PT91719A - Processo para a preparacao de novos derivados de factor de crescimento de fobroblastos basico humano/bovino - Google Patents

Processo para a preparacao de novos derivados de factor de crescimento de fobroblastos basico humano/bovino

Info

Publication number: PT91719A
Authority: PT; Portugal
Prior art keywords: derivatives; growth factor; bfgf; fobroblast; new human
Prior art date: 1988-09-16

Application number

PT91719A

Other languages

English (en)

Other versions

PT91719B (pt

Inventor

Paolo Sarmientos

Laura Bergonzoni

Antonella Isacchi

Gilles Cauet

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-16

Filing date

1989-09-14

Publication date

1990-03-30

1989-09-14 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1990-03-30 Publication of PT91719A publication Critical patent/PT91719A/pt

1995-05-31 Publication of PT91719B publication Critical patent/PT91719B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Dermatology (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Eye Examination Apparatus (AREA)

PT91719A 1988-09-16 1989-09-14 Processo para a preparacao de novos derivados de factor de crescimento de fobroblastos basico humano/bovino PT91719B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888821795A GB8821795D0 (en)	1988-09-16	1988-09-16	New derivatives of human/bovine basic fibroplast growth factor

Publications (2)

Publication Number	Publication Date
PT91719A true PT91719A (pt)	1990-03-30
PT91719B PT91719B (pt)	1995-05-31

Family

ID=10643728

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT91719A PT91719B (pt)	1988-09-16	1989-09-14	Processo para a preparacao de novos derivados de factor de crescimento de fobroblastos basico humano/bovino

Country Status (21)

Country	Link
EP (2)	EP0396664A1 (pt)
JP (1)	JP2888575B2 (pt)
KR (1)	KR900702027A (pt)
CN (1)	CN1041181A (pt)
AT (1)	ATE98693T1 (pt)
AU (1)	AU620925B2 (pt)
CA (1)	CA1340834C (pt)
DE (1)	DE68911461T2 (pt)
DK (1)	DK120290A (pt)
ES (1)	ES2061855T3 (pt)
FI (1)	FI902391A0 (pt)
GB (1)	GB8821795D0 (pt)
HU (1)	HUT53937A (pt)
IL (1)	IL91615A0 (pt)
MY (1)	MY104910A (pt)
NO (1)	NO902176L (pt)
NZ (1)	NZ230621A (pt)
PT (1)	PT91719B (pt)
WO (1)	WO1990002800A1 (pt)
YU (1)	YU179489A (pt)
ZA (1)	ZA897020B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5143829A (en) *	1990-03-29	1992-09-01	California Biotechnology Inc.	High level expression of basic fibroblast growth factor having a homogeneous n-terminus
US5478804A (en) *	1990-09-19	1995-12-26	The Salk Institute For Biological Studies	Treatment of tumorigenic pathophysiological conditions with FGF-cytoxic conjugates
JP3135138B2 (ja) *	1990-12-19	2001-02-13	科研製薬株式会社	骨疾患治療剤
US6833354B1 (en)	1990-12-19	2004-12-21	Kaken Pharmaceutical Co., Ltd.	Agent for the treatment of bone diseases
EP0505108B1 (en) *	1991-03-21	1995-10-18	The Procter & Gamble Company	Compositions for regulating skin wrinkles comprising an Arg-Ser-Arg-Lys based peptide
JP3303211B2 (ja) *	1991-04-26	2002-07-15	武田薬品工業株式会社	ｂＦＧＦムテインおよびその製造法
TW275068B (pt) *	1993-09-24	1996-05-01	American Cyanamid Co
AUPO247496A0 (en)	1996-09-23	1996-10-17	Resmed Limited	Assisted ventilation to match patient respiratory need
US6214795B1 (en)	1996-11-12	2001-04-10	Praecis Pharmaceuticals, Inc.	Peptide compounds useful for modulating FGF receptor activity
US6274712B1 (en)	1997-12-23	2001-08-14	3-Dimensional Pharmaceuticals, Inc.	Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
FR2780416B1 (fr) *	1998-06-10	2002-12-20	Rhone Poulenc Nutrition Animal	Procede industriel de production de proteines heterologues chez e. coli et souches utiles pour le procede
JP5704780B2 (ja)	1999-08-13	2015-04-22	ノバルティスバクシンズアンドダイアグノスティックス，インコーポレーテッド	脈管形成因子の用量および心筋血流を改善するための投与方法
AU2376000A (en) *	1999-12-22	2001-07-03	3-Dimensional Pharmaceuticals, Inc.	Analogs of human basic fibroblast growth factor
CA2430112C (en)	2000-11-27	2010-07-27	Dnavec Research Inc.	Paramyxovirus vector encoding angiogenesis gene and use thereof
WO2013090919A1 (en) *	2011-12-16	2013-06-20	Wisconsin Alumni Research Foundation	Fgf-2 having enhanced stability
CN106957359B (zh) *	2016-08-31	2020-04-24	黄志锋	Fgf1突变体及其医药应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1989000198A1 (en) *	1987-07-07	1989-01-12	Biotechnology Research Associates, J.V.	Recombinant fibroblast growth factors
IL81839A0 (en) *	1986-03-14	1987-10-20	Takeda Chemical Industries Ltd	Polypeptide,dna and its use
JPH01501840A (ja) *	1987-01-16	1989-06-29	アムジエン・インコーポレーテツド	繊維芽細胞成長因子の産生
JP2526965B2 (ja) *	1987-02-24	1996-08-21	武田薬品工業株式会社	ムテイン，ｄｎａおよびその用途
EP0326907A1 (en) *	1988-01-26	1989-08-09	Takeda Chemical Industries, Ltd.	Polypeptide, DNA and its use

1988
- 1988-09-16 GB GB888821795A patent/GB8821795D0/en active Pending
1989
- 1989-09-12 NZ NZ230621A patent/NZ230621A/en unknown
- 1989-09-12 IL IL91615A patent/IL91615A0/xx unknown
- 1989-09-14 MY MYPI89001258A patent/MY104910A/en unknown
- 1989-09-14 ZA ZA897020A patent/ZA897020B/xx unknown
- 1989-09-14 PT PT91719A patent/PT91719B/pt not_active IP Right Cessation
- 1989-09-14 CN CN89107069A patent/CN1041181A/zh active Pending
- 1989-09-14 CA CA000611335A patent/CA1340834C/en not_active Expired - Fee Related
- 1989-09-15 AU AU43171/89A patent/AU620925B2/en not_active Ceased
- 1989-09-15 ES ES89117112T patent/ES2061855T3/es not_active Expired - Lifetime
- 1989-09-15 DE DE68911461T patent/DE68911461T2/de not_active Expired - Fee Related
- 1989-09-15 FI FI902391A patent/FI902391A0/fi not_active IP Right Cessation
- 1989-09-15 JP JP1509755A patent/JP2888575B2/ja not_active Expired - Lifetime
- 1989-09-15 WO PCT/EP1989/001075 patent/WO1990002800A1/en not_active Ceased
- 1989-09-15 EP EP89910440A patent/EP0396664A1/en active Pending
- 1989-09-15 EP EP89117112A patent/EP0363675B1/en not_active Expired - Lifetime
- 1989-09-15 YU YU01794/89A patent/YU179489A/xx unknown
- 1989-09-15 AT AT89117112T patent/ATE98693T1/de not_active IP Right Cessation
- 1989-09-16 HU HU895573A patent/HUT53937A/hu unknown
1990
- 1990-05-15 NO NO90902176A patent/NO902176L/no unknown
- 1990-05-15 DK DK120290A patent/DK120290A/da not_active Application Discontinuation
- 1990-05-16 KR KR1019900701019A patent/KR900702027A/ko not_active Withdrawn

Also Published As

Publication number	Publication date
DE68911461T2 (de)	1994-05-19
EP0363675A1 (en)	1990-04-18
HU895573D0 (en)	1990-11-28
IL91615A0 (en)	1990-04-29
NO902176L (no)	1990-07-13
DE68911461D1 (de)	1994-01-27
WO1990002800A1 (en)	1990-03-22
CA1340834C (en)	1999-11-30
EP0396664A1 (en)	1990-11-14
KR900702027A (ko)	1990-12-05
FI902391A7 (fi)	1990-05-14
AU4317189A (en)	1990-04-02
FI902391A0 (fi)	1990-05-14
CN1041181A (zh)	1990-04-11
DK120290D0 (da)	1990-05-15
MY104910A (en)	1994-06-30
NZ230621A (en)	1992-06-25
NO902176D0 (no)	1990-05-15
DK120290A (da)	1990-07-16
AU620925B2 (en)	1992-02-27
ATE98693T1 (de)	1994-01-15
YU179489A (en)	1991-10-31
ES2061855T3 (es)	1994-12-16
ZA897020B (en)	1990-08-29
EP0363675B1 (en)	1993-12-15
JP2888575B2 (ja)	1999-05-10
PT91719B (pt)	1995-05-31
JPH03501855A (ja)	1991-04-25
HUT53937A (en)	1990-12-28
GB8821795D0 (en)	1988-10-19

Publication	Publication Date	Title
PT91719A (pt)	1990-03-30	Processo para a preparacao de novos derivados de factor de crescimento de fobroblastos basico humano/bovino
PT92278A (pt)	1990-05-31	Processo para a preparacao de proteinas de ligacao de factor de crescimento semelhante a insulina
MX172600B (es)	1994-01-03	, "procedimiento para la produccion de una proteina biologicamente activa
SG49097A1 (en)	1998-05-18	Nucleotide sequences coding for a protein with urease activity
ATE107958T1 (de)	1994-07-15	Herstellung eines insulinähnlichen, wachstümsfaktor bindenden proteins.
PL322945A1 (en)	1998-03-02	Novel protein and method of obtaining same
DE3750197D1 (de)	1994-08-18	Antagonisten des Fibroblasten-Wachstumsfaktors.
DE69828193D1 (de)	2005-01-20	Hyaluronan synthase gen und seine verwendung
ATE123949T1 (de)	1995-07-15	B-ketten-analoge des von blutplättchen abstammenden wachstumsfaktors und verfahren zu deren homogener herstellung.
ATE90944T1 (de)	1993-07-15	Fuer ein hirudinaehnliches protein kodierende dns- sequenz und verfahren zur herstellung eines solchen proteins.
PT92603A (pt)	1990-06-29	Processo de producao de factor de crescimento transformante, quimerico,beta
DE3850654D1 (de)	1994-08-18	Immunglobulin-e-kompetitor.
DE3854420D1 (de)	1995-10-12	Onkogen kodierendes polypeptid, das wachstumsfaktoraktivität besitzt, verfahren zu seiner herstellung und verwendung.
FI102383B1 (fi)	1998-11-30	Menetelmä ja plasmidi modifioidun PE40-domeenia sisältävän hybridiproteiinin valmistamiseksi
EP0315118A3 (en)	1990-09-19	Dna coding for endothelin and use thereof
EP0276778A3 (en)	1990-01-10	High level expression in e. coli of soluble mature hil-1beta and derivatives with altered biological activity
PT704527E (pt)	2003-09-30	Sequencias de adn que codificam precursores de insulina biossinteticos e processo para a preparacao de insulina
ES2044887T3 (es)	1994-01-16	Metodo para la preparacion de factor de crecimiento de tipo insulina i.
DE3856392D1 (de)	2000-02-24	Klonierung von Malaria-spezifischen DNA-Sequenzen:Isolierung des Gens für das 140 kd Protein
DE3900770A1 (de)	1990-07-26	Verfahren zur herstellung von pdgf-a und pdgf-aa
ATE158814T1 (de)	1997-10-15	Verfahren zur gentechnologischen herstellung von biologisch aktivem beta-ngf
Bergonzoni et al.	1995	Deletion mutant of basic fibroblast growth factor and production thereof
ATE130872T1 (de)	1995-12-15	Ancrod ähnliche proteine, ihre herstellung und verwendung.
ATE107694T1 (de)	1994-07-15	Für a.nidulans-isopenicillin-n-synthetase codierende dns, deren verwendung und dafür codierende vektoren.

Legal Events

Date	Code	Title	Description
1995-05-31	FG3A	Patent granted, date of granting	Effective date: 19941114
1996-09-30	MM3A	Annulment or lapse	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960531

Date

Code

Title

Description

1995-05-31

FG3A

Patent granted, date of granting

Effective date: 19941114

1996-09-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960531