RU2004110616A - Ингибитор матриксных металлопротеиназ - Google Patents
Ингибитор матриксных металлопротеиназ Download PDFInfo
- Publication number
- RU2004110616A RU2004110616A RU2004110616/15A RU2004110616A RU2004110616A RU 2004110616 A RU2004110616 A RU 2004110616A RU 2004110616/15 A RU2004110616/15 A RU 2004110616/15A RU 2004110616 A RU2004110616 A RU 2004110616A RU 2004110616 A RU2004110616 A RU 2004110616A
- Authority
- RU
- Russia
- Prior art keywords
- inhibitor
- extract
- matrix metalloproteinases
- matrix metalloproteinase
- ganoderma
- Prior art date
Links
- 229940121386 matrix metalloproteinase inhibitor Drugs 0.000 title claims 2
- 239000003771 matrix metalloproteinase inhibitor Substances 0.000 title claims 2
- 102000002274 Matrix Metalloproteinases Human genes 0.000 claims abstract 8
- 108010000684 Matrix Metalloproteinases Proteins 0.000 claims abstract 8
- 206010027476 Metastases Diseases 0.000 claims abstract 5
- 230000009401 metastasis Effects 0.000 claims abstract 5
- 239000002904 solvent Substances 0.000 claims abstract 5
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims abstract 4
- 241000222336 Ganoderma Species 0.000 claims abstract 4
- 239000003814 drug Substances 0.000 claims abstract 3
- 239000003112 inhibitor Substances 0.000 claims 5
- 241000906988 Ganoderma atrum Species 0.000 claims 4
- 230000002001 anti-metastasis Effects 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 150000001298 alcohols Chemical class 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 150000005846 sugar alcohols Polymers 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 6
- 201000010099 disease Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 230000003449 preventive effect Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 230000006399 behavior Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 201000001245 periodontitis Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 230000001629 suppression Effects 0.000 abstract 1
- 230000036269 ulceration Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Birds (AREA)
- Communicable Diseases (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Immunology (AREA)
Claims (6)
1. Ингибитор матриксных металлопротеиназ, содержащий экстракт гриба Ganoderma.
2. Ингибитор матриксных металлопротеиназ, содержащий экстракт гриба Ganoderma atrum.
3. Ингибитор матриксных металлопротеиназ по любому из пп.1-2, отличающийся тем, что экстрагирующим растворителем является один или более растворителей, выбираемых из группы, состоящей из воды, низших спиртов и жидких многоатомных спиртов.
4. Лекарственные препараты, супрессоры метастазирования, содержащие ингибитор матриксных металлопротеиназ, который включает экстракт гриба Ganoderma atrum, и применяемые для подавления метастазирования.
5. Косметические средства, содержащие ингибитор матриксных металлопротеиназ, который включает экстракт гриба Ganoderma atrum, и применяемые как антиметастатические или подавляющие метастазирование средства.
6. Пищевые продукты, содержащие ингибитор матриксных металлопротеиназ, который включает экстракт гриба Ganoderma atrum, и применяемые как антиметастатические или подавляющие метастазирование средства.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001297672 | 2001-09-27 | ||
| JP2001-297672 | 2001-09-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2004110616A true RU2004110616A (ru) | 2005-04-20 |
| RU2283125C2 RU2283125C2 (ru) | 2006-09-10 |
Family
ID=19118704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004110616/15A RU2283125C2 (ru) | 2001-09-27 | 2002-09-27 | Ингибитор матриксных металлопротеиназ |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7618638B2 (ru) |
| EP (1) | EP1449534B1 (ru) |
| KR (1) | KR100644357B1 (ru) |
| CN (1) | CN100518747C (ru) |
| AT (1) | ATE506070T1 (ru) |
| CA (1) | CA2460834C (ru) |
| DE (1) | DE60239822D1 (ru) |
| ES (1) | ES2365132T3 (ru) |
| RU (1) | RU2283125C2 (ru) |
| TW (1) | TWI318881B (ru) |
| WO (1) | WO2003028749A1 (ru) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10166270B2 (en) | 2004-04-23 | 2019-01-01 | Zivo Bioscience, Inc. | Composition and method for affecting cytokines and NF-κB |
| US7807622B2 (en) | 2004-04-23 | 2010-10-05 | Health Enhancement Products, Inc. | Composition and use of phyto-percolate for treatment of disease |
| CA2625818A1 (en) * | 2005-04-20 | 2006-10-26 | Health Enhancement Products, Inc. | Composition and use of phyto-percolate for treatment of disease |
| JP2007045713A (ja) * | 2005-08-05 | 2007-02-22 | Iskra Ind Co Ltd | 霊芝胞子抽出物及び霊芝胞子製剤 |
| CN102813672B (zh) * | 2009-05-27 | 2013-11-06 | 西北大学 | 硫酸铝铵十二水在制备抗肿瘤基质金属蛋白酶抑制剂中的应用 |
| US9486005B2 (en) | 2010-02-22 | 2016-11-08 | Smiti Vaid Gupta | Agents and mechanisms for treating hypercholesterolemia |
| WO2014094918A1 (en) * | 2012-12-21 | 2014-06-26 | Aqua Bio Technology Asa | Cosmetic compositions from fish hatching fluid |
| US10232028B2 (en) | 2013-06-13 | 2019-03-19 | Zivo Bioscience, Inc. | Compounds and methods for affecting cytokines |
| EP3258948B1 (en) | 2015-02-16 | 2023-12-06 | Zivo Bioscience, Inc. | Anti-inflammatory and immunomodulatory compositions comprising klebsormidium and uses thereof |
| EP3416501A4 (en) | 2016-02-16 | 2019-11-20 | Zivo Bioscience, Inc. | NUTRITIONAL SUPPLEMENT FOR ANIMALS BY ADMINISTERING A FOOD SUPPLEMENT FROM ALGAE |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62239953A (ja) | 1986-04-11 | 1987-10-20 | Yasahiro Morita | 霊芝茶の製造法 |
| JPH06345636A (ja) | 1993-06-08 | 1994-12-20 | Nonogawa Shoji Kk | 化粧料 |
| JPH0873369A (ja) | 1994-09-01 | 1996-03-19 | Fuairudo:Kk | 健康茶 |
| US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
| JP3611638B2 (ja) * | 1995-08-02 | 2005-01-19 | カネボウ株式会社 | ヒトコラゲナーゼ活性阻害剤 |
| JPH09235293A (ja) * | 1996-02-29 | 1997-09-09 | Kanebo Ltd | 新規トリテルペン |
| CN1058190C (zh) * | 1996-05-07 | 2000-11-08 | 陈帅民 | 一种记忆口服液 |
| JPH11139947A (ja) | 1997-11-11 | 1999-05-25 | Sunstar Inc | マトリックスメタロプロテアーゼ阻害剤含有口腔用組成物 |
| JPH11180889A (ja) | 1997-12-15 | 1999-07-06 | Buhei Kono | 霊芝からの抽出成分を含有する皮膚炎治療用薬液 |
| CN1291511A (zh) | 1999-10-10 | 2001-04-18 | 四川三优奇康产业股份有限公司 | 纯天然抗癌转移制剂 |
-
2002
- 2002-09-26 TW TW091122126A patent/TWI318881B/zh not_active IP Right Cessation
- 2002-09-27 EP EP02800257A patent/EP1449534B1/en not_active Expired - Lifetime
- 2002-09-27 AT AT02800257T patent/ATE506070T1/de not_active IP Right Cessation
- 2002-09-27 DE DE60239822T patent/DE60239822D1/de not_active Expired - Lifetime
- 2002-09-27 CA CA2460834A patent/CA2460834C/en not_active Expired - Lifetime
- 2002-09-27 WO PCT/JP2002/010006 patent/WO2003028749A1/ja not_active Ceased
- 2002-09-27 KR KR1020047004478A patent/KR100644357B1/ko not_active Expired - Lifetime
- 2002-09-27 ES ES02800257T patent/ES2365132T3/es not_active Expired - Lifetime
- 2002-09-27 CN CNB028190319A patent/CN100518747C/zh not_active Expired - Lifetime
- 2002-09-27 RU RU2004110616/15A patent/RU2283125C2/ru active
- 2002-09-27 US US10/490,317 patent/US7618638B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003028749A1 (fr) | 2003-04-10 |
| US20050037024A1 (en) | 2005-02-17 |
| CA2460834A1 (en) | 2003-04-10 |
| CN100518747C (zh) | 2009-07-29 |
| KR100644357B1 (ko) | 2006-11-10 |
| ATE506070T1 (de) | 2011-05-15 |
| EP1449534A4 (en) | 2006-01-11 |
| TWI318881B (ru) | 2010-01-01 |
| RU2283125C2 (ru) | 2006-09-10 |
| US7618638B2 (en) | 2009-11-17 |
| CN1561222A (zh) | 2005-01-05 |
| HK1072564A1 (zh) | 2005-09-02 |
| DE60239822D1 (de) | 2011-06-01 |
| CA2460834C (en) | 2011-10-25 |
| KR20040041629A (ko) | 2004-05-17 |
| EP1449534B1 (en) | 2011-04-20 |
| ES2365132T3 (es) | 2011-09-22 |
| EP1449534A1 (en) | 2004-08-25 |
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