PT928191E - Formulacoes farmaceuticas compreendendo derivados de s-alquilisotiouronio - Google Patents
Formulacoes farmaceuticas compreendendo derivados de s-alquilisotiouronioInfo
- Publication number
- PT928191E PT928191E PT97941178T PT97941178T PT928191E PT 928191 E PT928191 E PT 928191E PT 97941178 T PT97941178 T PT 97941178T PT 97941178 T PT97941178 T PT 97941178T PT 928191 E PT928191 E PT 928191E
- Authority
- PT
- Portugal
- Prior art keywords
- pct
- alkylisoyouronium
- derivatives
- pharmaceutical formulations
- sec
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000032843 Hemorrhage Diseases 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 208000011861 acute hypotension Diseases 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000222 hyperoxic effect Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 231100000572 poisoning Toxicity 0.000 abstract 1
- 230000000607 poisoning effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000035939 shock Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU96119163A RU2142796C1 (ru) | 1996-09-26 | 1996-09-26 | Лекарственное противошоковое средство |
| RU97115433/14A RU2187309C2 (ru) | 1997-09-19 | 1997-09-19 | Средство, влияющее на артериальное давление |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT928191E true PT928191E (pt) | 2003-01-31 |
Family
ID=26653892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97941178T PT928191E (pt) | 1996-09-26 | 1997-09-25 | Formulacoes farmaceuticas compreendendo derivados de s-alquilisotiouronio |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6160008A (pt) |
| EP (1) | EP0928191B1 (pt) |
| JP (1) | JP4260888B2 (pt) |
| KR (1) | KR100575507B1 (pt) |
| CN (1) | CN1116871C (pt) |
| AT (1) | ATE222758T1 (pt) |
| AU (1) | AU717712B2 (pt) |
| BR (1) | BR9712851A (pt) |
| CA (1) | CA2266533C (pt) |
| DE (1) | DE69715013T2 (pt) |
| DK (1) | DK0928191T3 (pt) |
| ES (1) | ES2182116T3 (pt) |
| IL (1) | IL129020A (pt) |
| NO (1) | NO326600B1 (pt) |
| PT (1) | PT928191E (pt) |
| TR (1) | TR199900783T2 (pt) |
| WO (1) | WO1998013036A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0113698A (pt) | 2000-09-05 | 2003-12-09 | Meditor Pharmaceuticals Ltd | Composições farmacêuticas para dor de cabeça, enxaqueca, náusea e emese |
| US20090018206A1 (en) * | 2005-09-06 | 2009-01-15 | Meditor Pharmaceuticals Ltd. | Prevention of hypotension and stabilization of blood pressure in hemodialysis patients |
| US20090186854A1 (en) * | 2006-03-23 | 2009-07-23 | Meditor Pharmaceuticals Ltd. | S-alkylisothiouronium derivatives for the treatment of inflammatory diseases |
| US20100285127A1 (en) * | 2007-06-13 | 2010-11-11 | Refael Barkan | Taste masked pharmaceutical compositions of s-alkylisothiouronium derivatives |
| US12011423B2 (en) | 2007-11-06 | 2024-06-18 | Foraviset Ltd. | S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders |
| WO2009060451A2 (en) * | 2007-11-06 | 2009-05-14 | Barkan-Farma S.R.L. | S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders |
| MD3619G2 (ro) * | 2007-11-06 | 2009-01-31 | Рафаэль Баркан | Remediu medicamentos nazal cu acţiune anticongestivă |
| CN104140386A (zh) * | 2014-02-12 | 2014-11-12 | 上海应用技术学院 | 一种2-苄基-异硫脲三氟乙酸盐的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3123636A (en) * | 1964-03-03 | Thiuronium h alii | ||
| US3116327A (en) * | 1960-07-22 | 1963-12-31 | Baxter Laboratories Inc | Upsilon-dimethylaminopropyl isothiourea and acid addition salts thereof |
| US3657337A (en) * | 1967-12-04 | 1972-04-18 | Sandoz Ag | Benzylideneamino guanidines |
| FR2419675A1 (fr) * | 1978-03-16 | 1979-10-12 | Philagro Sa | Compositions fongicides a base de phosphites d'isothiouronium |
| AT395012B (de) * | 1986-06-27 | 1992-08-25 | Richter Gedeon Vegyeszet | Verfahren zur herstellung von n-(1(s)|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen |
-
1997
- 1997-09-25 JP JP51546498A patent/JP4260888B2/ja not_active Expired - Fee Related
- 1997-09-25 DK DK97941178T patent/DK0928191T3/da active
- 1997-09-25 US US09/269,405 patent/US6160008A/en not_active Expired - Fee Related
- 1997-09-25 ES ES97941178T patent/ES2182116T3/es not_active Expired - Lifetime
- 1997-09-25 PT PT97941178T patent/PT928191E/pt unknown
- 1997-09-25 BR BR9712851-1A patent/BR9712851A/pt not_active IP Right Cessation
- 1997-09-25 TR TR1999/00783T patent/TR199900783T2/xx unknown
- 1997-09-25 DE DE69715013T patent/DE69715013T2/de not_active Expired - Lifetime
- 1997-09-25 KR KR1019997002578A patent/KR100575507B1/ko not_active Expired - Fee Related
- 1997-09-25 CA CA002266533A patent/CA2266533C/en not_active Expired - Fee Related
- 1997-09-25 CN CN97199137A patent/CN1116871C/zh not_active Expired - Fee Related
- 1997-09-25 EP EP97941178A patent/EP0928191B1/en not_active Expired - Lifetime
- 1997-09-25 AU AU43178/97A patent/AU717712B2/en not_active Ceased
- 1997-09-25 IL IL12902097A patent/IL129020A/en not_active IP Right Cessation
- 1997-09-25 AT AT97941178T patent/ATE222758T1/de active
- 1997-09-25 WO PCT/IL1997/000314 patent/WO1998013036A1/en not_active Ceased
-
1999
- 1999-03-24 NO NO19991419A patent/NO326600B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP4260888B2 (ja) | 2009-04-30 |
| US6160008A (en) | 2000-12-12 |
| CA2266533A1 (en) | 1998-04-02 |
| AU717712B2 (en) | 2000-03-30 |
| KR100575507B1 (ko) | 2006-05-03 |
| WO1998013036A1 (en) | 1998-04-02 |
| IL129020A (en) | 2004-06-20 |
| CN1234737A (zh) | 1999-11-10 |
| KR20000048636A (ko) | 2000-07-25 |
| BR9712851A (pt) | 2000-01-18 |
| DE69715013T2 (de) | 2003-05-22 |
| EP0928191B1 (en) | 2002-08-28 |
| TR199900783T2 (xx) | 1999-07-21 |
| CA2266533C (en) | 2007-08-07 |
| HK1022833A1 (en) | 2000-08-25 |
| CN1116871C (zh) | 2003-08-06 |
| DE69715013D1 (de) | 2002-10-02 |
| ATE222758T1 (de) | 2002-09-15 |
| ES2182116T3 (es) | 2003-03-01 |
| IL129020A0 (en) | 2000-02-17 |
| NO991419L (no) | 1999-05-21 |
| AU4317897A (en) | 1998-04-17 |
| JP2001501928A (ja) | 2001-02-13 |
| EP0928191A1 (en) | 1999-07-14 |
| NO326600B1 (no) | 2009-01-19 |
| NO991419D0 (no) | 1999-03-24 |
| DK0928191T3 (da) | 2002-12-30 |
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