en) 2006-01-24 2007-01-23 A METHOD FOR PRODUCING AN L-AMINO ACID USING A BACTERIUM OF ENTEROBACTERIACEAE FAMILY WITH ATTENUATED EXPRESSION OF THE yrbG GENE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2006101787/13A RU2330881C2 (en) 2006-01-24 2006-01-24 L-THREONINE TECHNIQUE USING BACTERIUM OF Escherichia GENUS WITH INACTIVATED yrbG GENE

Publications (2)

Publication Number Publication Date
RU2006101787A true RU2006101787A (en) 2007-07-27
RU2330881C2 RU2330881C2 (en) 2008-08-10

Family

ID=38431529

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006101787/13A RU2330881C2 (en) 2006-01-24 2006-01-24 L-THREONINE TECHNIQUE USING BACTERIUM OF Escherichia GENUS WITH INACTIVATED yrbG GENE

Country Status (1)

Country Link
RU (1) RU2330881C2 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS575693A (en) * 1980-06-13 1982-01-12 Ajinomoto Co Inc Production of l-arginine through fermentation process
SU1694643A1 (en) * 1987-11-26 1991-11-30 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Strain of bacteria escherichia coli - a producer of l-threonine

Also Published As

Publication number Publication date
RU2330881C2 (en) 2008-08-10

Similar Documents

Publication Publication Date Title
RU2004137198A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae Family In Which The yafA Gene Is Inactivated
RU2006143864A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF GENES cynT, cynS, cynX, OR cynR, OR THEIR COMBINATION IS DECREASED
RU2005101110A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE Glycogen biosynthesis pathway has been destroyed
RU2006123752A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE FAMILY Enterobacteriaceae, IN WHICH EXPRESSION OF THE OPERON rspAB IS DECREASED
RU2007104648A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF THE tolC GENE IS DECREASED
RU2007128314A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE yncD GENE IS DECREASED
RU2006100896A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE yfeH GENE IS INACTIVATED
RU2006100895A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE lrhA GENE IS INACTIVATED
RU2005106347A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE NAC GENE IS INACTIVATED
RU2005123423A (en) Bacteria of the Enterobacteriaceae family in which the pnp gene is inactivated, the producer of L-amino acids and the method for producing L-amino acids
RU2007106185A (en) BACTERIA OF THE FAMILY ENTEPOBACTERIACEAE, WHICH EXPRESSION OF THE OPERON YcbPONME (SSUEADCB) WAS WEARED, IS A PRODUCER OF L-AMINO ACID AND A METHOD FOR PRODUCING L-AMINO ACID
RU2007104650A (en) BACTERIA OF THE ENTERODACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE OPERON YhcA-E, PRODUCER OF L-AMINO ACID AND METHOD FOR PRODUCING L-AMINO ACID, WAS WEARED
RU2006123753A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE Enterobacteriaceae Family In Which Expression Of The yraH-R Gene Cluster Is Weakened
RU2006101787A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE YRBG GENE IS INACTIVATED
RU2006118967A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE ENTEROBACTERIACEAE FAMILY IN WHICH EXPRESSION OF THE RCSA GENE IS WEAKEN
RU2005138194A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE YAFA GENE IS INACTIVATED
RU2005114823A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE KefB GENE IS INACTIVATED
RU2005106346A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE LEUO GENE IS INACTIVATED
RU2006101788A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE fdrA GENE IS INACTIVATED
RU2005123419A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE CPXR GENE IS INACTIVATED
RU2005107202A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH SANA GENE IS INACTIVATED
RU2006112625A (en) METHOD FOR PRODUCING L-AMINO ACID USING THE Enterobacteriaceae Bacteria in Which the Expression of the fhuA Gene Is Weakened
RU2007112271A (en) METHOD FOR PRODUCING L-Amino Acids USING THE Enterobacteriaceae Bacteria in Which Expression of the ygiD Gene Is Weakened
RU2005104458A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE BOLA GENE IS INACTIVATED
RU2005104462A (en) METHOD FOR PRODUCING L-AMINO ACIDS USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH YOEB GENE IS INACTIVATED