PT92031A - Processo para a preparacao de 4-0-alquil-rodomicinas - Google Patents
Processo para a preparacao de 4-0-alquil-rodomicinasInfo
- Publication number
- PT92031A PT92031A PT92031A PT9203189A PT92031A PT 92031 A PT92031 A PT 92031A PT 92031 A PT92031 A PT 92031A PT 9203189 A PT9203189 A PT 9203189A PT 92031 A PT92031 A PT 92031A
- Authority
- PT
- Portugal
- Prior art keywords
- alkyl
- group
- acyl
- protective group
- rhodomycins
- Prior art date
Links
- 125000006239 protecting group Chemical group 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000003668 acetyloxy group Chemical group [H]C([H])([H])C(=O)O[*] 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 229910003849 O-Si Inorganic materials 0.000 abstract 1
- 229910003872 O—Si Inorganic materials 0.000 abstract 1
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical group OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 125000003232 p-nitrobenzoyl group Chemical group [N+](=O)([O-])C1=CC=C(C(=O)*)C=C1 0.000 abstract 1
- -1 p-nitrobenzoyloxy group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
- C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
- C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
- C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3836122A DE3836122A1 (de) | 1988-10-22 | 1988-10-22 | Verfahren zur herstellung von 4-0-alkyl-rhodomycinen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT92031A true PT92031A (pt) | 1990-04-30 |
| PT92031B PT92031B (pt) | 1995-06-30 |
Family
ID=6365756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT92031A PT92031B (pt) | 1988-10-22 | 1989-10-19 | Processo para a preparacao de 4-0-alquil-rodomicinas |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0365973B1 (pt) |
| JP (1) | JPH02164840A (pt) |
| KR (1) | KR900006358A (pt) |
| AT (1) | ATE98626T1 (pt) |
| AU (1) | AU4356689A (pt) |
| CA (1) | CA2001087A1 (pt) |
| DE (2) | DE3836122A1 (pt) |
| DK (1) | DK523189A (pt) |
| PT (1) | PT92031B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3943029A1 (de) * | 1989-12-27 | 1991-07-04 | Behringwerke Ag | Verfahren zur herstellung von glycosyl-anthracyclinonen |
| EP3771013B1 (en) * | 2018-03-23 | 2023-03-22 | Tomiyama Pure Chemical Industries, Limited | Electrolyte for power storage devices and nonaqueous electrolyte solution |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3641835A1 (de) * | 1986-12-08 | 1988-06-16 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
| DE3641833A1 (de) * | 1986-12-08 | 1988-06-09 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
| DE3712350A1 (de) * | 1987-04-11 | 1988-10-20 | Behringwerke Ag | Semisynthetische rhodomycine, verfahren zu ihrer herstellung und ihre verwendung als zytostatika |
-
1988
- 1988-10-22 DE DE3836122A patent/DE3836122A1/de not_active Ceased
-
1989
- 1989-10-17 EP EP89119222A patent/EP0365973B1/de not_active Expired - Lifetime
- 1989-10-17 AT AT89119222T patent/ATE98626T1/de not_active IP Right Cessation
- 1989-10-17 DE DE89119222T patent/DE58906440D1/de not_active Expired - Fee Related
- 1989-10-19 PT PT92031A patent/PT92031B/pt not_active IP Right Cessation
- 1989-10-20 JP JP1271937A patent/JPH02164840A/ja active Pending
- 1989-10-20 CA CA002001087A patent/CA2001087A1/en not_active Abandoned
- 1989-10-20 AU AU43566/89A patent/AU4356689A/en not_active Abandoned
- 1989-10-20 DK DK523189A patent/DK523189A/da not_active Application Discontinuation
- 1989-10-20 KR KR1019890015079A patent/KR900006358A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ATE98626T1 (de) | 1994-01-15 |
| PT92031B (pt) | 1995-06-30 |
| EP0365973B1 (de) | 1993-12-15 |
| KR900006358A (ko) | 1990-05-08 |
| JPH02164840A (ja) | 1990-06-25 |
| DK523189D0 (da) | 1989-10-20 |
| DE58906440D1 (de) | 1994-01-27 |
| DE3836122A1 (de) | 1990-05-31 |
| CA2001087A1 (en) | 1990-04-22 |
| EP0365973A1 (de) | 1990-05-02 |
| DK523189A (da) | 1990-04-23 |
| AU4356689A (en) | 1990-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960630 |