[go: up one dir, main page]

PT97971A - Processo para a preparacao de novas cefalosporinas possuindo um radiacl propenilo na posicao 3, substituido por um amonio quaternario e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de novas cefalosporinas possuindo um radiacl propenilo na posicao 3, substituido por um amonio quaternario e de composicoes farmaceuticas que os contem

Info

Publication number
PT97971A
PT97971A PT97971A PT9797191A PT97971A PT 97971 A PT97971 A PT 97971A PT 97971 A PT97971 A PT 97971A PT 9797191 A PT9797191 A PT 9797191A PT 97971 A PT97971 A PT 97971A
Authority
PT
Portugal
Prior art keywords
preparation
new
radiacl
propenylus
cefalosporines
Prior art date
Application number
PT97971A
Other languages
English (en)
Other versions
PT97971B (pt
Inventor
Jozsef Aszodi
Jean-Francois Chantot
Solange Govin D Ambrieres
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT97971A publication Critical patent/PT97971A/pt
Publication of PT97971B publication Critical patent/PT97971B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT97971A 1990-06-15 1991-06-14 Processo para a preparacao de novas cefalosporinas possuindo um radiacl propenilo na posicao 3, substituido por um amonio quaternario e de composicoes farmaceuticas que os contem PT97971B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007491A FR2663332B1 (fr) 1990-06-15 1990-06-15 Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.

Publications (2)

Publication Number Publication Date
PT97971A true PT97971A (pt) 1992-03-31
PT97971B PT97971B (pt) 1998-11-30

Family

ID=9397653

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97971A PT97971B (pt) 1990-06-15 1991-06-14 Processo para a preparacao de novas cefalosporinas possuindo um radiacl propenilo na posicao 3, substituido por um amonio quaternario e de composicoes farmaceuticas que os contem

Country Status (20)

Country Link
US (1) US5416080A (pt)
EP (1) EP0462009B1 (pt)
JP (1) JP3080692B2 (pt)
KR (1) KR960009266B1 (pt)
AT (1) ATE172733T1 (pt)
CA (1) CA2044700A1 (pt)
CZ (1) CZ282244B6 (pt)
DE (1) DE69130410T2 (pt)
DK (1) DK0462009T3 (pt)
ES (1) ES2124698T3 (pt)
FR (1) FR2663332B1 (pt)
HU (1) HUT58101A (pt)
IE (1) IE912032A1 (pt)
IL (3) IL114629A (pt)
NZ (1) NZ238577A (pt)
PT (1) PT97971B (pt)
RU (1) RU2078085C1 (pt)
SK (1) SK280156B6 (pt)
UA (1) UA26431A (pt)
ZA (1) ZA914457B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5397779A (en) * 1990-06-15 1995-03-14 Roussel-Uclaf Cephalosporins
US5587372A (en) * 1991-12-12 1996-12-24 Roussel Uclaf Cephalosporins
EP1016646A1 (fr) * 1991-12-12 2000-07-05 Hoechst Marion Roussel Nouveaux produits intermédiaires pour la préparation de céphalosporines comportant en position 7 un radical benzyloxyimino substitué
FR2699177A1 (fr) * 1992-12-11 1994-06-17 Roussel Uclaf Nouvelles céphalosporines comportant en position 7 un radical oxyimino substitué, leur procédé et intermédiaires de préparation et leur application comme médicaments.
EP0628562A1 (fr) * 1993-06-10 1994-12-14 Roussel Uclaf Céphalosporines comportant en position 7 un radical oxymino substitué, leurs intermédiaires, leurs procédé de préparation et leur application comme médicaments
KR100257130B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법
US7427680B2 (en) * 2001-01-12 2008-09-23 The Regents Of The University Of California Fluorogenic substrates for BETA-lactamase gene expression
KR0164458B1 (ko) * 1995-04-04 1999-01-15 김은영 암모니오세팔로스포린 계열 항생제 및 그의 제조방법
FR2737893B1 (fr) * 1995-08-16 1997-09-12 Roussel Uclaf Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede et intermediaires de preparation, leur application comme medicaments
US5872249A (en) * 1995-09-01 1999-02-16 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US7214825B2 (en) * 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
EP1706403B9 (en) 2003-12-22 2012-07-25 K.U.Leuven Research & Development Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
ATE426601T1 (de) 2004-12-21 2009-04-15 Gilead Sciences Inc Imidazoa4,5-cupyridinverbindung und verfahren zur antiviralen behandlung
WO2006104141A1 (ja) * 2005-03-29 2006-10-05 Shionogi & Co., Ltd. ３－プロペニルセフェム誘導体
ATE454384T1 (de) 2006-07-07 2010-01-15 Gilead Sciences Inc Neue pyridazinverbindung und ihre verwendung
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
CN114805394A (zh) * 2022-05-27 2022-07-29 山东普洛得邦医药有限公司 一种头孢克肟的合成方法
CN115260213A (zh) * 2022-05-27 2022-11-01 山东普洛得邦医药有限公司 一种头孢地尼的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
DE3650157T2 (de) * 1985-12-26 1995-05-04 Eisai Co Ltd Cephalosporin-verbindungen.
GB8623211D0 (en) * 1986-09-26 1986-10-29 Glaxo Group Ltd Chemical compounds
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
ATE212027T1 (de) * 1988-03-16 2002-02-15 Eisai Co Ltd Cephemderivate und verfahren zu ihrer herstellung
US5373001A (en) * 1990-06-15 1994-12-13 Roussel Uclaf Cephalosporins

Also Published As

Publication number Publication date
AU643289B2 (en) 1993-11-11
HUT58101A (en) 1992-01-28
FR2663332A1 (fr) 1991-12-20
DE69130410D1 (de) 1998-12-03
IL98318A (en) 1996-01-31
KR920000766A (ko) 1992-01-29
CA2044700A1 (fr) 1991-12-16
DK0462009T3 (da) 1999-07-05
CS183091A3 (en) 1992-10-14
ZA914457B (en) 1992-08-26
SK280156B6 (sk) 1999-09-10
UA26431A (uk) 1999-08-30
JP3080692B2 (ja) 2000-08-28
NZ238577A (en) 1992-04-28
ES2124698T3 (es) 1999-02-16
EP0462009A1 (fr) 1991-12-18
IE912032A1 (en) 1991-12-18
ATE172733T1 (de) 1998-11-15
KR960009266B1 (ko) 1996-07-16
PT97971B (pt) 1998-11-30
JPH04230289A (ja) 1992-08-19
CZ282244B6 (cs) 1997-06-11
DE69130410T2 (de) 1999-04-22
AU7837091A (en) 1991-12-19
EP0462009B1 (fr) 1998-10-28
FR2663332B1 (fr) 1997-11-07
IL114629A0 (en) 1995-11-27
HU911985D0 (en) 1991-12-30
US5416080A (en) 1995-05-16
RU2078085C1 (ru) 1997-04-27
IL98318A0 (en) 1992-06-21
IL114629A (en) 1997-06-10

Similar Documents

Publication Publication Date Title
PT97971A (pt) Processo para a preparacao de novas cefalosporinas possuindo um radiacl propenilo na posicao 3, substituido por um amonio quaternario e de composicoes farmaceuticas que os contem
PT91766A (pt) Processo para a preparacao de derivados do acido 3,5-dihidroxihept-6-ina-carboxilico substituidos na posicao, de seus compostos intermedios e de composicoes farmaceuticas que os contem
ES2081187T3 (es) Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
ES2123039T3 (es) Nuevas 3-(hidroxi-bencilidenil)-indolin-2-onas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
PT89520A (pt) Processo para a preparacao de derivados de quinolino e acido naftiridino-carboxilicos substituidos por alquilo na posicao 5 e substituidos por um anel de piperazina ou pirrolidina na posicao 7 e de composicoes farmaceuticas que os contem
PT95082A (pt) Processo para a preparacao de amino acidos isentos de lactamas e de composicoes farmaceuticas que os contem
PT99569A (pt) Processo para a preparacao de novos derivados de eritromicina e de composicoes farmaceuticas que os contem
PT91158A (pt) Processo para a preparacao de novos estirenos e carboxamidas heterociclicos biciclicos e composicoes farmaceuticas que os contem
PT96394A (pt) Processo para a preparacao de novos derivados do acido a-nor-esteroide-3-carboxilico e de composicoes farmaceuticas que os contem
PT98720A (pt) Processo para a preparacao de derivados de fosfolipidos de nucleosidos e de composicoes farmaceuticas que os contem
JPS6442500A (en) Novel derivative of 17-arylsteroid, manufacture and intermediate, use as drug and pharmaceutical composition
PT98905A (pt) Processo para a preparacao de mono-hidrato de furoato de mometasona,e de composicoes farmaceuticas que o contem
ES2128519T3 (es) Nuevas pirido-tiadiazinas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
PT95473A (pt) Processo para a preparacao de derivados de 24-homo-vitamina d e de composicoes farmaceuticas que os contem
ATE25847T1 (de) Derivate von pyridinium-thiomethylcephalosporinen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DK0434570T3 (da) Steroid-forbindelser med en substitueret thioethylgruppe i position 10, deres fremstilling og mellemprodukter herfra, forbindelserne anvendt som lægemidler samt farmaceutiske præparater med indhold heraf
PT93160A (pt) Processo para a preparacao de benzenossulfonamidas e de composicoes farmaceuticas que as contem
PT91364A (pt) Processo para a preparacao de derivados de 3-piperazinil-benzazol e de composicoes farmaceuticas que os contem
PT92180A (pt) Processo para a preparacao de novas mevalonolactonas do tipo tienopiridina e de composicoes farmaceuticas que as contem
ES2058963T3 (es) Dihidropiridinas substituidas heterociclicamente, procedimiento para su fabricacion y su uso en medicamentos.
PT87930A (pt) Processo para a preparacao de derivados de acido 3-desmetil-4-fluor-mevalonico e de composicoes farmaceuticas que os contem
PT95066A (pt) Processo para a preparacao de novos acidos omega-fenilamino alcanoicos substituidos e de composicoes farmaceuticas que os contem
MX9200651A (es) Nuevas feniletanolamino y feniletanolaminometil-tetralinas, proceso para su preparacion y composiciones farmaceuticas que las contienen
BR0008067A (pt) (1-fenaci-3-fenil-3-piperidiletil): derivados de piperidina, processo para obtê-los e composições farmacêuticas que os contêm
IL85425A (en) Anticonvulsant compositions containing substituted benzoyl anilides, some such novel compounds and process for their preparation

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19911114

FG3A Patent granted, date of granting

Effective date: 19980805

PC3A Transfer or assignment

Free format text: 19991011 HOECHST MARION ROUSSEL FR

PD3A Change of proprietorship

Owner name: ROUSSEL UCLAF

Effective date: 19991011

TE3A Change of address (patent)

Owner name: ROUSSEL UCLAF

Effective date: 19991011

PC3A Transfer or assignment

Free format text: AVENTIS PHARMA S.A. FR

Effective date: 20030110

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20050207