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PT97547A - Processo para a preparacao de novas pirido {2,3-f}{1,4}tiazepinas e pirido {3,2-b}{1,5}benzotiazepinas e de composicoes farmaceuticas que as contem - Google Patents

Processo para a preparacao de novas pirido {2,3-f}{1,4}tiazepinas e pirido {3,2-b}{1,5}benzotiazepinas e de composicoes farmaceuticas que as contem

Info

Publication number
PT97547A
PT97547A PT97547A PT9754791A PT97547A PT 97547 A PT97547 A PT 97547A PT 97547 A PT97547 A PT 97547A PT 9754791 A PT9754791 A PT 9754791A PT 97547 A PT97547 A PT 97547A
Authority
PT
Portugal
Prior art keywords
pyrid
tiazepins
benzotiazepins
preparation
new
Prior art date
Application number
PT97547A
Other languages
English (en)
Other versions
PT97547B (pt
Inventor
David J Wustsow
John H Dodd
Charles F Schwender
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of PT97547A publication Critical patent/PT97547A/pt
Publication of PT97547B publication Critical patent/PT97547B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT97547A 1990-05-03 1991-05-02 Processo para a preparacao de novas pirido {2,3-f}{1,4}tiazepinas e pirido {3,2-b}{1,5}benzotiazepinas e de composicoes farmaceuticas que as contem PT97547B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/518,351 US5075440A (en) 1990-05-03 1990-05-03 Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzothiazepines

Publications (2)

Publication Number Publication Date
PT97547A true PT97547A (pt) 1992-01-31
PT97547B PT97547B (pt) 1998-08-31

Family

ID=24063558

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97547A PT97547B (pt) 1990-05-03 1991-05-02 Processo para a preparacao de novas pirido {2,3-f}{1,4}tiazepinas e pirido {3,2-b}{1,5}benzotiazepinas e de composicoes farmaceuticas que as contem

Country Status (25)

Country Link
US (1) US5075440A (pt)
EP (1) EP0462696B1 (pt)
JP (1) JP3296499B2 (pt)
KR (1) KR100195345B1 (pt)
CN (2) CN1034077C (pt)
AT (1) ATE126231T1 (pt)
AU (1) AU651580B2 (pt)
CA (1) CA2041594C (pt)
DE (1) DE69111915T2 (pt)
DK (1) DK0462696T3 (pt)
ES (1) ES2079570T3 (pt)
FI (1) FI95912C (pt)
GR (1) GR3017305T3 (pt)
HK (1) HK51496A (pt)
HU (1) HU218909B (pt)
IE (1) IE68524B1 (pt)
IL (6) IL97999A (pt)
MY (1) MY106552A (pt)
NO (1) NO179411C (pt)
NZ (1) NZ237988A (pt)
PT (1) PT97547B (pt)
TN (1) TNSN91030A1 (pt)
TW (1) TW218878B (pt)
ZA (1) ZA913319B (pt)
ZW (1) ZW5291A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0100112A3 (en) * 1997-12-18 2004-05-28 Abbott Lab Fused pyridine derivatives having potassium chanel opening activity and their use
US6265417B1 (en) 1997-12-18 2001-07-24 Abbott Laboratories Potassium channel openers
US6593335B1 (en) 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
JPH11193289A (ja) * 1997-12-26 1999-07-21 Suntory Ltd ピロールスルホンアミド誘導体
US6482854B1 (en) * 1999-03-25 2002-11-19 Massachusetts Eye And Ear Infirmary Glaucoma treatment
US7015212B1 (en) 1999-05-12 2006-03-21 The United States Of America As Represented By The Department Of Health And Human Services Thiazepine inhibitors of HIV-1 integrase
ATE250067T1 (de) * 1999-06-14 2003-10-15 Ortho Mcneil Pharm Inc Dithiepino(6,5-b)pyridine und diese verwendete zusamensetzungen und methode
HK1045506B (en) 1999-07-12 2006-02-03 Ortho-Mcneil Pharmaceutical, Inc. Oxathiepino 6,5- i b /i ]dihydropyridines, and related compositions and methods
WO2001021621A1 (en) * 1999-09-22 2001-03-29 Ortho-Mcneil Pharmaceutical, Inc. BENZO-FUSED DITHIEPINO[6,5-b]PYRIDINES, AND RELATED COMPOSITIONS AND METHODS
US6410553B1 (en) 2000-01-12 2002-06-25 Ortho-Mcneil Pharmaceutical, Inc. Benzosulfones and related compositions and methods
AU783503B2 (en) * 2000-01-27 2005-11-03 Ortho-Mcneil Pharmaceutical, Inc. Benzoxathiepino(3,4-b)pyridine derivatives, process for their preparation and their use as medicaments
AU4732001A (en) 2000-03-23 2001-10-03 Ortho Mcneil Pharm Inc Thiepino (3,2-b) dihydropyridines and related compositions and methods
CN1680324A (zh) 2000-05-30 2005-10-12 奥索-麦克尼尔药品公司 二氢吡啶软药及相关组合物和方法
KR101233139B1 (ko) 2011-04-21 2013-02-21 주식회사 한서켐 라세믹 1,4-티아제핀 화합물의 분할 방법
CN107454842A (zh) * 2014-12-30 2017-12-08 莫尔瑟瑞克斯股份有限公司 新型钙调节剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1587128A (en) * 1977-04-07 1981-04-01 Hexachimie Benzothiazepine derivatives
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
FR2511683A1 (fr) * 1981-08-20 1983-02-25 Hexachimie Nouveaux derives de la pyrido (2,3-b) benzothiazepine(1,5) substituee en 5 par une carboxypiperazine, leur procede de preparation, leur application en therapeutique
EP0225175A3 (en) * 1985-11-28 1988-12-28 FISONS plc Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
GR3017305T3 (en) 1995-12-31
DE69111915D1 (de) 1995-09-14
NO179411C (no) 1996-10-02
IL97999A0 (en) 1992-06-21
ZA913319B (en) 1993-01-27
AU7635491A (en) 1991-11-07
ATE126231T1 (de) 1995-08-15
TNSN91030A1 (fr) 1992-10-25
CA2041594A1 (en) 1991-11-04
ES2079570T3 (es) 1996-01-16
IL127047A0 (en) 1999-09-22
NZ237988A (en) 1992-09-25
US5075440A (en) 1991-12-24
JPH04225986A (ja) 1992-08-14
CN1118783A (zh) 1996-03-20
FI95912C (fi) 1996-04-10
CN1056880A (zh) 1991-12-11
IE68524B1 (en) 1996-06-26
IL120447A0 (en) 1997-07-13
CN1039416C (zh) 1998-08-05
ZW5291A1 (en) 1993-01-06
TW218878B (pt) 1994-01-11
HU911476D0 (en) 1991-11-28
NO179411B (no) 1996-06-24
FI95912B (fi) 1995-12-29
JP3296499B2 (ja) 2002-07-02
KR100195345B1 (ko) 1999-06-15
HU218909B (hu) 2000-12-28
DK0462696T3 (da) 1995-09-18
EP0462696B1 (en) 1995-08-09
IL120447A (en) 1999-12-22
IL120446A (en) 2000-08-31
HK51496A (en) 1996-03-29
CA2041594C (en) 2002-07-23
NO911723D0 (no) 1991-05-02
IE911488A1 (en) 1991-11-06
AU651580B2 (en) 1994-07-28
DE69111915T2 (de) 1996-01-04
IL120446A0 (en) 1997-07-13
IL127047A (en) 2000-10-31
EP0462696A1 (en) 1991-12-27
KR910020019A (ko) 1991-12-19
PT97547B (pt) 1998-08-31
CN1034077C (zh) 1997-02-19
NO911723L (no) 1991-11-04
MY106552A (en) 1995-06-30
FI912124A0 (fi) 1991-05-02
FI912124A7 (fi) 1991-11-04
IL97999A (en) 1997-06-10
HUT60745A (en) 1992-10-28

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Legal Events

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BB1A Laying open of patent application

Effective date: 19910925

FG3A Patent granted, date of granting

Effective date: 19980518

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20081118