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BR9712851A - Composições farmacêuticas compreendendo derivados de salquilisotiourÈnio - Google Patents

Composições farmacêuticas compreendendo derivados de salquilisotiourÈnio

Info

Publication number
BR9712851A
BR9712851A BR9712851-1A BR9712851A BR9712851A BR 9712851 A BR9712851 A BR 9712851A BR 9712851 A BR9712851 A BR 9712851A BR 9712851 A BR9712851 A BR 9712851A
Authority
BR
Brazil
Prior art keywords
pct
salkylisothiourènium
derivatives
pharmaceutical compositions
sec
Prior art date
Application number
BR9712851-1A
Other languages
English (en)
Inventor
I Lev Mizrakh
I Victor Gikavy
V Valentin Znamensky
V Evgeni Arzamastsev
B Lev Shagalov
Valeri Kovtun
H Vladimir Jashounsky
V Victor Darchuk
G Marina Kochetkova
T Galina Bondareva
A Olga Terekhova
Original Assignee
Meditor Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU96119163A external-priority patent/RU2142796C1/ru
Priority claimed from RU97115433/14A external-priority patent/RU2187309C2/ru
Application filed by Meditor Pharmaceuticals Ltd filed Critical Meditor Pharmaceuticals Ltd
Publication of BR9712851A publication Critical patent/BR9712851A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçõES FARMACêUTICAS COMPREENDENDO DERIVADOS DE S-ALQUILISOTIOURÈNIO"<D>. Sais de S-alquilisotiourónio com ácidos contendo fósforo, incluindo diversos de tais novos compostos, os quais são para uso como medicamentos para aumentar a pressão sang³ínea arterial, ou para proteger contra a hiperoxia. Estes compostos podem ser usados para o tratamento de hipotensão aguda, por exemplo, condições de choque, hipotensão arterial crónica ou envenenamento por oxigênio.
BR9712851-1A 1996-09-26 1997-09-25 Composições farmacêuticas compreendendo derivados de salquilisotiourÈnio BR9712851A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU96119163A RU2142796C1 (ru) 1996-09-26 1996-09-26 Лекарственное противошоковое средство
RU97115433/14A RU2187309C2 (ru) 1997-09-19 1997-09-19 Средство, влияющее на артериальное давление
PCT/IL1997/000314 WO1998013036A1 (en) 1996-09-26 1997-09-25 Pharmaceutical compositions comprising s-alkylisothiouronium derivatives

Publications (1)

Publication Number Publication Date
BR9712851A true BR9712851A (pt) 2000-01-18

Family

ID=26653892

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9712851-1A BR9712851A (pt) 1996-09-26 1997-09-25 Composições farmacêuticas compreendendo derivados de salquilisotiourÈnio

Country Status (17)

Country Link
US (1) US6160008A (pt)
EP (1) EP0928191B1 (pt)
JP (1) JP4260888B2 (pt)
KR (1) KR100575507B1 (pt)
CN (1) CN1116871C (pt)
AT (1) ATE222758T1 (pt)
AU (1) AU717712B2 (pt)
BR (1) BR9712851A (pt)
CA (1) CA2266533C (pt)
DE (1) DE69715013T2 (pt)
DK (1) DK0928191T3 (pt)
ES (1) ES2182116T3 (pt)
IL (1) IL129020A (pt)
NO (1) NO326600B1 (pt)
PT (1) PT928191E (pt)
TR (1) TR199900783T2 (pt)
WO (1) WO1998013036A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60131004T2 (de) * 2000-09-05 2008-07-31 Meditor Pharmaceuticals Ltd. Pharmazeutische zubereitungen gegen kopfschmerz, migräne, nausea und erbrechen
US20090018206A1 (en) * 2005-09-06 2009-01-15 Meditor Pharmaceuticals Ltd. Prevention of hypotension and stabilization of blood pressure in hemodialysis patients
WO2007108004A2 (en) * 2006-03-23 2007-09-27 Meditor Pharmaceuticals Ltd. S-alkylisothiouronium derivatives for the treatment of inflammatory diseases
EP2167050A1 (en) * 2007-06-13 2010-03-31 Meditor Pharmaceuticals Ltd. Taste masked pharmaceutical compositions of s-alkylisothiouronium derivatives
EA030035B1 (ru) * 2007-11-06 2018-06-29 Меламед, Лемуил Применение s-этилизотиоурония диэтилфосфата для изготовления лекарственного средства для лечения нарушения матки
US12011423B2 (en) 2007-11-06 2024-06-18 Foraviset Ltd. S-alkylisothiouronium derivatives for treating uterine hypercontractility disorders
MD3619G2 (ro) * 2007-11-06 2009-01-31 Рафаэль Баркан Remediu medicamentos nazal cu acţiune anticongestivă
CN104140386A (zh) * 2014-02-12 2014-11-12 上海应用技术学院 一种2-苄基-异硫脲三氟乙酸盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3123636A (en) * 1964-03-03 Thiuronium h alii
US3116327A (en) * 1960-07-22 1963-12-31 Baxter Laboratories Inc Upsilon-dimethylaminopropyl isothiourea and acid addition salts thereof
US3657337A (en) * 1967-12-04 1972-04-18 Sandoz Ag Benzylideneamino guanidines
FR2419675A1 (fr) * 1978-03-16 1979-10-12 Philagro Sa Compositions fongicides a base de phosphites d'isothiouronium
AT395012B (de) * 1986-06-27 1992-08-25 Richter Gedeon Vegyeszet Verfahren zur herstellung von n-(1(s)|thoxycarbonyl-3-phenyl-propyl)-(s)-alanyl-(s)prolin und von dessen saeureadditionssalzen

Also Published As

Publication number Publication date
AU717712B2 (en) 2000-03-30
NO991419D0 (no) 1999-03-24
CA2266533A1 (en) 1998-04-02
NO991419L (no) 1999-05-21
DE69715013T2 (de) 2003-05-22
US6160008A (en) 2000-12-12
KR20000048636A (ko) 2000-07-25
IL129020A0 (en) 2000-02-17
CA2266533C (en) 2007-08-07
ES2182116T3 (es) 2003-03-01
CN1234737A (zh) 1999-11-10
ATE222758T1 (de) 2002-09-15
HK1022833A1 (en) 2000-08-25
CN1116871C (zh) 2003-08-06
JP4260888B2 (ja) 2009-04-30
EP0928191B1 (en) 2002-08-28
PT928191E (pt) 2003-01-31
NO326600B1 (no) 2009-01-19
WO1998013036A1 (en) 1998-04-02
JP2001501928A (ja) 2001-02-13
TR199900783T2 (xx) 1999-07-21
EP0928191A1 (en) 1999-07-14
DE69715013D1 (de) 2002-10-02
DK0928191T3 (da) 2002-12-30
KR100575507B1 (ko) 2006-05-03
AU4317897A (en) 1998-04-17
IL129020A (en) 2004-06-20

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 14A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 14A ANUIDADE.