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PT920873E - Solucoes estabilizadas de teriparatida - Google Patents

Solucoes estabilizadas de teriparatida

Info

Publication number
PT920873E
PT920873E PT98123225T PT98123225T PT920873E PT 920873 E PT920873 E PT 920873E PT 98123225 T PT98123225 T PT 98123225T PT 98123225 T PT98123225 T PT 98123225T PT 920873 E PT920873 E PT 920873E
Authority
PT
Portugal
Prior art keywords
stabilized solution
solution solutions
solutions
stabilized
solution
Prior art date
Application number
PT98123225T
Other languages
English (en)
Inventor
Chin-Ming Chang
Henry A Havel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22086574&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT920873(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PT920873E publication Critical patent/PT920873E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/29—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
PT98123225T 1997-12-09 1998-12-07 Solucoes estabilizadas de teriparatida PT920873E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6907597P 1997-12-09 1997-12-09

Publications (1)

Publication Number Publication Date
PT920873E true PT920873E (pt) 2004-06-30

Family

ID=22086574

Family Applications (2)

Application Number Title Priority Date Filing Date
PT3104219T PT1417972E (pt) 1997-12-09 1998-12-07 Soluções estabilizadas de teriparatida
PT98123225T PT920873E (pt) 1997-12-09 1998-12-07 Solucoes estabilizadas de teriparatida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT3104219T PT1417972E (pt) 1997-12-09 1998-12-07 Soluções estabilizadas de teriparatida

Country Status (31)

Country Link
EP (2) EP0920873B1 (pt)
JP (1) JP4405666B2 (pt)
KR (1) KR100482703B1 (pt)
CN (1) CN1198644C (pt)
AR (1) AR018526A1 (pt)
AT (1) ATE260113T1 (pt)
AU (1) AU759726B2 (pt)
BR (1) BR9813463A (pt)
CA (1) CA2314313C (pt)
CY (1) CY1114000T1 (pt)
CZ (1) CZ302401B6 (pt)
DE (1) DE69821872T2 (pt)
DK (2) DK0920873T3 (pt)
EA (1) EA004761B1 (pt)
EG (1) EG23675A (pt)
ES (2) ES2215268T3 (pt)
HU (1) HU230784B1 (pt)
ID (1) ID27741A (pt)
IL (1) IL136662A (pt)
MY (1) MY120063A (pt)
NO (1) NO327302B1 (pt)
NZ (1) NZ505222A (pt)
PE (1) PE20000001A1 (pt)
PL (1) PL194268B1 (pt)
PT (2) PT1417972E (pt)
SK (1) SK288203B6 (pt)
TR (1) TR200002134T2 (pt)
TW (1) TW570811B (pt)
UA (1) UA72884C2 (pt)
WO (1) WO1999029337A1 (pt)
ZA (1) ZA9811127B (pt)

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AR033639A1 (es) 1998-08-19 2004-01-07 Lilly Co Eli Uso de hormonas paratiroideas para preparar medicamentos para reducir el riesgo de fracturas oseas vertebrales o no vertebrales en seres humanos con riesgo de padecer o que padecen osteoporosis
US7022674B2 (en) 1999-12-16 2006-04-04 Eli Lilly And Company Polypeptide compositions with improved stability
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WO2002098445A1 (fr) * 2001-05-30 2002-12-12 Chugai Seiyaku Kabushiki Kaisha Preparation de proteines
WO2003039331A2 (en) * 2001-11-05 2003-05-15 Eli Lilly And Company Method for improving stability of a bone-connecting implant
EP1767213A3 (en) * 2001-11-05 2007-04-25 Eli Lilly & Company Method for improving stability of a bone-connecting implant
US8088734B2 (en) 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US7741268B2 (en) 2003-04-02 2010-06-22 Ares Trading S.A. Liquid pharmaceutical formulations of FSH and LH together with a non-ionic surfactant
WO2004112826A1 (en) 2003-06-20 2004-12-29 Ares Trading Sa Freeze-dried fsh / lh formulations
BR0318454A (pt) 2003-08-08 2006-09-12 Abgenix Inc anticorpos dirigidos a hormÈnio da paratireóide (pth) e seus usos
US7318925B2 (en) 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
US7329725B1 (en) 2003-10-29 2008-02-12 Nastech Pharmaceutical Company Inc. Phage displayed Trp cage ligands
HUE043210T2 (hu) 2003-11-20 2019-08-28 Novo Nordisk As Injekciós eszközök elõállítására optimális propilénglikol-tartalmú peptidkészítmények
CA2547343C (en) 2003-12-23 2013-05-14 Infinity Pharmaceuticals, Inc. Analogs of benzoquinone-containing ansamycins for the treatment of cancer
US8268791B2 (en) 2004-08-25 2012-09-18 Aegis Therapeutics, Llc. Alkylglycoside compositions for drug administration
US9114069B2 (en) 2004-08-25 2015-08-25 Aegis Therapeutics, Llc Antibacterial compositions for drug administration
US9895444B2 (en) 2004-08-25 2018-02-20 Aegis Therapeutics, Llc Compositions for drug administration
US20140162965A1 (en) 2004-08-25 2014-06-12 Aegis Therapeutics, Inc. Compositions for oral drug administration
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US8642564B2 (en) 2004-08-25 2014-02-04 Aegis Therapeutics, Llc Compositions for drug administration
EP2457580A1 (en) * 2004-08-25 2012-05-30 The UAB Research Foundation Absorption enhancers for drug administration
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WO2007059470A2 (en) 2005-11-10 2007-05-24 Board Of Control Of Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
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US8895546B2 (en) 2009-03-27 2014-11-25 Hale Biopharma Ventures, Llc Administration of benzodiazepine compositions
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CA2782640A1 (en) 2009-12-07 2011-06-16 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
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CN103301058A (zh) * 2013-06-17 2013-09-18 深圳翰宇药业股份有限公司 一种特立帕肽注射用组合物及其制备方法和制剂
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CN106309358A (zh) * 2015-06-29 2017-01-11 成都金凯生物技术有限公司 含有人甲状旁腺激素的药物组合物及其制备方法与用途
JP6634758B2 (ja) * 2015-09-25 2020-01-22 ニプロ株式会社 液体組成物及び凍結乾燥製剤
KR20250044469A (ko) 2016-03-01 2025-03-31 아센디스 파마 본 디지즈 에이/에스 Pth 프로드럭
CN109789221B (zh) 2016-09-29 2022-11-01 阿森迪斯药物骨疾病股份有限公司 控释pth的药物组合物
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JP6577683B2 (ja) * 2017-09-22 2019-09-18 旭化成ファーマ株式会社 安定性に優れるテリパラチド含有液状医薬組成物
JP2019060866A (ja) * 2017-09-22 2019-04-18 旭化成ファーマ株式会社 液状医薬組成物の体内動態を予測する方法
CA3167644A1 (en) * 2017-09-22 2019-03-28 Asahi Kasei Pharma Corporation Teriparatide-containing liquid pharmaceutical composition having excellent pharmacokinetics and/or safety
CN108159404B (zh) * 2018-01-05 2019-08-27 北京博康健基因科技有限公司 重组人甲状旁腺激素制剂及其制备方法
WO2019220654A1 (ja) * 2018-05-17 2019-11-21 旭化成ファーマ株式会社 Ｎ－ホルミルピぺリジン含有量が低減されている、及び／又は、凍結乾燥ケーキの崩潰又は収縮が抑制されている、製剤
KR20250171437A (ko) 2019-02-11 2025-12-08 아센디스 파마 본 디지즈 에이/에스 Pth 접합체의 액체 약학 제제
CN112439054B (zh) * 2019-08-28 2023-05-16 深圳翰宇药业股份有限公司 一种特立帕肽缓释凝胶注射液及其制备方法
JP7761567B2 (ja) 2020-02-18 2025-10-28 ノヴォ ノルディスク アー／エス 医薬製剤
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Also Published As

Publication number Publication date
IL136662A0 (en) 2001-06-14
TR200002134T2 (tr) 2000-11-21
AU759726B2 (en) 2003-04-17
SK288203B6 (sk) 2014-07-02
PE20000001A1 (es) 2000-01-17
IL136662A (en) 2004-09-27
NO20002945D0 (no) 2000-06-08
EP1417972A1 (en) 2004-05-12
NZ505222A (en) 2003-05-30
BR9813463A (pt) 2000-10-10
EG23675A (en) 2007-04-15
DE69821872T2 (de) 2005-01-05
MY120063A (en) 2005-08-30
EP0920873A3 (en) 1999-08-04
EP0920873B1 (en) 2004-02-25
PL194268B1 (pl) 2007-05-31
EA200000629A1 (ru) 2000-12-25
ES2405994T3 (es) 2013-06-04
CN1198644C (zh) 2005-04-27
JP4405666B2 (ja) 2010-01-27
DE69821872D1 (de) 2004-04-01
AU1717799A (en) 2005-05-16
HU230784B1 (en) 2018-05-02
DK1417972T3 (da) 2013-05-13
CA2314313A1 (en) 1999-06-17
JP2001525372A (ja) 2001-12-11
KR100482703B1 (ko) 2005-04-14
NO327302B1 (no) 2009-06-02
EA004761B1 (ru) 2004-08-26
EP0920873A2 (en) 1999-06-09
UA72884C2 (uk) 2005-05-16
AR018526A1 (es) 2001-11-28
TW570811B (en) 2004-01-11
WO1999029337A1 (en) 1999-06-17
SK15322000A3 (sk) 2001-05-10
EP1417972B1 (en) 2013-04-10
ES2215268T3 (es) 2004-10-01
HUP0004447A2 (hu) 2001-04-28
HK1021798A1 (en) 2000-07-07
NO20002945L (no) 2000-07-07
ID27741A (id) 2001-04-26
DK0920873T3 (da) 2004-06-28
PT1417972E (pt) 2013-05-24
ZA9811127B (en) 2000-07-11
PL340902A1 (en) 2001-03-12
CZ302401B6 (cs) 2011-05-04
CN1281370A (zh) 2001-01-24
EP1417972B2 (en) 2018-08-22
CY1114000T1 (el) 2016-07-27
CA2314313C (en) 2005-02-08
HUP0004447A3 (en) 2003-06-30
ES2405994T5 (es) 2019-01-30
KR20010032881A (ko) 2001-04-25
ATE260113T1 (de) 2004-03-15
DK1417972T4 (en) 2018-10-22
CZ20002115A3 (en) 2001-05-16

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