FI913957L - 6,7-dihydro-3-fenyl-1,2 -bensisoxazol-4(5h)-oner och -oler, foerfarande foer framstaellning av dessa samt anvaendning av dessa som laekemedel. - Google Patents

6,7-dihydro-3-fenyl-1,2 -bensisoxazol-4(5h)-oner och -oler, foerfarande foer framstaellning av dessa samt anvaendning av dessa som laekemedel. Download PDF

Info

Publication number: FI913957L
Authority: FI; Finland
Prior art keywords: dessa; bensisoxazol; oler; oner; och
Prior art date: 1990-08-23

Application number

FI913957A

Other languages

English (en)

Other versions

FI913957A7 (fi

FI913957A0 (fi

Inventor

David Gordon Wettlaufer

Gregory Michael Shutske

Peter Allen Nemoto

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-23

Filing date

1991-08-21

Publication date

1992-02-24

1991-08-21 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1991-08-21 Publication of FI913957A0 publication Critical patent/FI913957A0/fi

1992-02-24 Publication of FI913957L publication Critical patent/FI913957L/fi

1992-02-24 Publication of FI913957A7 publication Critical patent/FI913957A7/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

FI913957A 1990-08-23 1991-08-21 6,7-dihydro-3-fenyyli-1,2-bentsisoksatsol-4(5H)-oneja ja -oleja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä FI913957A7 (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US57148290A	1990-08-23	1990-08-23
US07/692,341 US5114936A (en)	1990-08-23	1991-04-26	6,7-dihydro-3-phenyl-1,2-benzisoxazol-4(5h)-ones and -ols, compositions and pharmaceutical use

Publications (3)

Publication Number	Publication Date
FI913957A0 FI913957A0 (fi)	1991-08-21
FI913957L true FI913957L (fi)	1992-02-24
FI913957A7 FI913957A7 (fi)	1992-02-24

Family

ID=27075593

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI913957A FI913957A7 (fi)	1990-08-23	1991-08-21	6,7-dihydro-3-fenyyli-1,2-bentsisoksatsol-4(5H)-oneja ja -oleja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä

Country Status (20)

Country	Link
US (1)	US5114936A (fi)
EP (1)	EP0474012B1 (fi)
JP (1)	JP3018619B2 (fi)
KR (1)	KR0173685B1 (fi)
AT (1)	ATE145644T1 (fi)
AU (1)	AU634944B2 (fi)
CA (1)	CA2049733C (fi)
CS (1)	CS260191A3 (fi)
DE (1)	DE69123315T2 (fi)
DK (1)	DK0474012T3 (fi)
ES (1)	ES2095277T3 (fi)
FI (1)	FI913957A7 (fi)
GR (1)	GR3022697T3 (fi)
HU (1)	HU215439B (fi)
IE (1)	IE76138B1 (fi)
IL (1)	IL99264A (fi)
NO (1)	NO913292L (fi)
NZ (1)	NZ239494A (fi)
PT (1)	PT98747B (fi)
YU (1)	YU142991A (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5114960A (en) *	1989-07-20	1992-05-19	Hoffmann-La Roche Inc.	Substituted isoxazole derivatives
US5143923B1 (en) *	1991-04-29	1993-11-02	Hoechst-Roussel Pharmaceuticals Incorporated	Benzoisothiazole-and benzisoxazole-3-carboxamides
US5225412A (en) *	1991-04-29	1993-07-06	Hoechst-Roussel Pharmaceuticals Incorporated	Benzoisothiazole-and benzisoxazole-3-carboxamides
GB2264299B (en) *	1992-02-19	1995-07-26	British Tech Group	Iso-oxazolidine derivatives
GB9226857D0 (en) *	1992-12-23	1993-02-17	Boyd Edward A	Pharmaceutical compositions
GB2284600A (en) *	1994-01-21	1995-06-14	Shell Int Research	Herbicidal 3-(hetero)aryl-4-acylisoxazole compositions and compounds
US7253165B2 (en) *	1999-09-14	2007-08-07	Aventis Pharmaceuticals Inc.	Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists
US7125903B1 (en)	1999-09-14	2006-10-24	Aventis Pharmaceuticals Inc.	Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists
US7091199B1 (en)	1999-09-14	2006-08-15	Aventis Pharmaceuticals Inc.	Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists
MXPA02002694A (es) *	1999-09-14	2002-07-30	Aventis Pharm Prod Inc	Derivados de benzisoxazolil-, piridoisoxazolil-y benzotienil-fenoxi utiles como antagonistas de d4.
EP1484325B1 (en) *	2002-03-08	2014-06-18	Japan Science and Technology Agency	Isoxazole derivatives and process for producing the same
US6770659B2 (en)	2002-08-26	2004-08-03	Sk Corporation	Benzoyl piperidine compounds
JP4909343B2 (ja)	2006-03-22	2012-04-04	株式会社冨永樹脂工業所	水槽用濾過装置
EP2055186B1 (en)	2006-08-25	2011-10-26	Kabushiki Kaisha Tominaga Jyushi Kogyosho	Overflow device for water tank
AU2013316119B2 (en) *	2012-09-14	2017-05-04	Supernus Pharmaceuticals Inc.	Methods of producing molindone and its salts
US10745401B2 (en)	2018-07-23	2020-08-18	Sumitomo Dainippon Pharma Co., Ltd.	Condensed lactam derivative
KR102822532B1 (ko) *	2018-07-23	2025-06-19	스미토모 파마 가부시키가이샤	축환 락탐 유도체
EP4429465A1 (en)	2021-11-10	2024-09-18	Symrise AG	Compositions comprising trpm8 agonistic cooling agents

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4010176A (en) *	1972-10-27	1977-03-01	Merck & Co., Inc.	Isoxazole substituted nitroimidazoles
US4217349A (en) *	1974-07-01	1980-08-12	Sumitomo Chemical Company, Limited	Benzisoxazole derivatives
US4156005A (en) *	1978-06-21	1979-05-22	Merck & Co., Inc.	Derivatives of 1,2-benzisoxazoles
GB2024008B (en) *	1978-06-28	1983-02-16	Merck & Co Inc	Compositions for treating trypanosomiasis infections
DE3267658D1 (en) *	1981-04-27	1986-01-09	Hoechst Roussel Pharma	1-(3-(6-fluoro-1,2-benzisoxasol-3-yl)propyl)-4-hydroxy-4-phenylpiperidines, a process for their preparation and their use as medicaments
IL66866A (en) *	1982-04-09	1987-08-31	Hoechst Roussel Pharma	1-(3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl)-4-(substituted)-piperazines and-piperidines,a process for the preparation thereof,and pharmaceutical compositions containing them
US4458075A (en) *	1982-04-09	1984-07-03	Hoechst-Roussel Pharmaceuticals Inc.	6-Fluoro-3-[3-(1-heterocyclo)propyl]-1,2-benzisoxazoles
EP0189612B1 (en) *	1984-12-21	1992-11-04	Duphar International Research B.V	New pharmaceutical compositions having a psychotropic activity
MX173180B (es) *	1987-10-26	1994-02-07	Pfizer	Procedimiento para preparar agentes ansioliticos
US5114960A (en) *	1989-07-20	1992-05-19	Hoffmann-La Roche Inc.	Substituted isoxazole derivatives

1991
- 1991-04-26 US US07/692,341 patent/US5114936A/en not_active Expired - Fee Related
- 1991-08-19 DK DK91113867.5T patent/DK0474012T3/da active
- 1991-08-19 AT AT91113867T patent/ATE145644T1/de not_active IP Right Cessation
- 1991-08-19 DE DE69123315T patent/DE69123315T2/de not_active Expired - Fee Related
- 1991-08-19 EP EP91113867A patent/EP0474012B1/en not_active Expired - Lifetime
- 1991-08-19 ES ES91113867T patent/ES2095277T3/es not_active Expired - Lifetime
- 1991-08-21 IL IL9926491A patent/IL99264A/en active IP Right Grant
- 1991-08-21 FI FI913957A patent/FI913957A7/fi not_active Application Discontinuation
- 1991-08-21 HU HU912756A patent/HU215439B/hu not_active IP Right Cessation
- 1991-08-21 NZ NZ239494A patent/NZ239494A/en unknown
- 1991-08-21 YU YU142991A patent/YU142991A/sh unknown
- 1991-08-22 CS CS912601A patent/CS260191A3/cs unknown
- 1991-08-22 JP JP3210691A patent/JP3018619B2/ja not_active Expired - Fee Related
- 1991-08-22 NO NO91913292A patent/NO913292L/no unknown
- 1991-08-22 IE IE297691A patent/IE76138B1/en not_active IP Right Cessation
- 1991-08-22 PT PT98747A patent/PT98747B/pt not_active IP Right Cessation
- 1991-08-22 KR KR1019910014488A patent/KR0173685B1/ko not_active Expired - Fee Related
- 1991-08-22 AU AU82617/91A patent/AU634944B2/en not_active Ceased
- 1991-08-22 CA CA002049733A patent/CA2049733C/en not_active Expired - Fee Related
1997
- 1997-02-27 GR GR970400378T patent/GR3022697T3/el unknown

Also Published As

Publication number	Publication date
EP0474012B1 (en)	1996-11-27
GR3022697T3 (en)	1997-05-31
DE69123315T2 (de)	1997-05-22
NO913292L (no)	1992-02-24
HU215439B (hu)	1999-09-28
CA2049733A1 (en)	1992-02-24
IL99264A (en)	1996-01-19
CS260191A3 (en)	1992-04-15
DE69123315D1 (de)	1997-01-09
CA2049733C (en)	2003-10-21
NZ239494A (en)	1994-08-26
IL99264A0 (en)	1992-07-15
HUT61533A (en)	1993-01-28
JP3018619B2 (ja)	2000-03-13
KR0173685B1 (ko)	1999-02-01
PT98747B (pt)	1999-01-29
YU142991A (sh)	1995-01-31
IE912976A1 (en)	1992-02-26
PT98747A (pt)	1992-07-31
HU912756D0 (en)	1992-01-28
ATE145644T1 (de)	1996-12-15
FI913957A7 (fi)	1992-02-24
NO913292D0 (no)	1991-08-22
KR920004366A (ko)	1992-03-27
IE76138B1 (en)	1997-10-08
EP0474012A1 (en)	1992-03-11
JPH04230673A (ja)	1992-08-19
AU634944B2 (en)	1993-03-04
US5114936A (en)	1992-05-19
ES2095277T3 (es)	1997-02-16
DK0474012T3 (da)	1997-05-12
FI913957A0 (fi)	1991-08-21
AU8261791A (en)	1991-11-07

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Legal Events

Date	Code	Title	Description
1994-03-07	FD	Application lapsed