PT98747A - Processo para a preparacao de 6,7-dihidro-3-fenil-1-1,2-benzisoxazol-4(5h)-onase -ois e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de 6,7-dihidro-3-fenil-1-1,2-benzisoxazol-4(5h)-onase -ois e de composicoes farmaceuticas que os contem

Info

Publication number: PT98747A
Authority: PT; Portugal
Prior art keywords: chem; formula; loweralkyl; hydrogen; arylloweralkyl
Prior art date: 1990-08-23

Application number

PT98747A

Other languages

English (en)

Other versions

PT98747B (pt

Inventor

David Gordon Wettlaufer

Gregory Michael Shutske

Peter Allen Nemoto

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-23

Filing date

1991-08-22

Publication date

1992-07-31

1991-08-22 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1992-07-31 Publication of PT98747A publication Critical patent/PT98747A/pt

1999-01-29 Publication of PT98747B publication Critical patent/PT98747B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

PT98747A 1990-08-23 1991-08-22 Processo para a preparacao de 6,7-dihidro-3-fenil-1-1,2-benzisoxazol-4(5h)-onase -ois e de composicoes farmaceuticas que os contem PT98747B (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US57148290A	1990-08-23	1990-08-23
US07/692,341 US5114936A (en)	1990-08-23	1991-04-26	6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use

Publications (2)

Publication Number	Publication Date
PT98747A true PT98747A (pt)	1992-07-31
PT98747B PT98747B (pt)	1999-01-29

Family

ID=27075593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT98747A PT98747B (pt)	1990-08-23	1991-08-22	Processo para a preparacao de 6,7-dihidro-3-fenil-1-1,2-benzisoxazol-4(5h)-onase -ois e de composicoes farmaceuticas que os contem

Country Status (20)

Country	Link
US (1)	US5114936A (pt)
EP (1)	EP0474012B1 (pt)
JP (1)	JP3018619B2 (pt)
KR (1)	KR0173685B1 (pt)
AT (1)	ATE145644T1 (pt)
AU (1)	AU634944B2 (pt)
CA (1)	CA2049733C (pt)
CS (1)	CS260191A3 (pt)
DE (1)	DE69123315T2 (pt)
DK (1)	DK0474012T3 (pt)
ES (1)	ES2095277T3 (pt)
FI (1)	FI913957A7 (pt)
GR (1)	GR3022697T3 (pt)
HU (1)	HU215439B (pt)
IE (1)	IE76138B1 (pt)
IL (1)	IL99264A (pt)
NO (1)	NO913292L (pt)
NZ (1)	NZ239494A (pt)
PT (1)	PT98747B (pt)
YU (1)	YU142991A (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5114960A (en) *	1989-07-20	1992-05-19	Hoffmann-La Roche Inc.	Substituted isoxazole derivatives
US5225412A (en) *	1991-04-29	1993-07-06	Hoechst-Roussel Pharmaceuticals Incorporated	Benzoisothiazole-and benzisoxazole-3-carboxamides
US5143923B1 (en) *	1991-04-29	1993-11-02	Hoechst-Roussel Pharmaceuticals Incorporated	Benzoisothiazole-and benzisoxazole-3-carboxamides
GB2264299B (en) *	1992-02-19	1995-07-26	British Tech Group	Iso-oxazolidine derivatives
GB9226857D0 (en) *	1992-12-23	1993-02-17	Boyd Edward A	Pharmaceutical compositions
GB2284600A (en) *	1994-01-21	1995-06-14	Shell Int Research	Herbicidal 3-(hetero)aryl-4-acylisoxazole compositions and compounds
US7125903B1 (en)	1999-09-14	2006-10-24	Aventis Pharmaceuticals Inc.	Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists
US7253165B2 (en) *	1999-09-14	2007-08-07	Aventis Pharmaceuticals Inc.	Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists
DK1216244T3 (da) *	1999-09-14	2003-11-17	Aventis Pharma Inc	Benzisoxazolyl-, pyridoisoxazolyl- og benzothienylphenoxyderivater som D4-antagonister
US7091199B1 (en)	1999-09-14	2006-08-15	Aventis Pharmaceuticals Inc.	Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists
EP1484325B1 (en) *	2002-03-08	2014-06-18	Japan Science and Technology Agency	Isoxazole derivatives and process for producing the same
US6770659B2 (en)	2002-08-26	2004-08-03	Sk Corporation	Benzoyl piperidine compounds
WO2007108146A1 (ja)	2006-03-22	2007-09-27	Kabushiki Kaisha Tominaga Jyushi Kogyosho	水槽用オーバーフロー装置
US20100012559A1 (en)	2006-08-25	2010-01-21	Ryuzo Arita	Overflow device for water tank
ES2643557T3 (es) *	2012-09-14	2017-11-23	Supernus Pharmaceuticals, Inc.	Procedimientos de producción de molindona y sus sales
US10745401B2 (en)	2018-07-23	2020-08-18	Sumitomo Dainippon Pharma Co., Ltd.	Condensed lactam derivative
EA202190316A1 (ru)	2018-07-23	2021-05-20	Сумитомо Дайниппон Фарма Ко., Лтд.	Конденсированное производное лактама
WO2023083445A1 (en)	2021-11-10	2023-05-19	Symrise Ag	Compositions comprising trpm8 agonistic cooling agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4010176A (en) *	1972-10-27	1977-03-01	Merck & Co., Inc.	Isoxazole substituted nitroimidazoles
US4217349A (en) *	1974-07-01	1980-08-12	Sumitomo Chemical Company, Limited	Benzisoxazole derivatives
US4156005A (en) *	1978-06-21	1979-05-22	Merck & Co., Inc.	Derivatives of 1,2-benzisoxazoles
GB2024008B (en) *	1978-06-28	1983-02-16	Merck & Co Inc	Compositions for treating trypanosomiasis infections
EP0149229B1 (en) *	1981-04-27	1989-06-14	Hoechst-Roussel Pharmaceuticals Incorporated	3-(gamma-chloropropyl)-6-fluor-1,2-benzisoxazole, process for its preparation and its use as an intermediate
US4458075A (en) *	1982-04-09	1984-07-03	Hoechst-Roussel Pharmaceuticals Inc.	6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
IL66866A (en) *	1982-04-09	1987-08-31	Hoechst Roussel Pharma	1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and-piperidines,a process for the preparation thereof,and pharmaceutical compositions containing them
EP0189612B1 (en) *	1984-12-21	1992-11-04	Duphar International Research B.V	New pharmaceutical compositions having a psychotropic activity
HU208690B (en) *	1987-10-26	1993-12-28	Pfizer	Process for producing 1-hjeterocyclic sulfonyl-3-(pyrimidinyl piperazinyl)-propane derivatives and pharmaceutical compositions comprising same
US5114960A (en) *	1989-07-20	1992-05-19	Hoffmann-La Roche Inc.	Substituted isoxazole derivatives

1991
- 1991-04-26 US US07/692,341 patent/US5114936A/en not_active Expired - Fee Related
- 1991-08-19 AT AT91113867T patent/ATE145644T1/de not_active IP Right Cessation
- 1991-08-19 ES ES91113867T patent/ES2095277T3/es not_active Expired - Lifetime
- 1991-08-19 EP EP91113867A patent/EP0474012B1/en not_active Expired - Lifetime
- 1991-08-19 DE DE69123315T patent/DE69123315T2/de not_active Expired - Fee Related
- 1991-08-19 DK DK91113867.5T patent/DK0474012T3/da active
- 1991-08-21 HU HU912756A patent/HU215439B/hu not_active IP Right Cessation
- 1991-08-21 IL IL9926491A patent/IL99264A/en active IP Right Grant
- 1991-08-21 FI FI913957A patent/FI913957A7/fi not_active Application Discontinuation
- 1991-08-21 YU YU142991A patent/YU142991A/sh unknown
- 1991-08-21 NZ NZ239494A patent/NZ239494A/en unknown
- 1991-08-22 NO NO91913292A patent/NO913292L/no unknown
- 1991-08-22 JP JP3210691A patent/JP3018619B2/ja not_active Expired - Fee Related
- 1991-08-22 AU AU82617/91A patent/AU634944B2/en not_active Ceased
- 1991-08-22 KR KR1019910014488A patent/KR0173685B1/ko not_active Expired - Fee Related
- 1991-08-22 CA CA002049733A patent/CA2049733C/en not_active Expired - Fee Related
- 1991-08-22 IE IE297691A patent/IE76138B1/en not_active IP Right Cessation
- 1991-08-22 PT PT98747A patent/PT98747B/pt not_active IP Right Cessation
- 1991-08-22 CS CS912601A patent/CS260191A3/cs unknown
1997
- 1997-02-27 GR GR970400378T patent/GR3022697T3/el unknown

Also Published As

Publication number	Publication date
HU215439B (hu)	1999-09-28
AU8261791A (en)	1991-11-07
EP0474012B1 (en)	1996-11-27
GR3022697T3 (en)	1997-05-31
FI913957A0 (fi)	1991-08-21
YU142991A (sh)	1995-01-31
KR0173685B1 (ko)	1999-02-01
HUT61533A (en)	1993-01-28
PT98747B (pt)	1999-01-29
EP0474012A1 (en)	1992-03-11
IL99264A (en)	1996-01-19
IE76138B1 (en)	1997-10-08
NO913292D0 (no)	1991-08-22
DE69123315D1 (de)	1997-01-09
FI913957L (fi)	1992-02-24
NZ239494A (en)	1994-08-26
DK0474012T3 (da)	1997-05-12
IL99264A0 (en)	1992-07-15
CS260191A3 (en)	1992-04-15
FI913957A7 (fi)	1992-02-24
IE912976A1 (en)	1992-02-26
ES2095277T3 (es)	1997-02-16
HU912756D0 (en)	1992-01-28
ATE145644T1 (de)	1996-12-15
KR920004366A (ko)	1992-03-27
CA2049733C (en)	2003-10-21
CA2049733A1 (en)	1992-02-24
JPH04230673A (ja)	1992-08-19
AU634944B2 (en)	1993-03-04
NO913292L (no)	1992-02-24
DE69123315T2 (de)	1997-05-22
US5114936A (en)	1992-05-19
JP3018619B2 (ja)	2000-03-13

Publication	Publication Date	Title
PT98747A (pt)	1992-07-31	Processo para a preparacao de 6,7-dihidro-3-fenil-1-1,2-benzisoxazol-4(5h)-onase -ois e de composicoes farmaceuticas que os contem
IL95568A0 (en)	1991-06-30	N-substituted-4-pyrimidinamines and pyrimidinidiamines,process for their preparation and pharmaceutical compositions containing them
BR1100514A (pt)	2002-04-02	Processo para a preparação de compostos derivados do ácido benzimidazolino - 2 - oxo - 1 - carboxìlico; produto / composto / composição
DE69522703D1 (de)	2001-10-18	Aminotetrazol-derivate verwendbar als stickstoff-oxid-synthase inhibitoren
ATE138377T1 (de)	1996-06-15	N-(aryloxyalkyl)heteroaryl-8- azabicyclo(3.2.1>octan, zwischenverbindungen und verfahren zu deren herstellung und deren verwendung als arzneimittel
IL99434A0 (en)	1992-08-18	3-(1h-indazol-3-yl)-4-pyridinamines,a process and intermediates for their preparation and pharmaceutical compositions containing them
AU646611B2 (en)	1994-02-24	4-{4- or 6-(trifluoromethyl-2-pyridinyl)}-1-piperazinyl- alkyl substituted lactams
BR9600979A (pt)	1997-12-30	Composto processo para combater fungos fitopatogênicos composição fungicida e processo de preparação de um composto
MY111604A (en)	2000-09-27	Piperidinyl compounds

Legal Events

Date	Code	Title	Description
1992-07-31	BB1A	Laying open of patent application	Effective date: 19920310
1999-01-29	FG3A	Patent granted, date of granting	Effective date: 19981027
2005-06-30	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20050427

Date

Code

Title

Description

1992-07-31

BB1A

Laying open of patent application

Effective date: 19920310

1999-01-29

FG3A

Patent granted, date of granting

Effective date: 19981027

2005-06-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20050427